KEGG   ORTHOLOGY: K15942
Entry
K15942                      KO                                     
Symbol
snoaC, dnrC, dauC, aknG
Name
O-methyltransferase / aklanonic acid methyltransferase [EC:2.1.1.- 2.1.1.288]
Pathway
map01057  Biosynthesis of type II polyketide products
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00781  Nogalavinone/aklavinone biosynthesis, deoxynogalonate/deoxyaklanonate => nogalavinone/aklavinone
Reaction
R06675  S-adenosyl-L-methionine:nogalonic-acid O-methyltransferase
R06680  S-adenosyl-L-methionine:aklanonate O-methyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01057 Biosynthesis of type II polyketide products
    K15942  snoaC, dnrC, dauC, aknG; O-methyltransferase / aklanonic acid methyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K15942  snoaC, dnrC, dauC, aknG; O-methyltransferase / aklanonic acid methyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.1  Transferring one-carbon groups
   2.1.1  Methyltransferases
    2.1.1.288  aklanonic acid methyltransferase
     K15942  snoaC, dnrC, dauC, aknG; O-methyltransferase / aklanonic acid methyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Methylase
   K15942  snoaC, dnrC, dauC, aknG; O-methyltransferase / aklanonic acid methyltransferase
Genes
SPRI: SPRI_0206
STIR: DDW44_27905
SKA: CP970_39700
SGAL: CP966_29095
SCIN: CP977_27945
STSU: B7R87_22120
SCOE: CP976_32895
SPEU: CGZ69_24295
SXN: IAG42_36855
SDD: D9753_08655
SJN: RI060_18400
SHAU: K9S39_40770
SKG: KJK29_16200
TALX: FOF52_07515
PMAD: BAY61_07665
MAU: Micau_3998
MIL: ML5_4423
MFEU: H1D33_25555
DACT: KZZ52_34380
AG: AAA65210(dnrC) AAB16936(dauC) AAF70111(aknG) CAA12014(snoaC)
 » show all
Reference
PMID:7836284
  Authors
Dickens ML, Ye J, Strohl WR
  Title
Analysis of clustered genes encoding both early and late steps in daunomycin biosynthesis by Streptomyces sp. strain C5.
  Journal
J Bacteriol 177:536-43 (1995)
DOI:10.1128/JB.177.3.536-543.1995
  Sequence
[ag:AAB16936]
Reference
PMID:8668120
  Authors
Ylihonko K, Tuikkanen J, Jussila S, Cong L, Mantsala P
  Title
A gene cluster involved in nogalamycin biosynthesis from Streptomyces nogalater: sequence analysis and complementation of early-block mutations in the anthracycline pathway.
  Journal
Mol Gen Genet 251:113-20 (1996)
DOI:10.1007/BF02172908
  Sequence
[ag:CAA12014]
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