KEGG   ORTHOLOGY: K14630
Entry
K14630                      KO                                     
Symbol
actVA5
Name
two-component flavin-dependent monooxygenase [EC:1.14.14.-]
Pathway
map01057  Biosynthesis of type II polyketide products
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00779  Dihydrokalafungin biosynthesis, octaketide => dihydrokalafungin
Reaction
R09313  dihydrokalafungin-dihydroquinone,FMNH2:oxygen oxidoreductase (hydroxylating)
R09314  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K14630  actVA5; two-component flavin-dependent monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K14630  actVA5; two-component flavin-dependent monooxygenase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Oxygenase
   K14630  actVA5; two-component flavin-dependent monooxygenase
Genes
PRUE: LVJ94_41795
SCO: SCO5080(SCBAC28G1.06)
SGRF: SGFS_016130
SDV: BN159_2499
SLV: SLIV_12985
SVT: SVTN_18835
SPHW: NFX46_12215
SCYA: EJ357_29930
SRK: FGW37_16310
SBRO: GQF42_04675
STPB: QR97_37450
TFU: Tfu_1234
CAI: Caci_6489
 » show all
Reference
  Authors
Valton J, Filisetti L, Fontecave M, Niviere V
  Title
A two-component flavin-dependent monooxygenase involved in actinorhodin biosynthesis in Streptomyces coelicolor.
  Journal
J Biol Chem 279:44362-9 (2004)
DOI:10.1074/jbc.M407722200
Reference
  Authors
Valton J, Fontecave M, Douki T, Kendrew SG, Niviere V
  Title
An aromatic hydroxylation reaction catalyzed by a two-component FMN-dependent Monooxygenase. The ActVA-ActVB system from Streptomyces coelicolor.
  Journal
J Biol Chem 281:27-35 (2006)
DOI:10.1074/jbc.M506146200
Reference
  Authors
Ellis HR
  Title
The FMN-dependent two-component monooxygenase systems.
  Journal
Arch Biochem Biophys 497:1-12 (2010)
DOI:10.1016/j.abb.2010.02.007
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