KEGG   ORTHOLOGY: K16418
Entry
K16418                      KO                                     
Symbol
mlsA1
Name
mycolactone core lactone polyketide synthase MlsA1
Pathway
map01052  Type I polyketide structures
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   01052 Type I polyketide structures
    K16418  mlsA1; mycolactone core lactone polyketide synthase MlsA1
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01008 Polyketide biosynthesis proteins
    K16418  mlsA1; mycolactone core lactone polyketide synthase MlsA1
Polyketide biosynthesis proteins [BR:ko01008]
 Polyketide synthase (PKS)
  Modular type I PKS
   cis-AT PKS
    Mycolactone PKS
     K16418  mlsA1; mycolactone core lactone polyketide synthase MlsA1
Genes
MUL: MUP040c(mlsA1)
MLI: MULP_065(mlsA1)
Reference
PMID:14736915
  Authors
Stinear TP, Mve-Obiang A, Small PL, Frigui W, Pryor MJ, Brosch R, Jenkin GA, Johnson PD, Davies JK, Lee RE, Adusumilli S, Garnier T, Haydock SF, Leadlay PF, Cole ST
  Title
Giant plasmid-encoded polyketide synthases produce the macrolide toxin of Mycobacterium ulcerans.
  Journal
Proc Natl Acad Sci U S A 101:1345-9 (2004)
DOI:10.1073/pnas.0305877101
  Sequence
[mul:MUP040c]
Reference
PMID:18840298
  Authors
Pidot SJ, Hong H, Seemann T, Porter JL, Yip MJ, Men A, Johnson M, Wilson P, Davies JK, Leadlay PF, Stinear TP
  Title
Deciphering the genetic basis for polyketide variation among mycobacteria producing mycolactones.
  Journal
BMC Genomics 9:462 (2008)
DOI:10.1186/1471-2164-9-462
LinkDB

DBGET integrated database retrieval system