KEGG   ORTHOLOGY: K15800
Entry
K15800                      KO                                     
Symbol
GAO
Name
germacrene A oxidase [EC:1.14.14.95]
Pathway
map00909  Sesquiterpenoid and triterpenoid biosynthesis
map01110  Biosynthesis of secondary metabolites
Reaction
R09548  germacra-1(10),4,11(13)-trien-12-ol,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase
R09549  (+)-germacrene-A,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12-hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K15800  GAO; germacrene A oxidase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.95  germacrene A hydroxylase
     K15800  GAO; germacrene A oxidase
Other DBs
GO: 0102260
Genes
HAN: 110898214
LSV: 111882413 111906166 111906167
CCAV: 112515273 112515404 112515606
AG: ADF32078(GAO1) ADF43080(CiGAO)
Reference
  Authors
Nguyen DT, Gopfert JC, Ikezawa N, Macnevin G, Kathiresan M, Conrad J, Spring O, Ro DK
  Title
Biochemical conservation and evolution of germacrene A oxidase in asteraceae.
  Journal
J Biol Chem 285:16588-98 (2010)
DOI:10.1074/jbc.M110.111757
  Sequence
LinkDB

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