KEGG   ORTHOLOGY: K15993
Entry
K15993            Tight     KO                                     
Symbol
tylN
Name
O-mycaminosyltylonolide 6-deoxyallosyltransferase [EC:2.4.1.317]
Pathway
map00522  Biosynthesis of 12-, 14- and 16-membered macrolides
map01052  Type I polyketide structures
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00773  Tylosin biosynthesis, methylmalonyl-CoA + malonyl-CoA => tylactone => tylosin
Reaction
R06451  dTDP-6-deoxy-alpha-D-allose:5-O-beta-D-mycaminosyltylonolide 23-O-6-deoxy-beta-D-allosyltransferase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K15993  tylN; O-mycaminosyltylonolide 6-deoxyallosyltransferase
   00522 Biosynthesis of 12-, 14- and 16-membered macrolides
    K15993  tylN; O-mycaminosyltylonolide 6-deoxyallosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K15993  tylN; O-mycaminosyltylonolide 6-deoxyallosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.1  Hexosyltransferases
    2.4.1.317  O-mycaminosyltylonolide 6-deoxyallosyltransferase
     K15993  tylN; O-mycaminosyltylonolide 6-deoxyallosyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Glycosyltransferase
   K15993  tylN; O-mycaminosyltylonolide 6-deoxyallosyltransferase
Other DBs
CAZy: GT1
Genes
AG: CAA06512(tylN)
Reference
  Authors
Rawlings BJ.
  Title
Type I polyketide biosynthesis in bacteria (part B).
  Journal
Nat Prod Rep 18:231-81 (2001)
DOI:10.1039/B100191O
Reference
PMID:9651492
  Authors
Wilson VT, Cundliffe E
  Title
Characterization and targeted disruption of a glycosyltransferase gene in the tylosin producer, Streptomyces fradiae.
  Journal
Gene 214:95-100 (1998)
DOI:10.1016/S0378-1119(98)00210-8
  Sequence
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