KEGG ORTHOLOGY: K14714

ORTHOLOGY: K14714

Entry

K14714                      KO

Symbol

SLC39A8, ZIP8

Name

solute carrier family 39 (zinc transporter), member 8

Pathway

map04216

Ferroptosis

map05010

Alzheimer disease

map05012

Parkinson disease

Disease

H00119

Congenital disorders of glycosylation type II

Brite

KEGG Orthology (KO) [BR:ko00001]
09140 Cellular Processes
  09143 Cell growth and death
   04216 Ferroptosis
    K14714  SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
09160 Human Diseases
  09164 Neurodegenerative disease
   05010 Alzheimer disease
    K14714  SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
   05012 Parkinson disease
    K14714  SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   02000 Transporters
    K14714  SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8
Transporters [BR:ko02000]
Solute carrier family (SLC)
  SLC39: Metal ion transporter
   K14714  SLC39A8, ZIP8; solute carrier family 39 (zinc transporter), member 8

Other DBs

GO:

0005385

TC:	2.A.5.4.8 2.A.5.4.15

Genes

HSA:	64116(SLC39A8)

PTR:	461405(SLC39A8)

PPS:	100978566(SLC39A8)

GGO:	101147092(SLC39A8)

PON:	100171966(SLC39A8)

PPYG:

129035461(SLC39A8)

NLE:	100582544(SLC39A8)

HMH:	116483634(SLC39A8)

SSYN:

129492059(SLC39A8)

MCC:	710142(SLC39A8)

MCF:	102137377(SLC39A8)

MTHB:

126955397

MNI:	105486343(SLC39A8)

CSAB:

103236046(SLC39A8)

CATY:

105571367(SLC39A8)

PANU:

101026422(SLC39A8)

TGE:	112624978(SLC39A8)

MLEU:

105548313(SLC39A8)

RRO:	104662314(SLC39A8)

RBB:	108532819(SLC39A8)

TFN:	117085709(SLC39A8)

PTEH:

111547970(SLC39A8)

CANG:

105512674(SLC39A8)

CJC:	100385303(SLC39A8)

SBQ:	101035154(SLC39A8)

CIMI:

108289256(SLC39A8)

ANAN:

105706301(SLC39A8)

CSYR:

103263590(SLC39A8)

MMUR:

105874823(SLC39A8)

LCAT:

123627205(SLC39A8)

PCOQ:

105819192(SLC39A8)

OGA:	100950746(SLC39A8)

MMU:	67547(Slc39a8)

MCAL:

110290845(Slc39a8)

MPAH:

110320285(Slc39a8)

RNO:	295455(Slc39a8)

MCOC:

116093826(Slc39a8)

ANU:	117707812(Slc39a8)

ASYL:

127682657(Slc39a8)

MUN:	110562611(Slc39a8)

CGE:	100767442(Slc39a8)

MAUA:

101839232(Slc39a8)

PROB:

127222972(Slc39a8)

PLEU:

114683212(Slc39a8)

PMAV:

102922201(Slc39a8)

MORG:

121451231(Slc39a8)

MFOT:

126503577

AAMP:

119800853(Slc39a8)

NGI:	103728035(Slc39a8)

HGL:	101713325(Slc39a8)

CCAN:

109675700(Slc39a8)

DORD:

105991224(Slc39a8)

DSP:	122127194(Slc39a8)

DMER:

138826948(Slc39a8)

PLOP:

125341408(Slc39a8)

NCAR:

124994791

MMMA:

107141350(Slc39a8)

ITI:	101973058(Slc39a8)

OCU:

100351178

OPI:	101531834(SLC39A8)

OCZ:	121147422(SLC39A8)

TUP:	102502956(SLC39A8)

GVR:	103597142(SLC39A8)

CFA:	478494(SLC39A8)

CLUD:

112644603(SLC39A8)

VVP:	112908379(SLC39A8)

VLG:	121493267(SLC39A8)

NPO:	129521209(SLC39A8)

AML:	100470583(SLC39A8)

UMR:	103677987(SLC39A8)

UAH:	113263102(SLC39A8)

UAR:	123788892(SLC39A8)

ELK:

111156218

LLV:

125093223

MPUF:

101681774(SLC39A8)

MNP:	132001740(SLC39A8)

MLK:	131829882(SLC39A8)

NVS:	122889332(SLC39A8)

ORO:	101370996(SLC39A8)

EJU:	114199325(SLC39A8)

ZCA:	113924769(SLC39A8)

MLX:	118027046(SLC39A8)

NSU:	110572157(SLC39A8)

LWW:	102738324(SLC39A8)

FCA:	101096887(SLC39A8)

PYU:	121031906(SLC39A8)

PCOO:

112858291(SLC39A8)

PBG:	122478022(SLC39A8)

PVIV:

125164402(SLC39A8)

LRUF:

124520368

LGF:	123594779(SLC39A8)

AJU:

106984698

PTG:	102951767(SLC39A8)

PPAD:

109247369(SLC39A8)

PUC:

125923692

PLEZ:

122218005(SLC39A8)

HHV:	120223986(SLC39A8)

BTA:	508193(SLC39A8)

BOM:	102287443(SLC39A8)

BIU:	109560298(SLC39A8)

BBUB:

102413959(SLC39A8)

BBIS:

104994640(SLC39A8)

CHX:	102182487(SLC39A8)

OAS:	101108488(SLC39A8)

BTAX:

128049866(SLC39A8)

CSUM:

138081977(SLC39A8)

ODA:	120861875(SLC39A8)

CCAD:

122422326(SLC39A8)

MREE:

136148015(SLC39A8)

OVR:	110142659(SLC39A8)

MBEZ:

129561519(SLC39A8)

SSC:	100524695(SLC39A8)

CFR:	102505646(SLC39A8)

CBAI:

105067910(SLC39A8)

CDK:	105089557(SLC39A8)

VPC:	102532421(SLC39A8)

BACU:

103004766(SLC39A8)

BMUS:

118895769(SLC39A8)

LVE:	103068373(SLC39A8)

OOR:	101279349(SLC39A8)

LALB:

132519195(SLC39A8)

GMF:	115846434(SLC39A8)

DDP:	132425769(SLC39A8)

DLE:	111179109(SLC39A8)

PCAD:

102994939(SLC39A8)

PSIU:

116754651(SLC39A8)

PPHC:

136123560(SLC39A8)

NASI:

112393806(SLC39A8)

ECB:	100067821(SLC39A8)

EPZ:	103556718(SLC39A8)

EAI:	106825954(SLC39A8)

MYB:	102255760(SLC39A8)

MYD:	102754372(SLC39A8)

MMYO:

118671864(SLC39A8)

MLF:	102435441(SLC39A8)

MDT:	132215724(SLC39A8)

MYUM:

138992990(SLC39A8)

PKL:	118703480(SLC39A8)

EFUS:

103299787(SLC39A8)

MNA:	107545486(SLC39A8)

DRO:	112317859(SLC39A8)

SHON:

118979967(SLC39A8)

AJM:	119057925(SLC39A8)

PDIC:

114492554(SLC39A8)

PHAS:

123806805(SLC39A8)

MMF:	118630485(SLC39A8)

PPAM:

129085323(SLC39A8)

RFQ:	117022606(SLC39A8)

PALE:

102880280(SLC39A8)

PGIG:

120591104(SLC39A8)

PVP:	105293030(SLC39A8)

RAY:	107517910(SLC39A8)

MJV:	108391708(SLC39A8)

TOD:	119243682(SLC39A8)

SARA:

101549314(SLC39A8)

SFUM:

130023571(SLC39A8)

SETR:

126027543(SLC39A8)

LAV:	100674152(SLC39A8)

TMU:

101351603

ETF:	101640265(SLC39A8)

DNM:	101429392(SLC39A8)

MDO:	100014598(SLC39A8)

GAS:	123253071(SLC39A8)

SHR:	100917883(SLC39A8)

AFZ:

127540751

PCW:	110209685(SLC39A8)

TVP:	118854042(SLC39A8)

PBRV:

138165648(SLC39A8)

MLAO:

141517301(SLC39A8)

OAA:	100073920(SLC39A8)

TACU:

119947613(SLC39A8)

GGA:	430411(SLC39A8)

PCOC:

116238889(SLC39A8)

MGP:	100547628(SLC39A8)

CJO:	107313654(SLC39A8)

TPAI:

128079891(SLC39A8)

LMUT:

125691712(SLC39A8)

NMEL:

110398429(SLC39A8)

APLA:

101802996(SLC39A8)

ACYG:

106045307(SLC39A8)

CATA:

118244661(SLC39A8)

AFUL:

116488549(SLC39A8)

TGU:	100217712(SLC39A8)

LSR:	110471150(SLC39A8)

SCAN:

103826266(SLC39A8)

PMOA:

120498832(SLC39A8)

OTC:	121346588(SLC39A8)

PRUF:

121362605(SLC39A8)

ATRC:

139592255(SLC39A8)

GFR:	102036794(SLC39A8)

FAB:	101815328(SLC39A8)

OMA:	130252803(SLC39A8)

PHI:	102110184(SLC39A8)

PMAJ:

107203510(SLC39A8)

CCAE:

111928327(SLC39A8)

CCW:	104697285(SLC39A8)

CBRC:

103617380(SLC39A8)

ACOE:

138108995(SLC39A8)

ETL:	114068167(SLC39A8)

ZAB:	102062109(SLC39A8)

ZLE:	135447343(SLC39A8)

ACHL:

103805345(SLC39A8)

SVG:	106852546(SLC39A8)

MMEA:

130584264(SLC39A8)

HRT:	120752933(SLC39A8)

SATI:

136360544(SLC39A8)

CCIC:

134044555(SLC39A8)

FPG:	101920184(SLC39A8)

FCH:	102049637(SLC39A8)

CCRI:

104167199(SLC39A8)

NNT:	104409181(SLC39A8)

SHAB:

115610514(SLC39A8)

ACUN:

113479680(SLC39A8)

TALA:

104355514(SLC39A8)

ACHC:

115341554(SLC39A8)

HALD:

104322969(SLC39A8)

HLE:	104827794(SLC39A8)

AGEN:

126044908

HHAR:

128136244(SLC39A8)

GCL:

127016076

CSTI:

104562360(SLC39A8)

LDI:	104339836(SLC39A8)

MNB:	103774242(SLC39A8)

DPUB:

104307771(SLC39A8)

PPUS:

135177984(SLC39A8)

AVIT:

104274564(SLC39A8)

BRHI:

104496099(SLC39A8)

EGZ:	104122597(SLC39A8)

NNI:	104021324(SLC39A8)

PCRI:

104023887(SLC39A8)

PCAO:

104042642(SLC39A8)

PADL:

103919559(SLC39A8)

AFOR:

103894278(SLC39A8)

FGA:	104075249(SLC39A8)

CBOR:

142082061(SLC39A8)

GSTE:

104261258(SLC39A8)

CBOY:

140652405(SLC39A8)

MAME:

142409306(SLC39A8)

CLV:	102086264(SLC39A8)

CNIC:

135988331(SLC39A8)

MUI:	104545058(SLC39A8)

PGUU:

104457538(SLC39A8)

PLET:

104625258(SLC39A8)

EHS:	104512959(SLC39A8)

CUCA:

104068738(SLC39A8)

TEO:	104373025(SLC39A8)

BREG:

104643373(SLC39A8)

OHA:	104331713(SLC39A8)

ACAR:

104526337(SLC39A8)

CPEA:

104393665(SLC39A8)

CVF:	104286884(SLC39A8)

RTD:	128910503(SLC39A8)

CRID:

134516320(SLC39A8)

LMIC:

141744132(SLC39A8)

AAM:	106491828(SLC39A8)

AROW:

112972223(SLC39A8)

NPD:	112957308(SLC39A8)

TGT:	104569605(SLC39A8)

DNE:	112988643(SLC39A8)

SCAM:

104153442(SLC39A8)

ASN:	102370497(SLC39A8)

AMJ:	102566753(SLC39A8)

CPOO:

109321862(SLC39A8)

GGN:	109303667(SLC39A8)

PSS:	102457379(SLC39A8)

CIZ:	142012758(SLC39A8)

CMY:	102933344(SLC39A8)

CCAY:

125635372(SLC39A8)

DCC:	119854697(SLC39A8)

CPIC:

101936280(SLC39A8)

TST:	117878403(SLC39A8)

CABI:

116826288(SLC39A8)

MRV:	120405939(SLC39A8)

ACS:	100555224(slc39a8)

ASAO:

132776961(SLC39A8)

PVT:	110085337(SLC39A8)

SUND:

121931776(SLC39A8)

PBI:	103057537(SLC39A8)

PMUR:

107298992(SLC39A8)

CTIG:

120311339(SLC39A8)

TSR:	106548336(SLC39A8)

PGUT:

117679889(SLC39A8)

PCAE:

139320391(SLC39A8)

APRI:

131203101(SLC39A8)

PTEX:

113434819(SLC39A8)

NSS:	113415344(SLC39A8)

VKO:	123023076(SLC39A8)

PMUA:

114604316(SLC39A8)

PRAF:

128421314(SLC39A8)

ZVI:	118083779(SLC39A8)

HCG:	128327545(SLC39A8)

GJA:	107105759(SLC39A8)

STOW:

125439630(SLC39A8)

EMC:	129337050(SLC39A8)

XLA:	108706737(slc39a8.S) 108710800(slc39a8.L)

XTR:	100487145(slc39a8)

NPR:	108789055(SLC39A8)

RTEM:

120918380(SLC39A8)

ACAT:

141110314(SLC39A8)

PADS:

140326761(SLC39A8)

BBUF:

120991698(SLC39A8)

BGAR:

122919793

DTC:	141100641(SLC39A8)

PWL:	138289972(SLC39A8)

MUO:	115461147(SLC39A8)

GSH:	117365933(SLC39A8)

DRE:	100002893(slc39a8)

SRX:	107733712 107747545 107749766 107750340

SANH:

107653340 107666352 107667057 107677395

SGH:	107585247 107587097 107587916

CCAR:

109055878 109069998(slc39a8) 109093300

CAUA:

113057101(slc39a8) 113057631 113113828

CGIB:

127969741 127971375 128027607

PTET:

122356648(slc39a8) 122357678

LROH:

127174761(slc39a8) 127176008

GRF:	141325426(slc39a8)

OMC:	131552182(slc39a8) 131553658

PPRM:

120460703 120479459(slc39a8)

RKG:	130095642 130102894(slc39a8)

MAMB:

125258726 125280386(slc39a8)

CIDE:

127494187 127524747

CERY:

137023025 137026736(slc39a8)

MASI:

127412136 127413957 127417609

TROS:

130558943(slc39a8) 130563666

TDW:	130431811(slc39a8) 130437815

MANU:

129415899(slc39a8) 129422104

PDAB:

135719468 135787201(slc39a8)

IPU:	108263549(slc39a8) 108277197

IFU:	128605448(slc39a8) 128624019

PHYP:

113543974 113546963(slc39a8)

SMEO:

124375290(slc39a8) 124396642

TFD:	113637511 113644994(slc39a8)

TVC:	132847158(slc39a8) 132861385

CGAR:

128529012(slc39a8) 128544399

NGRA:

132869132 132889298(slc39a8)

TRN:	134300080 134315075(slc39a8)

AMEX:

103022239 103035991(slc39a8)

CMAO:

118810250(slc39a8) 118821174

EEE:	113585858 113588039

CHAR:

105899613(slc39a8) 105911417

SPIL:

134067613(slc39a8) 134069366

ASAD:

121693185(slc39a8) 121693907

TRU:

101069036

TFS:	130513322(slc39a8)

TNG:	GSTEN00019943G001

TBEN:

117493887(slc39a8)

CGOB:

115027355(slc39a8)

PGEO:

117468212(slc39a8)

GACU:

117558912(slc39a8)

EMAC:

134881803(slc39a8)

ELY:	117266638(slc39a8)

EFO:	125900862(slc39a8)

SLUC:

116057582(slc39a8)

ECRA:

117936145(slc39a8)

ESP:	116686109(slc39a8)

PFLV:

114546332(slc39a8)

GAT:	120833090(slc39a8)

PPUG:

119227815(slc39a8)

AFB:	129103382(slc39a8)

CLUM:

117751604(slc39a8)

PSWI:

130201390(slc39a8)

CANA:

137787877(slc39a8)

CVE:	137877853(slc39a8)

MSAM:

119910378(slc39a8)

SCHU:

122861851(slc39a8)

CUD:	121525812 121526531

SPUL:

138591503(slc39a8)

LMIX:

132992810(slc39a8)

HTC:	141806048(slc39a8)

ALAT:

119005022(slc39a8)

ASTR:

137611177(slc39a8)

MZE:

101466283

ONL:	102076192(slc39a8)

OAU:	116315219(slc39a8)

OLA:	101159549(slc39a8)

OML:	112160087(slc39a8)

CSAI:

133461997(slc39a8)

XMA:	102230222(slc39a8)

XCO:	114134609(slc39a8)

XHE:

116708412

PRET:

103458197

PFOR:

103150062(slc39a8)

PLAI:

106952052(slc39a8)

PMEI:

106919174(slc39a8)

GAF:	122846123(slc39a8)

PPRL:

129377366(slc39a8)

CVG:

107096797

CTUL:

119779707(slc39a8)

GMU:	124855301(slc39a8)

NFU:	107391880(slc39a8)

ALIM:

106536672

NWH:	119427649(slc39a8)

AOCE:

111578757(slc39a8)

EJA:	138205193(slc39a8)

BFRE:

138628600(slc39a8)

MCEP:

125023750(slc39a8)

CSEM:

103381431(slc39a8)

POV:	109636290(slc39a8)

SSEN:

122783218(slc39a8)

SSOE:

131445360(slc39a8)

HHIP:

117756334(slc39a8)

HSP:	118116808(slc39a8)

PPLT:

128450770(slc39a8)

SMAU:

118285815(slc39a8)

LCF:

108876629

SDU:

111225479

SLAL:

111672801

XGL:	120795928(slc39a8)

HCQ:

109528149

SSCV:

125981283(slc39a8)

SBIA:

133513127

PEE:	133413022(slc39a8)

PTAO:

133487377(slc39a8)

BPEC:

110157422(slc39a8)

ENY:	140370297(slc39a8)

MALB:

109962409(slc39a8)

BSPL:

114848539(slc39a8)

SJO:	128375405(slc39a8)

SSCO:

134000908(slc39a8)

TTY:	137200001(slc39a8)

GMH:	115544449(slc39a8)

SASA:

106591239

STRU:

115161838(slc39a8)

OTW:	112256968(slc39a8)

OMY:	100136268(slc39a8)

OGO:	124046825(slc39a8)

OKI:	109876822(slc39a8)

OKE:	118402428(slc39a8)

OMM:	135539334(slc39a8)

OCLA:

139383922 139383955

SALP:

112071969

SNH:	120023058(slc39a8)

SFON:

129813307(slc39a8)

CCLU:

121544517(slc39a8)

ELS:	105015842(slc39a8)

OEP:	134026391(slc39a8)

SFM:	108920825 108930898

PKI:	111833171(slc39a8) 111853943

AANG:

118226963(slc39a8)

AROT:

135254780(slc39a8)

CCOG:

133131666(slc39a8)

LOC:	102693943(slc39a8)

PSPA:

121296307(slc39a8) 121321991

ARUT:

117408599(slc39a8) 117420867

PSEX:

120532798(slc39a8)

LCM:	102364396(SLC39A8)

CMK:

LVG:

AFIL:

API:

AGS:

RMD:

ACOO:

DVT:

CLEC:

HHAL:

LDA:

HVI:

MQU:	128986250 128987940

FOC:

TPAL:

ZNE:

CSEC:

PAME:

IEL:

HAMR:

FCD:

VDE:

VJA:

GOE:

DPTE:

DFR:	124495372 124499787

LPOL:

106457426

TSP:

Tsp_05260

LGI:	LOTGIDRAFT_117194

PVUL:

GAE:

MYI:

PMAX:

AIRR:

YBA:

RPHI:

SMM:	Smp_013440

OVI:	T265_14872

EGL:

EGR_06167

» show all

Reference

PMID:12504855

Authors

Begum NA, Kobayashi M, Moriwaki Y, Matsumoto M, Toyoshima K, Seya T

Title

Mycobacterium bovis BCG cell wall and lipopolysaccharide induce a novel gene, BIGM103, encoding a 7-TM protein: identification of a new protein family having Zn-transporter and Zn-metalloprotease signatures.

Journal

Genomics 80:630-45 (2002)
DOI:10.1006/geno.2002.7000

Sequence

[hsa:64116]

LinkDB

DBGET integrated database retrieval system