KEGG ORTHOLOGY: K16599

ORTHOLOGY: K16599

Entry

K16599                      KO

Symbol

TTLL1

Name

tubulin polyglutamylase TTLL1 [EC:6.3.2.61]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K16599  TTLL1; tubulin polyglutamylase TTLL1
   04812 Cytoskeleton proteins
    K16599  TTLL1; tubulin polyglutamylase TTLL1
Enzymes [BR:ko01000]
6. Ligases
  6.3  Forming carbon-nitrogen bonds
   6.3.2  Acid-D-amino-acid ligases (peptide synthases)
    6.3.2.61  tubulin-glutamate ligase
     K16599  TTLL1; tubulin polyglutamylase TTLL1
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  Tubulin polyglutamylase and associated proteins
   K16599  TTLL1; tubulin polyglutamylase TTLL1
Cytoskeleton proteins [BR:ko04812]
Eukaryotic cytoskeleton proteins
  Microtubules
   Tubulin-binding proteins
    Tubulin modification proteins
     Tubulin polyglutamylases
      K16599  TTLL1; tubulin polyglutamylase TTLL1
     Tubulin polyglutamylase complex components
      K16599  TTLL1; tubulin polyglutamylase TTLL1

Other DBs

GO:

0070740

Genes

HSA:	25809(TTLL1)

PTR:	458886(TTLL1)

PPS:	100991355(TTLL1)

GGO:	101153146(TTLL1)

PON:	100434512(TTLL1)

NLE:	100595841(TTLL1)

HMH:	116458684(TTLL1)

MCC:	714668(TTLL1)

MCF:	102130316(TTLL1)

MTHB:

126963607

MNI:	105464329(TTLL1)

CSAB:

103223433(TTLL1)

CATY:

105598328(TTLL1)

PANU:

101023657(TTLL1)

TGE:	112632957(TTLL1)

MLEU:

105542444(TTLL1)

RRO:	104668589(TTLL1)

RBB:	108513993(TTLL1)

TFN:	117096365(TTLL1)

PTEH:

111549120(TTLL1)

CANG:

105514033(TTLL1)

CJC:	100401316(TTLL1)

SBQ:	101053979(TTLL1)

CIMI:

108296435(TTLL1) 108298484

CSYR:

103265800(TTLL1)

MMUR:

105858623(TTLL1)

LCAT:

123640267(TTLL1)

PCOQ:

105805147(TTLL1)

OGA:	100950261(TTLL1)

MMU:	319953(Ttll1)

MCAL:

110310289(Ttll1)

MPAH:

110334839(Ttll1)

RNO:	362969(Ttll1)

MCOC:

116076951(Ttll1)

ANU:	117719327(Ttll1)

MUN:	110552074(Ttll1)

CGE:	100767980(Ttll1)

MAUA:

101823083(Ttll1)

PROB:

127225879(Ttll1)

PLEU:

114682759(Ttll1)

MORG:

121461312(Ttll1)

MFOT:

126493811

AAMP:

119823173(Ttll1)

NGI:	103743441(Ttll1)

HGL:	101717967(Ttll1)

CPOC:

100721988(Ttll1)

CCAN:

109693098(Ttll1)

DORD:

105992128(Ttll1)

DSP:	122123578(Ttll1)

PLOP:

125357384(Ttll1)

NCAR:

124983202

MMMA:

107155817(Ttll1)

OPI:	101532389(TTLL1)

TUP:	102471974(TTLL1)

GVR:	103596381(TTLL1)

CFA:	100855660(TTLL1)

CLUD:

112666436(TTLL1)

VVP:	112933971(TTLL1)

VLG:	121492015(TTLL1)

NPO:	129511515(TTLL1)

AML:	100474817(TTLL1)

UMR:	103674148(TTLL1)

UAH:	113241683(TTLL1)

UAR:	123780803(TTLL1)

ELK:

111157543

LLV:

125107484

MPUF:

101689580(TTLL1)

MNP:	132019144(TTLL1)

MLK:	131839580(TTLL1)

NVS:	122891734(TTLL1)

ORO:	101377477(TTLL1)

EJU:	114218420(TTLL1)

ZCA:	113922135(TTLL1)

MLX:	117998597(TTLL1)

NSU:	110569614 110578268(TTLL1)

LWW:	102744613(TTLL1)

FCA:	101086406(TTLL1)

PYU:	121040221(TTLL1)

PCOO:

112863421(TTLL1)

PBG:	122472863(TTLL1)

PVIV:

125170298(TTLL1)

LRUF:

124502546

PTG:	102967578(TTLL1)

PPAD:

109265676(TTLL1)

PUC:

125919667

AJU:

106967277

HHV:	120234953(TTLL1)

BTA:	539530(TTLL1)

BOM:	102285989(TTLL1)

BIU:	109559890(TTLL1)

BBUB:

102390762(TTLL1)

BBIS:

104991237(TTLL1)

CHX:	102190671(TTLL1)

OAS:	101116134(TTLL1)

BTAX:

128048298(TTLL1)

ODA:	120857560(TTLL1)

CCAD:

122422899 122423762(TTLL1)

MBEZ:

129536355(TTLL1)

SSC:	100621517(TTLL1)

CFR:	102514193(TTLL1)

CBAI:

105073044(TTLL1)

CDK:	105091868(TTLL1)

BACU:

103013303(TTLL1)

BMUS:

118902708(TTLL1)

LVE:	103091101(TTLL1)

OOR:	101276286(TTLL1)

DLE:	111186350(TTLL1)

PCAD:

102979239 102990482(TTLL1)

PSIU:

116760935(TTLL1)

NASI:

112394734(TTLL1)

ECB:	100056216(TTLL1)

EPZ:	103564656(TTLL1)

EAI:	106845940(TTLL1)

MYB:	102263265(TTLL1)

MYD:	102774527(TTLL1)

MMYO:

118651666(TTLL1)

MLF:	102423453(TTLL1)

PKL:	118712075(TTLL1)

EFUS:

103298626(TTLL1)

MNA:	107534957(TTLL1)

DRO:	112321835(TTLL1)

SHON:

118974938(TTLL1)

AJM:	119060571(TTLL1)

PDIC:

114513152(TTLL1)

PHAS:

123816160(TTLL1)

MMF:	118624660(TTLL1)

PPAM:

129077949(TTLL1)

HAI:	109371479(TTLL1)

RFQ:	117029359(TTLL1)

PALE:

102883745(TTLL1)

PGIG:

120602915(TTLL1)

PVP:	105298018(TTLL1)

RAY:	107505553(TTLL1)

MJV:	108410082(TTLL1)

TOD:	119247176(TTLL1)

SARA:

101548846(TTLL1)

SETR:

126006259(TTLL1)

LAV:	100654067(TTLL1)

TMU:

101344044

ETF:	101642544 101661064(TTLL1)

DNM:	101413460(TTLL1)

MDO:	100011528(TTLL1)

GAS:	123248618(TTLL1)

SHR:

100921544

AFZ:	127538465 127538466

PCW:	110205881(TTLL1)

OAA:	100076725(TTLL1)

GGA:	418225(TTLL1)

PCOC:

116231437(TTLL1)

MGP:	100542512(TTLL1)

CJO:	107317289(TTLL1)

TPAI:

128084515(TTLL1)

LMUT:

125703918(TTLL1)

NMEL:

110396688(TTLL1)

APLA:

101803736(TTLL1)

ACYG:

106038248(TTLL1)

CATA:

118245163(TTLL1)

AFUL:

116490451(TTLL1)

TGU:	100219185(TTLL1)

LSR:	110473179(TTLL1)

SCAN:

103819565(TTLL1)

PMOA:

120507366(TTLL1)

OTC:	121347854(TTLL1)

PRUF:

121351900(TTLL1)

GFR:	102042366(TTLL1)

FAB:	101818501(TTLL1)

OMA:	130248691(TTLL1)

PHI:	102101809(TTLL1)

PMAJ:

107204448(TTLL1)

CCAE:

111929373(TTLL1)

CCW:	104696132(TTLL1)

CBRC:

103623375(TTLL1)

ETL:	114068613(TTLL1)

ZAB:	102071256(TTLL1)

ACHL:

103801238(TTLL1)

SVG:	106856058(TTLL1)

MMEA:

130576142(TTLL1)

HRT:	120752316(TTLL1)

FPG:	101916264(TTLL1)

FCH:	102054485(TTLL1)

CLV:	102087228(TTLL1)

EGZ:	104135153(TTLL1)

NNI:	104012680(TTLL1)

PCRI:

104023729(TTLL1)

PLET:

104619100(TTLL1)

EHS:	104515942(TTLL1)

PCAO:

104052112

ACUN:

113487866(TTLL1)

TALA:

104368891(TTLL1)

PADL:

103924309(TTLL1)

AFOR:

103898711(TTLL1)

ACHC:

115352304(TTLL1)

HALD:

104322877(TTLL1)

HLE:	104829378(TTLL1)

AGEN:

126047734

GCL:

127029992

CCRI:

104162300(TTLL1)

CSTI:

104550085(TTLL1)

CMAC:

104479487(TTLL1)

MUI:	104539643(TTLL1)

BREG:

104635314(TTLL1)

FGA:

104075191

GSTE:

104259510(TTLL1)

LDI:	104339825(TTLL1)

MNB:	103770477(TTLL1)

OHA:	104327004(TTLL1)

NNT:	104409243(TTLL1)

SHAB:

115605532(TTLL1)

DPUB:

104296323(TTLL1)

PGUU:

104472335(TTLL1)

ACAR:

104523856(TTLL1)

CPEA:

104393478(TTLL1)

AVIT:

104279320

CVF:	104281665(TTLL1)

RTD:	128916510(TTLL1)

CUCA:

104067265(TTLL1)

TEO:

104379392

BRHI:

104497438(TTLL1)

AAM:	106488901(TTLL1)

AROW:

112967066(TTLL1)

NPD:	112960140(TTLL1)

TGT:	104568882(TTLL1)

DNE:	112991540(TTLL1)

SCAM:

104146646(TTLL1)

ASN:	102383070(TTLL1)

AMJ:	102570539(TTLL1)

CPOO:

109316358(TTLL1)

GGN:	109296330(TTLL1)

PSS:	102459960(TTLL1)

CMY:	102936953(TTLL1)

CCAY:

125624598(TTLL1)

DCC:	119858678(TTLL1)

CPIC:

101953522(TTLL1)

TST:	117883738(TTLL1)

CABI:

116814688(TTLL1)

MRV:	120406980(TTLL1)

ACS:	100553512(ttll1)

ASAO:

132776483(TTLL1)

PVT:	110087163(TTLL1)

SUND:

121932234(TTLL1)

PBI:	103048034(TTLL1)

PMUR:

107294334(TTLL1)

CTIG:

120307065(TTLL1)

TSR:

106549232

PGUT:

117679810(TTLL1)

APRI:

131201781(TTLL1)

PTEX:

113437654(TTLL1)

NSS:	113418645(TTLL1)

VKO:	123033934(TTLL1)

PMUA:

114596894(TTLL1)

PRAF:

128413564(TTLL1)

ZVI:	118096373(TTLL1)

HCG:	128326950(TTLL1)

GJA:	107120311(TTLL1)

STOW:

125435899(TTLL1)

EMC:	129343919(TTLL1)

XLA:	100036964(ttll1.S) 108710716(ttll1.L)

XTR:	100495095(ttll1)

NPR:	108784602(TTLL1)

RTEM:

120932949(TTLL1)

BBUF:

121006756(TTLL1)

BGAR:

122926465(TTLL1)

MUO:	115478146(TTLL1)

GSH:	117363930(TTLL1)

DRE:	393994(ttll1)

SRX:	107725792(ttll1)

SANH:

107656691(ttll1)

SGH:	107569114(ttll1)

CCAR:

109062592(ttll1)

CAUA:

113066467(ttll1)

CGIB:

127956164

PTET:

122343040(ttll1)

LROH:

127163888(ttll1)

OMC:	131539483(ttll1)

PPRM:

120478363

RKG:	130070018(ttll1)

MAMB:

125244521 125260712 125277592

CIDE:

127511159

MASI:

127435340

TROS:

130547670(ttll1)

TDW:	130420591(ttll1)

MANU:

129432723(ttll1)

IPU:

108279717

IFU:	128623506(ttll1)

PHYP:

113531760(ttll1)

SMEO:

124400970(ttll1)

TFD:	113645490(ttll1)

TVC:	132859348(ttll1)

AMEX:

103040554(ttll1)

CMAO:

118812416(ttll1)

EEE:	113573525(ttll1)

CHAR:

105900691(ttll1)

TRU:	101075034(ttll1)

TFS:	130519086(ttll1)

TNG:	GSTEN00021557G001

LCO:	104926733(ttll1)

NCC:	104950108(ttll1)

TBEN:

117485096(ttll1)

CGOB:

115028575(ttll1)

PGEO:

117439021(ttll1)

GACU:

117559201(ttll1)

EMAC:

134878908(ttll1)

ELY:	117249099(ttll1)

EFO:	125882703(ttll1)

PLEP:

121961437(ttll1)

SLUC:

116060159(ttll1)

ECRA:

117938938(ttll1)

ESP:	116673219(ttll1) 116675753

PFLV:

114550252(ttll1)

GAT:	120817676(ttll1)

PPUG:

119210362(ttll1)

AFB:	129112719(ttll1)

CLUM:

117726548(ttll1)

PSWI:

130200811(ttll1)

MSAM:

119918436(ttll1)

SCHU:

122871476(ttll1)

CUD:	121505559(ttll1)

ALAT:

119032351(ttll1)

MZE:	101474099(ttll1)

ONL:	100695389(ttll1)

OAU:	116334915(ttll1)

OLA:	101159875(ttll1)

OML:	112154014(ttll1)

CSAI:

133423942(ttll1)

XMA:	102233958(ttll1)

XCO:	114160842(ttll1)

XHE:	116736664(ttll1)

PRET:

103459185(ttll1)

PFOR:

103156931(ttll1)

PLAI:

106949781(ttll1)

PMEI:

106914477(ttll1)

GAF:	122826188(ttll1)

PPRL:

129375564(ttll1)

CVG:	107098894(ttll1)

CTUL:

119789325(ttll1)

GMU:	124883166(ttll1)

NFU:	107386059(ttll1)

KMR:	108233189(ttll1)

ALIM:

106514799(ttll1)

NWH:	119427988(ttll1)

AOCE:

111577420(ttll1)

MCEP:

124999722(ttll1)

CSEM:

103382693(ttll1)

POV:	109632787(ttll1)

SSEN:

122766707(ttll1)

HHIP:

117757554(ttll1)

HSP:	118101684(ttll1)

SMAU:

118291223(ttll1)

LCF:

108890225

SDU:	111224748(ttll1)

SLAL:

111656459(ttll1)

XGL:	120804259(ttll1)

HCQ:	109523651(ttll1)

SSCV:

125992127

SBIA:

133493685(ttll1)

PEE:	133396966(ttll1)

PTAO:

133471759(ttll1)

BPEC:

110161885(ttll1)

MALB:

109959897(ttll1)

BSPL:

114862143(ttll1)

SJO:	128353291(ttll1)

SASA:

100380708(ttl1) 106576374

STRU:

115180573 115199067

OTW:	112234239 112267811

OMY:	110490559(ttll1) 110501019

OGO:	123994393 124014052

ONE:	115132935 115132940

OKI:	109896553 116352954

OKE:	118366426 118392545

SALP:

111981626 112070835

SNH:	120050011(ttll1)

CCLU:

121543441 121549323

ELS:	105020407(ttll1)

SFM:	108942118(ttll1)

PKI:	111838514(ttll1)

AANG:

118231510(ttll1)

LOC:	102694222(ttll1)

PSPA:

121318447

ARUT:

117415019 117420114

LCM:	102362485(TTLL1)

CMK:	103179067(ttll1) 103181831

RTP:	109911650 109913932

CPLA:

122559375 122563273

HOC:	132824736 132828219

LERI:

129706117 129708612

PMRN:

116956451(TTLL1)

LRJ:	133360344(TTLL1)

BFO:

BBEL:

CIN:

SCLV:

SPU:

LPIC:

APLC:

SKO:	100375554(TTLL1)

DME:	Dmel_CG32238(TTLL1B)

DER:

6543954

DSE:

6610814

DSI:	Dsimw501_GD13857(Dsim_GD13857)

DYA:	Dyak_GE21463

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DMO:	Dmoj_GI12743

DAZ:

DNV:

DHE:

DVI:

CCAT:

BOD:

BDR:

RZE:

AOQ:

TDA:	119662179 119670792

MDE:

101888623

SCAC:

106083209

LCQ:

111675004

LSQ:	119610809 119615099

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AFUN:

AMOU:

AALI:

AAG:

AALB:

CQU:	CpipJ_CPIJ012875

CPII:

CNS:

BCOO:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BTER:

BAFF:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

PBAR:

VEM:

HST:

DQU:

CFO:

FEX:

LHU:

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:

CGLO:

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

AGB:

LDC:

NVL:

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

DPL:	KGM_209916

BANY:

112053927 112053928 112053933

MJU:	123871593 123872083

NIQ:	126770575 126770580 126770901

VCD:	124529803 124529954 124530012

MCIX:

123657238 123657239 123657512

PMAC:

PPOT:

PXU:

PRAP:

PBX:	123708341 123709038 123709039

PNAP:

125049741 125049749 125049751

ZCE:	119832490 119832572

CCRC:

123695481 123695482 123695667 123695806 123695808

LSIN:

126978476 126978477 126978479

AAGE:

121732378 121732691

HAW:	110376852 110377590

HZE:	124633089 124633372 124633457

TNL:

SLIU:

OFU:

PXY:

PGW:	126368722 126369128

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

126834283 126835858 126845724

DVT:	126895841 126896279 126903646

BTAB:

DCI:

CLEC:

HHAL:

NLU:

HVI:

MQU:

PHU:	Phum_PHUM364090

FOC:

TPAL:

ZNE:

CSEC:

SGRE:

BROR:

134541047 134541048 134541051

IEL:

124162879

FCD:

110844821

DPX:	DAPPUDRAFT_324141

DMK:

DPZ:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:	126994177 127000451

MNZ:

HAZT:

EAF:

LSM:

TCF:

PPOI:

DSV:

RSAN:

RMP:

VDE:

VJA:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

PMEO:

LGI:	LOTGIDRAFT_214949

PVUL:

PCAN:

BGT:

GAE:

HRF:

HRJ:

CRG:

CVN:

CANU:

OED:

MYI:

PMAX:

MCAF:

RPHI:

DPOL:

OBI:

OSN:

LAK:

SMM:	Smp_043920

SHX:	MS3_00002685(TTLL1)

OVI:	T265_10230

EGL:

NVE:

EPA:

ATEN:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

HSY:

TAD:	TRIADDRAFT_33013

AQU:

100631813

CRE:	CHLRE_02g117350v5

VCN:	VOLCADRAFT_66113(mot11)

MIS:	MICPUN_88360

MPP:	MICPUCDRAFT_3527(JGI:MicpuC2_3527)

MBR:	MONBRDRAFT_30326

SRE:	PTSG_05189

TET:	TTHERM_00136210

PTM:	GSPATT00018943001 GSPATT00024583001

AAF:	AURANDRAFT_33385

PIF:	PITG_08756

PSOJ:

PHYSODRAFT_304629

SPAR:

SPRG_13914 SPRG_15792

GTT:	GUITHDRAFT_66166

TBR:	Tb927.5.3860

TBG:	TbgDal_V5360

TCR:	506743.210 509253.20

LMA:	LMJF_16_0380

LIF:	LINJ_16_0390

LDO:	LDBPK_160390

LMI:	LMXM_16_0380

LBZ:	LBRM_16_0390

LPAN:

LPMP_160390

NGR:	NAEGRDRAFT_33283

GLA:	GL50803_0014498

» show all

Reference

PMID:15890843

Authors

Janke C, Rogowski K, Wloga D, Regnard C, Kajava AV, Strub JM, Temurak N, van Dijk J, Boucher D, van Dorsselaer A, Suryavanshi S, Gaertig J, Edde B

Title

Tubulin polyglutamylase enzymes are members of the TTL domain protein family.

Journal

Science 308:1758-62 (2005)
DOI:10.1126/science.1113010

Sequence

[mmu:319953]

Reference

PMID:11054573

Authors

Trichet V, Ruault M, Roizes G, De Sario A

Title

Characterization of the human tubulin tyrosine ligase-like 1 gene (TTLL1) mapping to 22q13.1.

Journal

Gene 257:109-17 (2000)
DOI:10.1016/S0378-1119(00)00383-8

Sequence

[hsa:25809]

LinkDB

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