Entry |
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Symbol |
asm21
|
Name |
7-O-carbamoyltransferase [EC:2.1.3.-]
|
Pathway |
map01110 | Biosynthesis of secondary metabolites |
|
Reaction |
R09853 | carbamoyl-phosphate:20-O-methyl-19-chloroproansamitocin carbamoyltransferase |
R09858 | carbamoyl-phosphate:ansamitocinoside-P-3 carbamoyltransferase |
|
Brite |
KEGG Orthology (KO) [BR:ko00001]
09100 Metabolism
09109 Metabolism of terpenoids and polyketides
01052 Type I polyketide structures
K16035 asm21; 7-O-carbamoyltransferase
01051 Biosynthesis of ansamycins
K16035 asm21; 7-O-carbamoyltransferase
09180 Brite Hierarchies
09181 Protein families: metabolism
01008 Polyketide biosynthesis proteins
K16035 asm21; 7-O-carbamoyltransferase
Polyketide biosynthesis proteins [BR:ko01008]
Polyketide tailoring proteins
Others
K16035 asm21; 7-O-carbamoyltransferase
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Genes |
|
Reference |
|
Authors |
Li Y, Zhao P, Kang Q, Ma J, Bai L, Deng Z |
Title |
Dual carbamoylations on the polyketide and glycosyl moiety by asm21 result in extended ansamitocin biosynthesis. |
Journal |
|
Reference |
|
Authors |
Spiteller P, Bai L, Shang G, Carroll BJ, Yu TW, Floss HG |
Title |
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum. |
Journal |
|
Reference |
|
Authors |
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG |
Title |
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum. |
Journal |
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Sequence |
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LinkDB |
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