KEGG ORTHOLOGY: K16808

ORTHOLOGY: K16808

Entry

K16808                      KO

Symbol

NUMA1

Name

nuclear mitotic apparatus protein 1

Disease

H02542

Acute promyelocytic leukemia

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K16808  NUMA1; nuclear mitotic apparatus protein 1
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Centrosome formation proteins
   Spindle formation proteins
    K16808  NUMA1; nuclear mitotic apparatus protein 1

Genes

HSA:	4926(NUMA1)

PTR:	451398(NUMA1)

PPS:	100995744(NUMA1)

GGO:	101145498(NUMA1)

PON:	100439501(NUMA1)

PPYG:

129008176(NUMA1)

NLE:	100597582(NUMA1)

HMH:	116476627(NUMA1)

SSYN:

129484561(NUMA1)

MCC:	718231(NUMA1)

MCF:	102138526(NUMA1)

MTHB:

126935011

MNI:	105468693(NUMA1)

CSAB:

103247986(NUMA1)

CATY:

105578907(NUMA1)

PANU:

100997993(NUMA1) 116272853

TGE:	112606435(NUMA1)

MLEU:

105549241(NUMA1)

RRO:	104665157(NUMA1)

RBB:	108543735(NUMA1)

TFN:	117081477(NUMA1)

PTEH:

111540898(NUMA1)

CANG:

105522305(NUMA1)

CJC:	100412992(NUMA1)

SBQ:	101052097(NUMA1)

CIMI:

108307514(NUMA1)

ANAN:

105720376(NUMA1)

CSYR:

103268501(NUMA1)

MMUR:

105860323(NUMA1)

LCAT:

123641085(NUMA1)

ERUF:

138385186(NUMA1)

PCOQ:

105811487(NUMA1)

OGA:	100945291(NUMA1)

MMU:	101706(Numa1)

MCAL:

110297463(Numa1)

MPAH:

110313178(Numa1)

RNO:	308870(Numa1)

MCOC:

116102677(Numa1)

ANU:	117698380(Numa1)

ASYL:

127664366(Numa1)

MUN:	110557559(Numa1)

CGE:	100762458(Numa1)

MAUA:

101844561(Numa1)

PROB:

127228001(Numa1)

PLEU:

114706628(Numa1)

PMAV:

102914592(Numa1)

MORG:

121463620(Numa1)

MFOT:

126488827

AAMP:

119810025(Numa1)

CNL:	130879100(Numa1)

NGI:	103750815(Numa1)

HGL:	101700873(Numa1)

CPOC:

100714541(Numa1)

CCAN:

109684518(Numa1)

DORD:

105983929(Numa1)

DSP:	122114263(Numa1)

DMER:

138836442(Numa1)

PLOP:

125361188(Numa1)

NCAR:

124958181

MMMA:

107135559(Numa1)

ITI:	101964646(Numa1)

OCU:	100302677(NUMA1)

OPI:	101532393(NUMA1)

OCZ:	121145420(NUMA1)

TUP:	102497033(NUMA1)

GVR:	103585880(NUMA1)

CFA:	485213(NUMA1)

CLUD:

112667465(NUMA1)

VVP:	112928696(NUMA1)

VLG:	121476283(NUMA1)

NPO:	129506679(NUMA1)

AML:	100476259(NUMA1)

UMR:	103678015(NUMA1)

UAH:	113269257(NUMA1)

UAR:	123782538(NUMA1)

ELK:

111159647

LLV:

125078300

MPUF:

101688910(NUMA1)

MNP:	132023724(NUMA1)

MLK:	131807918(NUMA1)

NVS:	122912622(NUMA1)

ORO:	101363362(NUMA1)

EJU:	114218690(NUMA1)

ZCA:	113915111(NUMA1)

MLX:	118003893(NUMA1)

MANO:

123857462(NUMA1)

NSU:	110593353(NUMA1)

LWW:	102733119(NUMA1)

FCA:	101096349(NUMA1)

PYU:	121039217(NUMA1)

PCOO:

112865736(NUMA1)

PBG:	122483386(NUMA1)

PVIV:

125177078(NUMA1)

LRUF:

124505321

LGF:	123601216(NUMA1)

AJU:

106966092

PTG:	102973013(NUMA1)

PPAD:

109267123(NUMA1)

PUC:

125937027

PLEZ:

122199353(NUMA1)

HHV:	120245118(NUMA1)

CCRU:

144230016(NUMA1)

BTA:	513091(NUMA1)

BOM:	102274997(NUMA1)

BIU:	109569217(NUMA1)

BBUB:

102394918(NUMA1)

BKE:	129629157(NUMA1)

BBIS:

104995563(NUMA1)

CHX:	102171630(NUMA1)

OAS:	101119246(NUMA1)

BTAX:

128060842(NUMA1)

CSUM:

138092351(NUMA1)

ODA:	120876716(NUMA1)

CCAD:

122449546(NUMA1)

MREE:

136174273(NUMA1)

OVR:	110131311(NUMA1)

MBEZ:

129554622(NUMA1)

SSC:	100526064(NUMA1)

CFR:	102517941(NUMA1)

CBAI:

105083279(NUMA1)

CDK:	105096640(NUMA1)

VPC:	102539975(NUMA1)

BACU:

103020294(NUMA1)

BMUS:

118898769(NUMA1)

LVE:	103087391(NUMA1)

OOR:	101272384(NUMA1)

LALB:

132526084(NUMA1)

GMF:	115839475(NUMA1)

DDP:	132429711(NUMA1)

DLE:	111170563(NUMA1)

PCAD:

102995505(NUMA1)

PSIU:

116757463(NUMA1)

PPHC:

136126937(NUMA1)

NASI:

112390743(NUMA1)

ECB:	100052884(NUMA1)

EPZ:	103549347(NUMA1)

EAI:	106831648(NUMA1)

MYB:	102256998(NUMA1)

MYD:	102751498(NUMA1)

MMYO:

118664703(NUMA1)

MLF:	102417938(NUMA1)

MDT:	132240850(NUMA1)

MYUM:

139017298(NUMA1)

PKL:	118713429(NUMA1)

EFUS:

103293659(NUMA1)

MNA:	107541146(NUMA1)

DRO:	112316096(NUMA1)

SHON:

119002654(NUMA1)

AJM:	119042097(NUMA1)

PDIC:

114498492(NUMA1)

PHAS:

123805644(NUMA1)

MMF:	118627668(NUMA1)

PPAM:

129072714(NUMA1)

HAI:	109372418(NUMA1)

RFQ:	117030232(NUMA1)

PALE:

102891874(NUMA1)

PGIG:

120590290(NUMA1)

PVP:	105303662(NUMA1)

RAY:	107517360(NUMA1)

MJV:	108405086(NUMA1)

TOD:	119255587(NUMA1)

SARA:

101542976(NUMA1)

SFUM:

130025307(NUMA1)

SETR:

126018125(NUMA1)

LAV:	100666019(NUMA1)

TMU:

101351082

ETF:	101640600(NUMA1)

DNM:	101413777(NUMA1)

MDO:	100015927(NUMA1)

GAS:	123240486(NUMA1)

SHR:	100930865(NUMA1)

AFZ:

127555254

PCW:	110195204(NUMA1)

TVP:	118835955(NUMA1)

PBRV:

138143445(NUMA1)

MLAO:

141508568(NUMA1)

OAA:	100088311(NUMA1)

TACU:

119945945(NUMA1)

GGA:	768717(NUMA1)

PCOC:

116233911(NUMA1)

MGP:	100542302(NUMA1)

CJO:	107308516(NUMA1)

TPAI:

128074965(NUMA1)

LMUT:

125696125(NUMA1)

NMEL:

110391606(NUMA1)

APLA:

119716806(NUMA1)

AACU:

137856440(NUMA1)

OJA:	118169412(NUMA1)

ACYG:

106029429(NUMA1)

CATA:

118259752(NUMA1)

AFUL:

116500912(NUMA1)

TGU:	100226780(NUMA1)

LSR:	110473096(NUMA1)

SCAN:

103820751(NUMA1)

PMOA:

120513381(NUMA1)

OTC:	121345415(NUMA1)

PRUF:

121354709(NUMA1)

ATRC:

139593019(NUMA1)

GFR:	102032973(NUMA1)

FAB:	101815825(NUMA1)

OMA:	130259187(NUMA1)

PHI:

102105434

PMAJ:

107203804

CCAE:

111940796

CCW:	104687167(NUMA1)

CBRC:

103613977(NUMA1)

ACOE:

138114311(NUMA1)

ETL:	114059627(NUMA1)

ZAB:	102065584(NUMA1)

ZLE:	135454096(NUMA1)

ACHL:

103807560

SVG:	106856596(NUMA1)

MMEA:

130579883(NUMA1)

HRT:	120747594(NUMA1)

SATI:

136375234(NUMA1)

CCIC:

134058222(NUMA1)

FPG:	101917496(NUMA1)

FCH:

102057664

SHAB:

115603637(NUMA1)

ACUN:

113476008(NUMA1)

TALA:

116963728(NUMA1)

ACHC:

115353224(NUMA1)

HLE:	104837506(NUMA1)

AGEN:

126048272

HHAR:

128153287(NUMA1)

BBUT:

142041467(NUMA1)

GCL:

127028684

DPUB:

104302278(NUMA1)

PPUS:

135175767(NUMA1)

EGZ:

104133708

NNI:	104011875(NUMA1)

PARX:

142061158(NUMA1)

AFOR:

103908492

CBOR:

142077998(NUMA1)

CBOY:

140646686(NUMA1)

MAME:

142404490(NUMA1)

CLV:	102098407(NUMA1)

CNIC:

135988698(NUMA1)

CUCA:

104062205(NUMA1)

CPEA:

104385319

CVF:	104286753(NUMA1)

RTD:	128904899(NUMA1)

CRID:

134512602(NUMA1)

LMIC:

141737475(NUMA1)

AAM:

106483916

AROW:

112961374(NUMA1)

DNE:	112993982(NUMA1)

SCAM:

104143306(NUMA1)

ASN:	102382699(NUMA1)

AMJ:	102569979(NUMA1)

CPOO:

109306857(NUMA1)

GGN:	109302656(NUMA1)

PSS:	102449000(NUMA1)

CIZ:	142023787(NUMA1)

CMY:	102943307(NUMA1)

CCAY:

125631496(NUMA1)

LKP:	140907437(NUMA1)

NDS:	141988524(NUMA1)

DCC:	119851111(NUMA1)

CPIC:

101948388(NUMA1)

TST:	117871348(NUMA1)

CABI:

116832137(NUMA1)

MRV:	120396052(NUMA1)

ACS:	100566838(numa1)

ASAO:

132772324(NUMA1)

PVT:	110078122(NUMA1)

SUND:

121925670(NUMA1)

PBI:	103062409(NUMA1)

PMUR:

107299627(NUMA1)

CTIG:

120320229(NUMA1)

TSR:	106541656(NUMA1)

PGUT:

117676439(NUMA1)

PCAE:

139316365(NUMA1)

APRI:

131199459(NUMA1)

PTEX:

113451117(NUMA1)

NSS:	113430558(NUMA1)

VKO:	123017283(NUMA1)

PMUA:

114595495(NUMA1)

PRAF:

128412443(NUMA1)

ZVI:	118085784(NUMA1)

HCG:	128349306(NUMA1)

GJA:	107113640(NUMA1)

EMC:	129326541(NUMA1)

XLA:	397920(numa1.S) 443581(numa1.L)

XTR:	100145664(numa1)

NPR:	108802510(NUMA1)

RTEM:

120921596(NUMA1)

ACAT:

141126689(NUMA1)

PADS:

140323313(NUMA1)

BBUF:

120996576(NUMA1)

BGAR:

122932357(NUMA1)

DTC:	141051515(NUMA1)

PWL:	138249722(NUMA1)

MUO:	115468335(NUMA1)

GSH:	117362526(NUMA1)

DRE:	572344(numa1)

SRX:	107706062 107731821

SANH:

107669921 107670062

SGH:	107558821 107560838

CCAR:

109066081 109082335

CAUA:

113058882 113081244 113114705(numa1)

CGIB:

127972435 128029063

PTET:

122359028(numa1)

LROH:

127177078(numa1)

OMC:	131520385(numa1)

PPRM:

120470794

RKG:	130101180(numa1)

MAMB:

125248558

CIDE:

127495709

CERY:

137004315(numa1)

MASI:

127422578 127430120

TROS:

130565127(numa1)

TDW:	130429062(numa1)

MANU:

129438666(numa1)

PDAB:

135770703(numa1)

IPU:

108278230

IFU:	128621687(numa1)

PHYP:

113544592

SMEO:

124394550(numa1)

TFD:	113636450 113637880(numa1) 113650586

TVC:	132858495(numa1)

CGAR:

128533196(numa1)

NGRA:

132900934(numa1)

TRN:	134334705(numa1)

CMAO:

118798766(numa1)

EEE:	113578704(numa1)

SPIL:

134099270(numa1)

TRU:	105417044(numa1)

TFS:	130535546(numa1)

LCO:	104920124(numa1)

TBEN:

117470260(numa1)

CGOB:

115017405(numa1)

PGEO:

117457712(numa1)

GACU:

117534904(numa1)

EMAC:

134880635(numa1)

ELY:

117260263

EFO:	125889371(numa1)

PLEP:

121943290(numa1)

SLUC:

116045556(numa1)

ECRA:

117938632(numa1)

ESP:	116687069(numa1)

PFLV:

114552514(numa1)

GAT:	120827129(numa1)

PPUG:

119216688(numa1)

AFB:	129109656(numa1)

CLUM:

117741108(numa1)

PSWI:

130211369(numa1)

CANA:

137790443(numa1)

CVE:

137871584

MSAM:

119883122(numa1) 119916747

SCHU:

122879433(numa1)

EARM:

139285410

CUD:	121522406(numa1)

SPUL:

138596696

LMIX:

132980308(numa1)

HTC:

141797696

ALAT:

119032865(numa1)

ASTR:

137596829(numa1)

PKLU:

139199865(numa1)

MZE:

101482661

ONL:	100706456(numa1)

OAU:	116322095(numa1)

OLA:	101165245(numa1)

OML:	112149341(numa1)

CSAI:

133441680(numa1)

XMA:	102230200(numa1)

XCO:	114161837(numa1)

XHE:	116708086(numa1)

PRET:

103474480(numa1)

PFOR:

103146271(numa1)

PLAI:

106958864(numa1)

PMEI:

106927834(numa1)

GAF:	122832958(numa1)

PPRL:

129358903(numa1)

CVG:	107091939(numa1)

CTUL:

119771772(numa1)

GMU:	124883688(numa1)

NFU:	107380462(numa1)

KMR:	108244642(numa1)

ALIM:

106517261(numa1)

NWH:	119411530(numa1)

AOCE:

111570897(numa1)

EJA:

138197508

BFRE:

138616469

CSEM:

103378564(numa1)

POV:	109634415(numa1)

SSEN:

122773634(numa1)

SSOE:

131462552(numa1)

HHIP:

117773030(numa1)

HSP:	118106375(numa1)

PPLT:

128440743(numa1)

SMAU:

118298978(numa1)

LCF:

108886612

SDU:	111224044(numa1)

SLAL:

111655301(numa1)

XGL:	120791936(numa1)

HCQ:	109525427(numa1)

SBIA:

133505330(numa1)

PEE:	133405407(numa1)

PTAO:

133482244(numa1)

BPEC:

110174448(numa1)

ENY:	140375324(numa1)

MALB:

109971601(numa1)

BSPL:

114867548(numa1)

SJO:	128359966(numa1)

SSCO:

133980278(numa1)

TTY:	137185963(numa1)

GMH:	115560635(numa1)

SASA:

106613229(numa1)

STRU:

115206589(numa1)

OTW:	112267295(numa1)

OMY:	110503183(numa1)

OGO:	124005130(numa1)

ONE:

115141993

OKI:	109909497(numa1)

OKE:	118394480(numa1)

OMM:	135546658(numa1)

OCLA:

139382878

SALP:

112071325(numa1)

SNH:	120028610(numa1)

SFON:

129831710(numa1)

ELS:	105024060(numa1)

OEP:	134029603(numa1)

SFM:	108932226(numa1)

PKI:	111833856(numa1)

AANG:

118210389(numa1)

AROT:

135235804(numa1)

CCOG:

133108434(numa1)

LOC:	102691667(numa1)

PSPA:

121302868(numa1)

ARUT:

117406012 117972843

LCM:	102358517(NUMA1)

CMK:	103190885(numa1)

RTP:	109936823(numa1)

CPLA:

122550970(numa1)

CPUN:

140481088

HOC:	132816579(numa1)

SCAU:

119977262(numa1)

LERI:

129694731(numa1)

HAKA:

BBEL:

SCLV:

Reference

PMID:20137953

Authors

Radulescu AE, Cleveland DW

Title

NuMA after 30 years: the matrix revisited.

Journal

Trends Cell Biol 20:214-22 (2010)
DOI:10.1016/j.tcb.2010.01.003

Sequence

[hsa:4926]

Reference

PMID:19255246

Authors

Silk AD, Holland AJ, Cleveland DW

Title

Requirements for NuMA in maintenance and establishment of mammalian spindle poles.

Journal

J Cell Biol 184:677-90 (2009)
DOI:10.1083/jcb.200810091

Sequence

[hsa:4926]

LinkDB

DBGET integrated database retrieval system