KEGG   ORTHOLOGY: K16647
Entry
K16647                      KO                                     
Symbol
aftC
Name
arabinofuranan 3-O-arabinosyltransferase [EC:2.4.2.47]
Pathway
map00571  Lipoarabinomannan (LAM) biosynthesis
map00572  Arabinogalactan biosynthesis - Mycobacterium
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09107 Glycan biosynthesis and metabolism
   00571 Lipoarabinomannan (LAM) biosynthesis
    K16647  aftC; arabinofuranan 3-O-arabinosyltransferase
   00572 Arabinogalactan biosynthesis - Mycobacterium
    K16647  aftC; arabinofuranan 3-O-arabinosyltransferase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   01003 Glycosyltransferases
    K16647  aftC; arabinofuranan 3-O-arabinosyltransferase
Enzymes [BR:ko01000]
 2. Transferases
  2.4  Glycosyltransferases
   2.4.2  Pentosyltransferases
    2.4.2.47  arabinofuranan 3-O-arabinosyltransferase
     K16647  aftC; arabinofuranan 3-O-arabinosyltransferase
Glycosyltransferases [BR:ko01003]
 Polysaccharide
  Bacterial polysaccharide (excluding LPS)
   K16647  aftC; arabinofuranan 3-O-arabinosyltransferase
Genes
LJR: NCTC11533_01968
PPNO: DA70_07255
PPNM: LV28_23420
PRB: X636_19420
PSPU: NA29_19460
PFG: AB870_19545
PCAY: FRD00_08085
SIX: BSY16_1928
RHN: AMJ98_CH03635
REZ: AMJ99_CH03687
RHT: NT26_0804
RPD: RPD_2994
MTU: Rv2673(aftC)
MTV: RVBD_2673
MTC: MT2747
MRA: MRA_2701
MTUR: CFBS_2825
MTD: UDA_2673
MTUB: MT7199_2705(aftC)
MTUC: J113_18595
MTUE: J114_14270
MTUH: I917_18775
MTUL: TBHG_02609
MTUT: HKBT1_2816
MTUU: HKBT2_2819
MBO: BQ2027_MB2692(aftc)
MBB: BCG_2686
MBT: JTY_2680
MBX: BCGT_2505
MAF: MAF_26770
MMIC: RN08_2957
MLE: ML1338
MLB: MLBr01338
MPA: MAP_2793
MAO: MAP4_1019
MAVI: RC58_05015
MAVU: RE97_05010
MAV: MAV_3565
MIT: OCO_33990
MIA: OCU_34010
MID: MIP_05118
MYO: OEM_34370
MIR: OCQ_35210
MLP: MLM_1549
MMAN: MMAN_04000
MUL: MUL_3307
MMC: Mmcs_2217
MKM: Mkms_2263
MJL: Mjls_2206
MMI: MMAR_2043
MMM: W7S_17000
MHAD: B586_14375
MSHG: MSG_01857
MSTO: MSTO_15440
MSIM: MSIM_04740(aftC)
MSAK: MSAS_56580
MKU: I2456_10045(aftC)
MNV: MNVI_34640(aftC)
MCOO: MCOO_02790
MBAI: MB901379_01864(aftC)
MSEO: MSEO_06560
MPSE: MPSD_20690
MSHO: MSHO_51400(aftC)
MLJ: MLAC_26060(aftC)
MBRD: MBRA_44930(aftC)
MSHJ: MSHI_20300
MDF: K0O62_12535(aftC)
MMAM: K3U93_09070(aftC)
MHOL: K3U96_15375(aftC)
MHER: K3U94_13720(aftC)
MSEN: K3U95_10620(aftC)
MPAE: K0O64_11715(aftC)
MOT: LTS72_14510(aftC)
MLM: MLPF_1866(aftC)
MVM: MJO54_13870(aftC)
MRF: MJO55_11205(aftC)
MPAA: MKK62_14995(aftC)
MCRO: MI149_12580(aftC)
MVA: Mvan_2488
MGI: Mflv_3915
MVQ: MYVA_2378
MHAS: MHAS_02308(aftC)
MMAG: MMAD_23810
MMOR: MMOR_39690
MAIC: MAIC_21020
MALV: MALV_12200
MARZ: MARA_15870
MGAD: MGAD_14410
MHEV: MHEL_45970
MSAR: MSAR_33900
MANY: MANY_07510
MAUB: MAUB_57060
MPOF: MPOR_28000
MPHU: MPHO_11810
MBOK: MBOE_47890
MFG: K6L26_19110(aftC)
MCEE: MCEL_12940
MAB: MAB_2978
MABB: MASS_2913
MCHE: BB28_14985
MSTE: MSTE_02947
MMIN: MMIN_01260(aftC)
MHIB: MHIB_18700(aftC)
ASD: AS9A_1785
MPAK: MIU77_11565(aftC)
CGL: Cgl1897(Cgl1897)
CGB: cg2077
CGU: WA5_1822
CGT: cgR_1726
CGM: cgp_2077
CGJ: AR0_08925
CEF: CE1790
CDI: DIP1690
CDP: CD241_1623(aftC)
CDH: CDB402_1581(aftC)
CDT: CDHC01_1626(aftC)
CDE: CDHC02_1560(aftC)
CDR: CDHC03_1588(aftC)
CDA: CDHC04_1588(aftC)
CDZ: CD31A_1697(aftC)
CDB: CDBH8_1664(aftC)
CDS: CDC7B_1674(aftC)
CDD: CDCE8392_1586(aftC)
CDW: CDPW8_1682(aftC)
CDV: CDVA01_1550(aftC)
CDIP: ERS451417_01703(aftC)
CJK: jk1071
CUR: cu0918
CUA: CU7111_0904(aftC)
CAR: cauri_1439(aftC)
CPSE: CPTA_01768
CPSU: CPTB_01995
CPSF: CPTC_01759
CRD: CRES_1163(aftC)
CUL: CULC22_01304(aftC)
CUC: CULC809_01290(aftC)
CUE: CULC0102_1419(aftC)
CVA: CVAR_1564(aftC)
CTER: A606_06205
CGY: CGLY_08085(aftC)
COA: DR71_2114
CKU: UL82_05965(aftC)
CSP: WM42_2540
CAMG: CAMM_06160
CMIN: NCTC10288_01062(aftC)
CPRE: Csp1_12860(aftC)
CSUR: N24_1964(aftC)
CUO: CUROG_05480(aftC)
NFA: NFA_37340
NNO: NONO_c52550(aftC)
NSR: NS506_05834(aftC)
RER: RER_28550(aftC)
REY: O5Y_13155
ROP: ROP_68480(aftC)
REQ: REQ_20660
RHB: NY08_1194
RRT: 4535765_02099(aftC_1) 4535765_02476(aftC_2)
RCR: NCTC10994_00766(aftC)
GBR: Gbro_2268
GOR: KTR9_2184
GOM: D7316_00788(aftC)
TPR: Tpau_1896
SRT: Srot_1649
SCO: SCO4733(SC6G4.11)
SCT: SCAT_3624
STRM: M444_20855
SLE: sle_29320(sle_29320)
STRD: NI25_15280
SALF: SMD44_05257(aftC)
SALJ: SMD11_4226(aftC)
SFK: KY5_4826
SNF: JYK04_05130(aftC)
TTF: THTE_2349
HSW: Hsw_3686
DKA: DKAM_1443
 » show all
Reference
  Authors
Zhang J, Angala SK, Pramanik PK, Li K, Crick DC, Liav A, Jozwiak A, Swiezewska E, Jackson M, Chatterjee D
  Title
Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors.
  Journal
ACS Chem Biol 6:819-28 (2011)
DOI:10.1021/cb200091m
  Sequence
[mtu:Rv2673]
LinkDB

KEGG   ENZYME: 2.4.2.47
Entry
EC 2.4.2.47                 Enzyme                                 
Name
arabinofuranan 3-O-arabinosyltransferase;
AftC
Class
Transferases;
Glycosyltransferases;
Pentosyltransferases
Sysname
alpha-(1->5)-arabinofuranan:trans,octacis-decaprenylphospho-beta-D-arabinofuranose 3-O-alpha-D-arabinofuranosyltransferase
Reaction(IUBMB)
Adds an alpha-D-arabinofuranosyl group from trans,octacis-decaprenylphospho-beta-D-arabinofuranose at the 3-O-position of an alpha-(1->5)-arabinofuranan chain attached to a beta-(1->5)-galactofuranan chain
Comment
Isolated from Mycobacterium smegmatis. Involved in the formation of the cell wall in mycobacteria.
History
EC 2.4.2.47 created 2012
Pathway
ec00571  Lipoarabinomannan (LAM) biosynthesis
ec00572  Arabinogalactan biosynthesis - Mycobacterium
Orthology
K16647  arabinofuranan 3-O-arabinosyltransferase
Genes
LJRNCTC11533_01968
PPNODA70_07255
PPNMLV28_23420
PRBX636_19420
PSPUNA29_19460
PFGAB870_19545
PCAYFRD00_08085
SIXBSY16_1928
RHNAMJ98_CH03635
REZAMJ99_CH03687
RHTNT26_0804
PDESFE840_015990
BROBRAD285_0712
BGQX265_13975
RPDRPD_2994
TRBHB776_29495
METIDK427_02665
LAPACP90_23165
LABTFIU93_00910
LAGGB0E33_06590
RIDRIdsm_03088
TAWEI545_01070
NGFFRF71_05370
SHYDCJD35_03070
SYAA6768_19695
MTURv2673(aftC)
MTVRVBD_2673
MTCMT2747
MRAMRA_2701
MTFTBFG_12688
MTBTBMG_01300
MTKTBSG_01311
MTZTBXG_001291
MTGMRGA327_16415
MTECCDC5079_2456
MTURCFBS_2825
MTLCCDC5180_2426
MTOMTCTRI2_2725
MTDUDA_2673
MTNERDMAN_2935
MTJJ112_14325
MTUBMT7199_2705(aftC)
MTUCJ113_18595
MTUEJ114_14270
MTXM943_13825
MTUHI917_18775
MTULTBHG_02609
MTUTHKBT1_2816
MTUUHKBT2_2819
MTQHKBS1_2823
MBOBQ2027_MB2692(aftc)
MBBBCG_2686
MBTJTY_2680
MBMBCGMEX_2679
MBKK60_027650
MBXBCGT_2505
MAFMAF_26770
MMICRN08_2957
MCEMCAN_26991
MCQBN44_60124
MCVBN43_40345
MCXBN42_40647
MCZBN45_51052
MLEML1338
MLBMLBr01338
MPAMAP_2793
MAOMAP4_1019
MAVIRC58_05015
MAVURE97_05010
MAVMAV_3565
MITOCO_33990
MIAOCU_34010
MIDMIP_05118
MYOOEM_34370
MCHIAN480_18010
MIROCQ_35210
MMALCKJ54_15880
MLPMLM_1549
MMANMMAN_04000
MSAMycsm_02652
MULMUL_3307
MMCMmcs_2217
MKMMkms_2263
MJLMjls_2206
MMIMMAR_2043
MMAEMMARE11_19670
MMMW7S_17000
MLIMULP_02217
MKNMKAN_25545
MYVG155_13130
MYEAB431_12045
MGOAFA91_25555
MHADB586_14375
MDXBTO20_21180
MSHGMSG_01857
MFJMFLOJ_13930
MSTOMSTO_15440
MSIMMSIM_04740(aftC)
MSAKMSAS_56580
MKUI2456_10045(aftC)
MGROFZ046_17280
MXEMYXE_30890
MNVMNVI_34640(aftC)
MPAGC0J29_11640
MNMMNVM_36290
MGORH0P51_11210
MCOOMCOO_02790
MBAIMB901379_01864(aftC)
MSEOMSEO_06560
MPSEMPSD_20690
MSHOMSHO_51400(aftC)
MHEKJMUB5695_03076
MGAUMGALJ_09550
MLJMLAC_26060(aftC)
MBRDMBRA_44930(aftC)
MSHJMSHI_20300
MKRMKOR_14920
MDFK0O62_12535(aftC)
MMAMK3U93_09070(aftC)
MHOLK3U96_15375(aftC)
MHERK3U94_13720(aftC)
MSENK3U95_10620(aftC)
MPAEK0O64_11715(aftC)
MSPGF6B93_08325
MOTLTS72_14510(aftC)
MLMMLPF_1866(aftC)
MVMMJO54_13870(aftC)
MRFMJO55_11205(aftC)
MPAAMKK62_14995(aftC)
MCROMI149_12580(aftC)
MSMMSMEG_2785
MSGMSMEI_2716
MSBLJ00_13845
MSNLI99_13850
MSHLI98_13855
MVAMvan_2488
MGIMflv_3915
MSPMspyr1_32600
MCBMycch_2184
MNED174_12205
MYNMyAD_11985
MFTXA26_26990
MPHLMPHLCCUG_03077
MVQMYVA_2378
MLLB1R94_17060
MRHMycrhN_5532
MTHN4412656_02700
MHASMHAS_02308(aftC)
MDUMDUV_20840
MCHTMCHIJ_43450
MDRMDOR_15670
MAUUNCTC10437_02326
MMAGMMAD_23810
MMORMMOR_39690
MFXMFAL_04920
MAICMAIC_21020
MIJMINS_22950
MALVMALV_12200
MTYMTOK_42200
MPSCMPSYJ_41940
MARZMARA_15870
MGADMGAD_14410
MHEVMHEL_45970
MSARMSAR_33900
MANYMANY_07510
MAUBMAUB_57060
MPOFMPOR_28000
MPHUMPHO_11810
MMUCC1S78_012355
MMATMMAGJ_58410
MBOKMBOE_47890
MFGK6L26_19110(aftC)
MSEIMSEDJ_36110
MFLVNCTC10271_03050
MCEEMCEL_12940
MABMAB_2978
MMVMYCMA_07515
MABBMASS_2913
MABLMMASJCM_2977
MCHEBB28_14985
MIZBAB75_16035
MSTEMSTE_02947
MSAOMYCSP_13460
MSALDSM43276_02762
MJDJDM601_2419
MTER4434518_02351
MMINMMIN_01260(aftC)
MHIBMHIB_18700(aftC)
ASDAS9A_1785
MPAKMIU77_11565(aftC)
CGLCgl1897(Cgl1897)
CGBcg2077
CGUWA5_1822
CGTcgR_1726
CGSC624_09160
CGGC629_09170
CGMcgp_2077
CGJAR0_08925
CGQCGLAR1_08775
CGXSB89_08615
CEFCE1790
CDIDIP1690
CDPCD241_1623(aftC)
CDHCDB402_1581(aftC)
CDTCDHC01_1626(aftC)
CDECDHC02_1560(aftC)
CDRCDHC03_1588(aftC)
CDACDHC04_1588(aftC)
CDZCD31A_1697(aftC)
CDBCDBH8_1664(aftC)
CDSCDC7B_1674(aftC)
CDDCDCE8392_1586(aftC)
CDWCDPW8_1682(aftC)
CDVCDVA01_1550(aftC)
CDIPERS451417_01703(aftC)
CJKjk1071
CURcu0918
CUACU7111_0904(aftC)
CARcauri_1439(aftC)
CKPckrop_1772 ckrop_1773
CPUCPFRC_06035
CPLCp3995_1219
CPGCP316_06195
CPPCpP54B96_1214
CPKCP1002_07110
CPQCPC231_06040
CPXCPI19_05480
CPZCpPAT10_1189
CORCp267_1247
COPCP31_06425
CODCp106_1173
COSCp4202_1183
COICPCIP5297_06210
COECP258_06210
COUCP162_05095
CPSECPTA_01768
CPSUCPTB_01995
CPSFCPTC_01759
CRDCRES_1163(aftC)
CULCULC22_01304(aftC)
CUCCULC809_01290(aftC)
CUECULC0102_1419(aftC)
CUNCul210932_1370
CUSCulFRC11_1278
CUQCul210931_1262
CUZCul05146_1336
CUJCUL131002_1291
CVACVAR_1564(aftC)
CHNA605_08175
CCNH924_07930
CTERA606_06205
CMDB841_07495
CAZCARG_05515
CFNCFAL_06005
CCGCCASEI_06670
CVTB843_07840
CGYCGLY_08085(aftC)
CIICIMIT_10225
COADR71_2114
CDOCDOO_08300
CHMB842_07505
CSXCSING_06160 CSING_07875(aftC)
CMQB840_07145
CKUUL82_05965(aftC)
CCJUL81_06760
CMVCMUST_08875
CEICEPID_07215
CTEDCTEST_07575
CLWCLAC_05765
CDXCDES_08470
CSPWM42_2540
CSTACSTAT_05965
CCJZccrud_08165
CFCCFLV_07085
CGVCGLAU_07145
CSTRCBE89_06370
CAMGCAMM_06160
CMINNCTC10288_01062(aftC)
CPEGCPELA_04850
CXEFOB82_11620
CEECENDO_05035(aftC) CENDO_06470
CSANE3227_08630
CGKCGERO_06320
CRFFRC0190_01713
CRLNCTC7448_02049
CCHOCCHOA_06640
CPRECsp1_12860(aftC)
CPSOCPPEL_05055
CSURN24_1964(aftC)
CCYSSAMEA4530656_0952
CMATHBA49_01080
CYZC3B44_04900
CKFI6I12_05975
CANSGP473_04940
CLIAC3E79_06330
CPRPI6I69_00590
CAMCI6I65_01985
CGLUI6J20_02900
CUOCUROG_05480(aftC)
CLIZG7Y31_04980 G7Y31_06930
CSILCBE74_07035
CTUBI6I74_00235
CLUJIAU68_06635
CQNG7Y29_06170
CKWCKALI_06550
CCOECETAM_07560
COKCOCCU_08215
CZOIAU67_00515 IAU67_04905
CORYFQV43_05795
CMFGWO64_005330
CWKIA203_07250
CUWLH390_06510
CPOYGP475_06630
BFVC628_09120
NFANFA_37340
NFRERS450000_00166
NCYNOCYR_3626
NBRO3I_029265
NNONONO_c52550(aftC)
NSLBOX37_20275
NSRNS506_05834(aftC)
NTPCRH09_20950 CRH09_24375
NOZDMB37_08180
NODFOH10_18540
NAHF5544_29295
NADNCTC11293_05099 NCTC11293_05533
NWLNWFMUON74_25490
NIEKV110_28420
NTCKHQ06_30345
NHUH0264_29295
NYALTV02_04700
NGPLTT66_24850
RHARHA1_ro06863
RERRER_28550(aftC)
REYO5Y_13155
REBXU06_13375
RQIC1M55_14385
ROPROP_68480(aftC)
ROAPd630_LPD03488
REQREQ_20660
RPYY013_01980
RBYCEJ39_12675 CEJ39_14150
RHBNY08_1194
RAVAAT18_12370
RFAA3L23_04438
RHSA3Q41_03829
RHWBFN03_06630
RRZCS378_02135
RHUA3Q40_01546
RHQIM25_15965 IM25_17395 IM25_23715
RHODAOT96_24595
RRT4535765_02099(aftC_1) 4535765_02476(aftC_2)
RCRNCTC10994_00766(aftC)
RTMG4H71_20515
RKOJWS14_36985
RGOKYT97_02025
ROZCBI38_17000
GBRGbro_2268
GPOGPOL_c21630
GORKTR9_2184
GOQACH46_09420
GTABCM27_11685
GOCCXX93_13435
GITC6V83_09855
GRUGCWB2_13990
GOMD7316_00788(aftC)
GAVC5O27_14100
GODGKZ92_12860
GAMGII34_10555
GJIH1R19_10885
GOILK459_22555
GHNMVF96_11075
GAMIIHQ52_16600
SPINKV203_07860
TPRTpau_1896
TSMASU32_10175
TPULTPB0596_26970
SRTSrot_1649
DTMBJL86_1775
DITC3V38_14530
DIZCT688_08685
DPCA6048_08920
DLUA6035_08475
CBQAL705_00630
TOYFO059_09935
SCOSCO4733(SC6G4.11)
SCTSCAT_3624
SCYSCATT_36180
SLVSLIV_14695
SGUSGLAU_20290
STRMM444_20855
SAMBSAM23877_4528
STRFASR50_21590
SLEsle_29320(sle_29320)
SPAVSpa2297_19950
STRTA8713_23715
SALWCP975_21155
SLSSLINC_5072
STRDNI25_15280
SSIAA7J05_14875
SALFSMD44_05257(aftC)
SALJSMD11_4226(aftC)
SLXSLAV_15780
SFKKY5_4826
SNZDC008_20990
SDXC4B68_16055
SGDELQ87_15790
SCYAEJ357_27875
SASTCD934_18725
SKACP970_17190
SGZC0216_03075
SVNCP980_13710
SRKFGW37_12435
SGALCP966_22050
SRIMCP984_22405
SSUBCP968_13810
SFUGCNQ36_21260
SPACB1H29_14880
SCHACP983_17235
SNFJYK04_05130(aftC)
SVDCP969_23280
SMOBJ7W19_12145
SXNIAG42_14120
SHKJ2N69_22180
SLFJEQ17_28065
PBROHOP40_14685
KPHYAOZ06_45450
DVCDvina_37810
TTFTHTE_2349
GESVT84_20350
GOGC1280_23685
TRSTerro_1507
HSWHsw_3686
FTEFluta_3481
DKADKAM_1443
DFDDesfe_0066
 » show all
Reference
1  [PMID:18627460]
  Authors
Birch HL, Alderwick LJ, Bhatt A, Rittmann D, Krumbach K, Singh A, Bai Y, Lowary TL, Eggeling L, Besra GS
  Title
Biosynthesis of mycobacterial arabinogalactan: identification of a novel alpha(1-->3) arabinofuranosyltransferase.
  Journal
Mol Microbiol 69:1191-206 (2008)
DOI:10.1111/j.1365-2958.2008.06354.x
  Sequence
[cgl:Cgl1897] [msm:MSMEG_2785] [mtu:Rv2673]
Reference
2  [PMID:21595486]
  Authors
Zhang J, Angala SK, Pramanik PK, Li K, Crick DC, Liav A, Jozwiak A, Swiezewska E, Jackson M, Chatterjee D
  Title
Reconstitution of functional mycobacterial arabinosyltransferase AftC proteoliposome and assessment of decaprenylphosphorylarabinose analogues as arabinofuranosyl donors.
  Journal
ACS Chem Biol 6:819-28 (2011)
DOI:10.1021/cb200091m
  Sequence
[mtu:Rv2673]
Other DBs
ExplorEnz - The Enzyme Database: 2.4.2.47
IUBMB Enzyme Nomenclature: 2.4.2.47
ExPASy - ENZYME nomenclature database: 2.4.2.47
BRENDA, the Enzyme Database: 2.4.2.47
LinkDB

DBGET integrated database retrieval system