KEGG   ORTHOLOGY: K15884
Entry
K15884            Tight     KO                                     
Symbol
snoaE, aknE1
Name
bifunctional aromatase (cyclase/dehydratase) [EC:4.2.1.-]
Pathway
map01056  Biosynthesis of type II polyketide backbone
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00778  Type II polyketide backbone biosynthesis, acyl-CoA + malonyl-CoA => polyketide
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01056 Biosynthesis of type II polyketide backbone
    K15884  snoaE, aknE1; bifunctional aromatase (cyclase/dehydratase)
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K15884  snoaE, aknE1; bifunctional aromatase (cyclase/dehydratase)
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.-
     K15884  snoaE, aknE1; bifunctional aromatase (cyclase/dehydratase)
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Type II PKS
   C7-C14 cyclized polyketide type
    Decaketide PKS
     K15884  snoaE, aknE1; bifunctional aromatase (cyclase/dehydratase)
Other DBs
RN: R09266 R09267
Genes
SGAL: CP966_29055
AG: AAA65203(dpsF) AAF70103(aknE1) CAA12012(snoaE)
Reference
PMID:8668120
  Authors
Ylihonko K, Tuikkanen J, Jussila S, Cong L, Mantsala P
  Title
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.
  Journal
Mol Gen Genet 251:113-20 (1996)
DOI:10.1007/BF02172908
  Sequence
[ag:CAA12012]
Reference
PMID:12137949
  Authors
Raty K, Kantola J, Hautala A, Hakala J, Ylihonko K, Mantsala P
  Title
Cloning and characterization of Streptomyces galilaeus aclacinomycins polyketide synthase (PKS) cluster.
  Journal
Gene 293:115-22 (2002)
DOI:10.1016/S0378-1119(02)00699-6
  Sequence
[ag:AAF70103]
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