KEGG ORTHOLOGY: K14208

ORTHOLOGY: K14208

Entry

K14208                      KO

Symbol

XPNPEP2

Name

Xaa-Pro aminopeptidase 2 [EC:3.4.11.9]

Pathway

map04974

Protein digestion and absorption

Brite

KEGG Orthology (KO) [BR:ko00001]
09150 Organismal Systems
  09154 Digestive system
   04974 Protein digestion and absorption
    K14208  XPNPEP2; Xaa-Pro aminopeptidase 2
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01002 Peptidases and inhibitors
    K14208  XPNPEP2; Xaa-Pro aminopeptidase 2
  09183 Protein families: signaling and cellular processes
   00537 Glycosylphosphatidylinositol (GPI)-anchored proteins
    K14208  XPNPEP2; Xaa-Pro aminopeptidase 2
Enzymes [BR:ko01000]
3. Hydrolases
  3.4  Acting on peptide bonds (peptidases)
   3.4.11  Aminopeptidases
    3.4.11.9  Xaa-Pro aminopeptidase
     K14208  XPNPEP2; Xaa-Pro aminopeptidase 2
Peptidases and inhibitors [BR:ko01002]
Metallo peptidases
  Family M24
   K14208  XPNPEP2; Xaa-Pro aminopeptidase 2
Glycosylphosphatidylinositol (GPI)-anchored proteins [BR:ko00537]
Enzymes
  K14208  XPNPEP2; Xaa-Pro aminopeptidase 2

Other DBs

GO:

0004177

Genes

HSA:	7512(XPNPEP2)

PTR:	465852(XPNPEP2)

PPS:	100988589(XPNPEP2)

GGO:	101147510(XPNPEP2)

PON:	100431631(XPNPEP2)

PPYG:

129025251(XPNPEP2)

NLE:	100605868(XPNPEP2)

HMH:	116811186(XPNPEP2)

SSYN:

129475818(XPNPEP2)

MCC:	701972(XPNPEP2)

MCF:	102144791(XPNPEP2)

MTHB:

126946781

MNI:	105468459(XPNPEP2)

CSAB:

103232537(XPNPEP2)

CATY:

105586277(XPNPEP2)

PANU:

101002120(XPNPEP2)

TGE:	112615866(XPNPEP2)

MLEU:

105545806(XPNPEP2)

RRO:	104655371(XPNPEP2)

RBB:	108515937(XPNPEP2)

TFN:	117077956(XPNPEP2)

PTEH:

111531555(XPNPEP2)

CANG:

105508157(XPNPEP2)

CJC:	100415713(XPNPEP2)

SBQ:	101039287(XPNPEP2)

CIMI:

108288527(XPNPEP2)

ANAN:

105721637(XPNPEP2)

CSYR:

103257661(XPNPEP2)

MMUR:

105863399(XPNPEP2)

LCAT:

123628337(XPNPEP2)

ERUF:

138378199(XPNPEP2)

PCOQ:

105817603(XPNPEP2)

OGA:	100965017(XPNPEP2)

MMU:	170745(Xpnpep2)

MCAL:

110286963(Xpnpep2)

MPAH:

110313657(Xpnpep2)

RNO:	117522(Xpnpep2)

MCOC:

116079917(Xpnpep2)

ANU:	117695374(Xpnpep2)

ASYL:

127675385(Xpnpep2)

MUN:	110565258(Xpnpep2)

CGE:	100774553(Xpnpep2)

MAUA:

101829988(Xpnpep2)

PROB:

127217475(Xpnpep2)

PLEU:

114705487(Xpnpep2)

PMAV:

102927191(Xpnpep2)

MORG:

121444832 121444900

MFOT:

126489631

AAMP:

119805201(Xpnpep2)

CNL:	130867729(Xpnpep2)

NGI:	103728748(Xpnpep2)

HGL:	101724021(Xpnpep2)

CPOC:

100732623(Xpnpep2)

CCAN:

109703425(Xpnpep2)

DORD:

105987003(Xpnpep2)

DSP:	122109930(Xpnpep2)

DMER:

138840074(Xpnpep2)

PLOP:

125343493(Xpnpep2)

NCAR:

124971917

MMMA:

107153022(Xpnpep2)

ITI:	101969165(Xpnpep2)

OCU:

100339097

OPI:	101520997(XPNPEP2)

OCZ:	121169233(XPNPEP2)

TUP:	102492698(XPNPEP2)

GVR:	103590202(XPNPEP2)

CFA:	492124(XPNPEP2)

CLUD:

112649307(XPNPEP2)

VVP:	112934647(XPNPEP2)

VLG:	121483372(XPNPEP2)

NPO:	129517534(XPNPEP2)

AML:	100473781(XPNPEP2)

UMR:	103667620(XPNPEP2)

UAH:	113270944(XPNPEP2)

UAR:	123789882(XPNPEP2)

ELK:

111157279

LLV:

125092108

MPUF:

101686002(XPNPEP2)

MNP:	132007740(XPNPEP2)

MLK:	131821692(XPNPEP2)

NVS:	122897189(XPNPEP2)

ORO:	101379805(XPNPEP2)

EJU:	114223756(XPNPEP2)

ZCA:	113930179(XPNPEP2)

MLX:	118011540(XPNPEP2)

NSU:	110576613(XPNPEP2)

LWW:

102727352

FCA:	101090244(XPNPEP2)

PYU:	121025536(XPNPEP2)

PCOO:

112870992(XPNPEP2)

PBG:	122478000(XPNPEP2)

PVIV:

125157205(XPNPEP2)

LRUF:

124514030

LGF:	123594109(XPNPEP2)

AJU:

106981600

PTG:	102955245(XPNPEP2)

PPAD:

109253767(XPNPEP2)

PUC:

125931394

HHV:	120244346(XPNPEP2)

BTA:	504822(XPNPEP2)

BOM:	102279235(XPNPEP2)

BIU:	109555450(XPNPEP2)

BBUB:

102411103(XPNPEP2)

BKE:	129638663(XPNPEP2)

CHX:	102174197 108634427

OAS:	101120054(XPNPEP2)

BTAX:

128070381(XPNPEP2)

CSUM:

138071384(XPNPEP2)

ODA:	120881478(XPNPEP2)

CCAD:

122435481(XPNPEP2)

MREE:

136154021(XPNPEP2)

OVR:	110134940(XPNPEP2)

MBEZ:

129564585(XPNPEP2)

SSC:	445538(XPNPEP2)

CFR:	102522517(XPNPEP2)

CBAI:

105079684(XPNPEP2)

CDK:	105098824(XPNPEP2)

VPC:	102543796(XPNPEP2)

BACU:

103014837(XPNPEP2)

BMUS:

118889254(XPNPEP2)

LVE:	103086605(XPNPEP2)

OOR:	101280430(XPNPEP2)

LALB:

132513272(XPNPEP2)

GMF:	115846274(XPNPEP2)

DDP:	132418932(XPNPEP2)

DLE:	111168015(XPNPEP2)

PCAD:

102991997(XPNPEP2)

PSIU:

116748094(XPNPEP2)

PPHC:

136142476(XPNPEP2)

NASI:

112409063(XPNPEP2)

ECB:	100059029(XPNPEP2)

EPZ:	103542648(XPNPEP2)

EAI:	106847096(XPNPEP2)

MYB:	102253402(XPNPEP2)

MYD:	102752137(XPNPEP2)

MMYO:

118654518(XPNPEP2)

MLF:	102430151(XPNPEP2)

MDT:	132224928(XPNPEP2)

PKL:	118721983(XPNPEP2)

EFUS:

103297215(XPNPEP2)

MNA:	107539447(XPNPEP2)

DRO:	112310835(XPNPEP2)

SHON:

118996091(XPNPEP2)

AJM:	119050666(XPNPEP2)

PDIC:

114505314(XPNPEP2)

PHAS:

123827836(XPNPEP2)

MMF:	118635848(XPNPEP2)

PPAM:

129073296(XPNPEP2)

HAI:	109388861(XPNPEP2)

RFQ:	117023395(XPNPEP2)

PALE:

102898601(XPNPEP2)

PGIG:

120604305(XPNPEP2)

PVP:	105308306(XPNPEP2)

RAY:	107514755(XPNPEP2)

MJV:	108399225(XPNPEP2)

TOD:	119245910(XPNPEP2)

SARA:

101558053(XPNPEP2)

SFUM:

130017013(XPNPEP2)

SETR:

125998668(XPNPEP2)

LAV:	100654893(XPNPEP2)

TMU:

101350653

ETF:	101643860(XPNPEP2)

DNM:	101439470(XPNPEP2)

MDO:	100021640(XPNPEP2)

GAS:	123253867(XPNPEP2)

SHR:	100917630(XPNPEP2)

AFZ:

127542489

PCW:	110196548(XPNPEP2)

TVP:	118832617(XPNPEP2)

PBRV:

138150647(XPNPEP2)

MLAO:

141496837(XPNPEP2)

OAA:	100093296(XPNPEP2)

TACU:

119929710(XPNPEP2)

GGA:	422137(XPNPEP2)

PCOC:

116229450(XPNPEP2)

MGP:	100543255(XPNPEP2)

CJO:	107312536(XPNPEP2)

TPAI:

128075888(XPNPEP2)

LMUT:

125699614(XPNPEP2)

NMEL:

110403263(XPNPEP2)

APLA:

101801782(XPNPEP2)

AACU:

137863887(XPNPEP2)

ACYG:

106037639(XPNPEP2)

CATA:

118245438(XPNPEP2)

AFUL:

116494488(XPNPEP2)

TGU:	100232340(XPNPEP2)

LSR:	110480090(XPNPEP2)

SCAN:

103816477(XPNPEP2)

PMOA:

120512635(XPNPEP2)

OTC:	121346461(XPNPEP2)

PRUF:

121362773(XPNPEP2)

ATRC:

139597115(XPNPEP2)

GFR:	102033233(XPNPEP2)

FAB:	101820999(XPNPEP2)

OMA:	130252941(XPNPEP2)

PHI:	102105320(XPNPEP2)

PMAJ:

107203669(XPNPEP2)

CCW:	104691693(XPNPEP2)

CBRC:

103622233(XPNPEP2)

ACOE:

138110641(XPNPEP2)

ETL:	114064646(XPNPEP2)

ZAB:	102062195(XPNPEP2)

ZLE:	135447825(XPNPEP2)

ACHL:

103801485(XPNPEP2)

SVG:	106862173(XPNPEP2)

MMEA:

130578717(XPNPEP2)

HRT:	120761931(XPNPEP2)

SATI:

136370429(XPNPEP2)

CCIC:

134050060(XPNPEP2)

FPG:	101911277(XPNPEP2)

FCH:	102050844(XPNPEP2)

SHAB:

115613304(XPNPEP2)

ACUN:

113480171(XPNPEP2)

TALA:

116963422(XPNPEP2)

ACHC:

115333744(XPNPEP2)

HLE:	104831498(XPNPEP2)

AGEN:

126050399

HHAR:

128153790(XPNPEP2)

BBUT:

142043056(XPNPEP2)

DPUB:

104307210(XPNPEP2)

PPUS:

135183916(XPNPEP2)

NNI:	104012638(XPNPEP2)

PARX:

142063069(XPNPEP2)

AFOR:

103903418(XPNPEP2)

CBOR:

142087925(XPNPEP2)

CBOY:

140658648(XPNPEP2)

MAME:

142415055(XPNPEP2)

CLV:	102086340(XPNPEP2)

CNIC:

135993512(XPNPEP2)

CUCA:

104060512(XPNPEP2)

CPEA:

104393937(XPNPEP2)

RTD:	128914608(XPNPEP2)

CRID:

134520601(XPNPEP2)

LMIC:

141748386(XPNPEP2)

NARQ:

141464650(XPNPEP2)

AAM:	106484106(XPNPEP2)

AROW:

112969167(XPNPEP2)

NPD:	112946992(XPNPEP2)

TGT:	104574585(XPNPEP2)

DNE:	112990882(XPNPEP2)

SCAM:

104142867(XPNPEP2)

ASN:	102384297(XPNPEP2)

AMJ:	102570935(XPNPEP2)

CPOO:

109310919(XPNPEP2)

GGN:	109300502(XPNPEP2)

PSS:	102459644(XPNPEP2)

CIZ:	142020097(XPNPEP2)

CMY:	102939220(XPNPEP2)

CCAY:

125643130(XPNPEP2)

LKP:	140917545(XPNPEP2)

NDS:	141993520(XPNPEP2)

CPIC:

101938524(XPNPEP2)

CABI:

116820971(XPNPEP2)

MRV:	120372020(XPNPEP2)

ACS:	100563559(xpnpep2)

ASAO:

132763015(XPNPEP2)

PVT:	110084941(XPNPEP2)

SUND:

121936653(XPNPEP2)

PBI:	103057561(XPNPEP2)

PMUR:

107291560(XPNPEP2)

CTIG:

120302521(XPNPEP2)

PGUT:

117669509(XPNPEP2)

PCAE:

139322766(XPNPEP2)

APRI:

131183913(XPNPEP2)

PTEX:

113437817(XPNPEP2)

NSS:	113416704(XPNPEP2)

VKO:	123022123(XPNPEP2)

PMUA:

114588938(XPNPEP2)

PRAF:

128406284(XPNPEP2)

ZVI:	118084050(XPNPEP2)

HCG:	128335349(XPNPEP2)

GJA:	107106070(XPNPEP2)

STOW:

125443168(XPNPEP2)

EMC:	129341677(XPNPEP2)

XLA:	431877(xpnpep2.L) 446303(xpnpep2.S)

XTR:	100145559(xpnpep2)

NPR:	108792996(XPNPEP2) 108792997

RTEM:

120914370 120914630

ACAT:

141107400 141107401

PADS:

140343035(XPNPEP2) 140343783

BBUF:

120977538(XPNPEP2)

BGAR:

122919774(XPNPEP2)

DTC:	141101053(XPNPEP2)

PWL:	138265327(XPNPEP2)

MUO:	115474362(XPNPEP2)

GSH:	117361169(XPNPEP2)

DRE:	394007(xpnpep2)

SRX:	107744566 107752061

SANH:

107658016 107664313

SGH:	107550741 107561458

CCAR:

109060320 109102732

CAUA:

113113921(xpnpep2)

CGIB:

127971934

PTET:

122358151(xpnpep2)

LROH:

127175920(xpnpep2)

OMC:	131552935(xpnpep2)

PPRM:

120474389(xpnpep2)

RKG:	130090923(xpnpep2)

MAMB:

125258759(xpnpep2)

CIDE:

127494485

CERY:

137012478(xpnpep2)

MASI:

127412561 127417690

TROS:

130563527(xpnpep2)

TDW:	130438042(xpnpep2)

MANU:

129422454(xpnpep2)

PDAB:

135757301(xpnpep2)

IPU:

108268524

IFU:	128611813(xpnpep2)

PHYP:

113529118(xpnpep2)

SMEO:

124386091(xpnpep2)

TFD:	113636138(xpnpep2)

TVC:	132856088(xpnpep2)

CGAR:

128531296(xpnpep2)

NGRA:

132889903(xpnpep2)

TRN:	134318896(xpnpep2)

AMEX:

103027325(xpnpep2)

CMAO:

118807148(xpnpep2)

EEE:	113582651(xpnpep2)

CHAR:

105893013(xpnpep2)

SPIL:

134068785(xpnpep2)

ASAD:

121694844(xpnpep2)

TRU:	101073078(xpnpep2)

TFS:	130531120(xpnpep2)

TNG:	GSTEN00011366G001

LCO:	104928722(xpnpep2)

NCC:	104945922(xpnpep2)

TBEN:

117489280(xpnpep2)

CGOB:

115014390(xpnpep2)

PGEO:

117453694(xpnpep2)

GACU:

117543475(xpnpep2)

EMAC:

134860358(xpnpep2)

ELY:	117260578(xpnpep2)

EFO:	125893988(xpnpep2)

PLEP:

121948238(xpnpep2)

SLUC:

116052378(xpnpep2)

ECRA:

117951341(xpnpep2)

ESP:	116696718(xpnpep2)

PFLV:

114562669(xpnpep2)

GAT:	120817853(xpnpep2)

PPUG:

119211502(xpnpep2)

AFB:	129090220(xpnpep2)

CLUM:

117737586(xpnpep2)

PSWI:

130209611(xpnpep2)

CANA:

137794723(xpnpep2)

CVE:	137875648(xpnpep2)

MSAM:

119889210(xpnpep2)

SCHU:

122880207(xpnpep2)

EARM:

139291325(xpnpep2)

CUD:	121515877(xpnpep2)

SPUL:

138598453(xpnpep2)

LMIX:

132982136(xpnpep2)

HTC:	141793436(xpnpep2)

ALAT:

119007991(xpnpep2)

ASTR:

137602870(xpnpep2)

PKLU:

139206934(xpnpep2)

MZE:	101479687(xpnpep2)

ONL:	100691265(xpnpep2)

OAU:	116317614(xpnpep2)

OLA:	101162610(xpnpep2)

OML:	112153671(xpnpep2)

CSAI:

133447161(xpnpep2)

XMA:	102228194(xpnpep2)

XCO:	114139714(xpnpep2)

XHE:	116714858(xpnpep2)

PRET:

103471567(xpnpep2)

PFOR:

103150184(xpnpep2)

PLAI:

106945451(xpnpep2)

PMEI:

106915288(xpnpep2)

GAF:	122837500(xpnpep2)

PPRL:

129360299 129360792(xpnpep2)

CVG:	107093453(xpnpep2)

CTUL:

119786242(xpnpep2)

GMU:	124860916(xpnpep2)

NFU:	107377898(xpnpep2)

KMR:	108231166(xpnpep2)

ALIM:

106514801(xpnpep2)

NWH:	119408873(xpnpep2)

AOCE:

111582105(xpnpep2)

EJA:	138211718(xpnpep2)

BFRE:

138618518(xpnpep2)

MCEP:

125008667(xpnpep2)

CSEM:

103390529(xpnpep2)

POV:	109624141(xpnpep2)

SSEN:

122778094(xpnpep2)

SSOE:

131472336(xpnpep2)

HHIP:

117769312(xpnpep2)

HSP:	118112296(xpnpep2)

PPLT:

128446141(xpnpep2)

SMAU:

118319739(xpnpep2)

LCF:

108895418

SDU:	111232394(xpnpep2)

SLAL:

111648326(xpnpep2)

XGL:	120785412(xpnpep2)

HCQ:	109524276(xpnpep2)

SSCV:

125993586(xpnpep2)

SBIA:

133508310(xpnpep2)

PEE:	133408153(xpnpep2)

PTAO:

133485024(xpnpep2)

BPEC:

110158985(xpnpep2)

ENY:	140350955(xpnpep2)

MALB:

109956041(xpnpep2)

BSPL:

114864627(xpnpep2)

SJO:	128362901(xpnpep2)

SSCO:

133986403(xpnpep2)

TTY:	137189663(xpnpep2)

GMH:	115552652(xpnpep2)

SASA:

106611530(xpnpep2)

STRU:

115205079(xpnpep2)

OTW:	112256366(xpnpep2)

OMY:	110505163(xpnpep2)

OGO:	124011148(xpnpep2)

ONE:	115129575(xpnpep2)

OKI:	109905303(xpnpep2)

OKE:	118363621(xpnpep2)

OMM:	135546010(xpnpep2)

OCLA:

139390946

SALP:

111967609(xpnpep2)

SNH:	120062231(xpnpep2)

SFON:

129828001(xpnpep2)

CCLU:

121535209(xpnpep2)

ELS:	105008408(xpnpep2)

OEP:	134032943(xpnpep2)

SFM:	108922937(xpnpep2)

PKI:	111855460(xpnpep2)

AANG:

118222616(xpnpep2)

AROT:

135251643(xpnpep2)

CCOG:

133124944(xpnpep2)

LOC:	102686474(xpnpep2)

PSPA:

121318821(xpnpep2)

ARUT:

117430177 117962840(xpnpep2)

PSEX:

120537256(xpnpep2)

LCM:	102363021(XPNPEP2)

CMK:	103177536(xpnpep2)

RTP:	109914427(xpnpep2)

CPLA:

122557222(xpnpep2)

CPUN:

140495869(xpnpep2)

HOC:	132820257(xpnpep2)

SCAU:

119952364(xpnpep2)

LERI:

129702140(xpnpep2)

HAKA:

140734376(xpnpep2)

PMRN:

116955161(XPNPEP2)

LRJ:	133358766(XPNPEP2)

CIN:

SCLV:

CLEP:

APLC:

ARUN:

AAMU:

AFIL:

140141521 140141568 140141574

AJC:

LBD:

CCIN:

TCA:

TMOL:

ESIM:

EFOR:

RFG:

HAXR:

DCI:	103506457 103509545

MQU:	128989504 128990367

FOC:

TPAL:

ZNE:

CSEC:

PPOI:

GAE:

CRG:

CVN:	111126074 111127436

OED:

125679619

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Reference

PMID:8870669

Authors

Hyde RJ, Hooper NM, Turner AJ

Title

Molecular cloning and expression in COS-1 cells of pig kidney aminopeptidase P.

Journal

Biochem J 319 ( Pt 1):197-201 (1996)
DOI:10.1042/bj3190197

Sequence

[ssc:445538]

Reference

PMID:15708373

Authors

Ersahin C, Szpaderska AM, Orawski AT, Simmons WH

Title

Aminopeptidase P isozyme expression in human tissues and peripheral blood mononuclear cell fractions.

Journal

Arch Biochem Biophys 435:303-10 (2005)
DOI:10.1016/j.abb.2004.12.023

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