KEGG ORTHOLOGY: K15438

ORTHOLOGY: K15438

Entry

K15438                      KO

Symbol

AIMP2

Name

aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Disease

H00679

Hypomyelinating leukodystrophy

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03016 Transfer RNA biogenesis
    K15438  AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2
Transfer RNA biogenesis [BR:ko03016]
Eukaryotic type
  Aminoacyl-tRNA synthetases (AARSs)
   Multi-aminoacyl-tRNA synthetase complex (MSC)
    K15438  AIMP2; aminoacyl tRNA synthase complex-interacting multifunctional protein 2

Genes

HSA:	7965(AIMP2)

PTR:	741505(AIMP2)

PPS:	100973763(AIMP2)

GGO:	101134128(AIMP2)

PON:	100441057(AIMP2)

PPYG:

129041039(AIMP2)

NLE:	100602839(AIMP2)

HMH:	116810865(AIMP2)

SSYN:

129489568(AIMP2)

MCC:	717612(AIMP2)

MCF:	102117685(AIMP2)

MTHB:

126950511

MNI:	105497877(AIMP2)

CSAB:

103246802(AIMP2)

CATY:

105584349(AIMP2)

PANU:

101014304(AIMP2)

TGE:	112621779(AIMP2)

MLEU:

105551431(AIMP2)

RRO:	104665817(AIMP2)

RBB:	108523990(AIMP2)

TFN:	117073692(AIMP2)

PTEH:

111530518(AIMP2)

CANG:

105506308(AIMP2)

CJC:	103788717(AIMP2)

SBQ:	101045389(AIMP2)

CIMI:

108308074(AIMP2)

ANAN:

105719394(AIMP2)

CSYR:

103275510(AIMP2)

MMUR:

105868250(AIMP2)

LCAT:

123631544(AIMP2)

PCOQ:

105806014(AIMP2)

OGA:	105887889(AIMP2)

MMU:	231872(Aimp2)

MCAL:

110294029(Aimp2)

MPAH:

110312765(Aimp2)

RNO:	288480(Aimp2)

MCOC:

116068723(Aimp2)

ANU:	117697832(Aimp2) 117701957 117722528

ASYL:

127673135(Aimp2)

MUN:	110557412(Aimp2)

CGE:	100682533(Aimp2)

MAUA:

101839053(Aimp2)

PROB:

127237304(Aimp2)

PLEU:

114707578(Aimp2)

MORG:

121450030 121464759(Aimp2)

MFOT:

126489859

AAMP:

119824669(Aimp2)

NGI:	103726444(Aimp2)

HGL:	101710642(Aimp2)

CPOC:

100726477(Aimp2)

CCAN:

109692918(Aimp2)

DORD:

105990962(Aimp2)

DSP:	122113591(Aimp2)

DMER:

138834799(Aimp2)

PLOP:

125366786(Aimp2)

NCAR:

124961874 124970228

MMMA:

107155963(Aimp2)

ITI:	101954303(Aimp2)

OCU:

100354650

OPI:	101533387(AIMP2)

OCZ:	121162782(AIMP2)

TUP:	102476604(AIMP2)

GVR:	103598302(AIMP2)

CFA:	100856198 479752(AIMP2)

CLUD:

112646326(AIMP2) 125752147

VVP:	112910000(AIMP2)

VLG:	121479038 121487413(AIMP2)

NPO:	129519532(AIMP2)

AML:	100477352(AIMP2)

UMR:	103669973(AIMP2)

UAH:	113267935(AIMP2)

UAR:	123802490(AIMP2)

ELK:

111145994

LLV:

125090363

MPUF:

101675305(AIMP2)

MNP:	132026488(AIMP2)

MLK:	131819188(AIMP2)

NVS:	122895958(AIMP2)

ORO:	101380935(AIMP2)

EJU:	114197480(AIMP2)

ZCA:	113931885(AIMP2)

MLX:	117999347(AIMP2)

NSU:	110571923(AIMP2)

LWW:	102740238(AIMP2)

FCA:	101096777(AIMP2)

PYU:	121017568(AIMP2)

PCOO:

112860093(AIMP2)

PBG:	122471269(AIMP2)

PVIV:

125153997(AIMP2)

LRUF:

124519140

LGF:	123589236(AIMP2)

AJU:

106982609

PTG:	102967778(AIMP2)

PPAD:

109251203(AIMP2)

PUC:

125928286

PLEZ:

122210074(AIMP2)

HHV:	120228014(AIMP2)

BTA:	520979(AIMP2)

BOM:	102267891(AIMP2)

BIU:	109578407(AIMP2)

BBUB:

102394391(AIMP2)

BBIS:

104992769(AIMP2)

CHX:	102172592(AIMP2)

OAS:	100302342(AIMP2)

BTAX:

128065717(AIMP2)

CSUM:

138075849(AIMP2)

ODA:	120856094(AIMP2)

CCAD:

122432778(AIMP2)

MREE:

136160304(AIMP2)

OVR:	110141628(AIMP2)

MBEZ:

129545746(AIMP2)

SSC:	100514707(AIMP2)

CFR:	102510090(AIMP2)

CBAI:

105077318(AIMP2)

CDK:	105099375(AIMP2)

VPC:	102530908(AIMP2)

BACU:

103006139(AIMP2)

BMUS:

118880611(AIMP2)

LVE:	103073358(AIMP2)

OOR:	101272253(AIMP2)

LALB:

132504797(AIMP2)

GMF:	115846835(AIMP2)

DDP:	132438357(AIMP2)

DLE:	111181883(AIMP2)

PCAD:

102991581(AIMP2)

PSIU:

116739562(AIMP2)

PPHC:

136135571(AIMP2)

NASI:

112399893(AIMP2)

ECB:	100059133(AIMP2)

EPZ:	103555772(AIMP2)

EAI:	106840512(AIMP2)

MYB:	102257153(AIMP2)

MYD:	102768748(AIMP2)

MMYO:

118658081(AIMP2)

MLF:	102433487(AIMP2)

MDT:	132236001(AIMP2)

MYUM:

139010189(AIMP2)

PKL:	118711496(AIMP2)

EFUS:

103299142(AIMP2)

MNA:	107533923(AIMP2)

DRO:	112319444(AIMP2)

SHON:

118994995(AIMP2)

AJM:	119041502(AIMP2)

PDIC:

114510025(AIMP2)

PHAS:

123811954(AIMP2)

MMF:	118615253(AIMP2)

PPAM:

129067571(AIMP2)

HAI:	109380160(AIMP2)

RFQ:	117016442(AIMP2)

PALE:

102880132(AIMP2)

PGIG:

120616591(AIMP2)

PVP:	105294580(AIMP2)

RAY:	107515919(AIMP2)

MJV:	108404659(AIMP2)

TOD:	119241667(AIMP2)

SARA:

101556290(AIMP2)

SFUM:

130036633(AIMP2)

SETR:

126030462(AIMP2)

TMU:

101355023

ETF:	101660366(AIMP2)

DNM:	101434591(AIMP2)

MDO:	100020378(AIMP2)

GAS:	123231191(AIMP2)

SHR:	100914184(AIMP2)

AFZ:

127564389

PCW:	110193463(AIMP2)

TVP:	118833987(AIMP2)

PBRV:

138158734(AIMP2)

MLAO:

141503057(AIMP2)

OAA:	100076257(AIMP2)

TACU:

119941863(AIMP2)

GGA:	769030(AIMP2)

PCOC:

116237369(AIMP2)

MGP:	100543017(AIMP2)

CJO:	107320611(AIMP2)

TPAI:

128079384(AIMP2)

LMUT:

125700519(AIMP2)

NMEL:

110405849(AIMP2)

APLA:

101802376(AIMP2)

ACYG:

106033380(AIMP2)

CATA:

118249070(AIMP2)

AFUL:

116495445(AIMP2)

TGU:	100226087(AIMP2)

LSR:	110475520(AIMP2)

SCAN:

103817663(AIMP2)

PMOA:

120512892(AIMP2)

OTC:	121334355(AIMP2)

PRUF:

121350981(AIMP2)

ATRC:

139598108(AIMP2)

GFR:	102034781(AIMP2)

FAB:	101814959(AIMP2)

OMA:	130259352(AIMP2)

PHI:	102112291(AIMP2)

PMAJ:

107211070(AIMP2)

CCAE:

111922581(AIMP2)

CCW:	104685050(AIMP2)

CBRC:

103615609(AIMP2)

ACOE:

138118619(AIMP2)

ETL:	114054735(AIMP2)

ZAB:	102072352(AIMP2)

ZLE:	135454102(AIMP2)

ACHL:

103797954(AIMP2)

SVG:	106849136(AIMP2)

MMEA:

130585710(AIMP2)

HRT:	120759593(AIMP2)

SATI:

136367861(AIMP2)

CCIC:

134050490(AIMP2)

FPG:	101913124(AIMP2)

FCH:	102050523(AIMP2)

CCRI:

104168259(AIMP2)

NNT:	104400916(AIMP2)

SHAB:

115606506(AIMP2)

ACUN:

113485868(AIMP2)

TALA:

104368017(AIMP2)

ACHC:

115335757(AIMP2)

HALD:

104311539(AIMP2)

HLE:	104833521(AIMP2)

AGEN:

126034144

HHAR:

128134549(AIMP2)

GCL:

127022409

CSTI:

104558677(AIMP2)

LDI:	104346701(AIMP2)

MNB:	103777844(AIMP2)

DPUB:

104299705(AIMP2)

PPUS:

135180914(AIMP2)

AVIT:

104269288(AIMP2)

BRHI:

104488005(AIMP2)

EGZ:	104135816(AIMP2)

NNI:	104015199(AIMP2)

PCRI:

104027545(AIMP2)

PCAO:

104053022(AIMP2)

PADL:

103913551(AIMP2)

AFOR:

103904836(AIMP2)

FGA:	104075347(AIMP2)

CBOR:

142089134(AIMP2)

GSTE:

104251604(AIMP2)

CBOY:

140659189(AIMP2)

MAME:

142416121(AIMP2)

CLV:	102094998(AIMP2)

CNIC:

135994464(AIMP2)

MUI:	104534828(AIMP2)

PGUU:

104463304(AIMP2)

PLET:

104615874(AIMP2)

EHS:	104509488(AIMP2)

CMAC:

104474194(AIMP2)

CUCA:

104063793(AIMP2)

TEO:	104371011(AIMP2)

BREG:

104638302(AIMP2)

OHA:	104329100(AIMP2)

ACAR:

104517639(AIMP2)

CPEA:

104393805(AIMP2)

CVF:	104287533(AIMP2)

RTD:	128914108(AIMP2)

CRID:

134519945(AIMP2)

LMIC:

141747772(AIMP2)

AAM:	106491340(AIMP2)

AROW:

112974209(AIMP2)

NPD:	112959822(AIMP2)

TGT:	104575887(AIMP2)

DNE:	112992875(AIMP2)

SCAM:

104149738(AIMP2)

ASN:	102384800(AIMP2)

AMJ:	102576990(AIMP2)

CPOO:

109314864(AIMP2)

GGN:	109294488(AIMP2)

PSS:	102455917(AIMP2)

CIZ:	142021422(AIMP2)

CMY:	102946466(AIMP2)

CCAY:

125644333(AIMP2)

DCC:	119862918(AIMP2)

CPIC:

101950815(AIMP2)

TST:	117884221(AIMP2)

CABI:

116830453(AIMP2)

MRV:	120374098(AIMP2)

ACS:	100562511(aimp2)

ASAO:

132782031(AIMP2)

PVT:	110082195(AIMP2)

SUND:

121914252(AIMP2)

PBI:	103065389(AIMP2)

PMUR:

107291744(AIMP2)

CTIG:

120315649(AIMP2)

TSR:	106552495(AIMP2)

PGUT:

117678085(AIMP2)

PCAE:

139325204(AIMP2)

PTEX:

113452692 113452697

NSS:	113425278(AIMP2)

VKO:	123025038(AIMP2)

PMUA:

114584274(AIMP2)

PRAF:

128401301(AIMP2)

ZVI:	118093258(AIMP2)

HCG:	128326340 128336406(AIMP2)

GJA:	107123051(AIMP2)

STOW:

125431102(AIMP2)

EMC:	129338532(AIMP2)

XLA:	380517(aimp2.L) 443824(aimp2.S)

XTR:	448040(aimp2)

NPR:	108795513(AIMP2)

RTEM:

120943481(AIMP2)

ACAT:

141101725(AIMP2)

BBUF:

121007820(AIMP2)

BGAR:

122945063 122945114

DTC:	141047785(AIMP2)

PWL:	138261320(AIMP2)

MUO:	115475710(AIMP2)

GSH:	117369287(AIMP2)

DRE:	406647(aimp2)

SRX:	107713960 107724742

SANH:

107665836 107691232

SGH:	107548699 107565874

CCAR:

109096997 109097011

CAUA:

113046610(aimp2) 113052499

CGIB:

127940747 127953752

PTET:

122341873(aimp2)

LROH:

127163348(aimp2)

GRF:	141325295(aimp2)

OMC:	131538028(aimp2)

PPRM:

120490108(aimp2)

RKG:	130085582(aimp2)

MAMB:

125266374(aimp2)

CIDE:

127509359

CERY:

137013308(aimp2)

MASI:

127450793 127451175

TROS:

130561502(aimp2)

TDW:	130426321(aimp2)

MANU:

129427825(aimp2)

PDAB:

135780264(aimp2)

IPU:

108259713

IFU:	128600375(aimp2)

PHYP:

113527865(aimp2)

SMEO:

124396339(aimp2)

TFD:	113638144(aimp2)

TVC:	132861272(aimp2)

CGAR:

128544158(aimp2)

NGRA:

132868668(aimp2)

TRN:	134336179(aimp2)

AMEX:

103032317(aimp2)

CMAO:

118821606(aimp2)

EEE:	113569790(aimp2)

CHAR:

105898833(aimp2)

SPIL:

134076930(aimp2)

ASAD:

121705925(aimp2)

TRU:	101079361(aimp2)

TFS:	130514960(aimp2)

TNG:	GSTEN00022461G001

LCO:	104918848(aimp2)

NCC:	104946074(aimp2)

TBEN:

117493223(aimp2)

CGOB:

115011628(aimp2)

PGEO:

117451577(aimp2)

GACU:

117548649(aimp2)

EMAC:

134878190(aimp2)

ELY:	117268413(aimp2)

EFO:	125879043(aimp2)

PLEP:

121956662(aimp2)

SLUC:

116059497(aimp2)

ECRA:

117958536(aimp2)

ESP:	116703259(aimp2)

PFLV:

114569728(aimp2)

GAT:	120827668(aimp2)

PPUG:

119220627(aimp2)

AFB:	129098759(aimp2)

CLUM:

117734992(aimp2)

PSWI:

130188708(aimp2)

CANA:

137786630(aimp2)

CVE:	137878612(aimp2)

MSAM:

119888747(aimp2)

SCHU:

122869096(aimp2)

CUD:	121529165(aimp2)

SPUL:

138602894(aimp2)

LMIX:

132995536(aimp2)

HTC:	141809542(aimp2)

ALAT:

119014593(aimp2)

ASTR:

137609639(aimp2)

MZE:	101481380(aimp2)

ONL:	100692095(aimp2)

OAU:	116312648(aimp2)

OLA:	101167042(aimp2)

OML:	112146896(aimp2)

CSAI:

133421513(aimp2)

XMA:	102231962(aimp2)

XCO:	114160291(aimp2)

XHE:	116735715(aimp2)

PRET:

103469265(aimp2)

PFOR:

103141680 103141688

PLAI:

106937705(aimp2)

PMEI:

106903629(aimp2)

GAF:	122822468(aimp2)

PPRL:

129363112(aimp2)

CVG:	107097587(aimp2)

CTUL:

119772664(aimp2)

GMU:	124863521 124863767

NFU:	107376573(aimp2)

KMR:	108239196(aimp2)

ALIM:

106536764(aimp2)

NWH:	119421604(aimp2)

AOCE:

111577374(aimp2)

EJA:	138198059(aimp2)

BFRE:

138629691(aimp2)

MCEP:

124997949(aimp2)

CSEM:

103392899(aimp2)

POV:	109639408(aimp2)

SSEN:

122785524(aimp2)

SSOE:

131475590(aimp2)

HHIP:

117766969(aimp2)

HSP:	118123294(aimp2)

PPLT:

128459087(aimp2)

SMAU:

118289501(aimp2)

LCF:

108879994

SDU:	111227315(aimp2)

SLAL:

111645886(aimp2)

XGL:	120805156(aimp2)

HCQ:	109527729(aimp2)

SSCV:

125983200(aimp2)

SBIA:

133514392(aimp2)

PEE:	133414670(aimp2)

PTAO:

133465568(aimp2)

BPEC:

110172195(aimp2)

ENY:	140358529(aimp2)

MALB:

109969473(aimp2)

BSPL:

114860447(aimp2)

SJO:	128378526(aimp2)

SSCO:

133999547(aimp2)

TTY:	137201355(aimp2)

GMH:	115533416(aimp2)

SASA:

106601790 106606656

STRU:

115171689 115205636

OTW:	112226254(aimp2)

OMY:	110485235(aimp2) 110539039

OGO:	123999413(aimp2)

OKI:	109882679 116370946

OKE:	118372662(aimp2)

OMM:	135554589(aimp2)

OCLA:

139365095

SALP:

111971384(aimp2)

SNH:	120043008(aimp2)

SFON:

129833384 129833389

CCLU:

121551632 121568800

ELS:	105013013(aimp2)

OEP:	134012226(aimp2)

SFM:	108932958(aimp2)

PKI:	111855908(aimp2)

AANG:

118216051(aimp2)

AROT:

135243524(aimp2)

CCOG:

133113892(aimp2)

LOC:	102691499(aimp2)

PSPA:

121294174(aimp2)

ARUT:

117418110(aimp2)

PSEX:

120543391(aimp2)

LCM:	102365411(AIMP2)

CMK:	103178703(aimp2)

RTP:	109912929(aimp2)

CPLA:

122560591(aimp2)

HOC:	132825172(aimp2)

SCAU:

119978290(aimp2)

LERI:

129706937(aimp2)

HAKA:

140735285(aimp2)

PMRN:

116956270(AIMP2)

LRJ:	133348039(AIMP2)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

PFLL:

DME:	Dmel_CG12304(AIMP2)

DER:

6544535

DSE:

6605798

DSI:	Dsimw501_GD14558(Dsim_GD14558)

DYA:	Dyak_GE19834 Dyak_GE22257

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI11682

DAZ:

108613846

DNV:

108651464

DHE:

111597274

DVI:	116650471(AIMP2) 6622060

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

MDE:	101891050 131801493

SCAC:

106087070

LCQ:

111679908

LSQ:

119606648

CVJ:	135953364(AIMP2)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

AALI:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ011915

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

TLN:

HST:

DQU:

CFO:

FEX:

PMEC:

LHU:	105678006(AIMP2)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LBD:

MDL:

CGLO:

CTYP:

FAS:

DAM:

AGIF:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138126386(AIMP2)

DPA:

109539555

ESIM:

136408167(AIMP2)

EFOR:

136341780(AIMP2)

SOY:

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_206092

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

BPHI:

137930521(AIMP2)

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

ONU:

ATRA:

GMW:

PXY:

PGW:

LGLY:

CSTB:

CFUM:

141428152(AIMP2)

CCRN:

API:

DNX:

AGS:

RMD:

BTAB:

DCI:

CLEC:

HHAL:

106688668(AIMP2)

NLU:

111064410

LDA:	142323719(AIMP2)

HVI:

124367864

MQU:

128994426

PHU:	Phum_PHUM320300

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138708780(AIMP2)

BROR:

IEL:

HAMR:

FCD:

DPX:	DAPPUDRAFT_311613

AFRA:

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

CVS:	136977822(AIMP2)

PTEP:

ABRU:

UDV:

SDM:

LPOL:

LGI:	LOTGIDRAFT_106366

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_050250

SHX:	MS3_00008057

LLON:

135491519

NVE:	116606132 5516921

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_62144

AQU:

100638030

MBR:	MONBRDRAFT_35487

SRE:	PTSG_05017

» show all

Reference

PMID:16135753

Authors

Ko HS, von Coelln R, Sriram SR, Kim SW, Chung KK, Pletnikova O, Troncoso J, Johnson B, Saffary R, Goh EL, Song H, Park BJ, Kim MJ, Kim S, Dawson VL, Dawson TM

Title

Accumulation of the authentic parkin substrate aminoacyl-tRNA synthetase cofactor, p38/JTV-1, leads to catecholaminergic cell death.

Journal

J Neurosci 25:7968-78 (2005)
DOI:10.1523/JNEUROSCI.2172-05.2005

Sequence

[hsa:7965] [mmu:231872]

LinkDB

DBGET integrated database retrieval system