KEGG ORTHOLOGY: K14134

ORTHOLOGY: K14134

Entry

K14134                      KO

Symbol

FTMPT2

Name

12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase [EC:2.5.1.110]

Pathway

map00404

Staurosporine biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00786

Fumitremorgin alkaloid biosynthesis, tryptophan + proline => fumitremorgin C/A

Reaction

R10457

dimethylallyl-diphosphate:12alpha,13alpha-dihydroxyfumitremorgin C dimethylallyl-N-1-transferase

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K14134  FTMPT2; 12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01006 Prenyltransferases
    K14134  FTMPT2; 12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase
Enzymes [BR:ko01000]
2. Transferases
  2.5  Transferring alkyl or aryl groups, other than methyl groups
   2.5.1  Transferring alkyl or aryl groups, other than methyl groups (only sub-subclass identified to date)
    2.5.1.110  12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase
     K14134  FTMPT2; 12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase
Prenyltransferases [BR:ko01006]
Compound prenylation
  Indole prenyltransferase
   K14134  FTMPT2; 12alpha,13alpha-dihydroxyfumitremorgin C prenyltransferase

Genes

AFM:	AFUA_8G00250

NFI:	NFIA_093760

APUU:

APUU_22026S

Reference

PMID:18683158

Authors

Grundmann A, Kuznetsova T, Afiyatullov SSh, Li SM

Title

FtmPT2, an N-prenyltransferase from Aspergillus fumigatus, catalyses the last step in the biosynthesis of fumitremorgin B.

Journal

Chembiochem 9:2059-63 (2008)
DOI:10.1002/cbic.200800240

Sequence

[afm:AFUA_8G00250]

LinkDB

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