KEGG ORTHOLOGY: K16862

ORTHOLOGY: K16862

Entry

K16862                      KO

Symbol

PLD6

Name

mitochondrial cardiolipin hydrolase [EC:3.1.4.-]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03036 Chromosome and associated proteins
    K16862  PLD6; mitochondrial cardiolipin hydrolase
   03029 Mitochondrial biogenesis
    K16862  PLD6; mitochondrial cardiolipin hydrolase
Chromosome and associated proteins [BR:ko03036]
Eukaryotic type
  Gene silencing
   piRNA pathway
    K16862  PLD6; mitochondrial cardiolipin hydrolase
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial quality control factors
  Mitochondrial dynamics
   Fission and Fusion factors
    K16862  PLD6; mitochondrial cardiolipin hydrolase

Other DBs

GO:

0035755

Genes

HSA:	201164(PLD6)

PTR:	454471(PLD6)

PPS:	100969225(PLD6)

GGO:	101142630(PLD6)

PON:	100433490(PLD6)

PPYG:

129018059(PLD6)

NLE:	100588249(PLD6)

HMH:	116476709 116483423(PLD6)

SSYN:

129461668(PLD6)

MCC:	703931(PLD6)

MCF:	102130404(PLD6)

MTHB:

126938824

MNI:	105491073(PLD6)

CSAB:

103242466(PLD6)

CATY:

105598189(PLD6)

PANU:

101008107(PLD6)

TGE:	112609662(PLD6)

MLEU:

105536031(PLD6)

RRO:	104668267(PLD6)

RBB:	108544474(PLD6)

TFN:	117067589(PLD6)

PTEH:

111529221(PLD6)

CANG:

105518998(PLD6)

CJC:	100395827(PLD6)

SBQ:	101033069(PLD6)

CIMI:

108295286(PLD6)

ANAN:

105709858(PLD6)

MMUR:

105856330(PLD6)

LCAT:

123620180(PLD6)

PCOQ:

105816083(PLD6)

OGA:	100954147(PLD6)

MMU:	194908(Pld6)

MCAL:

110305301(Pld6)

MPAH:

110332712(Pld6)

RNO:	287366(Pld6)

MCOC:

116077776(Pld6)

ANU:	117710188(Pld6)

ASYL:

127695243(Pld6)

MUN:	110550008(Pld6)

CGE:

113836808

MAUA:

101823623(Pld6)

PROB:

127219213(Pld6)

PLEU:

114682580(Pld6)

PMAV:

102920383(Pld6)

MORG:

121456768(Pld6)

MFOT:

126514605

AAMP:

119813033(Pld6)

NGI:	103743384(Pld6)

HGL:	101713335(Pld6)

CPOC:

100726923(Pld6)

CCAN:

109698423(Pld6)

DORD:

105985763(Pld6)

DSP:	122103296(Pld6)

DMER:

138830401(Pld6)

PLOP:

125365109(Pld6)

NCAR:

124979047

MMMA:

107157170(Pld6)

ITI:	101961957(Pld6)

OCU:

103346090

OCZ:	121152463(PLD6) 121167538

TUP:	102480357(PLD6)

GVR:	103600029(PLD6)

CFA:	489545(PLD6)

CLUD:

112647232(PLD6)

VVP:	112925016(PLD6)

VLG:	121500629(PLD6)

NPO:	129496890(PLD6)

AML:	100469969(PLD6)

UMR:	103658488(PLD6)

UAH:	113271308(PLD6)

UAR:	123779766(PLD6)

ELK:

111139222

LLV:

125087526

MPUF:

101683857(PLD6)

MNP:	132003377(PLD6)

MLK:	131816843(PLD6)

NVS:	122907392(PLD6)

ORO:	101381186(PLD6)

EJU:	114198227(PLD6)

ZCA:	113939845(PLD6)

MLX:	117999885(PLD6)

NSU:	110584699(PLD6)

LWW:	102750657(PLD6)

FCA:	101088529(PLD6)

PYU:	121015794(PLD6)

PCOO:

112857150(PLD6)

PBG:	122485061(PLD6)

PVIV:

125152204(PLD6)

LRUF:

124519492

LGF:	123603133(PLD6)

AJU:

106981382

PTG:	102954877(PLD6)

PPAD:

109245758(PLD6)

PUC:

125927552

PLEZ:

122206719(PLD6)

HHV:	120228789(PLD6)

BTA:	526651(PLD6)

BOM:	102268607(PLD6)

BIU:	109573476(PLD6)

BBUB:

102393205(PLD6)

BBIS:

104990849(PLD6)

CHX:	102184373(PLD6)

OAS:	101113688(PLD6)

BTAX:

128065659(PLD6)

CSUM:

138082659(PLD6)

ODA:	120867372(PLD6)

CCAD:

122445040(PLD6)

MREE:

136149490(PLD6)

OVR:	110150995(PLD6)

MBEZ:

129537216(PLD6)

SSC:	110256141(PLD6)

CFR:	102504034(PLD6)

CBAI:

105084171(PLD6)

CDK:	105100591(PLD6)

VPC:	102537509(PLD6)

BACU:

103020299(PLD6)

BMUS:

118887405(PLD6)

LVE:	103069334(PLD6)

OOR:	101276828(PLD6)

LALB:

132511406(PLD6)

GMF:	115855736(PLD6)

DDP:	138413849(PLD6)

DLE:	111167698(PLD6)

PCAD:

102979182(PLD6)

PSIU:

116746449(PLD6)

PPHC:

136138970(PLD6)

NASI:

112405394(PLD6)

ECB:	100052895(PLD6)

EPZ:	103566548(PLD6)

EAI:	106840707(PLD6)

MYD:	102766776(PLD6)

MMYO:

118649332(PLD6)

MLF:	102416929(PLD6)

MDT:	132219258(PLD6)

MYUM:

138994687(PLD6)

PKL:	118726872(PLD6)

EFUS:

103299387(PLD6)

DRO:	112308876(PLD6)

SHON:

119002766(PLD6)

AJM:	119062285(PLD6)

PDIC:

114515159(PLD6)

PHAS:

123809468(PLD6)

MMF:	118641286(PLD6)

PPAM:

129068680(PLD6)

HAI:	109390314(PLD6)

RFQ:	117013555(PLD6)

PALE:

102892333(PLD6)

PGIG:

120589883(PLD6)

PVP:	105304158(PLD6)

RAY:	107506749(PLD6)

MJV:	108391546(PLD6)

TOD:	119230966(PLD6)

SARA:

101546817(PLD6)

SFUM:

130044264(PLD6)

SETR:

126013749(PLD6)

LAV:	100676742(PLD6)

TMU:

101341416

DNM:	101417355(PLD6) 105744328

MDO:	100009827(PLD6)

GAS:	123231309(PLD6)

SHR:	100934329(PLD6)

AFZ:

127562078

PCW:	110194784(PLD6)

TVP:	118833890(PLD6)

PBRV:

138161110(PLD6)

MLAO:

141502328(PLD6)

OAA:	100080092(PLD6)

TACU:

119942138(PLD6)

GGA:	107054610(PLD6)

PCOC:

116237684(PLD6)

MGP:	116217227(PLD6)

CJO:	107320599(PLD6)

TPAI:

128079399(PLD6)

LMUT:

125701000(PLD6)

NMEL:

110405817(PLD6)

APLA:

113845233(PLD6)

ACYG:

106032182(PLD6)

CATA:

118256376(PLD6)

AFUL:

116495329(PLD6)

TGU:	115497276(PLD6)

LSR:	110481592(PLD6)

SCAN:

103817844(PLD6)

PMOA:

120512970(PLD6)

OTC:	121334443(PLD6)

PRUF:

121350622(PLD6) 121351031

ATRC:

139598010(PLD6)

GFR:	102034128(PLD6)

FAB:	101817097(PLD6)

OMA:	130259509(PLD6)

PHI:	102107420(PLD6)

PMAJ:

107210982(PLD6)

CCAE:

111936138(PLD6)

CCW:	104684783(PLD6)

ACOE:

138118934(PLD6)

ETL:	114065972(PLD6)

ZLE:	135454160(PLD6)

SVG:	106863421(PLD6)

HRT:	120759811(PLD6)

SATI:

136368250(PLD6)

CCIC:

134050656(PLD6)

FCH:	106630917(PLD6)

SHAB:

115606435(PLD6)

ACHC:

115335876(PLD6)

HLE:	104833719(PLD6)

AGEN:

126034103

HHAR:

128134856(PLD6)

GCL:

127022544

LDI:	104351017(PLD6)

PPUS:

135180381(PLD6)

EGZ:	104123101(PLD6)

CBOR:

142089464(PLD6)

CBOY:

140659118(PLD6)

MAME:

142415841(PLD6)

CNIC:

135994324(PLD6)

MUI:	104546618(PLD6)

PGUU:

104462461(PLD6)

CUCA:

128853725(PLD6)

ACAR:

104526398(PLD6)

CPEA:

104385292(PLD6)

RTD:	128913355(PLD6)

CRID:

134519329(PLD6)

LMIC:

141747463(PLD6)

AROW:

112974223(PLD6)

NPD:	112959813(PLD6)

DNE:	112980358(PLD6)

ASN:	102370470(PLD6)

AMJ:	109284904(PLD6)

CPOO:

109314808(PLD6)

GGN:	109294269(PLD6)

CIZ:	142021675(PLD6)

CMY:	119567162(PLD6)

CCAY:

125643463(PLD6)

DCC:	119862442(PLD6)

CPIC:

101949640(PLD6)

TST:	117883830(PLD6)

CABI:

116814858(PLD6)

MRV:	120374116(PLD6)

ACS:	103280783(pld6)

ASAO:

132782130(PLD6)

PVT:	110071097(PLD6)

SUND:

121914846(PLD6)

PBI:	103055400(PLD6)

PMUR:

107289131(PLD6)

CTIG:

120319314(PLD6)

PGUT:

117679427(PLD6)

PCAE:

139325210(PLD6)

APRI:

131185094(PLD6)

PTEX:

113438977(PLD6)

NSS:	113422426(PLD6)

VKO:	123025140(PLD6)

PMUA:

114584814(PLD6)

PRAF:

128401798(PLD6)

ZVI:	118092928(PLD6)

HCG:	128336458(PLD6)

GJA:	107124230(PLD6)

STOW:

125431389(PLD6)

EMC:	129339073(PLD6)

XLA:	100037063(pld6.S)

XTR:	549629(pld6)

NPR:

108796257

RTEM:

120942608(PLD6)

ACAT:

141148679(PLD6)

PADS:

140335056(PLD6)

BBUF:

121008338(PLD6)

BGAR:

122945507(PLD6)

DTC:	141069154(PLD6)

PWL:	138261269(PLD6)

MUO:	115461975 115475939(PLD6)

GSH:	117345840(PLD6)

DRE:	567338(pld6)

SRX:	107747428 107757003

SANH:

107676262 107694824

SGH:	107569524 107583251

CCAR:

109051488(pld6)

CAUA:

113043943 113043975

CGIB:

127949049

PTET:

122350321(pld6)

LROH:

127169448(pld6)

GRF:	141335971(pld6)

OMC:	131544201(pld6)

PPRM:

120460569(pld6)

RKG:	130079907(pld6)

MAMB:

125271871(pld6)

CIDE:

127512177

CERY:

137032368(pld6)

MASI:

127445041

TROS:

130553480(pld6)

TDW:	130410098(pld6)

MANU:

129444068(pld6)

PDAB:

135786133(pld6)

IPU:

108258502

IFU:	128602522(pld6)

PHYP:

113537601(pld6)

SMEO:

124378112(pld6)

TFD:	113648865(pld6)

TVC:	132839615(pld6)

CGAR:

128506829(pld6)

NGRA:

132865782(pld6)

TRN:	134328224(pld6)

AMEX:

103033815(pld6)

CMAO:

118804351(pld6)

SPIL:

134076398(pld6)

ASAD:

121719579(pld6)

TRU:	101074591(pld6)

TFS:	130527194(pld6)

TNG:	GSTEN00011500G001

LCO:	104926673(pld6)

NCC:	104950518(pld6)

TBEN:

117482368(pld6)

CGOB:

115009230(pld6)

PGEO:

117446347(pld6)

GACU:

117537975(pld6)

EMAC:

134865126(pld6)

ELY:	117254682(pld6)

EFO:	125885511(pld6)

PLEP:

121941991(pld6) 121963562

SLUC:

116040520(pld6)

ECRA:

117958018(pld6)

ESP:	116702949(pld6)

PFLV:

114547581(pld6)

GAT:	120825728(pld6)

PPUG:

119218142(pld6)

AFB:	129095806(pld6)

CLUM:

117734641(pld6)

PSWI:

130190421(pld6)

CANA:

137794864(pld6)

CVE:	137885198(pld6)

MSAM:

119899219(pld6)

SCHU:

122872895(pld6)

CUD:	121509053(pld6)

SPUL:

138594391(pld6)

LMIX:

132991516(pld6)

HTC:	141808797(pld6)

ALAT:

119021361(pld6)

ASTR:

137600816(pld6)

MZE:	101465713(pld6)

ONL:	100691369(pld6)

OAU:	116321403(pld6)

OLA:	101173365(pld6)

OML:	112157324(pld6)

CSAI:

133452144(pld6)

XMA:	102216523(pld6)

XCO:	114144961(pld6)

XHE:	116720036(pld6)

PRET:

103468493(pld6)

PFOR:

103137737(pld6)

PLAI:

106961615(pld6)

PMEI:

106914873(pld6)

GAF:	122829012(pld6)

CVG:	107095698(pld6)

CTUL:

119788258(pld6)

GMU:	124868265(pld6)

NFU:	107382224(pld6)

KMR:	108244350(pld6)

ALIM:

106515168(pld6)

AOCE:

111574095(pld6)

EJA:	138209157(pld6)

BFRE:

138620244(pld6)

MCEP:

125004414(pld6)

CSEM:

103384162(pld6)

POV:	109627644(pld6)

SSEN:

122771210(pld6)

SSOE:

131466891(pld6)

HHIP:

117765020(pld6)

HSP:	118123701(pld6)

PPLT:

128436652(pld6)

SMAU:

118312869(pld6)

LCF:

108875900

SDU:	111237696(pld6)

SLAL:

111650955(pld6)

XGL:	120800816(pld6)

HCQ:	109511448(pld6)

SSCV:

125968844(pld6)

SBIA:

133506323(pld6)

PEE:	133404296(pld6)

PTAO:

133477133(pld6)

BPEC:

110172588(pld6)

ENY:	140377686(pld6)

MALB:

109958406(pld6)

BSPL:

114854456(pld6)

SJO:	128368237(pld6)

SSCO:

133990201(pld6)

TTY:	137174396(pld6)

GMH:	115540566(pld6)

SASA:

106589682 106590216

STRU:

115147351 115178820

OTW:	112247976(pld6)

OMY:	110487512 110487513

OGO:	124015094 124015314 124026761

OKI:	109882520 109882524

OKE:	118374691(pld6)

OMM:	135526299(pld6)

OCLA:

139423774

SALP:

112075102 112079186

SNH:	120032480(pld6) 120041747

SFON:

129835702(pld6)

CCLU:

121554017(pld6)

ELS:	105012156(pld6)

OEP:	134008875(pld6)

SFM:	108923821(pld6)

PKI:	111833553(pld6)

AANG:

118221448(pld6)

AROT:

135248940(pld6)

CCOG:

133122364(pld6)

LOC:	102693012(pld6)

PSPA:

121310199(pld6)

ARUT:

117402140 117409769

PSEX:

120541182(pld6)

LCM:	102362751(PLD6)

CMK:	103178675(pld6)

RTP:	125485678(pld6)

CPLA:

122560746(pld6)

CPUN:

140464751(pld6)

HOC:	132825606(pld6)

SCAU:

119979099(pld6)

LERI:

129706854(pld6)

HAKA:

140735117(pld6)

BFO:

BBEL:

SCLV:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

DME:	Dmel_CG12314(zuc)

DER:

6542904

DSE:

6617686

DSI:	Dsimw501_GD22146(Dsim_GD22146)

DYA:	Dyak_GE12577

DAN:	6496155 6497575

DSR:	110177967 110183982

DPO:

4817110

DPE:

6589693

DMN:

108162923

DWI:	6639691 6642584

DGR:	6559598 6566707

DMO:	Dmoj_GI10739 Dmoj_GI13482 Dmoj_GI21822 Dmoj_GI24814 Dmoj_GI26525

DAZ:	108611815 108615171 108619724 108620773

DNV:	108652879 115563366 115564174 115564918

DHE:	111593241 111594899 111597315 111603766

DVI:	6625619 6627863(zuc) 6633210 6633589

CCAT:

BOD:

BDR:

AOQ:

ALUD:

TDA:

MDE:

SCAC:

LCQ:

LSQ:

CVJ:	135956966(zuc)

GFS:	119631984 119633681 119641847

ECOE:

CLON:

HIS:

CBRI:

CNS:	116341852 116341938 116351939 116351940

BCOO:

LLL:

PPAP:

AME:

ACER:

ADR:

AFLR:

BIM:

BBIF:

BVAN:

BTER:

BPYO:

FVI:

CCAL:

OBB:

OLG:

MGEN:

NMEA:

CGIG:

SOC:

MPHA:

AEC:

ACEP:

ACOC:

MZT:	108726465(zuc)

CCOA:

TCZ:

TSEP:

PBAR:

VEM:

COBS:

139111114(Zuc)

TLN:	139822834(Zuc)

HST:

DQU:

CFO:

FEX:

PMEC:

138937868(Zuc)

LHU:	105674729(zuc)

PGC:

OBO:

PCF:

PFUC:

VPS:

VCRB:

VVE:

CSOL:

TPRE:

LHT:

MDL:

CGLO:

CTYP:

141527000(Zuc)

FAS:

DAM:

AGIF:

CINS:

VCAN:

CCIN:

DSM:

NPT:	124211369(zuc)

NFB:

NLO:

NVG:

AROA:

TCA:

TMOL:

138136937(zuc)

DPA:

ESIM:

EFOR:

SOY:

RFG:	143203742(zuc)

AGRG:

ATD:

CSET:

HAXR:

AGB:

LDC:

DVV:

NVL:

DCOR:

135793842(zuc)

APLN:

PPYR:

OTU:

BMOR:

BMAN:

MSEX:

115447892 115455382 119189441 119190994

DPL:	KGM_212319 KGM_213160

BANY:

112049704 112057035

MJU:	123868159 123881321

NIQ:	126774490 126777728

VCD:	124536359 124536548

MCIX:

123659821 123666095

PMAC:

106718905 106719660

PPOT:

106100268 106107872

PXU:	106117003 106121190

BPHI:

137919349 137929566

PRAP:

110995060 110999149

PBX:	123710355 123714796

PNAP:

125048911 125063319

ZCE:	119828236 119830280

CCRC:

123694143 123703656

LSIN:

126964690 126976558

AAGE:

121729471 121739379

HAW:	110373699 126055091

HZE:	124635107 124643253

TNL:	113494541 113497812

SLIU:

111353210 111359209

OFU:	114359761 114366256

ATRA:

106129339 106139928

GMW:	113519963 113522661

PXY:	105386567 125490957

PGW:	126372802 126380947

LGLY:

CSTB:

CFUM:

CCRN:

API:	100570917 100574569

DNX:	107165035 107171738

AGS:	114123345 114132019

RMD:	113554527 113557249

ACOO:

126843416 126844538

DVT:	126903359 126904249 126909929

BTAB:

109034033 109034200

CLEC:

106662877 106665986

HHAL:

106688453(zuc)

NLU:

111056296

LDA:	142326069(zuc)

HVI:

124353741

MQU:	129002786 129003110

PHU:	Phum_PHUM318600

TPAL:

117654277

ZNE:

110839239

CSEC:

111862780

PAME:

138713711(zuc)

SGRE:

126354473

BROR:

134538330

IEL:

124165565

HAMR:

139686784(zuc)

FCD:	110843101 110851230 110851830

DPX:	DAPPUDRAFT_308957 DAPPUDRAFT_64062

DMK:

116931828

DPZ:	124315982 124329480 124342208 124343068 124349137 124349998

AFRA:

136037750

EAF:	111697390 111697391

LSM:	121122988(zuc)

TCF:

PPOI:

ISC:

DSV:

DALB:

135898679(zuc)

RSAN:

119399720

RMP:

119179654

CSCU:

111628046 111634527

CVS:	136978646 136980382 136987172

PTEP:

ABRU:

SDM:

LPOL:

HRO:	HELRODRAFT_111094

LGI:	LOTGIDRAFT_155267

PVUL:

PCAN:

LSAX:

BGT:

GAE:

HRF:

HRJ:

HASI:

HCRA:

CRG:

CANU:

CVN:

OED:

MYI:

AIRR:

YBA:

MCAF:

MMER:

RPHI:

DPOL:

MAEA:

OBI:	106874083 106874085

OSN:	115227296 115231071

LJP:

LAK:

LLON:

NVE:

EPA:

ATEN:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

AQU:

CRE:	CHLRE_13g591900v5

VCN:	VOLCADRAFT_99461(pldA)

MNG:

MNEG_0227

OLU:	OSTLU_7664

BPG:	Bathy08g01390

MIS:	MICPUN_109205

MPP:	MICPUCDRAFT_47031

PIF:	PITG_01124

PSOJ:

PHYSODRAFT_308595

EHX:	EMIHUDRAFT_314734 EMIHUDRAFT_355894 EMIHUDRAFT_374088

» show all

Reference

PMID:21397848

Authors

Huang H, Gao Q, Peng X, Choi SY, Sarma K, Ren H, Morris AJ, Frohman MA

Title

piRNA-associated germline nuage formation and spermatogenesis require MitoPLD profusogenic mitochondrial-surface lipid signaling.

Journal

Dev Cell 20:376-87 (2011)
DOI:10.1016/j.devcel.2011.01.004

Sequence

[hsa:201164]

Reference

PMID:17543859

Authors

Pane A, Wehr K, Schupbach T

Title

zucchini and squash encode two putative nucleases required for rasiRNA production in the Drosophila germline.

Journal

Dev Cell 12:851-62 (2007)
DOI:10.1016/j.devcel.2007.03.022

Sequence

[dme:Dmel_CG12314]

LinkDB

DBGET integrated database retrieval system