KEGG   ORTHOLOGY: K16037
Entry
K16037            Tight     KO                                     
Symbol
asm11
Name
4,5-epoxidase
Pathway
map01051  Biosynthesis of ansamycins
map01052  Type I polyketide structures
map01110  Biosynthesis of secondary metabolites
Reaction
R09855  
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16037  asm11; 4,5-epoxidase
   01051 Biosynthesis of ansamycins
    K16037  asm11; 4,5-epoxidase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16037  asm11; 4,5-epoxidase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Others
   K16037  asm11; 4,5-epoxidase
Genes
APRE: CNX65_16195
AMI: Amir_3183
Reference
  Authors
Spiteller P, Bai L, Shang G, Carroll BJ, Yu TW, Floss HG
  Title
The post-polyketide synthase modification steps in the biosynthesis of the antitumor agent ansamitocin by Actinosynnema pretiosum.
  Journal
J Am Chem Soc 125:14236-7 (2003)
DOI:10.1021/ja038166y
Reference
  Authors
Yu TW, Bai L, Clade D, Hoffmann D, Toelzer S, Trinh KQ, Xu J, Moss SJ, Leistner E, Floss HG
  Title
The biosynthetic gene cluster of the maytansinoid antitumor agent ansamitocin from Actinosynnema pretiosum.
  Journal
Proc Natl Acad Sci U S A 99:7968-73 (2002)
DOI:10.1073/pnas.092697199
  Sequence
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