KEGG ORTHOLOGY: K15839

ORTHOLOGY: K15839

Entry

K15839                      KO

Symbol

GPSM1, AGS3

Name

G-protein signaling modulator 1

Pathway

map05030

Cocaine addiction

Brite

KEGG Orthology (KO) [BR:ko00001]
09160 Human Diseases
  09165 Substance dependence
   05030 Cocaine addiction
    K15839  GPSM1, AGS3; G-protein signaling modulator 1

Other DBs

GO:

0005096

Genes

HSA:	26086(GPSM1)

PTR:	464915(GPSM1)

GGO:	101145847(GPSM1)

PON:	100444986(GPSM1)

PPYG:

129043983(GPSM1)

NLE:	101178942(GPSM1)

HMH:	116475860(GPSM1)

SSYN:

129478686(GPSM1)

MCF:	102145199(GPSM1)

MTHB:

126936933

MNI:

105471924

CSAB:

103239632(GPSM1)

CATY:

105580565(GPSM1)

PANU:

100998349(GPSM1)

TGE:	112608372(GPSM1)

MLEU:

105543247(GPSM1)

RRO:	104669678(GPSM1)

TFN:	117099159(GPSM1)

PTEH:

111553099(GPSM1)

CANG:

105522714(GPSM1)

CJC:	100388990(GPSM1)

SBQ:	101039352(GPSM1)

CIMI:

108287320(GPSM1)

ANAN:

105712260(GPSM1)

CSYR:

103250621(GPSM1)

MMUR:

105880790(GPSM1)

LCAT:

123645792(GPSM1)

PCOQ:

105818723(GPSM1)

OGA:	100944954(GPSM1)

MMU:	67839(Gpsm1)

MCAL:

110284004(Gpsm1)

MPAH:

110318698(Gpsm1)

RNO:	246254(Gpsm1)

MCOC:

116089848(Gpsm1)

ANU:	117710135(Gpsm1)

ASYL:

127685083(Gpsm1)

MUN:	110550862(Gpsm1)

CGE:	100758972(Gpsm1)

MAUA:

101840211(Gpsm1)

PROB:

127222624(Gpsm1)

PLEU:

114692814(Gpsm1)

MORG:

121462913(Gpsm1)

MFOT:

126509355

AAMP:

119818664(Gpsm1)

NGI:	103741204(Gpsm1)

HGL:	101724892(Gpsm1)

CPOC:

100712752(Gpsm1)

DORD:

105995666(Gpsm1)

DSP:	122108959(Gpsm1)

NCAR:

124964637

MMMA:

107159239(Gpsm1)

ITI:	101964221(Gpsm1)

OPI:	101535138(GPSM1)

TUP:	102494045(GPSM1)

GVR:	103590864(GPSM1)

CFA:	100855572(GPSM1)

CLUD:

112677436(GPSM1)

VVP:	112906948(GPSM1)

VLG:	121473710(GPSM1)

NPO:	129507644(GPSM1)

AML:	100467428(GPSM1)

UMR:	103675277(GPSM1)

UAH:	113266598(GPSM1)

UAR:	123796357(GPSM1)

ELK:

111146434

LLV:

125083031

MPUF:

101680378(GPSM1)

MNP:	132024250(GPSM1)

MLK:	131813191(GPSM1)

NVS:	122917123(GPSM1)

ORO:	101382753(GPSM1)

EJU:	114201885(GPSM1) 114203843 114203845

ZCA:	113934989(GPSM1)

MLX:	118017526(GPSM1)

NSU:	110581219(GPSM1)

LWW:	102742423(GPSM1)

FCA:	101088790(GPSM1)

PYU:	121022860(GPSM1)

PCOO:

112860478

PBG:	122475339(GPSM1)

PVIV:

125150772(GPSM1)

LRUF:

124522406

LGF:	123592636(GPSM1)

AJU:

106989555

PPAD:

109258800(GPSM1)

PUC:

125923315

PLEZ:

122205177(GPSM1)

HHV:	120221957(GPSM1)

BTA:	100139799(GPSM1)

BOM:	102276231(GPSM1)

BIU:	109565679(GPSM1)

BBUB:

102411854(GPSM1)

BBIS:

104988682

CHX:

102190425

OAS:	101116818(GPSM1)

BTAX:

128055986(GPSM1)

CSUM:

138079210(GPSM1)

ODA:	120852144(GPSM1)

CCAD:

122442323(GPSM1)

MREE:

136163628(GPSM1)

OVR:	110134080(GPSM1)

MBEZ:

129539484(GPSM1)

SSC:	110258076(GPSM1)

CFR:	102514671(GPSM1)

CBAI:

105069733(GPSM1)

CDK:	105106022(GPSM1)

VPC:	102537368(GPSM1)

BACU:

103018828(GPSM1)

BMUS:

118897164(GPSM1)

LVE:	103069666(GPSM1)

OOR:	101285058(GPSM1)

LALB:

132523175(GPSM1)

DLE:	111177035(GPSM1)

PCAD:

102983817

PSIU:

116755752(GPSM1)

NASI:

112411517(GPSM1)

ECB:	100066325(GPSM1)

EPZ:	103565347(GPSM1)

EAI:	106845552(GPSM1)

MMYO:

118655261(GPSM1)

MDT:	132212582(GPSM1)

MYUM:

139020619(GPSM1)

PKL:	118707015(GPSM1)

EFUS:

103295983(GPSM1)

MNA:	107535525(GPSM1)

DRO:	112306564(GPSM1)

SHON:

118980135(GPSM1)

AJM:	119036113(GPSM1)

PDIC:

114499571(GPSM1)

PHAS:

123823542(GPSM1)

MMF:	118629919(GPSM1)

PPAM:

129079554(GPSM1)

HAI:	109381429(GPSM1)

RFQ:	117031981(GPSM1)

PALE:

102885025(GPSM1)

PGIG:

120599724(GPSM1)

PVP:	105298581(GPSM1)

RAY:	107514873(GPSM1)

MJV:	108387658(GPSM1)

TOD:	119231121(GPSM1)

SARA:

101551318(GPSM1)

SFUM:

130040851(GPSM1)

SETR:

126009244(GPSM1)

LAV:	100658641(GPSM1)

TMU:

101361306

ETF:	101650802(GPSM1)

DNM:	101416981(GPSM1)

MDO:	100020642(GPSM1)

GAS:	123233614(GPSM1)

SHR:	100931535(GPSM1)

AFZ:

127550986

PCW:	110205336(GPSM1)

TVP:	118843971(GPSM1)

PBRV:

138147035(GPSM1)

OAA:	107548064(GPSM1)

TACU:

119927251(GPSM1)

GGA:	417132(GPSM1)

PCOC:

116234334(GPSM1)

MGP:	100547235(GPSM1)

CJO:	107321708(GPSM1)

TPAI:

128073106(GPSM1)

LMUT:

125702451(GPSM1)

NMEL:

110406834(GPSM1)

APLA:

101790352(GPSM1)

ACYG:

106040698(GPSM1)

CATA:

118252217(GPSM1)

AFUL:

116496981(GPSM1)

TGU:	100228863(GPSM1)

SCAN:

103818948(GPSM1)

PMOA:

120512432(GPSM1)

OTC:	121337076(GPSM1)

PRUF:

121362406(GPSM1)

ATRC:

139603277(GPSM1)

FAB:	101815873(GPSM1)

OMA:	130260157(GPSM1)

PHI:	102113272(GPSM1)

PMAJ:

107212091(GPSM1)

CCW:	104688357(GPSM1)

CBRC:

103623120(GPSM1)

ACOE:

138119582(GPSM1)

ETL:	114059113(GPSM1)

ZAB:	102067748(GPSM1)

ZLE:	135454840(GPSM1)

ACHL:

103804917(GPSM1)

SVG:	106855423(GPSM1)

MMEA:

130582255(GPSM1)

HRT:	120761675(GPSM1)

SATI:

136369813(GPSM1)

CCIC:

134051607(GPSM1)

FPG:	101910562(GPSM1)

FCH:	102046839(GPSM1)

CCRI:

104159818

NNT:

104409011

SHAB:

115616985(GPSM1)

ACUN:

113486524(GPSM1)

TALA:

104364277(GPSM1)

ACHC:

115335450(GPSM1)

HALD:

104318719

HLE:	104833839(GPSM1)

AGEN:

126051988

HHAR:

128154169(GPSM1)

GCL:

127023856

CSTI:

104555713(GPSM1)

LDI:

104346028

MNB:

103771869

DPUB:

104306538(GPSM1)

PPUS:

135190227(GPSM1)

AVIT:

104278860(GPSM1)

BRHI:

104500249

EGZ:	104129371(GPSM1)

NNI:	104023209(GPSM1)

PCRI:

104029628(GPSM1)

PCAO:

104043200

PADL:

103915250(GPSM1)

AFOR:

103900032(GPSM1)

FGA:

104083281

GSTE:

104261645

CLV:	102084935(GPSM1)

MUI:	104543550(GPSM1)

PGUU:

104466282(GPSM1)

PLET:

104617209(GPSM1)

EHS:

104515182

CMAC:

104485601

CUCA:

104066843(GPSM1)

TEO:	104374987(GPSM1)

BREG:

104633091 104638839

OHA:	104336604(GPSM1)

ACAR:

104523103

CPEA:

104389892(GPSM1)

CVF:	104292836(GPSM1)

RTD:	128917329(GPSM1)

CRID:

134523753(GPSM1)

AAM:	106487006(GPSM1)

AROW:

112964350(GPSM1)

TGT:	104575205(GPSM1)

DNE:	112979894(GPSM1)

SCAM:

104138222(GPSM1)

ASN:	102380609(GPSM1)

AMJ:	102572628(GPSM1)

CPOO:

109314019(GPSM1)

GGN:	109292753(GPSM1)

CMY:	102931915(GPSM1)

CCAY:

125623292(GPSM1)

DCC:	119844113(GPSM1)

CPIC:

101939280(GPSM1)

TST:	117889357(GPSM1)

CABI:

116817439(GPSM1)

MRV:	120387013(GPSM1)

ASAO:

132763735(GPSM1)

SUND:

121936270(GPSM1)

CTIG:

120317509(GPSM1)

PGUT:

117671279(GPSM1) 132709957

APRI:

131186294(GPSM1)

PTEX:

113448441(GPSM1)

NSS:	113427504(GPSM1)

VKO:	123035149(GPSM1)

PMUA:

114589095(GPSM1)

PRAF:

128406380(GPSM1)

ZVI:	118083973(GPSM1) 118088504

HCG:	128339037(GPSM1)

GJA:	107115407(GPSM1)

STOW:

125441664(GPSM1)

EMC:	129341932(GPSM1)

XLA:	108699905 446656(gpsm1.L)

XTR:	100125000(gpsm1)

NPR:	108793118(GPSM1)

RTEM:

120913846(GPSM1)

BBUF:

120977079(GPSM1)

BGAR:

122946494(GPSM1)

PWL:	138301304(GPSM1)

MUO:	115473024(GPSM1)

GSH:	117368505(GPSM1)

DRE:	493623(gpsm1b)

SRX:	107741501 107744057

SANH:

107674924 107704761

SGH:	107562333 107597941

CCAR:

109073947 122145107

CAUA:

113068065(gpsm1) 113086758

CGIB:

127957236 127989490

PTET:

122344876(gpsm1b)

LROH:

127165806(gpsm1b)

OMC:	131540356(gpsm1b)

PPRM:

120471898(gpsm1b)

RKG:	130089437(gpsm1b)

MAMB:

125267873(gpsm1b)

CIDE:

127512027

CERY:

137034288(gpsm1b)

MASI:

127426139 127435688

TROS:

130567421(gpsm1b)

TDW:	130419468(gpsm1b)

MANU:

129440772(gpsm1b)

PDAB:

135774110(gpsm1b)

IPU:	108260141(gpsm1b)

IFU:	128603784(gpsm1b)

PHYP:

113531092(gpsm1)

SMEO:

124378965(gpsm1b)

TFD:	113650883(gpsm1b)

TVC:	132840910(gpsm1b)

CGAR:

128512234(gpsm1b)

NGRA:

132875373(gpsm1b)

TRN:	134302992(gpsm1b)

AMEX:

103029351(gpsm1b)

CMAO:

118814841(gpsm1b)

EEE:	113587247(gpsm1)

CHAR:

105888486(gpsm1b)

SPIL:

134100837(gpsm1b)

TRU:	101071035(gpsm1)

TFS:	130516984(gpsm1b)

TNG:	GSTEN00034674G001

LCO:	104924179(gpsm1)

NCC:	104961829(gpsm1)

TBEN:

117476423(gpsm1b)

CGOB:

115016448(gpsm1)

PGEO:

117455841(gpsm1b)

GACU:

117539093(gpsm1b)

EMAC:

134868344(gpsm1b)

ELY:	117270021(gpsm1b)

EFO:	125906142(gpsm1b)

PLEP:

121959831(gpsm1b)

SLUC:

116062890(gpsm1b)

ECRA:

117959799(gpsm1b)

ESP:	116704434(gpsm1)

PFLV:

114570828

GAT:	120831596(gpsm1b)

PPUG:

119226828(gpsm1b)

AFB:	129102219(gpsm1b)

CLUM:

117740629(gpsm1b)

PSWI:

130205344(gpsm1b)

CANA:

137784144(gpsm1b)

CVE:	137869123(gpsm1b)

MSAM:

119914296(gpsm1b)

SCHU:

122865513(gpsm1b)

CUD:	121525093(gpsm1b)

SPUL:

138601990(gpsm1b)

LMIX:

132991983(gpsm1b)

ALAT:

119030233(gpsm1b)

ASTR:

137608332(gpsm1b)

MZE:	101485436(gpsm1)

ONL:	100696478(gpsm1)

OAU:	116331748(gpsm1b)

OLA:	101171349(gpsm1)

OML:	112162757(gpsm1b)

CSAI:

133454905(gpsm1b)

XMA:	102236604(gpsm1)

XCO:	114149352(gpsm1)

XHE:	116724966(gpsm1)

PRET:

103473842(gpsm1)

PFOR:

103142773 103142777

PLAI:

106942185 106961641(gpsm1)

PMEI:

106910217 106911279

GAF:	122819658(gpsm1b)

PPRL:

129366542(gpsm1b)

CVG:	107096157(gpsm1)

CTUL:

119789815(gpsm1b)

GMU:	124872681(gpsm1b)

NFU:	107374662(gpsm1)

KMR:	108230865(gpsm1b)

ALIM:

106518213(gpsm1)

NWH:	119424782(gpsm1b)

AOCE:

111577480(gpsm1b)

EJA:	138211483(gpsm1b)

BFRE:

138628034(gpsm1b)

MCEP:

124996842(gpsm1b)

CSEM:

103390193

POV:	109626431(gpsm1)

SSEN:

122758126(gpsm1b)

SSOE:

131446094(gpsm1b)

HHIP:

117771627(gpsm1b)

HSP:	118125743(gpsm1b)

PPLT:

128424873(gpsm1b)

SMAU:

118284811(gpsm1b)

LCF:	108874101(gpsm1b)

SDU:	111238511(gpsm1)

SLAL:

111664798(gpsm1)

XGL:	120806329(gpsm1b)

HCQ:	109528231(gpsm1)

SSCV:

125979609(gpsm1b)

SBIA:

133491123(gpsm1b)

PEE:	133413956(gpsm1b)

PTAO:

133490046(gpsm1b)

BPEC:

110160549(gpsm1)

ENY:	140366923(gpsm1b)

MALB:

109960618

BSPL:

114866879(gpsm1b)

SJO:	128380495(gpsm1b)

SSCO:

133995368(gpsm1b)

SASA:

106563264 106565740

STRU:

115159538 115204095

OTW:	112219330 112231016

OMY:	110509822 110523609

OGO:	124006983 124048938

ONE:	115101187 115123094

OKI:	109874129 109876021

OKE:	118385277 118387547

OMM:	135517957 135544446

OCLA:

139387772 139408664

SALP:

111961588 111964046

SNH:	120021255 120026185

CCLU:

121541692 121582483

ELS:	105015117(gpsm1)

OEP:	134038967(gpsm1b)

SFM:

108938607

AANG:

118206476 118212712(gpsm1b)

AROT:

135238985(gpsm1b) 135265189

CCOG:

133140698 133142194(gpsm1b)

LOC:	102694250(gpsm1)

PSPA:

121303561 121307066

ARUT:

117397001(gpsm1b)

PSEX:

120535087(gpsm1b)

RTP:	109916058(gpsm1b)

CPLA:

122564954(gpsm1b)

HOC:	132825917(gpsm1b)

LERI:

PMEO:

DPOL:

HSY:

Reference

PMID:10559191

Authors

Takesono A, Cismowski MJ, Ribas C, Bernard M, Chung P, Hazard S 3rd, Duzic E, Lanier SM

Title

Receptor-independent activators of heterotrimeric G-protein signaling pathways.

Journal

J Biol Chem 274:33202-5 (1999)
DOI:10.1074/jbc.274.47.33202

Sequence

[rno:246254]

Reference

PMID:20700046

Authors

Bowers MS

Title

Activators of G-protein signaling 3: a drug addiction molecular gateway.

Journal

Behav Pharmacol 21:500-13 (2010)
DOI:10.1097/FBP.0b013e32833dcfa5

Reference

PMID:15207906

Authors

Lanier SM

Title

AGS proteins, GPR motifs and the signals processed by heterotrimeric G proteins.

Journal

Biol Cell 96:369-72 (2004)
DOI:10.1016/j.biolcel.2004.03.012

LinkDB

DBGET integrated database retrieval system