Entry |
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Symbol |
desVII
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Name |
narbonolide/10-deoxymethynolide desosaminyltransferase [EC: 2.4.1.277]
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Pathway |
map00522 | Biosynthesis of 12-, 14- and 16-membered macrolides |
map01110 | Biosynthesis of secondary metabolites |
|
Module |
M00776 | Pikromycin/methymycin biosynthesis, methylmalonyl-CoA + malonyl-CoA => narbonolide/10-deoxymethynolide => pikromycin/methymycin |
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Reaction |
R06460 | dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose:10-deoxymethynolide 3-dimethylamino-4,6-dideoxy-alpha-D-glucosyltransferase |
R06461 | dTDP-3-dimethylamino-3,4,6-trideoxy-alpha-D-glucopyranose:narbonolide 3-dimethylamino-4,6-dideoxy-alpha-D-glucosyltransferase |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
K16004 desVII; narbonolide/10-deoxymethynolide desosaminyltransferase
00522 Biosynthesis of 12-, 14- and 16-membered macrolides
K16004 desVII; narbonolide/10-deoxymethynolide desosaminyltransferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K16004 desVII; narbonolide/10-deoxymethynolide desosaminyltransferase
Enzymes [BR:ko01000]
2. Transferases
2.4 Glycosyltransferases
2.4.1 Hexosyltransferases
2.4.1.277 10-deoxymethynolide desosaminyltransferase
K16004 desVII; narbonolide/10-deoxymethynolide desosaminyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
Glycosyltransferase
K16004 desVII; narbonolide/10-deoxymethynolide desosaminyltransferase
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Other DBs |
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Genes |
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Reference |
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Authors |
Xue Y, Zhao L, Liu HW, Sherman DH |
Title |
A gene cluster for macrolide antibiotic biosynthesis in Streptomyces venezuelae: architecture of metabolic diversity. |
Journal |
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Sequence |
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Reference |
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Authors |
Borisova SA, Liu HW |
Title |
Characterization of glycosyltransferase DesVII and its auxiliary partner protein DesVIII in the methymycin/picromycin biosynthetic pathway. |
Journal |
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Sequence |
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LinkDB |
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