ORTHOLOGY: K15963
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Entry
K15963 Tight KO
Symbol
mtmMII
Name
C-methyltransferase [EC:2.1.1.-]
Pathway
map01057
Biosynthesis of type II polyketide products
map01100
Metabolic pathways
map01110
Biosynthesis of secondary metabolites
Module
M00782
Mithramycin biosynthesis, 4-demethylpremithramycinone => mithramycin
Brite
KEGG Orthology (KO) [BR:
ko00001
]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01057 Biosynthesis of type II polyketide products
K15963 mtmMII; C-methyltransferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K15963 mtmMII; C-methyltransferase
Enzymes [BR:
ko01000
]
2. Transferases
2.1 Transferring one-carbon groups
2.1.1 Methyltransferases
2.1.1.-
K15963 mtmMII; C-methyltransferase
Polyketide biosynthesis proteins [BR:
ko01008
]
Polyketide tailoring proteins
Methylase
K15963 mtmMII; C-methyltransferase
BRITE hierarchy
Other DBs
RN:
R06719
Genes
AG:
CAK50790
(mtmMII)
Taxonomy
UniProt
Reference
PMID:
10652287
Authors
Lozano MJ, Remsing LL, Quiros LM, Brana AF, Fernandez E, Sanchez C, Mendez C, Rohr J, Salas JA
Title
Characterization of two polyketide methyltransferases involved in the biosynthesis of the antitumor drug mithramycin by Streptomyces argillaceus.
Journal
J Biol Chem 275:3065-74 (2000)
DOI:
10.1074/jbc.275.5.3065
Sequence
[ag:
CAK50790
]
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