KEGG   ORTHOLOGY: K15676
Entry
K15676                      KO                                     
Symbol
rhiC
Name
rhizoxin biosynthesis, polyketide synthase RhiC
Brite
KEGG Orthology (KO) [BR:ko00001]
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K15676  rhiC; rhizoxin biosynthesis, polyketide synthase RhiC
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   trans-AT PKS
    Rhizoxin hybrid PKS-NRPS
     K15676  rhiC; rhizoxin biosynthesis, polyketide synthase RhiC
Genes
PFL: PFL_2990(rzxC)
PSOS: POS17_2971(rzxC)
RSL: RPSI07_mp0403(rhiC)
BRH: RBRH_02577(rhiC)
Reference
PMID:17154220
  Authors
Partida-Martinez LP, Hertweck C
  Title
A gene cluster encoding rhizoxin biosynthesis in "Burkholderia rhizoxina", the bacterial endosymbiont of the fungus Rhizopus microsporus.
  Journal
Chembiochem 8:41-5 (2007)
DOI:10.1002/cbic.200600393
  Sequence
[brh:RBRH_02577]
Reference
PMID:17609750
  Authors
Brendel N, Partida-Martinez LP, Scherlach K, Hertweck C
  Title
A cryptic PKS-NRPS gene locus in the plant commensal Pseudomonas fluorescens Pf-5 codes for the biosynthesis of an antimitotic rhizoxin complex.
  Journal
Org Biomol Chem 5:2211-3 (2007)
DOI:10.1039/b707762a
Reference
PMID:20033973
  Authors
Kusebauch B, Busch B, Scherlach K, Roth M, Hertweck C
  Title
Functionally distinct modules operate two consecutive alpha,beta-->beta,gamma double-bond shifts in the rhizoxin polyketide assembly line.
  Journal
Angew Chem Int Ed Engl 49:1460-4 (2010)
DOI:10.1002/anie.200905467
Reference
PMID:19266509
  Authors
Kusebauch B, Busch B, Scherlach K, Roth M, Hertweck C
  Title
Polyketide-chain branching by an enzymatic Michael addition.
  Journal
Angew Chem Int Ed Engl 48:5001-4 (2009)
DOI:10.1002/anie.200900277
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