KEGG   ORTHOLOGY: K15741
Entry
K15741                      KO                                     
Symbol
MAM1, IMS3
Name
methylthioalkylmalate synthase 1 [EC:2.3.3.17]
Pathway
map00966  Glucosinolate biosynthesis
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
Reaction
R08619  acetyl-CoA:4-methylthio-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R08623  acetyl-CoA:5-methylthio-2-oxopentanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00966 Glucosinolate biosynthesis
    K15741  MAM1, IMS3; methylthioalkylmalate synthase 1
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.17  methylthioalkylmalate synthase
     K15741  MAM1, IMS3; methylthioalkylmalate synthase 1
Other DBs
GO: 0010177
Genes
ATH: AT5G23010(MAM1)
ALY: 9308098 9308099 9308100
CRB: 17881318 17883860
CSAT: 104706601 104706602 104706603 104736315 104736316 104736317 104770650 104770651 104770652
EUS: EUTSA_v10003976mg EUTSA_v10004072mg EUTSA_v10005522mg
BRP: 103853322 103854915 103860537(MAM3-1) 103860538(MAM1-1) 103861112
BNA: 106377268 106377269 106382716 106434595 106434598 106434605 106444270
BOE: 106301761 106324531 106324637 106325524
RSZ: 108813467 108835158 108848454 130497108 130507828
QSA: O6P43_017013
Reference
PMID:14740211
  Authors
Textor S, Bartram S, Kroymann J, Falk KL, Hick A, Pickett JA, Gershenzon J
  Title
Biosynthesis of methionine-derived glucosinolates in Arabidopsis thaliana: recombinant expression and characterization of methylthioalkylmalate synthase, the condensing enzyme of the chain-elongation cycle.
  Journal
Planta 218:1026-35 (2004)
DOI:10.1007/s00425-003-1184-3
  Sequence
[ath:AT5G23010]
LinkDB

KEGG   ORTHOLOGY: K15742
Entry
K15742                      KO                                     
Symbol
MAM3, IMS2
Name
methylthioalkylmalate synthase 3 [EC:2.3.3.17]
Pathway
map00966  Glucosinolate biosynthesis
map01110  Biosynthesis of secondary metabolites
map01210  2-Oxocarboxylic acid metabolism
Reaction
R08619  acetyl-CoA:4-methylthio-2-oxobutanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R08623  acetyl-CoA:5-methylthio-2-oxopentanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R08627  acetyl-CoA:6-methylthio-2-oxohexanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R08631  acetyl-CoA:7-methylthio-2-oxoheptanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R08640  acetyl-CoA:8-methylthio-2-oxooctanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
R08644  acetyl-CoA:9-methylthio-2-oxononanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00966 Glucosinolate biosynthesis
    K15742  MAM3, IMS2; methylthioalkylmalate synthase 3
Enzymes [BR:ko01000]
 2. Transferases
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.17  methylthioalkylmalate synthase
     K15742  MAM3, IMS2; methylthioalkylmalate synthase 3
Other DBs
GO: 0010177
Genes
ATH: AT5G23020(IMS2)
CRB: 17883723
QSA: O6P43_017014
Reference
PMID:17369439
  Authors
Textor S, de Kraker JW, Hause B, Gershenzon J, Tokuhisa JG
  Title
MAM3 catalyzes the formation of all aliphatic glucosinolate chain lengths in Arabidopsis.
  Journal
Plant Physiol 144:60-71 (2007)
DOI:10.1104/pp.106.091579
  Sequence
[ath:AT5G23020]
LinkDB

KEGG   REACTION: R08623
Entry
R08623                      Reaction                               
Name
acetyl-CoA:5-methylthio-2-oxopentanoate C-acetyltransferase (thioester-hydrolysing, carboxymethyl-forming)
Definition
2-Oxo-5-methylthiopentanoic acid + Acetyl-CoA + H2O <=> 2-(3'-Methylthio)propylmalic acid + CoA
Equation
C17211 + C00024 + C00001 <=> C17214 + C00010
Reaction class
RC00004  C00010_C00024
RC00067  C17211_C17214
Enzyme
2.3.3.17
Pathway
rn00966  Glucosinolate biosynthesis
rn01210  2-Oxocarboxylic acid metabolism
Brite
Enzymatic reactions [BR:br08201]
 2. Transferase reactions
  2.3  Acyltransferases
   2.3.3  Acyl groups converted into alkyl groups on transfer
    2.3.3.17
     R08623  2-Oxo-5-methylthiopentanoic acid + Acetyl-CoA + H2O <=> 2-(3'-Methylthio)propylmalic acid + CoA
Orthology
K15741  methylthioalkylmalate synthase 1 [EC:2.3.3.17]
K15742  methylthioalkylmalate synthase 3 [EC:2.3.3.17]
LinkDB

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