KEGG   ORTHOLOGY: K16380
Entry
K16380                      KO                                     
Symbol
rapN
Name
cytochrome P450 RapN
Pathway
map01052  Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16380  rapN; cytochrome P450 RapN
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16380  rapN; cytochrome P450 RapN
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Oxygenase
   K16380  rapN; cytochrome P450 RapN
Genes
NYA: LTV02_14130
SRC: M271_40670
AMYE: MJQ72_01000(nmvG)
KUT: JJ691_58020
KBR: Q4V65_16070
AAUR: V5P93_005067
ACTN: L083_2958(rapN)
AG: CAA60465(rapN)
Reference
PMID:7644502
  Authors
Schwecke T, Aparicio JF, Molnar I, Konig A, Khaw LE, Haydock SF, Oliynyk M, Caffrey P, Cortes J, Lester JB, et al.
  Title
The biosynthetic gene cluster for the polyketide immunosuppressant rapamycin.
  Journal
Proc Natl Acad Sci U S A 92:7839-43 (1995)
DOI:10.1073/pnas.92.17.7839
Reference
PMID:8635730
  Authors
Molnar I, Aparicio JF, Haydock SF, Khaw LE, Schwecke T, Konig A, Staunton J, Leadlay PF
  Title
Organisation of the biosynthetic gene cluster for rapamycin in Streptomyces hygroscopicus: analysis of genes flanking the polyketide synthase.
  Journal
Gene 169:1-7 (1996)
DOI:10.1016/0378-1119(95)00799-7
  Sequence
[ag:CAA60465]
Reference
PMID:11372782
  Authors
Chung L, Liu L, Patel S, Carney JR, Reeves CD
  Title
Deletion of rapQONML from the rapamycin gene cluster of Streptomyces hygroscopicus gives production of the 16-O-desmethyl-27-desmethoxy analog.
  Journal
J Antibiot (Tokyo) 54:250-6 (2001)
DOI:10.7164/antibiotics.54.250
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