KEGG   ORTHOLOGY: K16046
Entry
K16046                      KO                                     
Symbol
CYP142
Name
cholest-4-en-3-one 26-monooxygenase [EC:1.14.15.28]
Pathway
map00984  Steroid degradation
map01120  Microbial metabolism in diverse environments
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09111 Xenobiotics biodegradation and metabolism
   00984 Steroid degradation
    K16046  CYP142; cholest-4-en-3-one 26-monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K16046  CYP142; cholest-4-en-3-one 26-monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.15  With reduced iron-sulfur protein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.15.28  cholest-4-en-3-one 26-monooxygenase [(25R)-3-oxocholest-4-en-26-oate forming]
     K16046  CYP142; cholest-4-en-3-one 26-monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, bacteria type
  CYP142 family
   K16046  CYP142; cholest-4-en-3-one 26-monooxygenase
Other DBs
RN: R11358 R11359 R11360 R11361
COG: COG2124
Genes
MTU: Rv3518c(cyp142)
MTV: RVBD_3518c
MTC: MT3619
MRA: MRA_3557(cyp142)
MTF: TBFG_13551
MTB: TBMG_03557
MTK: TBSG_03584
MTZ: TBXG_003533
MTG: MRGA327_21740
MTI: MRGA423_22200
MTUR: CFBS_3734(cyp142)
MTO: MTCTRI2_3582(cyp142)
MTD: UDA_3518c(cyp142)
MTN: ERDMAN_3857(cyp142)
MTUC: J113_24605
MTUE: J114_18810
MTUH: I917_24680
MTUL: TBHG_03458
MTUT: HKBT1_3719(cyp142)
MTUU: HKBT2_3728(cyp142)
MTQ: HKBS1_3731(cyp142)
MBO: BQ2027_MB3547C(cyp142b) BQ2027_MB3548C(cyp142a)
MBB: BCG_3581c(cyp142b) BCG_3582c(cyp142a)
MBT: JTY_3582(cyp142b) JTY_3583(cyp142a)
MBM: BCGMEX_3579c(cyp142b) BCGMEX_3580c(cyp142a)
MBX: BCGT_3381
MCE: MCAN_35291(cyp142)
MCQ: BN44_110006(cyp)
MCV: BN43_90011(cyp)
MCX: BN42_90009(cyp)
MCZ: BN45_100009(cyp)
MPA: MAP_0547
MAO: MAP4_3320
MAVI: RC58_16465
MAVU: RE97_16500
MAV: MAV_0641
MLP: MLM_0784
MMAN: MMAN_43780(cyp142) MMAN_48470
MUL: MUL_4077(cyp142A3)
MMC: Mmcs_4631
MKM: Mkms_4719
MJL: Mjls_5013
MMI: MMAR_5003(cyp142A3)
MMAE: MMARE11_48130(cyp142A3)
MLI: MULP_05251(cyp142A3)
MHAD: B586_04705
MSHG: MSG_04505(cyp142)
MFJ: MFLOJ_41190(cyp142)
MSTO: MSTO_45170(cyp142)
MSIM: MSIM_29590(cyp142) MSIM_48400
MSAK: MSAS_28600
MXE: MYXE_06290(cyp142)
MNV: MNVI_12010(cyp142)
MCOO: MCOO_26630(cyp142)
MSEO: MSEO_33990(cyp142)
MPSE: MPSD_52010(cyp142)
MSHO: MSHO_04690(cyp142)
MHEK: JMUB5695_00528(cyp142)
MGAU: MGALJ_37780(cyp142)
MLJ: MLAC_00250(cyp142)
MBRD: MBRA_14020(cyp142) MBRA_20550
MSHJ: MSHI_39220(cyp142)
MKR: MKOR_35990(cyp142)
MSG: MSMEI_5758(cyp142)
MVA: Mvan_5217
MGI: Mflv_1541
MVQ: MYVA_5103
MHAS: MHAS_03703
MMAG: MMAD_47780
MMOR: MMOR_12480(cyp142_2)
MALV: MALV_43030
MARZ: MARA_48660
MGAD: MGAD_36860(cyp142)
MHEV: MHEL_08790(cyp142) MHEL_28410
MAUB: MAUB_26100
MPOF: MPOR_53180
MPHU: MPHO_44250
MBOK: MBOE_03720
MCEE: MCEL_38510(cyp142)
MJD: JDM601_3652(cyp142A3)
MTER: 4434518_03626(cyp142A3)
MMIN: MMIN_11820
MHIB: MHIB_30500
RER: RER_07670
REY: O5Y_03730
ROP: ROP_45330
REQ: REQ_06880
TCU: Tcur_2583
SRO: Sros_7155
 » show all
Reference
PMID:20843794 (CYP142A1)
  Authors
Johnston JB, Ouellet H, Ortiz de Montellano PR
  Title
Functional redundancy of steroid C26-monooxygenase activity in Mycobacterium tuberculosis revealed by biochemical and genetic analyses.
  Journal
J Biol Chem 285:36352-60 (2010)
DOI:10.1074/jbc.M110.161117
  Sequence
[mtu:Rv3518c]
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