KEGG ORTHOLOGY: K16026

ORTHOLOGY: K16026

Entry

K16026                      KO

Symbol

asm15

Name

methoxymalonate biosynthesis protein

Pathway

map01051

Biosynthesis of ansamycins

map01052

Type I polyketide structures

Brite

KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16026  asm15; methoxymalonate biosynthesis protein
   01051 Biosynthesis of ansamycins
    K16026  asm15; methoxymalonate biosynthesis protein
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16026  asm15; methoxymalonate biosynthesis protein
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
  Others
   K16026  asm15; methoxymalonate biosynthesis protein

Genes

MBAI:

MB901379_02749(Acd_1)

NTP:	CRH09_20590

SGRF:

SGFS_005680 SGFS_014220

SCB:	SCAB_83961

SVL:	Strvi_5874 Strvi_6779

SRC:	M271_37840 M271_50135

SMAL:

SMALA_0862 SMALA_1270

SSOI:

I1A49_00855 I1A49_07815 I1A49_09835

SBH:	SBI_09656(ozmD)

SCW:	TU94_03080 TU94_30690

SAMB:

SAM23877_5602(srm35)

SCZ:	ABE83_03040

SLE:	sle_62770(sle_62770)

STRT:

A8713_28285

SCLF:

BB341_27680

SGS:	AVL59_10145

SAUO:

BV401_01105 BV401_08125 BV401_10135

SSIA:

A7J05_02375

SALJ:

SMD11_1672

SGD:	ELQ87_38740

SQZ:	FQU76_00585 FQU76_32220

SKA:	CP970_02195

SCAV:

CVT27_30485

SRIM:

CP984_12645

SSUB:

CP968_05705

STSU:

B7R87_00475 B7R87_01720 B7R87_31520

SGX:	H4W23_35900

SSPB:

CP982_14315

SHK:	J2N69_35940

SCAE:

IHE65_08970

SANT:

QR300_33405

SJN:	RI060_20865

SOV:	QZH56_33500

KSK:	KSE_73510(bfmD)

KAB:	B7C62_33100

KIS:	HUT16_05330 HUT16_33220

STRH:

GXP74_17970 GXP74_23580

NAKE:

KGD83_23285

SAIU:

J4H86_01035

AMAZ:

LUW76_46590

SACC:

EYD13_07700(acd) EYD13_10140(acrC1)

AMD:

AMN:

AMM:

AMZ:

AMYB:

AORI:

APRT:

APRE:

AMI:	Amir_3187 Amir_3281

SESP:

BN6_35420

SSYI:

EKG83_24520

KUT:	JJ691_23700

KPHY:

AOZ06_39680

ACTI:

UA75_16775

ACTA:

C1701_25710

UME:	RM788_50580

MTUA:

MICH:

MCAB:

ACTN:

ACTR:

PLK:	CIK06_12135

PSUU:

Psuf_000470

» show all

Reference

PMID:17076505

Authors

Wenzel SC, Williamson RM, Grunanger C, Xu J, Gerth K, Martinez RA, Moss SJ, Carroll BJ, Grond S, Unkefer CJ, Muller R, Floss HG

Title

On the biosynthetic origin of methoxymalonyl-acyl carrier protein, the substrate for incorporation of "glycolate" units into ansamitocin and soraphen A.

Journal

J Am Chem Soc 128:14325-36 (2006)
DOI:10.1021/ja064408t

Reference

PMID:12060743

Authors

Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG

Title

The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.

Journal

Proc Natl Acad Sci U S A 99:7968-73 (2002)
DOI:10.1073/pnas.092697199

Sequence

[apre:CNX65_16215]

LinkDB

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