KEGG   ORTHOLOGY: K14178
Entry
K14178            Tight     KO                                     
Symbol
AMS1
Name
amorpha-4,11-diene synthase [EC:4.2.3.24]
Pathway
map00909  Sesquiterpenoid and triterpenoid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R07630  2-trans,6-trans-farnesyl-diphosphate diphosphate-lyase (amorpha-4,11-diene-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K14178  AMS1; amorpha-4,11-diene synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.24  amorpha-4,11-diene synthase
     K14178  AMS1; amorpha-4,11-diene synthase
Other DBs
GO: 0034006
Genes
AG: AAF98444(AMS1)
Reference
  Authors
Wallaart TE, Bouwmeester HJ, Hille J, Poppinga L, Maijers NC
  Title
Amorpha-4,11-diene synthase: cloning and functional expression of a key enzyme in the biosynthetic pathway of the novel antimalarial drug artemisinin.
  Journal
Planta 212:460-5 (2001)
DOI:10.1007/s004250000428
  Sequence
LinkDB

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