KEGG   ORTHOLOGY: K16390
Entry
K16390                      KO                                     
Symbol
amphL, nysL, pimD
Name
cytochrome P450 monooxygenase
Pathway
map01052  Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16390  amphL, nysL, pimD; cytochrome P450 monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16390  amphL, nysL, pimD; cytochrome P450 monooxygenase
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide tailoring proteins
  Oxygenase
   K16390  amphL, nysL, pimD; cytochrome P450 monooxygenase
Genes
STRE: GZL_00798
SLD: T261_7938
SNR: SNOUR_03795
SALU: DC74_1404 DC74_7919
SALL: SAZ_07555 SAZ_40890
SGV: B1H19_05075
SALJ: SMD11_6570(penM)
SNQ: CP978_03045
SPAD: DVK44_33975
SCHA: CP983_04160
SCYG: S1361_34255(penM)
AMYY: YIM_39555(penM)
PSEA: WY02_00355
PSEH: XF36_05070
PHH: AFB00_29715(selL)
AG: AAF71769(nysL) AAK73504(amphL) CAC20932(pimD)
 » show all
Reference
PMID:11451671 (amphL)
  Authors
Caffrey P, Lynch S, Flood E, Finnan S, Oliynyk M
  Title
Amphotericin biosynthesis in Streptomyces nodosus: deductions from analysis of polyketide synthase and late genes.
  Journal
Chem Biol 8:713-23 (2001)
DOI:10.1016/S1074-5521(01)00046-1
  Sequence
Reference
PMID:10873841 (nysL)
  Authors
Brautaset T, Sekurova ON, Sletta H, Ellingsen TE, StrLm AR, Valla S, Zotchev SB
  Title
Biosynthesis of the polyene antifungal antibiotic nystatin in Streptomyces noursei ATCC 11455: analysis of the gene cluster and deduction of the biosynthetic pathway.
  Journal
Chem Biol 7:395-403 (2000)
DOI:10.1016/S1074-5521(00)00120-4
  Sequence
Reference
PMID:11094342 (pimD)
  Authors
Aparicio JF, Fouces R, Mendes MV, Olivera N, Martin JF
  Title
A complex multienzyme system encoded by five polyketide synthase genes is involved in the biosynthesis of the 26-membered polyene macrolide pimaricin in Streptomyces natalensis.
  Journal
Chem Biol 7:895-905 (2000)
DOI:10.1016/S1074-5521(00)00038-7
  Sequence
LinkDB

DBGET integrated database retrieval system