KEGG   ORTHOLOGY: K17450
Entry
K17450                      KO                                     
Symbol
ACO2
Name
homoaconitase [EC:4.2.1.-]
Pathway
map00300  Lysine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
map01120  Microbial metabolism in diverse environments
map01210  2-Oxocarboxylic acid metabolism
map01230  Biosynthesis of amino acids
Module
M00030  Lysine biosynthesis, AAA pathway, 2-oxoglutarate => 2-aminoadipate => lysine
M00433  Lysine biosynthesis, 2-oxoglutarate => 2-oxoadipate
Reaction
R03444  (R)-2-hydroxybutane-1,2,4-tricarboxylate hydro-lyase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09105 Amino acid metabolism
   00300 Lysine biosynthesis
    K17450  ACO2; homoaconitase
Enzymes of 2-oxocarboxylic acid metabolism [br01601.html]
 2-Oxoacid chain elongation
  K17450
Other DBs
COG: COG1048
Genes
SCE: YJL200C(ACO2)
SEUB: DI49_2832
SPAO: SPAR_J00200
AGO: AGOS_AFR629W
ERC: Ecym_8142
KLA: KLLA0_C03432g
KMX: KLMA_10153(ACO2a)
LTH: KLTH0F03586g
VPO: Kpol_2001p56
ZRO: ZYRO0C17974g
CGR: 2887762(ACO2)
NCS: NCAS_0F00160(NCAS0F00160)
NDI: NDAI_0K02930(NDAI0K02930)
TPF: TPHA_0D04460(TPHA0D04460)
TBL: TBLA_0J00580(TBLA0J00580)
TDL: TDEL_0C05660(TDEL0C05660)
KAF: KAFR_0F01540(KAFR0F01540)
KNG: KNAG_0C02160(KNAG0C02160)
PIC: PICST_90724(ACO2)
SPAA: SPAPADRAFT_133954(ACO2)
LEL: PVL30_002661(ACO2)
LBG: 92206901(LODBEIA_P17050)
CAL: CAALFM_CR05790CA(ACO2)
CTEN: 18245525(ACO2)
BNN: FOA43_002978(ACO2)
BBRX: BRETT_001582(ACO2)
YLI: 2911538(YALI2_E00299g)
SLB: AWJ20_2939(ACO2)
NCR: NCU04280
NTE: NEUTE1DRAFT75176(NEUTE1DRAFT_75176)
PBEL: QC761_212390(ACO2)
PPSD: QC762_212390(ACO2)
PPSP: QC763_212390(ACO2)
PPSA: QC764_212390(ACO2)
MGR: MGG_08584
PGRI: PgNI_00226
SSCK: SPSK_08585
TATV: 25776110(TrAtP1_003292)
TASP: 90966786(TrAFT101_006980)
MAW: 90962543(ACO2_1)
MAJ: MAA_02899
MBRN: 26241620(G6M90_00g075090)
CMT: CCM_01579
PLJ: 28890803(PLICBS_004865)
PTKZ: JDV02_006694(ACO2_1)
CDET: 87950312(CDEST_13812)
BFU: BCIN_04g04360(Bcaco2)
MBE: MBM_04948
ALUC: AKAW2_40427S(ACO2)
ACHE: ACHE_11140A(ACO2)
APUU: APUU_40479A(ACO2)
ABE: ARB_00016
TVE: TRV_07808
PTE: PTT_12730
PTRR: 6342643(PtrM4_088320)
ZTR: MYCGRDRAFT_88201(ACO2)
CNE: CNM01770
CNB: CNBM1650
CDEU: CNBG_4882
CDEP: 91090075(L203_105866)
KMG: 30165514(I203_100429)
KNE: 92181913(IAR55_004655)
TASA: A1Q1_04528
CCAC: CcaHIS019_0200960(ACO2)
ABP: AGABI1DRAFT66587(AGABI1DRAFT_66587)
ABV: AGABI2DRAFT62721(AGABI2DRAFT_62721)
MRR: Moror_157
SCM: SCHCO_02697228(SCHCODRAFT_02697228)
MGL: MGL_0395
MRT: MRET_2215
 » show all
Reference
  Authors
Fazius F, Shelest E, Gebhardt P, Brock M
  Title
The fungal alpha-aminoadipate pathway for lysine biosynthesis requires two enzymes of the aconitase family for the isomerization of homocitrate to homoisocitrate.
  Journal
Mol Microbiol 86:1508-30 (2012)
DOI:10.1111/mmi.12076
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