KEGG   ORTHOLOGY: K13877
Entry
K13877                      KO                                     
Symbol
aldH
Name
2,5-dioxopentanoate dehydrogenase [EC:1.2.1.26]
Pathway
map00040  Pentose and glucuronate interconversions
map00053  Ascorbate and aldarate metabolism
map00470  D-Amino acid metabolism
map01100  Metabolic pathways
Module
M00948  Hydroxyproline degradation, trans-4-hydroxy-L-proline => 2-oxoglutarate
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09101 Carbohydrate metabolism
   00040 Pentose and glucuronate interconversions
    K13877  aldH; 2,5-dioxopentanoate dehydrogenase
   00053 Ascorbate and aldarate metabolism
    K13877  aldH; 2,5-dioxopentanoate dehydrogenase
  09106 Metabolism of other amino acids
   00470 D-Amino acid metabolism
    K13877  aldH; 2,5-dioxopentanoate dehydrogenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.2  Acting on the aldehyde or oxo group of donors
   1.2.1  With NAD+ or NADP+ as acceptor
    1.2.1.26  2,5-dioxovalerate dehydrogenase
     K13877  aldH; 2,5-dioxopentanoate dehydrogenase
Other DBs
RN: R00264
GO: 0047533
Genes
EAS: Entas_0544
KPY: KPNIH31_04595
KPI: D364_24440
KVA: Kvar_4455
KPE: KPK_4822(aldH)
KPK: A593_14040
KVD: KR75_11490
KVQ: SP68_18125
KQU: AVR78_07845
EAE: EAE_10400
EAR: CCG31914
RTG: NCTC13098_06401(aldH)
CRO: ROD_25491
SMAR: SM39_1305
SPE: Spro_1837
SRL: SOD_c16630(aldH)
SPLY: Q5A_009095
SMAF: D781_1747
SERF: L085_19540
SFJ: SAMEA4384070_1861(aldH)
SOD: Sant_2373(aldH)
PES: SOPEG_1553(aldH)
EAM: EAMY_2587
EAY: EAM_2482
EPY: EpC_10390
PLU: plu2246
PAY: PAU_02153
XCV: XCV2743
XAX: XACM_2526
XAC: XAC2546
XCI: XCAW_02225(putA)
XOM: XOO2978(XOO2978)
XOO: XOO3136(PutA)
XOP: PXO_01440
XOR: XOC_1910
XAL: XALC_1961
XPH: XppCFBP6546_19685(XppCFBP6546P_19685)
LEZ: GLE_4607
LEM: LEN_0614
VPA: VP1329
VPB: VPBB_1253
VAG: N646_0363
PMY: Pmen_0227
PMK: MDS_0274
PSB: Psyr_3157
PSYR: N018_15855
PFL: PFL_1415(aldH_1) PFL_1528(aldH_2)
PPRC: PFLCHA0_c14520(aldH1) PFLCHA0_c15670(aldH2)
PFC: PflA506_2248(aldH_1) PflA506_2820(aldH_2)
PSTT: CH92_12560
PKC: PKB_3090
PSEC: CCOS191_2359(aldH1) CCOS191_3998(aldH2b)
PSOS: POS17_1438
PALL: UYA_01000
PDW: BV82_1486
PSEP: C4K39_5250
PTAE: NCTC10697_01418(aldH_1) NCTC10697_01739(aldH_2) NCTC10697_01957(aldH_3) NCTC10697_02008(aldH_4) NCTC10697_02678(aldH_6)
ACX: Achr_3120
ABM: ABSDF1409
ACC: BDGL_000382(aldH) BDGL_000678(aldH) BDGL_001259(aldH) BDGL_001316(aldH)
ACI: ACIAD0131
SAZ: Sama_1529
SLO: Shew_2364
SSE: Ssed_1760
SPL: Spea_1702
SHL: Shal_2557
SWD: Swoo_2824
SWP: swp_1982
SVO: SVI_1708
SPSW: Sps_03407
SKH: STH12_01172(aldH)
CPS: CPS_1451(aldH)
PTN: PTRA_b0295(aldH)
PSEO: OM33_13460
PSPO: PSPO_a2279(aldH)
PTU: PTUN_a1049(aldH)
PSEN: PNC201_08060(aldH)
PSAZ: PA25_17400(aldH)
FBL: Fbal_2402
SAGA: M5M_19245
CSA: Csal_1140
CVI: CV_2824
PSE: NH8B_1450
AMAH: DLM_1556
RSO: RSp0827
RSL: RPSI07_mp0771(aldH)
RSN: RSPO_m01145(aldH)
RSM: CMR15_mp10803(aldH)
RSE: F504_4392
RPI: Rpic_4451
REH: H16_B0130(h16_B0130) H16_B0212(h16_B0212) H16_B0322(h16_B0322)
CNC: CNE_2c01150 CNE_2c01970(aldH1) CNE_2c03400(aldH2)
RME: Rmet_0832(aldH)
CGD: CR3_0768(aldH) CR3_3976(aldH)
BMAL: DM55_3664
BMAQ: DM76_4360
BXE: Bxe_B1805
BXB: DR64_7111
PPNO: DA70_20740
PPNM: LV28_09635
PPUL: RO07_03810
PSPU: NA29_24800
PAPI: SG18_03990
PLG: NCTC10937_02223(aldH_1) NCTC10937_02839(aldH_2)
CABA: SBC2_66660(LhpG) SBC2_68740
BPAR: BN117_1238
BPA: BPP2085
BBR: BB1481
BPT: Bpet1258
AXX: ERS451415_02953(aldH)
AMIM: MIM_c20070
AAA: Acav_4664
ACRA: BSY15_1620
HPSE: HPF_05200(aldH)
LCH: Lcho_2460
URU: DSM104443_02578(lhpG)
ALK: ALEK_0475
MXA: MXAN_6204
SCL: sce8242(aldH)
MES: Meso_0844
SME: SM_b20262
SMI: BN406_06404(aldH)
SMER: DU99_32060
EAD: OV14_b0363(hpaE)
ATU: Atu3259
ARA: Arad_4081
ATF: Ach5_31040(aldH)
AVI: Avi_3912
RLE: RL2296(aldH) pRL120235
RIR: BN877_II1588(aldH)
SHZ: shn_20840
XAU: Xaut_3374
MAQU: Maq22A_c11780(putA) Maq22A_c17960(putA)
MIND: mvi_36280
BID: Bind_3078
HDI: HDIA_4619(aldH_1) HDIA_P0039(aldH_2)
MMED: Mame_00342(aldH_1) Mame_00561(aldH_2) Mame_00810(aldH_3)
PSF: PSE_p0205
CCR: CC_2791
CSE: Cseg_0982
DSH: Dshi_2442(aldH1)
KVL: KVU_0810
OTM: OSB_21610
CID: P73_1648
SPSE: SULPSESMR1_03843(gabD)
RID: RIdsm_00840(aldH)
MARU: FIU81_05395(aldH)
RSP: RSP_3656
PAMN: pAMV1p0046(araE)
PTP: RCA23_c06710(aldH)
RHC: RGUI_2119
LVS: LOKVESSMR4R_03076(astD)
SPHU: SPPYR_0552(aldH)
SPHM: G432_06470
STAX: MC45_10350
SPHI: TS85_16940
SSAN: NX02_07120
SINB: SIDU_10705
SSY: SLG_18210
SPMI: K663_01045
SPHB: EP837_01502(aldH)
SPHR: BSY17_2380
SPHT: K426_16890
SMIC: SmB9_33230
AAY: WYH_02188(aldH)
ADO: A6F68_00834(aldH)
ERF: FIU90_14305(aldH)
ACR: Acry_0197
TMO: TMO_a0251(aldH)
MMC: Mmcs_4783
MKM: Mkms_4869
MJL: Mjls_5169
MVA: Mvan_1031
MAUU: NCTC10437_00825(aldH)
MARZ: MARA_46670
MPOF: MPOR_13310
MBOK: MBOE_05940
CGL: Cgl0452(Cgl0452)
CGB: cg0535
CGU: WA5_0437
CGT: cgR_0525
CGM: cgp_0535
CGJ: AR0_02810
CAMG: CAMM_01105
CSUR: N24_0594
CCYC: SCMU_39990
NFA: NFA_35030
NFR: ERS450000_00547(aldH)
ROP: ROP_36470
RHB: NY08_3285
GOR: KTR9_2911
SGR: SGR_1630
SMAL: SMALA_8024
ART: Arth_0036
ARR: ARUE_232p01560(aldH)
ACH: Achl_0350
IDO: I598_2355
PSIM: KR76_03115
NDA: Ndas_2498
SEN: SACE_0343
PSEE: FRP1_25195
ACTI: UA75_23150
ACAD: UA74_22630
AHG: AHOG_20555(aldH2)
HAU: Haur_2504
DFC: DFI_14760
OTE: Oter_2670
OBG: Verru16b_02510(aldH)
RBA: RB8941
PSL: Psta_0398
PIR: VN12_22435(aldH)
RUL: UC8_07880(aldH)
RML: FF011L_11250(aldH)
MFF: MFFC18_01570(aldH)
ROL: CA51_47380(aldH)
AHEL: Q31a_22560(aldH)
LCRE: Pla8534_61120(aldH)
AAGG: ETAA8_05840(aldH)
BVO: Pan97_46520(aldH)
RLC: K227x_12930(aldH)
PLM: Plim_1474
PEH: Spb1_22830(aldH)
PLS: VT03_00695(aldH)
FMR: Fuma_03966(aldH)
GMR: GmarT_34090(aldH)
GPN: Pan110_32220(aldH)
MRI: Mal4_21550(aldH)
SDYN: Mal52_00640(aldH)
PLON: Pla110_37110(aldH)
GES: VT84_29740(aldH)
ACA: ACP_2733(aldH)
CPI: Cpin_5585
SMIZ: 4412673_01388(aldH)
STHA: NCTC11429_00326(aldH)
MUC: MuYL_0982
SLI: Slin_1008
PSEZ: HME7025_01775(aldH)
LBY: Lbys_1775
FAE: FAES_4421(aldH)
GFL: GRFL_0581
ZPR: ZPR_1384
MARM: YQ22_13925
CBAL: M667_17525
CBAT: M666_17530
DDO: I597_0361
ZGA: ZOBELLIA_4011(aldH)
MLT: VC82_2607
WIN: WPG_1844
TMAR: MARIT_0673
MARF: CJ739_3132
FBU: UJ101_02217(aldH)
EAO: BD94_2187
ELB: VO54_00506(aldH)
CHZ: CHSO_2634(aldH)
CGLE: NCTC11432_00788(aldH)
 » show all
Reference
  Authors
Moore RA, Reckseidler-Zenteno S, Kim H, Nierman W, Yu Y, Tuanyok A, Warawa J, DeShazer D, Woods DE
  Title
Contribution of gene loss to the pathogenic evolution of Burkholderia pseudomallei and Burkholderia mallei.
  Journal
Infect Immun 72:4172-87 (2004)
DOI:10.1128/IAI.72.7.4172-4187.2004
Reference
  Authors
Watanabe S, Shimada N, Tajima K, Kodaki T, Makino K
  Title
Identification and characterization of L-arabonate dehydratase, L-2-keto-3-deoxyarabonate dehydratase, and L-arabinolactonase involved in an alternative pathway of L-arabinose metabolism. Novel evolutionary insight into sugar metabolism.
  Journal
J Biol Chem 281:33521-36 (2006)
DOI:10.1074/jbc.M606727200
Reference
  Authors
Aghaie A, Lechaplais C, Sirven P, Tricot S, Besnard-Gonnet M, Muselet D, de Berardinis V, Kreimeyer A, Gyapay G, Salanoubat M, Perret A
  Title
New insights into the alternative D-glucarate degradation pathway.
  Journal
J Biol Chem 283:15638-46 (2008)
DOI:10.1074/jbc.M800487200
  Sequence
[aci:ACIAD0131]
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