KEGG ORTHOLOGY: K13952

ORTHOLOGY: K13952

Entry

K13952                      KO

Symbol

ADH6

Name

alcohol dehydrogenase 6 [EC:1.1.1.1]

Pathway

map00010

Glycolysis / Gluconeogenesis

map00071

Fatty acid degradation

map00350

Tyrosine metabolism

map00620

Pyruvate metabolism

map00830

Retinol metabolism

map00980

Metabolism of xenobiotics by cytochrome P450

map00982

Drug metabolism - cytochrome P450

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

map04936

Alcoholic liver disease

Reaction

R00623

primary_alcohol:NAD+ oxidoreductase

R00754

ethanol:NAD+ oxidoreductase

R02124

retinol:NAD+ oxidoreductase

R04880

3,4-dihydroxyphenylethyleneglycol:NAD+ oxidoreductase

R07105

trichloroethanol:NAD+ oxidoreductase

R08281

alcophosphamide:NAD+ oxidoreductase

R08306

2-phenyl-1,3-propanediol monocarbamate:NAD+ oxidoreductase

R08310

4-hydroxy-5-phenyltetrahydro-1,3-oxazin-2-one:NAD+ oxidoreductase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09101 Carbohydrate metabolism
   00010 Glycolysis / Gluconeogenesis
    K13952  ADH6; alcohol dehydrogenase 6
   00620 Pyruvate metabolism
    K13952  ADH6; alcohol dehydrogenase 6
  09103 Lipid metabolism
   00071 Fatty acid degradation
    K13952  ADH6; alcohol dehydrogenase 6
  09105 Amino acid metabolism
   00350 Tyrosine metabolism
    K13952  ADH6; alcohol dehydrogenase 6
  09108 Metabolism of cofactors and vitamins
   00830 Retinol metabolism
    K13952  ADH6; alcohol dehydrogenase 6
  09111 Xenobiotics biodegradation and metabolism
   00980 Metabolism of xenobiotics by cytochrome P450
    K13952  ADH6; alcohol dehydrogenase 6
   00982 Drug metabolism - cytochrome P450
    K13952  ADH6; alcohol dehydrogenase 6
09160 Human Diseases
  09167 Endocrine and metabolic disease
   04936 Alcoholic liver disease
    K13952  ADH6; alcohol dehydrogenase 6
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.1  Acting on the CH-OH group of donors
   1.1.1  With NAD+ or NADP+ as acceptor
    1.1.1.1  alcohol dehydrogenase
     K13952  ADH6; alcohol dehydrogenase 6

Other DBs

GO:

0004022

Genes

HSA:

130(ADH6)

PTR:	461395(ADH6)

PPS:	100970400(ADH6)

GGO:	101134316(ADH6)

PON:	100173203(ADH6)

PPYG:

129035186(ADH6)

NLE:	100590814(ADH6)

HMH:	116456091(ADH6)

SSYN:

129492087(ADH6)

MCC:	707585(ADH6)

MCF:	102120901(ADH6)

MTHB:

126954778

MNI:	105486383(ADH6)

CSAB:

103236016(ADH6)

CATY:

105571348(ADH6)

PANU:

101014386(ADH6)

TGE:	112624743(ADH6)

MLEU:

105532364(ADH6)

RRO:	104657047(ADH6)

RBB:	108531878(ADH6)

TFN:	117084919(ADH6)

PTEH:

111525514(ADH6)

CIMI:

108294356

ANAN:

105732622

MCAL:

110290724

RNO:	310903(Adh6)

MCOC:

ANU:

ASYL:

MUN:

CGE:

MAUA:

PROB:

PLEU:

PMAV:

MORG:

MFOT:

AAMP:

CNL:

NGI:

OCU:

TUP:	102494070(ADH6)

GVR:

103597179

UMR:

103677923

UAH:	113263119(ADH6)

UAR:	123788778(ADH6)

LLV:

125093205

MPUF:

101689189

MNP:	132014067(ADH6)

MLK:

131819641

NVS:

122890457

ORO:

101368753

EJU:	114202912 114202915

ZCA:

MLX:

MANO:

NSU:

LWW:

BTA:	510551(ADH6)

BOM:	102284246(ADH6)

BIU:	109560320(ADH6)

BJV:

133249336

BBUB:

102407762(ADH6)

BKE:

129657160

BBIS:

104994660(ADH6)

CHX:	102177153 102183581

OAS:	114115282 114115283

OCAN:

BTAX:

CSUM:

ODA:

CCAD:

MREE:

OVR:

MBEZ:

CFR:	102523105(ADH6)

CBAI:

105067892

CDK:	105089541(ADH6)

VPC:	102529044(ADH6)

ECB:	111772843 111772844

EPZ:

103544018

EAI:	106827758 123283859

MYB:	102254104(ADH6)

MYD:	102752210(ADH6)

MMYO:

118671709

MLF:

102429627

MDT:	132216001(ADH6)

MYUM:

138993212

PKL:

118703718

EFUS:

103287827

POTS:

308236932(ADH6)

MNA:	107535676(ADH6)

DRO:	112317676(ADH6)

SHON:

118982186(ADH6)

AJM:	119061895(ADH6)

PDIC:

114492306(ADH6)

PHAS:

123806783(ADH6)

MMF:	118628872(ADH6)

PPAM:

129085335(ADH6)

HAI:	109392936(ADH6)

RFQ:	117022476(ADH6)

RAY:

LAV:

ETF:

Reference

PMID:1881901

Authors

Yasunami M, Chen CS, Yoshida A

Title

A human alcohol dehydrogenase gene (ADH6) encoding an additional class of isozyme.

Journal

Proc Natl Acad Sci U S A 88:7610-4 (1991)
DOI:10.1073/pnas.88.17.7610

Sequence

[hsa:130]

LinkDB

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