KEGG ORTHOLOGY: K14424

ORTHOLOGY: K14424

Entry

K14424                      KO

Symbol

SMO2

Name

plant 4alpha-monomethylsterol monooxygenase [EC:1.14.18.11]

Pathway

map00100

Steroid biosynthesis

map01100

Metabolic pathways

map01110

Biosynthesis of secondary metabolites

Module

M00917

Phytosterol biosynthesis, squalene 2,3-epoxide => campesterol/sitosterol

Reaction

R12378

24-methylenelophenol,ferrocytochrome-b5:oxygen oxidoreductase (C-4alpha-methyl-hydroxylating)

R12379

24-ethylidenelophenol,ferrocytochrome-b5:oxygen oxidoreductase (C-4alpha-methyl-hydroxylating)

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09103 Lipid metabolism
   00100 Steroid biosynthesis
    K14424  SMO2; plant 4alpha-monomethylsterol monooxygenase
Enzymes [BR:ko01000]
1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.18  With another compound as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.18.11  plant 4alpha-monomethylsterol monooxygenase
     K14424  SMO2; plant 4alpha-monomethylsterol monooxygenase

Genes

BCOO:

CCIN:

OTU:

PRAP:

OFU:

DCI:	103512287 103512289

ATH:	AT1G07420(SMO2-1) AT2G29390(SMO2-2)

ALY:	9315281 9325711

CRB:	17887780 17900058

CSAT:

104700565 104739310 104749943 104754908 104778598 104786746

EUS:	EUTSA_v10008485mg EUTSA_v10017113mg

BRP:	103836444 103843947 103864965

BNA:	106362242 106391117 106402219 106420038 106450049 106450054 111208485

BOE:	106307917 106310476 106336604 106344016

RSZ:	108813689 108819536 108848436 108859993 130506284 130509714

THJ:	104815774 104826306

CPAP:

110812189

CIT:

102611328

CIC:	CICLE_v10029052mg

PVY:

116144931

MINC:

123208340 123224689

TCC:

18590619

GRA:	105782837 105788785

GHI:	107934820 107944828 107950248 107950322

GAB:	108480542 108486460

HSYR:

120142165 120143299 120160068 120162099 120199310

DZI:	111302145 111303661

EGR:

104422462

RARG:

115736566

GMX:	100790183 100816716

GSJ:	114379876 114410260

PVU:	137810658 137810662

VRA:	106755866 106776423

VAR:	108323132 108323139

VUN:	114170147 114173059

VUM:	124827607 124843154

CCAJ:

109801255 109801590

APRC:

113868623 113868923

MTR:	11407532 11410003 120575921 25496266

TPRA:

123895575 123898285 123906764

CAM:	101502074 101515062

PSAT:

127119377

VVO:

131651052

LJA:	130739962 130739964

ADU:	107481295 107488889

AIP:	107631446 107643518

AHF:	112733956 112750064 112791831 112801082

LANG:

109330605 109331516 109332428

PCIN:

129313697 129315857

QSA:	O6P43_000166 O6P43_028181

FVE:

AANS:

RCN:

PPER:

PMUM:

PAVI:

PDUL:

MDM:	103423556 103447498

MSYL:

126591318 126616813

PXB:	103954259 103964715

PCOX:

ZJU:

MNT:

CSAV:

CSV:	101220009 116403756

CMO:

BHJ:

MCHA:

CMAX:

CMOS:

CPEP:

111782737 111784635 111785325 111786943 111787435

RCU:

8284099

MEAN:

126688239

HBR:	110636927 110636928 110644392

MESC:

110606641 110619585

POP:	7481517 7485682

PEU:	105131124 105133116

PALZ:

118033002 118058014

PNZ:	133680349 133685824

JRE:	108995763 108998492

CILL:

CAVE:

AGLU:

QSU:

QLO:

TWL:	119990517 120015759

VVI:	100242817 100260328

VRI:	117916804 117927889 117932035

SLY:	100736533 101258266(SMO4)

SPEN:

107023487 107023820

SOT:	102589817 102602168

SSTN:

SDUL:

CANN:

LBB:

NTA:	107784901 107791166 107795609 107803664

NSY:	104232522 104249758

NTO:	104108313 104113382

NAU:	109214178 109227039

INI:	109156240 109157995 109166491

ITR:	116017168 116024961

SIND:

105170642

OEU:	111369663 111374734

EGT:

SSPL:

SMIL:

SHIS:

APAN:

HPUM:

PHUA:

PEBU:

HAN:	110868287 110873890

ECAD:

122581549 122607629

LSV:	111907260 111907489

CCAV:

112512724 112518020

DCR:	108206447 108206900

CSIN:

114274145 114286899

RVL:	131314156 131316746

AEW:	130761028 130790545

DLT:	127798157 127808822

BVG:

104900049

SOE:

110787672

CQI:	110683366 110688354

ATRI:

130814075

MOF:

131147618

NNU:	104597106 104601110

MING:

122058151 122073165

TSS:	122651833 122671597

PSOM:

113298854 113313160

OSA:	4342171 4351226

DOSA:

Os07g0101500 Os11g0707600

OBR:	102706395 102708758

OGL:	127755528 127779539

BDI:

100835573

ATS:

109757775

TDC:	119286129 119295701

TAES:

123086313 123091749 123096733

TUA:

LPER:

LRD:

SBI:

ZMA:	100281761 542766

MFLO:

136449871 136508718 136535752 136540708

SITA:

101758336 101761504

SVS:	117856747 117866461

PVIR:

120645322 120673040 120685455 120707392

PHAI:

112895638 112903000

PAUA:

133886571 133900767

TANG:

140761756 140765494 140776032

PDA:	103697377 103715683 103716756

EGU:	105044346 105046366 105052184 105056895

MUS:	103969297 135613426 135616988 135622424

ZOF:	122013056 122015262 122042988 122047500

DCT:

110099264

PEQ:

110021891

AOF:	109822179 109848520

MSIN:

ACAK:

NCOL:

ATR:

CJF:

SMO:	SELMODRAFT_151304 SELMODRAFT_173304 SELMODRAFT_231600 SELMODRAFT_233175

PPP:	112285210 112288272

CME:	CYME_CMM277C

GSL:	Gasu_60480

CCP:	CHC_T00010320001

DDI:	DDB_G0279611

DPP:	DICPUDRAFT_28679 DICPUDRAFT_42415 DICPUDRAFT_76018 DICPUDRAFT_80876

DFA:

DFA_11723

ACAN:

ACA1_360510

NGR:	NAEGRDRAFT_61038

PSYC:

DABAL43B_2672

SOK:	D0B54_23595

AGE:	AA314_00718

AVM:	JQX13_12580

MBD:	MEBOL_003525

CFUS:

CYFUS_000150

» show all

Reference

PMID:11707264

Authors

Darnet S, Bard M, Rahier A

Title

Functional identification of sterol-4alpha-methyl oxidase cDNAs from Arabidopsis thaliana by complementation of a yeast erg25 mutant lacking sterol-4alpha-methyl oxidation.

Journal

FEBS Lett 508:39-43 (2001)
DOI:10.1016/S0014-5793(01)03002-2

Sequence

[ath:AT1G07420 AT2G29390]

Reference

PMID:21147141

Authors

Rahier A

Title

Dissecting the sterol C-4 demethylation process in higher plants. From structures and genes to catalytic mechanism.

Journal

Steroids 76:340-52 (2011)
DOI:10.1016/j.steroids.2010.11.011

LinkDB

DBGET integrated database retrieval system