KEGG   ORTHOLOGY: K15804
Entry
K15804                      KO                                     
Symbol
EAS
Name
5-epiaristolochene/(+)-2-epi-prezizaene/(-)-alpha-cedrene synthase [EC:4.2.3.61 4.2.3.226 4.2.3.227]
Pathway
map00909  Sesquiterpenoid and triterpenoid biosynthesis
Reaction
R09574  (2E,6E)-farnesyl-diphosphate diphosphate-lyase [(+)-5-epiaristolochene-forming]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K15804  EAS; 5-epiaristolochene/(+)-2-epi-prezizaene/(-)-alpha-cedrene synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.3  Acting on phosphates
    4.2.3.61  5-epiaristolochene synthase
     K15804  EAS; 5-epiaristolochene/(+)-2-epi-prezizaene/(-)-alpha-cedrene synthase
    4.2.3.226  (+)-2-epi-prezizaene synthase
     K15804  EAS; 5-epiaristolochene/(+)-2-epi-prezizaene/(-)-alpha-cedrene synthase
    4.2.3.227  (-)-alpha-cedrene synthase
     K15804  EAS; 5-epiaristolochene/(+)-2-epi-prezizaene/(-)-alpha-cedrene synthase
Genes
SSTN: 125843948 125843949 125844385 125844595
SDUL: 129886310 129886325
LBB: 132615708 132615734 132615770 132615849
NTA: 107821548 142165746 142165747 142165748 142167922 142167925 142167926 142167927 142167928 142167929 142167930
NSY: 104229039
NTO: 104091728
NAU: 109214804
EGT: 105951625
SSPL: 121781268
SMIL: 130986755 130986770 130986772
APAN: 127258817
PTAB: 142547644
CARB: 113705893
AG: AAA19216(EAS) AAP05761(EAS)
 » show all
Reference
PMID:9295271
  Authors
Starks CM, Back K, Chappell J, Noel JP
  Title
Structural basis for cyclic terpene biosynthesis by tobacco 5-epi-aristolochene synthase.
  Journal
Science 277:1815-20 (1997)
DOI:10.1126/science.277.5333.1815
  Sequence
Reference
  Authors
Noel JP, Dellas N, Faraldos JA, Zhao M, Hess BA Jr, Smentek L, Coates RM, O'Maille PE.
  Title
Structural elucidation of cisoid and transoid cyclization pathways of a sesquiterpene synthase using 2-fluorofarnesyl diphosphates.
  Journal
ACS Chem Biol 5:377-92 (2010)
DOI:10.1021/cb900295g
  Sequence
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