KEGG   ORTHOLOGY: K16339
Entry
K16339                      KO                                     
Symbol
THEM4, CTMP
Name
acyl-coenzyme A thioesterase THEM4 [EC:3.1.2.2]
Pathway
map00062  Fatty acid elongation
map01110  Biosynthesis of secondary metabolites
map04151  PI3K-Akt signaling pathway
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09103 Lipid metabolism
   00062 Fatty acid elongation
    K16339  THEM4, CTMP; acyl-coenzyme A thioesterase THEM4
 09130 Environmental Information Processing
  09132 Signal transduction
   04151 PI3K-Akt signaling pathway
    K16339  THEM4, CTMP; acyl-coenzyme A thioesterase THEM4
Enzymes [BR:ko01000]
 3. Hydrolases
  3.1  Acting on ester bonds
   3.1.2  Thioester hydrolases
    3.1.2.2  palmitoyl-CoA hydrolase
     K16339  THEM4, CTMP; acyl-coenzyme A thioesterase THEM4
Other DBs
RN: R09450
GO: 0016290
Genes
HSA: 117145(THEM4)
PTR: 457305(THEM4)
PPS: 100969253 100981869(THEM4)
GGO: 101140561(THEM4)
PON: 100440874(THEM4)
NLE: 100600341(THEM4)
MCC: 711796(THEM4)
MCF: 102145205(THEM4)
CSAB: 103224017
CATY: 105590243(THEM4)
PANU: 101012893(THEM4)
TGE: 112631666(THEM4)
RRO: 104681026(THEM4)
RBB: 108533212(THEM4)
TFN: 117074346 117074518(THEM4)
PTEH: 111543666(THEM4)
CJC: 100400243(THEM4)
SBQ: 101034294(THEM4)
CSYR: 103263778(THEM4)
MMUR: 105873055(THEM4)
LCAT: 123635133(THEM4)
OGA: 100964729(THEM4)
MMU: 75778(Them4)
MCAL: 110291876(Them4)
MPAH: 110320649(Them4)
RNO: 361992(Them4)
MCOC: 116093361(Them4)
MUN: 110565679(Them4)
CGE: 100769809(Them4)
MAUA: 106022699(Them4) 121138567
PLEU: 114683214(Them4)
MORG: 121437929 121450787
AAMP: 119801433(Them4)
NGI: 103730047(Them4)
HGL: 101703857(Them4)
CPOC: 100721204(Them4)
CCAN: 109696693(Them4)
DORD: 105984736(Them4)
DSP: 122109437(Them4)
NCAR: 124959162
OCU: 100339997(THEM4) 103348628
OPI: 101535621(THEM4)
TUP: 102482524(THEM4)
CFA: 609163(THEM4)
VVP: 112907787(THEM4)
VLG: 121491214(THEM4)
AML: 100471932(THEM4)
UMR: 103667498(THEM4)
UAH: 113246173(THEM4)
UAR: 123787693(THEM4)
ELK: 111162045
LLV: 125098334
MPUF: 101677035(THEM4)
ORO: 101365923(THEM4)
EJU: 114197336(THEM4)
ZCA: 113927968(THEM4)
MLX: 118000360(THEM4)
FCA: 101084812(THEM4)
PYU: 121021085(THEM4)
PBG: 122481187(THEM4)
PTG: 102968396(THEM4)
PPAD: 109257030(THEM4)
AJU: 106979970(THEM4)
HHV: 120241207(THEM4)
BTA: 787270(THEM4)
BOM: 102279271(THEM4)
BIU: 109554812(THEM4)
BBUB: 102392814(THEM4)
CHX: 102190188(THEM4)
OAS: 101119606(THEM4)
ODA: 120855860(THEM4)
CCAD: 122434847(THEM4)
CFR: 102507666(THEM4)
CBAI: 105071701(THEM4)
CDK: 105103232(THEM4)
VPC: 102536142(THEM4)
BACU: 103002195(THEM4)
LVE: 103091662(THEM4)
OOR: 101285149(THEM4)
DLE: 111169719(THEM4)
PCAD: 102987336(THEM4)
PSIU: 116739888(THEM4)
ECB: 100055681(THEM4)
EPZ: 103547926(THEM4)
EAI: 106848358(THEM4)
MYB: 102245884 102249483 102254099
MYD: 102762592(THEM4)
MMYO: 118673388(THEM4)
MLF: 102417517(THEM4) 102427328
MNA: 107540780(THEM4)
PKL: 118727290(THEM4)
HAI: 109374393(THEM4)
DRO: 112316018(THEM4)
SHON: 118996801(THEM4)
AJM: 119048123(THEM4)
PDIC: 114489007(THEM4)
PHAS: 123804296(THEM4)
MMF: 118637684(THEM4)
RFQ: 117015148(THEM4) 117019794
PALE: 102897248(THEM4)
PGIG: 120616858
PVP: 105303852(THEM4)
RAY: 107500640(THEM4)
TOD: 119236868 119236869
SARA: 101548074(THEM4)
LAV: 100671841(THEM4)
TMU: 101360029
DNM: 101414191
OAA: 100081588
GGA: 100858223(THEM4)
PCOC: 116238432
MGP: 104915960
CJO: 107324587
NMEL: 110387810
APLA: 113841471
AFUL: 116499717
OTC: 121338556
PRUF: 121360148
GFR: 106632128
PHI: 102106344(THEM4)
CCAE: 111943895
CLV: 102096765(THEM4)
ACHC: 115345946
AAM: 106492217(THEM4)
AROW: 112974558
DNE: 112981972(THEM4)
ASN: 102388313 102388555
AMJ: 102559435(THEM4) 109281033
CPOO: 109324823(THEM4)
PSS: 102461711(THEM4)
CMY: 102930379
CPIC: 101935735
TST: 117869640
CABI: 116817640
MRV: 120390654
ACS: 100564032(them4)
PVT: 110081520 110081550
SUND: 121916218
PBI: 103051027(THEM4) 103053373
PMUR: 107285192 107285193 107285194
TSR: 106543935 106543944
PGUT: 117676287 117676290
VKO: 123032941 123032942
PMUA: 114586840(THEM4)
ZVI: 118076540
GJA: 107126254 107126255 107126260 107126262
STOW: 125436620 125439233
XLA: 443715(them4.L)
XTR: 101735170
NPR: 108797700(THEM4)
RTEM: 120920402 120920404 120920405 120920406 120920407
BBUF: 120982040 120982263
BGAR: 122921918
DRE: 791152(them4)
SRX: 107749198
SANH: 107684185
SGH: 107596683
CCAR: 109066376 109105736
CAUA: 113059639 113069342 113116219
PPRM: 120495045(them4)
MAMB: 125243411(them4)
PHYP: 113533692
SMEO: 124385248(them4)
TFD: 113644170(them4)
AMEX: 103035109
EEE: 113575243
TRU: 101064761
TNG: GSTEN00033986G001
LCO: 104923063
NCC: 104959154
CGOB: 115021369
ELY: 117266078(them4)
PLEP: 121945200(them4)
SLUC: 116049522(them4)
ECRA: 117946378(them4)
PFLV: 114557733
GAT: 120810648(them4)
PPUG: 119197839(them4)
MSAM: 119897620(them4)
CUD: 121513201(them4)
ALAT: 119005335(them4)
MZE: 101466288
ONL: 100702377
OAU: 116315660(them4)
OLA: 101172604
OML: 112143157(them4)
XMA: 102232383
XCO: 114142257
XHE: 116717066
PRET: 103478140
PFOR: 103140893
PLAI: 106937890
PMEI: 106916281
GAF: 122831227(them4)
CVG: 107096308
CTUL: 119786686(them4)
GMU: 124864046(them4)
NFU: 107379750
KMR: 108241061(them4)
ALIM: 106533283
NWH: 119410049(them4)
AOCE: 111582981
POV: 109633040(them4)
SSEN: 122774205(them4)
HHIP: 117776660(them4)
HSP: 118114312(them4)
LCF: 108889573
SDU: 111237209
SLAL: 111650907
XGL: 120783706(them4)
HCQ: 109529029
BPEC: 110163137
MALB: 109964143
BSPL: 114843489(them4)
SASA: 106575342 106592246
OTW: 121841044
OMY: 110508333(them4)
OGO: 124017014
ONE: 115118970 115121675
SALP: 111964813
SNH: 120048794(them4)
ELS: 105029233
SFM: 108924938
PKI: 111838445
AANG: 118219718(them4)
LOC: 102691049
PSPA: 121309833(them4)
ARUT: 117395476 117969132
BFO: 118408394 118412648
BBEL: 109486495
SPU: 753049
APLC: 110986239 110990476 110990477 110990478 110990479 110990480
SKO: 102808799
NVE: 5511206
EPA: 110243130 110243139
ATEN: 116299934
AMIL: 114959498
PDAM: 113681596
SPIS: 111321718
DGT: 114529409 114529410
HMG: 100214723 100214744 101238603 105843122
TAD: TRIADDRAFT_52537
MPP: MICPUCDRAFT_58619
GSL: Gasu_32340 Gasu_46590
MGR: MGG_10034
BFU: BCIN_11g01860
PNO: SNOG_08299
PTE: PTT_15054
BOR: COCMIDRAFT_90983
ACAN: ACA1_235040
TET: TTHERM_00310740
PTM: GSPATT00003881001 GSPATT00015164001 GSPATT00020511001
NGD: NGA_0706200
SPAR: SPRG_04086
NGR: NAEGRDRAFT_79845
 » show all
Reference
PMID:11598301
  Authors
Maira SM, Galetic I, Brazil DP, Kaech S, Ingley E, Thelen M, Hemmings BA
  Title
Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane.
  Journal
Science 294:374-80 (2001)
DOI:10.1126/science.1062030
  Sequence
[hsa:117145]
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