KEGG   ORTHOLOGY: K16387
Entry
K16387                      KO                                     
Symbol
amphK, nysK
Name
polyene macrolide polyketide synthase
Pathway
map01052  Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16387  amphK, nysK; polyene macrolide polyketide synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16387  amphK, nysK; polyene macrolide polyketide synthase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   cis-AT PKS
    Polyene macrolide PKS
     K16387  amphK, nysK; polyene macrolide polyketide synthase
Genes
STRE: GZL_00799
SNR: SNOUR_03800
SALL: SAZ_40885
SNQ: CP978_03050
SYUN: MOV08_03315
PSEQ: AD006_18015
PECQ: AD017_25855
AG: AAF71768(nysK) AAK73503(amphK)
Reference
PMID:11451671 (amphK)
  Authors
Caffrey P, Lynch S, Flood E, Finnan S, Oliynyk M
  Title
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.
  Journal
Chem Biol 8:713-23 (2001)
DOI:10.1016/S1074-5521(01)00046-1
  Sequence
Reference
PMID:10873841 (nysK)
  Authors
Brautaset T, Sekurova ON, Sletta H, Ellingsen TE, StrLm AR, Valla S, Zotchev SB
  Title
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.
  Journal
Chem Biol 7:395-403 (2000)
DOI:10.1016/S1074-5521(00)00120-4
  Sequence
LinkDB

DBGET integrated database retrieval system