KEGG ORTHOLOGY: K16676

ORTHOLOGY: K16676

Entry

K16676                      KO

Symbol

LPP

Name

lipoma-prefererred partner

Pathway

map04391

Hippo signaling pathway - fly

Disease

H00003

Acute myeloid leukemia

Brite

KEGG Orthology (KO) [BR:ko00001]
09130 Environmental Information Processing
  09132 Signal transduction
   04391 Hippo signaling pathway - fly
    K16676  LPP; lipoma-prefererred partner

Genes

HSA:

4026(LPP)

PTR:	471037(LPP)

PPS:	100985945(LPP)

GGO:	101150312(LPP)

PON:	100442010(LPP)

PPYG:

129032374(LPP)

NLE:	100604267(LPP)

HMH:	116479958(LPP)

SSYN:

134732985(LPP)

MCC:	709317(LPP)

MCF:	102143840(LPP)

MTHB:

126948041

MNI:	105470874(LPP)

CSAB:

103241887(LPP)

CATY:

105575203(LPP)

PANU:

101022173(LPP)

TGE:	112617932(LPP)

MLEU:

105553747(LPP)

RRO:	104653591(LPP)

RBB:	108530472(LPP)

TFN:	117084365(LPP)

PTEH:

111544278(LPP)

CANG:

105525828(LPP)

CJC:	100414935(LPP)

SBQ:	101035767(LPP)

CIMI:

108318535

ANAN:

105729906(LPP)

CSYR:

103260835(LPP)

MMUR:

105860435(LPP)

LCAT:

123630380

ERUF:

138386409(LPP)

PCOQ:

105808590(LPP)

OGA:	100955244(LPP)

MMU:	210126(Lpp)

MCAL:

110311655(Lpp)

MPAH:

110329648(Lpp)

RNO:	288010(Lpp)

MCOC:

116085760(Lpp)

ANU:	117717864(Lpp)

ASYL:

127666323(Lpp)

MUN:	110547516(Lpp)

CGE:	100753874(Lpp)

MAUA:

101828273

PROB:

127227017(Lpp)

PLEU:

114697100

PMAV:

102921351(Lpp)

MORG:

121464860

MFOT:

126512300

AAMP:

119824574

CNL:	130870775(Lpp)

NGI:	103739332(Lpp)

HGL:	101712406(Lpp)

CPOC:

100731600(Lpp)

CCAN:

109699524(Lpp)

DORD:

105988001(Lpp)

DSP:

122097571

DMER:

138832221(Lpp)

PLOP:

125351882

NCAR:

124992440

SVUL:

306670546(LPP)

MMMA:

107154372

ITI:

101967781

SCIL:

308654023(LPP)

MAVE:

308263719(LPP)

OCU:

100354370

OPI:

101533145

OCZ:	121167276 121171399

TUP:	102491353(LPP)

GVR:	103596441(LPP)

CFA:

478670

CLUD:

112645817

VVP:	112926307(LPP)

VLG:

121477519

NPO:	129498881(LPP)

AML:	100479802(LPP)

UMR:

103676028

UAH:	113253627(LPP)

UAR:

123801309

ELK:

111150501

LLV:

125102019

MPUF:

101676863(LPP)

MNP:	132011939(LPP)

MLK:	131824732(LPP)

NVS:

122908796

MMAQ:

308349813(LPP)

ORO:	101375520(LPP)

EJU:	114207174(LPP)

ZCA:	113918675 113920491

MLX:	118006934(LPP)

MANO:

123863524(LPP)

NSU:

LWW:

FCA:

PYU:

PCOO:

112850184(LPP)

PBG:

122491615

PVIV:

125174865(LPP)

LRUF:

124526689

LGF:

123611099

AJU:

106968013

PTG:	102953305(LPP)

PPAD:

109275297(LPP)

PUC:

125921821

PLEZ:

122229688

HHV:

120233110

CCRU:

144223598(LPP)

BTA:	524132(LPP)

BOM:	102283878(LPP)

BIU:	109556824(LPP)

BJV:	133245220(LPP)

BBUB:

102391153

BKE:	129643725(LPP)

BBIS:

104998644(LPP)

CHX:	102168579(LPP)

OAS:	101110107(LPP)

OCAN:

138422676(LPP)

BTAX:

128049422(LPP)

CSUM:

138078278(LPP)

ODA:

120872594

CCAD:

122444800

MREE:

136173455(LPP)

OVR:	110133881(LPP)

MBEZ:

129544522(LPP)

SSC:	100626969(LPP)

CFR:	102514828(LPP)

CBAI:

105072346(LPP)

CDK:	105085831(LPP)

VPC:	102525908(LPP)

BACU:

103007539(LPP)

BMUS:

118894686

LVE:	103088599(LPP)

OOR:	101287329(LPP)

LALB:

132521075(LPP)

GMF:	115855531(LPP)

DDP:	132424833(LPP)

SCOO:

307186530(LPP)

PCRS:

137225024(LPP)

DLE:	111172754(LPP)

PCAD:

102976834(LPP)

PSIU:

116752850(LPP)

PPHC:

136122660(LPP)

NASI:

112414749(LPP)

HAMP:

307052988(LPP)

ECB:	100059679(LPP)

EPZ:	103551324(LPP)

EAI:

106832552

MYB:	102240350(LPP)

MYD:	102757619(LPP)

MMYO:

118675946

MLF:	102424777(LPP)

MDT:	132230226(LPP)

MYUM:

139004001(LPP)

PKL:

118723992

EFUS:

103295158(LPP)

POTS:

308241766(LPP)

MNA:	107527302(LPP)

DRO:	112308423(LPP)

SHON:

118981161

AJM:	119039090(LPP)

PDIC:

114490441

PHAS:

123826937

MMF:

118617124

PPAM:

129079873(LPP)

HAI:	109371205(LPP)

RFQ:	117032041(LPP)

RHII:

308509640(LPP)

PALE:

102891584(LPP)

PGIG:

120592950

PVP:	105306572(LPP)

RAY:

107505903

MJV:	108392320(LPP)

TOD:	119258086(LPP)

SARA:

101539565(LPP)

SFUM:

130030593(LPP)

SETR:

126012137(LPP)

LAV:	100657158(LPP)

TMU:

101350076

DNM:	101422775(LPP)

MDO:	100018322(LPP)

GAS:

123242014

SHR:	100928195(LPP)

AFZ:

127558331

PCW:	110210188(LPP)

TVP:

118846457

PBRV:

138157660(LPP)

MLAO:

141490591(LPP)

OAA:

100080375

TACU:

119930838

GGA:	429148(LPP)

PCOC:

116235345(LPP)

MGP:

100549525

CJO:	107318154(LPP)

TPAI:

128082637(LPP)

LMUT:

125697421

NMEL:

110398652(LPP)

APLA:

101797556

AACU:

137861303(LPP)

OJA:	118171239(LPP)

BCLA:

308447406(LPP)

ACYG:

106044793(LPP)

ABRC:

308199590(LPP)

CATA:

118246993(LPP)

AFUL:

116492784(LPP)

TGU:	100225046(LPP)

LSR:	110473900(LPP)

VMC:	128811938(LPP)

VCHA:

128792691(LPP)

AIB:	137479922(LPP)

SCAN:

103815380(LPP)

PMOA:

120504263

OTC:

121336716

PRUF:

121353799

ATRC:

139594991(LPP)

MATE:

118689903(LPP)

MAEN:

136560599(LPP)

GFR:	102034991(LPP)

FAB:	101821934(LPP)

OMA:	130256656(LPP)

PHI:	102099822(LPP)

PMAJ:

107208832(LPP)

CCAE:

111933444(LPP)

CCW:

104687932

CBRC:

103625210(LPP)

ACOE:

138114589(LPP)

ETL:	114057610(LPP)

ZAB:	102073527(LPP)

ZLE:	135451796(LPP)

SVG:	106850394(LPP)

MMEA:

130579656(LPP)

HRT:	120757424(LPP)

SATI:

136365465(LPP)

CFAI:

136295086(LPP)

CCIC:

134047896(LPP)

NNT:

104410266

SHAB:

115611781(LPP)

POCC:

134157405(LPP)

FPG:	101914226(LPP)

FCH:	102059418(LPP)

FRS:

119156532

ACUN:

113483447(LPP)

ANOC:

141963325(LPP)

SURA:

141946932(LPP)

TALA:

104364384

ACHC:

115347044

HLE:	104835181(LPP)

AGEN:

126039599

HHAR:

128149038(LPP)

BBUT:

142032688(LPP)

GCL:

CSTI:

LDI:

DPUB:

PPUS:

135187141(LPP)

IIN:	128970702(LPP)

EGZ:

104123373

NNI:	104015664(LPP)

PCRI:

104026209

PARX:

142059831(LPP)

PADL:

103925397(LPP)

AFOR:

103901528(LPP)

CBOR:

142085340(LPP)

CBOY:

140654880(LPP)

MAME:

142412253(LPP)

CLV:	102092200(LPP)

CNIC:

135991268(LPP)

NMAY:

308043363(LPP)

PLET:

104624024

EHS:

104509727

CUCA:

104063445(LPP)

PCUR:

138724466(LPP)

GAME:

129209783(LPP)

OHA:	104326846(LPP)

ACAR:

104526801

CEUR:

306721929(LPP)

CPEA:

104390654(LPP)

CVF:	104284968(LPP)

RTD:	128911413(LPP)

CRID:

134516905(LPP)

LMIC:

141745390(LPP)

NARQ:

141468191(LPP)

AAM:	106497986(LPP)

AROW:

112968494(LPP)

NPD:	112952489(LPP)

DNE:	112979356(LPP)

SCAM:

104148854(LPP)

ASN:	102377885(LPP)

AMJ:	102569670(LPP)

CPOO:

109308544(LPP)

GGN:	109288098(LPP)

PSS:	102450085(LPP)

CIZ:	142018729(LPP)

CMY:

102934171

CCAY:

125642270

LKP:	140917052(LPP)

NDS:	141993750(LPP)

DCC:

119861738

CPIC:

101931062(LPP)

TST:	117882820(LPP)

EOB:	135883303(LPP)

CABI:

116823023(LPP)

MRV:

120371563

EMQ:	137161675(LPP)

ACS:	100554903(lpp)

ASAO:

132770372(LPP)

PVT:	110090110(LPP)

SUND:

121924985

PBI:	103067074(LPP)

CTIG:

120296640

TSR:

106548139

PGUT:

117669813(LPP)

APRI:

131200431(LPP)

VKO:

123036804

PMUA:

114598130(LPP)

PRAF:

128413334(LPP)

ZVI:	118093531(LPP)

HCG:	128352452(LPP)

GJA:

107113843

EMC:	129332400(LPP)

XLA:	108718052 735087(lpp.L)

XTR:	779875(lpp)

NPR:	108804589(LPP)

RTEM:

120936862

ACAT:

141139869(LPP)

PADS:

140328553(LPP)

BBUF:

120997987

BGAR:

122936356

DTC:	141100732(LPP)

HSQ:	130361857(LPP)

PCOB:

134909522(LPP)

PWL:	138265231(LPP)

MUO:	115478964(LPP)

GSH:	117366593(LPP)

DRE:	573024(lpp)

DAES:

130230747(lpp)

SRX:	107717931 107752632

SANH:

107684332 107696776

SGH:	107552245 107590653

CCAR:

CAUA:

CGIB:

PTET:

LROH:

127166757(lpp)

GRF:	141346513(lpp)

OMC:	131541856(lpp)

PPRM:

120493070

RKG:	130081305(lpp)

SCEP:

307165322(lpp)

MAMB:

125273912

CIDE:

127514060

CERY:

137011572(lpp)

MASI:

127446356 127449647

MANU:

129450583(lpp)

PDAB:

135718513(lpp)

IPU:	108271779(lpp)

IFU:	128614937(lpp)

PHYP:

113530488

SMEO:

124382710

TFD:

113642945

TVC:	132844364(lpp)

CGAR:

128526404(lpp)

NGRA:

132885296(lpp)

TRN:	134316781(lpp)

AMEX:

103032787(lpp)

CMAO:

118808028

EEE:

113575901

CHAR:

105895221

SPIL:

134101900(lpp)

ASAD:

121724846

TRU:	101079924(lpp)

TFS:	130528482(lpp)

TNG:	GSTEN00025753G001 GSTEN00025755G001

NCC:

104953766

TBEN:

117478126(limd1b) 117491043(lpp)

CGOB:

115006825 115016043

PGEO:

117445047(lpp) 117455539(limd1b)

GACU:

117542529(limd1b) 117559079(lpp)

EMAC:

134869416(lpp) 134875461

ELY:	117253940(lpp) 117264100(limd1b)

EFO:	125895302 125904375(limd1b)

PLEP:

121940998 121958152(limd1b)

SLUC:

116047507(limd1b) 116058749

SVIT:

144523906(lpp)

ECRA:

117950853(lpp) 117957184(limd1b)

ESP:	116696051 116701755

PFLV:

114561339 114568662

PFLT:

120565727

GAT:	120823511 120826066(limd1b)

PPUG:

119216475(lpp) 119218885(limd1b)

AFB:	129094437(lpp) 129097658(limd1b)

CLUM:

117729200(lpp) 117739147(limd1b)

PSWI:

130193897(lpp) 130195838(limd1b)

CANA:

137784355(limd1b) 137794606(lpp)

TBU:	306738791(lpp)

CVE:	137870499(lpp) 137872966(limd1b)

AMIR:

142935048(lpp)

MSAM:

119901159 119907818(limd1b)

SCHU:

122864250 122877612

EARM:

139287888(lpp) 139299263

CUD:

121512653

SPUL:

138607928(lpp) 138608691(limd1b)

LMIX:

132957235(lpp) 132973507

HTC:	141789109(lpp) 141803532(limd1b)

ALAT:

119016534 119028226

ASTR:

137598410(lpp)

PKLU:

139202797(lpp) 139215038(limd1b)

LCO:	104925827 109139761

AMMM:

307254533(lpp)

MZE:	101474685(lpp) 101476707(limd1b)

ONL:	100694679 102078931

OAU:	116312983 120435629(limd1b)

OLA:	101159832 101167359

OML:	112150649(lpp) 112162501(limd1b)

CSAI:

133458070(lpp) 133461007(limd1b)

XMA:	102221655 102237924

XCO:	114150913 114156205

XHE:	116725733 116731494

PRET:

103463937(lpp)

PFOR:

103154538

PLAI:

106949590 106958206

PMEI:

106908361 106928133

GAF:	122838285 122843416(limd1b)

PPRL:

129354171(limd1b) 129372727(lpp)

CVG:

107088672

CTUL:

119795838

GMU:	124874026 124879682(limd1b)

NFU:

107387414

KMR:	108239645(limd1b) 108240214(lpp)

ALIM:

106520843 106530391

NWH:

119430816

LTU:	140275158(limd1b) 140312340(lpp)

MCEP:

125008969 125020249(limd1b)

AOCE:

111567136(lpp)

EJA:	138199001(lpp) 138214899(limd1b)

BFRE:

138621707(limd1b) 138624122(lpp)

LCF:	108878886(lpp) 108890305

CSEM:

103399942

POV:	109625468 109639154

SSEN:

122780680 122786845

SSOE:

131447938(limd1b) 131465406(lpp)

HHIP:

117760181(lpp) 117770124(limd1b)

HSP:	118120925 118124867(limd1b)

PPLT:

128447631(lpp) 128462191(limd1b)

SMAU:

118291975 118317902

SDU:

111231933

SLAL:

111651747 111669589

XGL:	120786437(limd1b) 120790469

HCQ:

109532339

SSCV:

125970566(lpp) 125986756(limd1b)

SBIA:

133503181(lpp)

PEE:	133406101(lpp)

PTAO:

133470936(limd1b) 133481148(lpp)

BPEC:

110154722

ENY:	140354473(lpp) 140361463

MALB:

109965713

BSPL:

114853385(lpp) 114865896(limd1b)

SJO:	128361858(lpp)

SSCO:

133984720(lpp)

TTY:	137188241(lpp)

GMH:	115535909 115555384

STRU:

115151448(lpp) 115158899

OTW:	112241960 112242029

OMY:	110510444 110518923 118936379 118964739

OGO:

123996316

OKI:

109883962

OKE:

118381706

OMM:	135511527 135524811(lpp)

OCLA:

139415803

SALP:

112074238 112076569

SNH:	120053584 120054371

SFON:

129842243

CCLU:

121534174 121577417

ELS:

105011323

OEP:	134011298(lpp)

SFM:

108921430

PKI:

111836633

AANG:

118226307(lpp) 118229691

AROT:

135252551(lpp) 135256511

CCOG:

133127757(lpp) 133128600

LOC:	102699045(lpp)

PSPA:

121322829 121326657

ARUT:

117417294 117423634

PSEX:

120537137

LCM:	102351144(LPP)

RTP:

109915894

CPLA:

122556090

CPUN:

140478803(lpp)

HOC:	132821823(lpp)

SCAU:

119976480(lpp)

LERI:

129703440(lpp)

HAKA:

140725808

PMRN:

116938067 116946914

LRJ:	133352356 133352420

BFO:

BBEL:

CIN:

CLEP:

SPU:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

SKO:

PFLL:

DME:	Dmel_CG32018(Zyx)

DER:

6555826

DSE:

6620108

DSI:	Dsimw501_GD24360(Dsim_GD24360)

DYA:	Dyak_GE14489

DSR:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI14099

DAZ:

DNV:

DHE:

CCAT:

RZE:

AOQ:

ALUD:

TDA:	119677732 119678243

MDE:	101887657 131806873

SCAC:

106094989

CVJ:	135954718(Zyx)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

ANIL:

AALI:

ADAR:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ002448

CPII:

CBRI:

CNS:

BCOO:

LLL:

PPAP:

CFEL:

BMOR:

BMAN:

MSEX:

DPL:	KGM_203417 KGM_207523

BANY:

112057986 112058068

MJU:	123870174 123875596

NIQ:	126772364 126775099

VCD:	124537381(LOC124537381) 124543827(LOC124543827)

MCIX:

123658498 123661597

PMAC:

106711194 106717681

PPOT:

106102379 106105690

PXU:	106114226 106121933

BPHI:

137933788

PRAP:

110991674 110993335

PBX:	123712743 123713608

PNAP:

125058697 125062342

ZCE:	119832000 119833982

CCRC:

123696598 123698857

LSIN:

126971942 126974456

AAGE:

121733517 121737161

HAW:	110370633 110376098

HZE:	124633942 124637949

TNL:	113504183 113505824

SLIU:

111353808 111357592

OFU:	114350250 114362743

ONU:	135076302 135079973

ATRA:

106132692 106141853

GMW:

113521618

ECLR:

140745029 140752512

PXY:	105380202(LOC105380202) 105391320(LOC105391320)

PGW:	126371278 126374680

LGLY:

CSTB:

CFUM:

TCA:

TMOL:

138129896(Zyx)

DPA:

109540074

ESIM:

136415823(Zyx)

EFOR:

136345107

SOY:	115875994 115875996

RFG:	143194356 143194357 143194359

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

APLN:

PPYR:

OTU:

CCRN:

AME:

ACER:

ALAB:

ADR:

AFLR:

BIM:

BBIF:

BVK:

BVAN:

BHUN:

BTER:

BAFF:

BFER:

139992963(Zyx)

BPYO:

BPAS:

FVI:

CCAL:

OBB:

OLG:

MGEN:

APUR:

144468500(Zyx)

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108724667(Zyx)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139112175(Zyx)

TLN:	139823137(Zyx)

TAME:

143901057(Zyx)

TNY:	139767716(Zyx)

HST:

DQU:

CFO:

FEX:

PMEC:

138941168(Zyx)

LHU:	105677066(Zyx)

PGC:

109862488

OBO:	105274952(Zyx)

PCF:

PFUC:

VPS:

VCRB:

VVE:

NVI:

CSOL:

TPRE:

LHT:

LBD:

MDL:	103569234 103576935

CGLO:

123269156

CTYP:

141526740(Zyx)

FAS:	105265594 105272986

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124218056(Zyx)

NFB:

NLO:

NVG:

AROA:

API:	100168023 100573515

DNX:

AGS:

RMD:

ACOO:

DVT:

DCI:

CLEC:

HHAL:

106679786(Zyx)

NLU:

111055194

LDA:	142327247(Zyx)

HVI:

124362159

MQU:

128990748

PHU:	Phum_PHUM337030

FOC:

TPAL:

ZNE:

CSEC:

PAME:

138714801(Zyx)

SGRE:

126298375

BROR:

134529117

IEL:	124157687(Zyx)

HAMR:

139686305(Zyx)

FCD:

110856995

DPX:	DAPPUDRAFT_215208

DMK:

116930627

DPZ:

124349636

AFRA:

136030158

EAF:	111698800 111712910 111713225 111714613

LSM:

TCF:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

123767578(Zyx)

PTRU:

SPRM:

ESN:

MNZ:

MRJ:	136853082(Zyx)

PORN:

OOT:

HAZT:

PPOI:

ISC:

DSV:

DALB:

135915495(Zyx)

RSAN:

119389853

RMP:	119176229(Zyx)

VDE:	111254232 111254264

VJA:

111263396

GOE:

100903772

TUT:	107370146 107371426

DPTE:

CSCU:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_F42G4.3(zyx-1)

CBR:	CBG_02797(Cbr-zyx-1)

NAI:	NECAME_04177

LOA:	LOAG_18788

TSP:

Tsp_05663

HRO:	HELRODRAFT_106874

LGI:	LOTGIDRAFT_135992

PVUL:

PCAN:

LSAX:

BARL:

GAE:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

PMAX:

AIRR:

YBA:

MMER:

RPHI:

MAEA:

OSN:

LJP:

LAK:

LLON:

NVE:	5503620 5511225

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:	101236590(LOC101236590)

HSY:

RES:

AQU:

CCLM:

DFA:

Reference

PMID:19701494

Authors

Grunewald TG, Pasedag SM, Butt E

Title

Cell Adhesion and Transcriptional Activity - Defining the Role of the Novel Protooncogene LPP.

Journal

Transl Oncol 2:107-16 (2009)
DOI:10.1593/tlo.09112

Reference

PMID:21666802

Authors

Rauskolb C, Pan G, Reddy BV, Oh H, Irvine KD

Title

Zyxin links fat signaling to the hippo pathway.

Journal

PLoS Biol 9:e1000624 (2011)
DOI:10.1371/journal.pbio.1000624

Reference

PMID:8812423

Authors

Petit MM, Mols R, Schoenmakers EF, Mandahl N, Van de Ven WJ

Title

LPP, the preferred fusion partner gene of HMGIC in lipomas, is a novel member of the LIM protein gene family.

Journal

Genomics 36:118-29 (1996)
DOI:10.1006/geno.1996.0432

Sequence

[hsa:4026]

LinkDB

DBGET integrated database retrieval system