KEGG ORTHOLOGY: K16220

ORTHOLOGY: K16220

Entry

K16220                      KO

Symbol

HAX1

Name

HCLS1-associated protein X-1

Disease

H00100

Neutropenic disorders

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03019 Messenger RNA biogenesis
    K16220  HAX1; HCLS1-associated protein X-1
Messenger RNA biogenesis [BR:ko03019]
Eukaryotic type
  mRNA surveillance and transport factors
   Factors involved in mRNA localization
    Trans-acting binding proteins
     K16220  HAX1; HCLS1-associated protein X-1

Genes

HSA:	10456(HAX1)

PTR:	457347(HAX1)

PPS:	100974655(HAX1)

GGO:	101123788(HAX1)

PON:	100461420(HAX1)

NLE:	100580185 100604949(HAX1)

HMH:	116469366(HAX1)

MCC:	716495(HAX1)

MCF:	102119274(HAX1)

MTHB:

126934435

MNI:	105497969(HAX1)

CSAB:

103223927(HAX1)

CATY:

105593491(HAX1)

PANU:

101023324 116269740(HAX1) 116273205

TGE:	112626723(HAX1)

MLEU:

105554064(HAX1)

RRO:	104663498(HAX1)

RBB:	108526633(HAX1)

TFN:	117077429(HAX1)

PTEH:

111543720(HAX1)

CANG:

105502001(HAX1)

CJC:	100414479(HAX1)

SBQ:	101028586(HAX1) 101036853

CIMI:

108292446(HAX1)

CSYR:

103250673 103262880(HAX1)

MMUR:

105885909(HAX1)

LCAT:

123634020(HAX1)

PCOQ:

105821791(HAX1)

OGA:	100948644(HAX1)

MMU:	23897(Hax1)

MCAL:

110290733(Hax1)

MPAH:

110320291(Hax1)

RNO:	291202(Hax1)

MCOC:

116093193(Hax1)

ANU:	117706672(Hax1)

MUN:	110554254(Hax1)

CGE:	100761361(Hax1)

MAUA:

101844144(Hax1)

PROB:

127223983 127232757(Hax1)

PLEU:

114689791 114707954(Hax1)

MORG:

121450789(Hax1)

MFOT:

126516094

AAMP:

119801471(Hax1) 119825462

NGI:	103751396(Hax1)

HGL:	101726528(Hax1)

CPOC:

100731401(Hax1)

CCAN:

109687986(Hax1)

DORD:

105984783(Hax1)

DSP:	122109364(Hax1)

PLOP:

125359974(Hax1)

NCAR:

124992596

MMMA:

107156750(Hax1)

OCU:

100348155

OPI:	101527068(HAX1)

TUP:	102487073(HAX1)

GVR:	103608075(HAX1)

CFA:	480134(HAX1)

CLUD:

112647733(HAX1)

VVP:	112918881(HAX1)

VLG:	121483257 121484887(HAX1)

NPO:	129497782 129508877(HAX1) 129517948

AML:	100481604(HAX1)

UMR:	103668400(HAX1)

UAH:	113245316(HAX1)

UAR:	123783215(HAX1)

ELK:

111138898

LLV:

125085656

MPUF:

101672909(HAX1)

MNP:	132025937(HAX1)

MLK:	131814968(HAX1)

NVS:	122918231(HAX1)

ORO:	101375945(HAX1)

EJU:	114198726(HAX1)

ZCA:	113932693(HAX1)

MLX:	118013847(HAX1)

NSU:	110573498(HAX1)

FCA:	101097787(HAX1)

PYU:	121015676(HAX1)

PBG:	122476463(HAX1)

PVIV:

125155183(HAX1)

LRUF:

124521770

PTG:	102951878(HAX1)

PPAD:

109256279(HAX1)

PUC:

125925745

AJU:

106987235

HHV:	120221485(HAX1)

BTA:	506895(HAX1)

BOM:	102286292(HAX1)

BIU:	109554308(HAX1)

BBUB:

102409986(HAX1)

BBIS:

104987436(HAX1)

CHX:	102174791(HAX1)

OAS:	101111760(HAX1)

BTAX:

128045041(HAX1)

ODA:	120855770(HAX1)

CCAD:

122433207(HAX1)

MBEZ:

129541830(HAX1)

SSC:	100739544(HAX1)

CFR:	102521621(HAX1)

CBAI:

105068185(HAX1)

CDK:	105089164(HAX1)

VPC:	102529190(HAX1)

BACU:

102997412(HAX1)

BMUS:

118879960(HAX1)

LVE:	103079312(HAX1)

OOR:	101280540(HAX1)

DLE:	111167193(HAX1)

PCAD:

102993879(HAX1)

PSIU:

116763664(HAX1)

NASI:

112401796(HAX1)

ECB:	100056899(HAX1)

EPZ:	103555410(HAX1)

EAI:	106846238(HAX1)

MYB:	102240230(HAX1)

MYD:	102753090(HAX1)

MMYO:

118673454(HAX1)

MLF:	102435038(HAX1)

PKL:	118721124(HAX1)

EFUS:

103298923(HAX1)

MNA:	107543899(HAX1)

DRO:	112314298(HAX1)

SHON:

118990192(HAX1)

AJM:	119061815(HAX1)

PDIC:

114489169(HAX1)

PHAS:

123804460(HAX1)

MMF:	118637315(HAX1)

PPAM:

129062365(HAX1)

HAI:	109373502(HAX1)

RFQ:	117014722(HAX1)

PALE:

102896388(HAX1)

PGIG:

120592163(HAX1)

PVP:	105296386(HAX1)

RAY:	107509344(HAX1)

MJV:	108394097(HAX1)

TOD:	119236516(HAX1)

SARA:

101551869(HAX1)

SETR:

126007092 126020796(HAX1)

LAV:	100663628(HAX1)

TMU:

101361474

ETF:	101657663(HAX1)

DNM:	101418136(HAX1)

MDO:	100015562(HAX1)

GAS:	123244210(HAX1)

SHR:	100918638(HAX1)

AFZ:

127559862

PCW:	110211984(HAX1)

OAA:	100089567(HAX1)

GGA:	107055138(HAX1)

PCOC:

116237316(HAX1)

CJO:	107324498(HAX1)

TPAI:

128073503(HAX1)

LMUT:

125685701(HAX1)

NMEL:

110387961(HAX1)

APLA:

113840043(HAX1)

CATA:

118258459(HAX1) 118260686

AFUL:

116499690(HAX1) 116499749

TGU:	100227885(HAX1)

LSR:	110471583(HAX1)

SCAN:

103823965(HAX1)

PMOA:

120498900(HAX1)

OTC:	121332167(HAX1)

PRUF:

121352189(HAX1)

GFR:	102037798(HAX1)

FAB:	101820700(HAX1)

OMA:	130263203(HAX1)

PHI:	102100882(HAX1)

PMAJ:

107214560(HAX1)

CCAE:

111939460(HAX1)

CBRC:

103611315(HAX1)

ETL:	114068444(HAX1)

ZAB:	113460303(HAX1)

SVG:	106863370(HAX1)

MMEA:

130583202(HAX1)

HRT:	120764277(HAX1)

FPG:	101924615(HAX1)

FCH:	102050672(HAX1)

CLV:	110364231(HAX1)

EGZ:	104123079(HAX1)

NNI:	104012294(HAX1)

PLET:

104618231(HAX1)

TALA:

116960517(HAX1)

AFOR:

103902346(HAX1)

ACHC:

115346553(HAX1)

HLE:	104829732(HAX1)

AGEN:

126040501

SHAB:

115602580(HAX1)

CPEA:

104390613(HAX1)

CVF:	104292247(HAX1)

RTD:	128900864(HAX1)

CUCA:

104061400(HAX1)

BRHI:

104497545(HAX1)

AROW:

112973218(HAX1)

DNE:	112994389(HAX1)

ASN:	102371674(HAX1)

AMJ:	102570010(HAX1)

GGN:	109304128(HAX1)

CMY:	102948001(HAX1)

CCAY:

125625771(HAX1)

DCC:	119847723(HAX1)

CPIC:

101938403(HAX1)

TST:	117889125(HAX1)

CABI:

116832745(HAX1)

MRV:	120390738(HAX1)

ASAO:

132764098(HAX1) 132772537

PVT:	110088475(HAX1)

SUND:

121915460(HAX1)

PBI:	103058146(HAX1)

PMUR:

107285209(HAX1)

CTIG:

120317155(HAX1)

PGUT:

117657388 117658971

APRI:

131186738(HAX1)

PTEX:

113452544 113452548

VKO:	123032512(HAX1)

PMUA:

114587189(HAX1)

PRAF:

128403704(HAX1)

ZVI:	118075646(HAX1)

HCG:	128336919(HAX1)

GJA:	107117094(HAX1)

STOW:

125444220(HAX1)

EMC:	129344795(HAX1)

XLA:	379170(hax1.L)

XTR:	100485912(hax1)

NPR:	108799655(HAX1)

RTEM:

120920451(HAX1)

BBUF:

120981876(HAX1)

MUO:	115458302(HAX1)

GSH:	117349946(HAX1)

DRE:	436609(hax1)

SRX:	107729882 107753511

SANH:

107670002 107693320

SGH:	107589419 107599494

CCAR:

109052776 109052824 109064519

CAUA:

113062211

CGIB:

127935865 127978992

PTET:

122323591(hax1)

LROH:

127181385(hax1)

OMC:	131525762(hax1)

PPRM:

120483799(hax1)

RKG:	130102348(hax1)

MAMB:

125275731(hax1)

CIDE:

127500718

MASI:

127421010

TROS:

130567468(hax1)

TDW:	130415600(hax1)

MANU:

129456070(hax1)

IPU:

108272649

IFU:	128616216(hax1)

PHYP:

113535346(hax1)

SMEO:

124381789(hax1)

TFD:	113647938(hax1)

AMEX:

103033207(hax1)

CMAO:

118805957(hax1)

EEE:	113572572(hax1)

CHAR:

105901450(hax1)

TRU:	101075529(hax1)

TFS:	130518799(hax1)

LCO:	104927549(hax1)

NCC:	104944818(hax1)

TBEN:

117478452(hax1)

CGOB:

115015723(hax1)

PGEO:

117455120(hax1)

GACU:

117542583(hax1)

EMAC:

134874909(hax1)

ELY:	117263393(hax1)

EFO:	125905283(hax1)

PLEP:

121957707 121965755

SLUC:

116047341(hax1)

ECRA:

117957062(hax1)

ESP:	116701680(hax1)

PFLV:

114568178(hax1)

GAT:	120826684(hax1)

PPUG:

119218805(hax1)

AFB:	129097497(hax1)

CLUM:

117739394(hax1)

PSWI:

130193151(hax1)

MSAM:

119907820(hax1)

SCHU:

122864888(hax1)

CUD:	121523272(hax1)

ALAT:

119016591(hax1)

MZE:	101478479(hax1)

ONL:	100711405(hax1)

OAU:	116320000(hax1)

OLA:	111948168(hax1)

OML:	112142144 112162648(hax1)

CSAI:

133461403(hax1)

XMA:	102229050(hax1)

XCO:	114156634(hax1)

XHE:	116731421(hax1)

PRET:

103472715(hax1)

PFOR:

103130962(hax1)

PLAI:

106959168(hax1)

PMEI:

106919968(hax1)

GAF:	122843089(hax1)

PPRL:

129374946(hax1)

CVG:	107101122(hax1)

CTUL:

119779663(hax1)

GMU:	124878699(hax1)

NFU:	107394649(hax1)

KMR:	108238727(hax1)

ALIM:

106528311(hax1)

NWH:	119425246(hax1)

AOCE:

111562515(hax1)

MCEP:

125019988(hax1)

CSEM:

103394539(hax1)

POV:	109638806(hax1)

SSEN:

122786944(hax1)

HHIP:

117770598(hax1)

HSP:	118124783(hax1)

SMAU:

118291699(hax1)

LCF:

108888870

SDU:	111223543(hax1)

SLAL:

111657641(hax1)

XGL:	120786905(hax1)

HCQ:	109514606(hax1)

SSCV:

125987267

SBIA:

133499644(hax1)

PEE:	133396113(hax1)

PTAO:

133471298(hax1)

BPEC:

110167199(hax1)

MALB:

109973923(hax1)

BSPL:

114866270(hax1)

SJO:	128373793(hax1)

SASA:

100194877(hax1)

STRU:

115173266(hax1)

OTW:	112266618(hax1)

OMY:

110495990

OGO:

124012552

ONE:	115128190(hax1)

OKI:	109907709(hax1)

OKE:

118399092

SALP:

111955692(hax1)

SNH:	120022264(hax1)

CCLU:

121586293(hax1)

ELS:	105008613(hax1)

SFM:	108926571(hax1)

PKI:	111839648(hax1)

AANG:

118232741(hax1)

LOC:	102692246(hax1)

PSPA:

121309840(hax1)

ARUT:

117395572 117971847

PSEX:

120527973(hax1)

LCM:	102359499(HAX1)

CPLA:

122544750

HOC:	132805555(hax1)

PMRN:

116940311(HAX1)

LRJ:	133346695(HAX1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

SKO:

AME:

ALAB:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPYO:

BPAS:

CCAL:

OBB:

MGEN:

CGIG:

SOC:

MPHA:

AEC:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

MDL:

CGLO:

FAS:

DAM:

CCIN:

AROA:

TCA:

DPA:

SOY:

CSET:

AGB:

LDC:	111517134 111517135

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_210712

BANY:

PPOT:

PXU:

PRAP:

ZCE:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105384373 105386001

BTAB:

CLEC:

HHAL:

NLU:

ZNE:

CSEC:

BROR:

PVM:

PJA:

HAME:

PCLA:

CQD:

PTRU:

HAZT:

PPOI:

DSV:	119442143 119442235

RSAN:

RMP:

CSCU:

PTEP:

SDM:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

LAK:	106158078 106161946

NVE:	116608288 5503433

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:	114520473 114531315

XEN:

124433784

» show all

Reference

PMID:21391832

Authors

Simmen T

Title

Hax-1: a regulator of calcium signaling and apoptosis progression with multiple roles in human disease.

Journal

Expert Opin Ther Targets 15:741-51 (2011)
DOI:10.1517/14728222.2011.561787

Reference

PMID:21302289

Authors

Yap SV, Koontz JM, Kontrogianni-Konstantopoulos A

Title

HAX-1: a family of apoptotic regulators in health and disease.

Journal

J Cell Physiol 226:2752-61 (2011)
DOI:10.1002/jcp.22638

Reference

PMID:15159385

Authors

Ortiz DF, Moseley J, Calderon G, Swift AL, Li S, Arias IM

Title

Identification of HAX-1 as a protein that binds bile salt export protein and regulates its abundance in the apical membrane of Madin-Darby canine kidney cells.

Journal

J Biol Chem 279:32761-70 (2004)
DOI:10.1074/jbc.M404337200

Sequence

[rno:291202]

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