KEGG ORTHOLOGY: K16745

ORTHOLOGY: K16745

Entry

K16745                      KO

Symbol

B9D2

Name

B9 domain-containing protein 2

Disease

H00261

Meckel syndrome

H00530

Joubert syndrome and related disorders

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   03037 Cilium and associated proteins
    K16745  B9D2; B9 domain-containing protein 2
Cilium and associated proteins [BR:ko03037]
Primary cilia and associated proteins
  MKS complex
   K16745  B9D2; B9 domain-containing protein 2

Other DBs

GO:

0036038

Genes

HSA:	80776(B9D2)

PTR:	739216(B9D2)

PPS:	100981952(B9D2)

GGO:	101153499(B9D2)

PON:	100460347(B9D2)

PPYG:

129019735(B9D2)

NLE:	100583510(B9D2)

HMH:	116480650(B9D2)

SSYN:

129466435(B9D2)

MCC:	704873(B9D2)

MCF:	102130188(B9D2)

MTHB:

126941793

MNI:	105495299(B9D2)

CSAB:

103234730(B9D2)

CATY:

105598018(B9D2)

PANU:

101008016(B9D2)

TGE:	112612163(B9D2)

MLEU:

105542008(B9D2)

RRO:	104676085(B9D2)

RBB:	108536162(B9D2)

TFN:	117075977(B9D2)

PTEH:

111554143(B9D2)

CANG:

105505776 105507835(B9D2)

CJC:	100402332(B9D2)

SBQ:	101048314(B9D2)

CIMI:

108285662(B9D2)

ANAN:

105723448(B9D2)

CSYR:

103261183(B9D2)

MMUR:

105869120(B9D2)

LCAT:

123624076(B9D2)

ERUF:

138375105(B9D2)

PCOQ:

105820565(B9D2)

OGA:	100949313(B9D2)

MMU:	232987(B9d2)

MCAL:

110298747(B9d2)

MPAH:

110336799(B9d2)

RNO:	308443(B9d2)

MCOC:

116101856(B9d2)

ANU:	117713594(B9d2)

ASYL:

127673138(B9d2)

CGE:	103160326(B9d2)

MAUA:

101829855(B9d2)

PROB:

127238701(B9d2)

PLEU:

114685306(B9d2)

PMAV:

102903034(B9d2)

MORG:

121449621(B9d2)

MFOT:

126494579

AAMP:

119821130(B9d2)

CNL:	130869850(B9d2)

NGI:	103751515(B9d2)

HGL:	101704578(B9d2)

CPOC:

100730785(B9d2)

CCAN:

109685634(B9d2)

DORD:

106000884(B9d2)

DSP:	122097413(B9d2)

DMER:

138811353 138811689

PLOP:

125339020(B9d2)

NCAR:

124967408

MMMA:

107151428(B9d2)

ITI:	101970281(B9d2)

OCU:

100357786

OPI:	101533140(B9D2)

OCZ:	121153623(B9D2)

TUP:	102481810(B9D2)

GVR:	103599184(B9D2)

CFA:	476451(B9D2)

CLUD:

112645427(B9D2)

VVP:	112928348(B9D2)

VLG:	121478764(B9D2)

NPO:	129500304(B9D2)

AML:	100484623(B9D2)

UMR:	103677393(B9D2)

UAH:	113243539(B9D2)

UAR:	123781976(B9D2)

ELK:

111161578

LLV:

125089689

MPUF:

101694391(B9D2)

MNP:	132005080(B9D2)

MLK:	131817497(B9D2)

NVS:	122912065(B9D2)

ORO:	101364862(B9D2)

EJU:	114202557(B9D2)

ZCA:	113936128(B9D2)

MLX:	118022633(B9D2)

MANO:

123855689(B9D2)

NSU:	110590074(B9D2)

LWW:	102746330(B9D2)

FCA:	101087954(B9D2)

PYU:	121018483(B9D2)

PCOO:

112850698(B9D2)

PBG:	122494006(B9D2)

PVIV:

125152870(B9D2)

LRUF:

124511096

LGF:	123578898(B9D2)

AJU:

106987710

PTG:	102959033(B9D2)

PPAD:

109257976(B9D2)

PUC:

125915434

PLEZ:

122207609(B9D2)

HHV:	120242237(B9D2)

CCRU:

144239717(B9D2)

BTA:	616609(B9D2)

BOM:	102283648(B9D2)

BIU:	109572973(B9D2)

BBUB:

102413110(B9D2)

BKE:	129630925(B9D2)

BBIS:

104995382(B9D2)

CHX:	102170722(B9D2)

OAS:	101102082(B9D2)

BTAX:

128063624(B9D2)

CSUM:

138096698(B9D2)

ODA:	120872452(B9D2)

CCAD:

122421578(B9D2)

MREE:

136161364(B9D2)

OVR:	110141456(B9D2)

MBEZ:

129546783(B9D2)

SSC:	100511384(B9D2)

CFR:	102505470(B9D2)

CBAI:

105062880(B9D2)

CDK:	105093369(B9D2)

VPC:	102538890(B9D2)

BACU:

103003343(B9D2)

BMUS:

118885432(B9D2)

LVE:	103075290(B9D2)

OOR:	101285943(B9D2)

LALB:

132509492(B9D2)

GMF:	115862404(B9D2)

DDP:	132416475(B9D2)

DLE:	111180825(B9D2)

PCAD:

102975156(B9D2)

PSIU:

116743551(B9D2)

PPHC:

136141162(B9D2)

NASI:

112415267(B9D2)

ECB:	100146820(B9D2)

EPZ:	103562532(B9D2)

EAI:	106843816(B9D2)

MYB:	102241141(B9D2)

MYD:	102774423(B9D2)

MMYO:

118674594(B9D2)

MLF:	102428425(B9D2)

MDT:	132216837(B9D2)

MYUM:

138996662(B9D2)

PKL:	118702322(B9D2)

EFUS:

103284287(B9D2)

MNA:	107534177(B9D2)

DRO:	112320179(B9D2)

SHON:

118982089(B9D2)

AJM:	119058461(B9D2)

PDIC:

114511069(B9D2)

PHAS:

123823804(B9D2)

MMF:	118638487(B9D2)

PPAM:

129076674(B9D2)

HAI:	109376594(B9D2)

RFQ:	117035097(B9D2)

PALE:

102881897(B9D2)

PGIG:

120586592(B9D2)

PVP:	105307946(B9D2)

RAY:	107505491(B9D2)

MJV:	108383729(B9D2)

TOD:	119249310 119249354(B9D2)

SARA:

101551079(B9D2)

SFUM:

130044174(B9D2)

SETR:

126028170(B9D2)

LAV:	100667921(B9D2)

TMU:

101342795

ETF:	101650155(B9D2)

DNM:	101432133(B9D2)

MDO:	100015870(B9D2)

GAS:	123242987(B9D2)

SHR:	105749944(B9D2)

AFZ:

127556233

PCW:	110202368(B9D2)

TVP:	118838849(B9D2)

PBRV:

138153914(B9D2)

MLAO:

141509532(B9D2)

OAA:	114812000(B9D2)

TACU:

119946033(B9D2)

GGA:	112530472(B9D2)

PCOC:

116241823(B9D2)

CJO:	107307102(B9D2)

AACU:

137847361(B9D2)

AFUL:

116501530(B9D2)

LSR:	110482798(B9D2)

PMOA:

120513673(B9D2)

PRUF:

121356991

ATRC:

139586542(B9D2)

OMA:	130266188(B9D2)

PHI:	102112591(B9D2)

PMAJ:

107198991(B9D2)

ACOE:

138101278 138101280

ZLE:	135441733(B9D2)

SHAB:

115603260(B9D2)

HLE:	104831504(B9D2)

AGEN:

126036627

HHAR:

128138114(B9D2)

BBUT:

142026821(B9D2)

GCL:

127028061

CBOR:

142074023(B9D2)

CBOY:

140645465(B9D2)

MAME:

142403737(B9D2)

CNIC:

136001027(B9D2)

LMIC:

141734979(B9D2)

AMJ:	106739523(B9D2)

CIZ:	142024485(B9D2)

CMY:	119564363(B9D2)

CCAY:

125628072(B9D2)

LKP:	140902126(B9D2)

NDS:	141976513(B9D2)

DCC:	119847273(B9D2)

CPIC:

101945623(B9D2)

CABI:

116833891(B9D2)

ACS:	100558744(b9d2)

ASAO:

132780796(B9D2)

PVT:	110088532(B9D2)

SUND:

121917545 121917597

PBI:	103067511(B9D2)

PMUR:

107295273(B9D2)

CTIG:

120319892(B9D2)

TSR:

106551443

PGUT:

117677593(B9D2)

PCAE:

139321159(B9D2)

APRI:

131204363(B9D2)

PTEX:

113455058(B9D2)

NSS:	113426024(B9D2)

VKO:	123026100(B9D2)

PMUA:

114603304(B9D2)

PRAF:

128418276(B9D2)

ZVI:	118086684(B9D2)

HCG:	128332611(B9D2)

GJA:	107123915(B9D2)

STOW:

125434211(B9D2)

EMC:	129343436(B9D2)

XLA:	444413(b9d2.L)

XTR:	100380173(b9d2)

NPR:	108786676(B9D2)

RTEM:

120913379(B9D2)

ACAT:

141107743(B9D2)

PADS:

140343749(B9D2)

BBUF:

121009591(B9D2)

BGAR:

122919407 122919468(B9D2) 122919575

DTC:	141051984(B9D2)

PCOB:

134947869(B9D2)

PWL:	138259659(B9D2) 138278745 138278746 138304484

MUO:	115480336(B9D2) 115480765

GSH:	117364500(B9D2)

DRE:	436667(b9d2)

SRX:	107706523 107754962

SANH:

107681120 107703500

SGH:	107573061 107589303

CCAR:

109047286 109055146

CAUA:

113038656 113064251

CGIB:

127941907 127985946

PTET:

122326183(b9d2)

LROH:

127152302(b9d2)

GRF:	141292190(b9d2)

OMC:	131528710(b9d2)

PPRM:

120490764(b9d2)

RKG:	130096546(b9d2)

MAMB:

125252549(b9d2)

CIDE:

127504197

MASI:

127430998

TROS:

130570480(b9d2)

TDW:	130408156(b9d2)

MANU:

129423627(b9d2)

IPU:

108279395

IFU:	128622836(b9d2)

PHYP:

113541585(b9d2)

SMEO:

124397912(b9d2)

TFD:	125139832(b9d2)

TVC:	132860480(b9d2)

CGAR:

128507549(b9d2)

NGRA:

132894941(b9d2)

TRN:	134330171(b9d2)

AMEX:

103043513(b9d2)

CMAO:

118819845(b9d2)

EEE:	113573816(b9d2)

CHAR:

105904458(b9d2)

SPIL:

134079807(b9d2)

ASAD:

121709040(b9d2)

TRU:	115248887(b9d2)

TFS:	130540263(b9d2)

TNG:	GSTEN00027612G001

LCO:	104931399(b9d2)

NCC:	104948609(b9d2)

TBEN:

117486589(b9d2)

CGOB:

115008746(b9d2)

PGEO:

117447300(b9d2)

GACU:

117547532(b9d2)

EMAC:

134883222(b9d2)

ELY:	117256279(b9d2)

EFO:	125892369(b9d2)

PLEP:

121950660(b9d2)

SLUC:

116051558(b9d2)

ECRA:

117943046(b9d2)

ESP:	116687437(b9d2)

PFLV:

114554052(b9d2)

GAT:	120834990(b9d2)

PPUG:

119230006(b9d2)

AFB:	129105761(b9d2)

CLUM:

117731096(b9d2)

PSWI:

130208783(b9d2)

CANA:

137796794(b9d2)

CVE:	137873508(b9d2)

MSAM:

119886632(b9d2)

SCHU:

122864358(b9d2)

EARM:

139283450(b9d2)

CUD:	121529206(b9d2)

SPUL:

138606522(b9d2)

LMIX:

132977328(b9d2)

HTC:	141796047(b9d2)

ALAT:

119021522(b9d2)

ASTR:

137595864(b9d2)

PKLU:

139218591(b9d2)

MZE:	101481137(b9d2)

ONL:	100691940(b9d2)

OAU:	116313652(b9d2)

OLA:	101158348(b9d2)

OML:	112144718(b9d2)

XMA:	102232178(b9d2)

XCO:	114136213(b9d2)

XHE:	116711167(b9d2)

PRET:

103464429(b9d2)

PFOR:

103136095(b9d2)

PLAI:

106947076(b9d2)

PMEI:

106908819(b9d2)

GAF:	122834101(b9d2)

PPRL:

129358154(b9d2)

CVG:	107102903(b9d2)

CTUL:

119787922(b9d2)

GMU:	124857276(b9d2)

NFU:	107385300(b9d2)

KMR:	108231531(b9d2)

ALIM:

106514718(b9d2)

NWH:	119412405(b9d2)

AOCE:

111578056(b9d2)

EJA:	138196453(b9d2)

BFRE:

138616533(b9d2)

MCEP:

125007368(b9d2)

CSEM:

103386367(b9d2)

POV:	109635598(b9d2)

SSEN:

122768707(b9d2)

SSOE:

131460239(b9d2)

HHIP:

117761148 117761149

HSP:	118105106 118105436

PPLT:

128425158 128459468

SMAU:

118309701(b9d2)

LCF:

108891058

SDU:	111223946(b9d2)

SLAL:

111670183(b9d2)

XGL:	120782949(b9d2)

HCQ:

109522653

SSCV:

125976887 125977397

SBIA:

133507125 133507780(b9d2)

PEE:	133409221(b9d2)

PTAO:

133483870(b9d2)

BPEC:

110168444(b9d2)

ENY:	140366028(b9d2)

MALB:

109971124(b9d2)

BSPL:

114856194(b9d2)

SJO:	128355541(b9d2)

SSCO:

133978038(b9d2)

TTY:	137181308(b9d2)

GMH:	115557246(b9d2)

SASA:

106563631 106603182

STRU:

115153716 115204364

OTW:	112228144 112230607

OMY:	110510050 110534056

OGO:	124006985 124007419(b9d2)

ONE:	115101393 115136414

OKI:	109873463 109874098(b9d2)

OKE:	118385640 118390428

OMM:	135544222 135550357

OCLA:

139388493 139418582

SALP:

111950864 111963675

SNH:

120021385

SFON:

129863200(b9d2)

CCLU:

121541233 121580240

ELS:	105010855(b9d2)

OEP:	134014097(b9d2)

SFM:	108924779(b9d2)

PKI:	111838016(b9d2)

AANG:

118235364(b9d2)

AROT:

135263953(b9d2)

CCOG:

133133970(b9d2)

LOC:	102686728(b9d2)

PSPA:

121304945(b9d2)

PSEX:

120538771(b9d2)

LCM:	102364669(B9D2)

CMK:	121852532(b9d2)

RTP:	109936506(b9d2)

CPLA:

122542843(b9d2)

CPUN:

140454514(b9d2)

HOC:	132836662(b9d2)

SCAU:

119957837(b9d2)

LERI:

129714202(b9d2)

HAKA:

140716501(b9d2)

BFO:

BBEL:

CIN:

SCLV:

CLEP:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG42730(B9d2)

DER:

26526926

DSE:

6613594

DSI:	Dsimw501_GD26014(Dsim_GD26014)

DYA:	Dyak_GE26464

DAN:

DSR:

DPO:

DPE:

DMN:

DWI:

DGR:

DMO:	Dmoj_GI17528

DAZ:

108611384

DNV:

115562562

DHE:

111602219

DVI:	6628972(B9d2)

CCAT:

BOD:

BDR:

RZE:

AOQ:

ALUD:

TDA:

SCAC:

LSQ:

CVJ:	135951589(B9d2)

GFS:

ECOE:

CLON:

HIS:

AGA:

ACOZ:

AARA:

AMER:

ASTE:

AMAP:

AFUN:

AMOU:

AMRS:

ANIL:

AALI:

ADAR:

ACOS:

AAG:

AALB:

ASUA:

CQU:	CpipJ_CPIJ000916 CpipJ_CPIJ003360 CpipJ_CPIJ010076 CpipJ_CPIJ012191 CpipJ_CPIJ013550 CpipJ_CPIJ018449

CPII:

120413260 120415971 120415998 120420563

CBRI:

CNS:

LLL:

PPAP:

ACER:

ALAB:

MGEN:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

VEM:

COBS:

TAME:

HST:

DQU:

CFO:

PMEC:

PGC:

PCF:

PFUC:

VPS:

VCRB:

VVE:

LHT:

LBD:

CGLO:

CTYP:

DAM:

AGIF:

CINS:

VCAN:

DSM:

NPT:

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

ESIM:

136415662(B9d2)

EFOR:

136344381(B9d2)

RFG:	143198731(B9d2)

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

PPYR:

MSEX:

MCIX:

PMAC:

PPOT:

PNAP:

ZCE:

CCRC:

LSIN:

TNL:

SLIU:

PXY:

CFEL:

CCRN:

API:

DNX:

AGS:

RMD:

ACOO:

BTAB:

CLEC:

HHAL:

106686001(B9d2)

NLU:

111043603

LDA:	142319128 142324717 142327044

HVI:

MQU:

FOC:

TPAL:

ZNE:

CSEC:

PAME:

SGRE:

BROR:

FCD:

DPX:	DAPPUDRAFT_97802

DMK:

116923019

DPZ:

124341367

AFRA:

136031054

PVM:	113812246(B9d2)

PJA:

122246814

PCHN:

125037016

HAME:

121872605

PCLA:

123759395(B9d2)

CQD:	128705170(B9d2)

PTRU:

SPRM:

ESN:

MNZ:

MRJ:	136850521(B9d2)

PORN:

139754650(B9d2)

HAZT:

OOT:

EAF:

LSM:

TCF:

PPOI:

DSV:

DALB:

135921708(B9d2)

RSAN:

RMP:

VDE:

VJA:

GOE:

DPTE:

DFR:

CVS:

PTEP:

ABRU:

UDV:

SDM:

LPOL:

PMEO:

CEL:	CELE_Y38F2AL.2(mksr-2)

CBR:	CBG_16827(Cbr-mksr-2)

CRQ:	GCK72_016096

NAI:	NECAME_00498

BMY:	BM_BM6433(Bma-mksr-2)

LOA:	LOAG_03643

TSP:

Tsp_02792

HRO:	HELRODRAFT_67914

LGI:	LOTGIDRAFT_192266

PVUL:

PCAN:

LSAX:

BARL:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:	111130775 111130892

OED:

MYI:

PMAX:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:

OSN:

LJP:

LAK:

SMM:	Smp_076860

SHX:	MS3_00004717(B9D2_1)

LLON:

135485258

NVE:	5496567 5518964

EPA:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

RES:

TAD:	TRIADDRAFT_52819

AQU:

100637493

CRE:	CHLRE_03g196050v5

VCN:	VOLCADRAFT_77509

MNG:

MNEG_8463

MIS:	MICPUN_93482

MPP:	MICPUCDRAFT_26511

MBR:	MONBRDRAFT_17074

SRE:	PTSG_02742

TGO:	TGME49_283765

TET:	TTHERM_00633350 TTHERM_01099210

PTM:	GSPATT00010648001 GSPATT00019571001 GSPATT00034796001

TPS:	THAPS_38153

AAF:	AURANDRAFT_15956 AURANDRAFT_34417 AURANDRAFT_72177 AURANDRAFT_7420

PIF:	PITG_07108 PITG_10133

PSOJ:

PHYSODRAFT_313677 PHYSODRAFT_418713

SPAR:

SPRG_00420 SPRG_11503

TBR:	Tb11.03.0750

TBG:	TbgDal_XI270

TCR:	503917.35 507093.75

LMA:	LMJF_25_0320

LIF:	LINJ_25_0330

LDO:	LDBPK_250330

LMI:	LMXM_25_0320

LMAT:

92515213(LSCM1_05228)

LBZ:	LBRM_25_0320

LPAN:

LPMP_250340

LOI:	92360293(LSCM4_04374)

LEIS:

94179684(GH5_04239)

LENR:

94172331(CUR178_05126)

LEIN:

94188088(JIQ42_04430)

PHET:

94290589(JKF63_04528)

NGR:	NAEGRDRAFT_30379

TVA:	4765812(TVAGG3_0350130) 4766027(TVAGG3_0173240) 5467027(TVAGG3_0999700)

SSAO:

94294075(SS50377_20052)

EHX:	EMIHUDRAFT_205908 EMIHUDRAFT_47120

GTT:	GUITHDRAFT_153660 GUITHDRAFT_88158

» show all

Reference

PMID:19208769

Authors

Bialas NJ, Inglis PN, Li C, Robinson JF, Parker JD, Healey MP, Davis EE, Inglis CD, Toivonen T, Cottell DC, Blacque OE, Quarmby LM, Katsanis N, Leroux MR

Title

Functional interactions between the ciliopathy-associated Meckel syndrome 1 (MKS1) protein and two novel MKS1-related (MKSR) proteins.

Journal

J Cell Sci 122:611-24 (2009)
DOI:10.1242/jcs.028621

Sequence

[hsa:80776] [cel:CELE_Y38F2AL.2]

Reference

PMID:18287022

Authors

Town T, Breunig JJ, Sarkisian MR, Spilianakis C, Ayoub AE, Liu X, Ferrandino AF, Gallagher AR, Li MO, Rakic P, Flavell RA

Title

The stumpy gene is required for mammalian ciliogenesis.

Journal

Proc Natl Acad Sci U S A 105:2853-8 (2008)
DOI:10.1073/pnas.0712385105

Sequence

[hsa:80776] [mmu:232987]

LinkDB

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