KEGG   ORTHOLOGY: K14139
Entry
K14139                      KO                                     
Symbol
IRGM, LRG47
Name
immunity-related GTPase family M protein [EC:3.6.5.-]
Pathway
map04621  NOD-like receptor signaling pathway
map05145  Toxoplasmosis
Disease
H00286  Crohn disease
H00342  Tuberculosis
H01227  Inflammatory bowel disease (IBD)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09150 Organismal Systems
  09151 Immune system
   04621 NOD-like receptor signaling pathway
    K14139  IRGM, LRG47; immunity-related GTPase family M protein
 09160 Human Diseases
  09174 Infectious disease: parasitic
   05145 Toxoplasmosis
    K14139  IRGM, LRG47; immunity-related GTPase family M protein
Enzymes [BR:ko01000]
 3. Hydrolases
  3.6  Acting on acid anhydrides
   3.6.5  Acting on GTP to facilitate cellular and subcellular movement
    3.6.5.-
     K14139  IRGM, LRG47; immunity-related GTPase family M protein
Genes
HSA: 345611(IRGM)
PTR: 471699(IRGM)
PPS: 100995835(IRGM)
GGO: 101131816(IRGM)
PON: 100450236(IRGM)
NLE: 100606227(IRGM)
MTHB: 126956093
MNI: 105466858(IRGM)
CSAB: 103245185(IRGM)
CATY: 105589937(IRGM)
TGE: 112626768(IRGM)
RRO: 104670438(IRGM)
RBB: 108532077(IRGM)
TFN: 117066106(IRGM)
PTEH: 111552610(IRGM)
CANG: 105504241(IRGM)
LCAT: 123638892(IRGM)
OGA: 100966078(IRGM)
MMU: 15944(Irgm1) 54396(Irgm2)
RNO: 100362733(Irgm2) 303090(Irgm)
MCOC: 116078615
HGL: 101707512(Irgm)
DORD: 105996765
DSP: 122115440
NCAR: 124987102
OCU: 100342275
OPI: 101536012(IRGM)
GVR: 103605288(IRGM)
MLX: 118010849 118011595(IRGM)
NSU: 110580274
LWW: 115939718
PYU: 121016631(IRGM)
PBG: 122471542(IRGM)
PTG: 102951860(IRGM)
PPAD: 109260635(IRGM)
AJU: 106969993
MJV: 108390689(IRGM)
LAV: 100667174(IRGM) 100669062
DNM: 101434951
 » show all
Reference
  Authors
Bekpen C, Hunn JP, Rohde C, Parvanova I, Guethlein L, Dunn DM, Glowalla E, Leptin M, Howard JC
  Title
The interferon-inducible p47 (IRG) GTPases in vertebrates: loss of the cell autonomous resistance mechanism in the human lineage.
  Journal
Genome Biol 6:R92 (2005)
DOI:10.1186/gb-2005-6-11-r92
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