KEGG ORTHOLOGY: K15715

ORTHOLOGY: K15715

Entry

K15715                      KO

Symbol

ZNRF4

Name

E3 ubiquitin-protein ligase ZNRF4 [EC:2.3.2.27]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   04121 Ubiquitin system
    K15715  ZNRF4; E3 ubiquitin-protein ligase ZNRF4
Enzymes [BR:ko01000]
2. Transferases
  2.3  Acyltransferases
   2.3.2  Aminoacyltransferases
    2.3.2.27  RING-type E3 ubiquitin transferase
     K15715  ZNRF4; E3 ubiquitin-protein ligase ZNRF4
Ubiquitin system [BR:ko04121]
Ubiquitin ligases (E3)
  Single Ring-finger type E3
   Other single Ring-finger type E3
    K15715  ZNRF4; E3 ubiquitin-protein ligase ZNRF4

Genes

HSA:	148066(ZNRF4)

PTR:	468678(ZNRF4)

PPS:	100979717(ZNRF4)

GGO:	101145565(ZNRF4)

PON:	100459352(ZNRF4)

PPYG:

129020390(ZNRF4)

NLE:	100590270(ZNRF4)

HMH:	116483028(ZNRF4)

SSYN:

129467057(ZNRF4)

MCC:	695996(ZNRF4)

MCF:	101864779(ZNRF4)

MTHB:

126942656

MNI:	105485013(ZNRF4)

CSAB:

103233737(ZNRF4)

CATY:

105591830(ZNRF4)

PANU:

101017475(ZNRF4)

TGE:	112612550(ZNRF4)

MLEU:

105530047(ZNRF4)

RRO:	104665400(ZNRF4)

RBB:	108512138(ZNRF4)

TFN:	117075553(ZNRF4)

PTEH:

111521977(ZNRF4)

CANG:

105512856(ZNRF4)

CJC:	100394352(ZNRF4)

SBQ:	101041791(ZNRF4)

CIMI:

108304265(ZNRF4)

ANAN:

105705888(ZNRF4)

MMUR:

105869691(ZNRF4)

LCAT:

123638206(ZNRF4)

PCOQ:

105811854(ZNRF4)

OGA:	105887454(ZNRF4)

MMU:	20834(Znrf4)

MCAL:

110284064(Znrf4)

MPAH:

110336119(Znrf4)

RNO:	301127(Znrf4)

MCOC:

116074568(Znrf4)

ANU:	117706159(Znrf4)

ASYL:

127693004(Znrf4)

MUN:	110546217(Znrf4)

CGE:	100770816(Znrf4)

MAUA:

101824818(Znrf4)

PROB:

127216768(Znrf4)

PLEU:

114685104(Znrf4)

MORG:

121459235(Znrf4)

MFOT:

126490400

AAMP:

119818455(Znrf4)

NGI:	103737389(Znrf4)

HGL:	101715435(Znrf4)

CCAN:

109692016(Znrf4)

DSP:	122122718(Znrf4)

PLOP:

125347640(Znrf4)

NCAR:

124968759

ITI:	101955111(Znrf4)

OPI:	101528987(ZNRF4)

TUP:	102502260(ZNRF4)

GVR:	103590762(ZNRF4)

CFA:	485029(ZNRF4)

CLUD:

112666972(ZNRF4)

VVP:	112935553(ZNRF4)

VLG:	121494664(ZNRF4)

NPO:	129522240(ZNRF4)

AML:	100467948(ZNRF4)

UMR:	121102441(ZNRF4)

UAH:	113242666(ZNRF4)

UAR:	123796789(ZNRF4)

ELK:

111161899

LLV:

125088257

MPUF:

101672964(ZNRF4)

MNP:	132009589(ZNRF4)

MLK:	131825712(ZNRF4)

NVS:	122910813(ZNRF4)

ORO:	101364759(ZNRF4)

EJU:	114226100(ZNRF4)

ZCA:	113918800(ZNRF4)

MLX:	118005624(ZNRF4)

NSU:	110594061(ZNRF4)

LWW:	102746292(ZNRF4)

FCA:	105261107(ZNRF4)

PYU:	121021487(ZNRF4)

PBG:	122486753(ZNRF4)

PVIV:

125148739(ZNRF4)

LRUF:

124525174

LGF:	123604885(ZNRF4)

AJU:

113596367

PPAD:

109255855(ZNRF4)

PUC:

125928889

PLEZ:

122213808(ZNRF4)

HHV:	120242045(ZNRF4)

BTA:	517394(ZNRF4)

BOM:	102278957(ZNRF4)

BIU:	109560959(ZNRF4)

BBUB:

102393321(ZNRF4)

BBIS:

104979907(ZNRF4)

CHX:	102183866(ZNRF4)

OAS:	101112567(ZNRF4)

BTAX:

128051667(ZNRF4)

CSUM:

138086197(ZNRF4)

ODA:	120864556(ZNRF4)

CCAD:

122439285(ZNRF4)

MREE:

136156952(ZNRF4)

OVR:	110131239(ZNRF4)

MBEZ:

129558320(ZNRF4)

SSC:	100511549(ZNRF4)

CFR:	102516159(ZNRF4)

CBAI:

105078384(ZNRF4)

CDK:	105091782(ZNRF4)

VPC:	102533421(ZNRF4)

BACU:

103014877

BMUS:

118892645(ZNRF4)

LVE:

103075658

OOR:	101284767(ZNRF4)

LALB:

132518490(ZNRF4)

DLE:	111165978(ZNRF4)

PCAD:

102991929(ZNRF4)

PSIU:

116750603(ZNRF4)

NASI:

112400310(ZNRF4)

ECB:	111774187(ZNRF4)

EPZ:	103545854(ZNRF4)

EAI:	106832390(ZNRF4)

MYB:	102254968(ZNRF4)

MYD:	102756207(ZNRF4)

MMYO:

118659167(ZNRF4)

MLF:	111828363(ZNRF4)

MDT:	132234213(ZNRF4)

MYUM:

139009780(ZNRF4)

PKL:	118731394(ZNRF4)

EFUS:

103294384(ZNRF4)

MNA:	107525703(ZNRF4)

DRO:	112312257(ZNRF4)

SHON:

118984635(ZNRF4)

AJM:	119063709(ZNRF4)

PDIC:

114502414(ZNRF4)

PHAS:

123813907(ZNRF4)

MMF:	118615132(ZNRF4)

PPAM:

129061450(ZNRF4)

HAI:	109388559(ZNRF4)

RFQ:	117038526(ZNRF4)

PALE:

102882351(ZNRF4)

PGIG:

120615467(ZNRF4)

PVP:	105301096(ZNRF4)

RAY:	107511363(ZNRF4)

TOD:	119239848(ZNRF4)

SARA:

105943377(ZNRF4)

SETR:

126030119(ZNRF4)

LAV:	100665745(ZNRF4)

TMU:

101353916

ETF:	101646843(ZNRF4)

DNM:

101412833

MDO:	100024804(ZNRF4)

GAS:	123232129(ZNRF4)

SHR:	100924723(ZNRF4)

AFZ:

127541360

PCW:	110197493(ZNRF4)

TVP:	118848388(ZNRF4)

PBRV:

138160168(ZNRF4)

OAA:	100680810(ZNRF4)

TACU:

119919712(ZNRF4)

GGA:	420152(ZNRF4)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

CATA:

AFUL:

116499250(ZNRF4)

FCH:	102045908(ZNRF4)

CCRI:

NNT:

SHAB:

TALA:

ACHC:

115349034(ZNRF4)

HALD:

HLE:

AGEN:

HHAR:

GCL:

DPUB:

PPUS:

135192051(ZNRF4)

BRHI:

NNI:

PCRI:

PCAO:

PADL:

AFOR:

FGA:

GSTE:

CLV:

PLET:

CUCA:

OHA:

ACAR:

CPEA:

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

ASN:	112549195(ZNRF4)

AMJ:	106737368(ZNRF4)

CPOO:

109320556 109320557 109320558(ZNRF4)

GGN:	109295048 109295049 109295050

PSS:

102462294

CMY:

102936691

CCAY:

125627255 125627256 125627257

DCC:	119848489 119848520 119848521

CPIC:

101930864

TST:	117868752 117868767 117869114

CABI:

116814623 116814695 116814761

MRV:	120391937 120391939 120391940

ACS:

100554263

ASAO:

132781474(ZNRF4)

PVT:

110079330

SUND:

121936560 121936825 121936827

PBI:

PMUR:

CTIG:

PGUT:

APRI:

131188209(ZNRF4)

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:	128346845 128346846

GJA:

107108351

STOW:

125433291

EMC:	129329850 129329851

» show all

Reference

PMID:21205830

Authors

Neutzner A, Neutzner M, Benischke AS, Ryu SW, Frank S, Youle RJ, Karbowski M

Title

A systematic search for endoplasmic reticulum (ER) membrane-associated RING finger proteins identifies Nixin/ZNRF4 as a regulator of calnexin stability and ER homeostasis.

Journal

J Biol Chem 286:8633-43 (2011)
DOI:10.1074/jbc.M110.197459

Sequence

[hsa:148066]

LinkDB

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