KEGG   ORTHOLOGY: K17377
Entry
K17377            RNA       KO                                     
Symbol
MIR449
Name
microRNA 449
Pathway
map05206  MicroRNAs in cancer
Brite
KEGG Orthology (KO) [BR:ko00001]
 09160 Human Diseases
  09161 Cancer: overview
   05206 MicroRNAs in cancer
    K17377  MIR449; microRNA 449
 09180 Brite Hierarchies
  09183 Protein families: signaling and cellular processes
   04147 Exosome
    K17377  MIR449; microRNA 449
  09184 RNA family
   03100 Non-coding RNAs
    K17377  MIR449; microRNA 449
Exosome [BR:ko04147]
 Exosomal RNA
  Exosomal RNA of renal carcinoma cells
   K17377  MIR449; microRNA 449
Non-coding RNAs [BR:ko03100]
 Other eukaryotic RNA
  Micro RNA
   K17377  MIR449; microRNA 449
Genes
HSA: 100313923(MIR449C) 554213(MIR449A) 693123(MIR449B)
PTR: 100316169(MIR449B) 100316334(MIR449A) 101954230(MIR449C)
MCC: 100315408(MIR449A) 100315457(MIR449B)
MMU: 723868(Mir449a) 735309(Mir449c)
RNO: 100314068(Mir449a) 100526629(Mir449c)
CGE: 114483676(Mir449a)
OCU: 114483181(MIR449A) 114483185(MIR449B)
CFA: 100885868(MIR449A)
BTA: 100313050(MIR449B) 100313051(MIR449C) 100313264(MIR449A)
CHX: 104795837(MIR449A) 104795838(MIR449C) 104796579(MIR449B)
ECB: 100315020(MIR449A) 104795092(MIR449B)
EFUS: 104797175(MIR449)
MDO: 100034266(MIR449A) 104794554(MIR449B)
OAA: 100314507(MIR449C) 100314628(MIR449B) 100314717(MIR449A)
GGA: 100315796(MIR449C) 100315859(MIR449B) 777913(MIR449A)
ACS: 104794184(mir449a) 104794185(mir449b) 104794209(mir449c)
XTR: 100886868(mir449a) 100886879(mir449c) 100886956(mir449b)
 » show all
Reference
PMID:21857159
  Authors
Lize M, Klimke A, Dobbelstein M
  Title
MicroRNA-449 in cell fate determination.
  Journal
Cell Cycle 10:2874-82 (2011)
DOI:10.4161/cc.10.17.17181
Reference
PMID:35563522
  Authors
Vajen B, Bhowmick R, Greiwe L, Schaffer V, Eilers M, Reinkens T, Stalke A, Schmidt G, Fiedler J, Thum T, DeLuca DS, Hickson ID, Schlegelberger B, Illig T, Skawran B
  Title
MicroRNA-449a Inhibits Triple Negative Breast Cancer by Disturbing DNA Repair and Chromatid Separation.
  Journal
Int J Mol Sci 23:ijms23095131 (2022)
DOI:10.3390/ijms23095131
  Sequence
[hsa:554213]
Reference
PMID:24120948
  Authors
Martin A, Jones A, Bryar PJ, Mets M, Weinstein J, Zhang G, Laurie NA
  Title
MicroRNAs-449a and -449b exhibit tumor suppressive effects in retinoblastoma.
  Journal
Biochem Biophys Res Commun 440:599-603 (2013)
DOI:10.1016/j.bbrc.2013.09.117
  Sequence
[hsa:693123]
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