Entry
Symbol
ACO2
Name
homoaconitase [EC:4.2.1.-]
Pathway
map01110 Biosynthesis of secondary metabolites
map01120 Microbial metabolism in diverse environments
map01210 2-Oxocarboxylic acid metabolism
Module
M00030 Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00433 Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
Reaction
R03444 (R)-2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09105 Amino acid metabolism
00300 Lysine biosynthesis
K17450 ACO2; homoaconitase
Enzymes of 2-oxocarboxylic acid metabolism [br01601.html ]
2-Oxoacid chain elongation
K17450
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Reference
Authors
Fazius F, Shelest E, Gebhardt P, Brock M
Title
The fungal alpha-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate.
Journal
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