KEGG ORTHOLOGY: K17548

ORTHOLOGY: K17548

Entry

K17548                      KO

Symbol

PKDCC

Name

extracellular tyrosine-protein kinase PKDCC [EC:2.7.10.2]

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01001 Protein kinases
    K17548  PKDCC; extracellular tyrosine-protein kinase PKDCC
Enzymes [BR:ko01000]
2. Transferases
  2.7  Transferring phosphorus-containing groups
   2.7.10  Protein-tyrosine kinases
    2.7.10.2  non-specific protein-tyrosine kinase
     K17548  PKDCC; extracellular tyrosine-protein kinase PKDCC
Protein kinases [BR:ko01001]
Non-receptor tyrosine kinases
  Other
   K17548  PKDCC; extracellular tyrosine-protein kinase PKDCC

Genes

HSA:	91461(PKDCC)

PTR:	736991(PKDCC)

PPS:	100970019(PKDCC)

GGO:	101147287(PKDCC)

PON:	100454756(PKDCC)

NLE:	100595482(PKDCC)

HMH:	116483478(PKDCC)

MCC:	714824(PKDCC)

MCF:	102125389(PKDCC)

MTHB:

126933500

MNI:	105464911(PKDCC)

CSAB:

103220408(PKDCC)

CATY:

105597102(PKDCC)

PANU:

101002170(PKDCC)

TGE:	112605162(PKDCC)

MLEU:

105538343(PKDCC)

RRO:	104677546(PKDCC)

RBB:	108513227(PKDCC)

TFN:	117062415(PKDCC)

PTEH:

111524193(PKDCC)

CANG:

105507434(PKDCC)

CJC:	100411473(PKDCC)

SBQ:	101034404(PKDCC)

CIMI:

108315518(PKDCC)

CSYR:

103253883(PKDCC)

MMUR:

105866997(PKDCC)

LCAT:

123636838(PKDCC)

PCOQ:

105818013(PKDCC)

OGA:	100961098(PKDCC)

MMU:	106522(Pkdcc)

MCAL:

110312651(Pkdcc)

MPAH:

110335656(Pkdcc)

RNO:	313860(Pkdcc)

MCOC:

116080285(Pkdcc)

ANU:	117717256(Pkdcc)

MUN:	110555470(Pkdcc)

CGE:	100764428(Pkdcc)

MAUA:

101826280(Pkdcc)

PROB:

127214892(Pkdcc)

PLEU:

114708895(Pkdcc)

MORG:

121433107(Pkdcc)

MFOT:

126504068

AAMP:

119807920(Pkdcc)

NGI:	103736384(Pkdcc)

HGL:	101715304(Pkdcc)

CPOC:

100723658(Pkdcc)

CCAN:

109701539(Pkdcc)

DORD:

105986800(Pkdcc)

DSP:	122104572(Pkdcc)

PLOP:

125356517(Pkdcc)

NCAR:

124963153

MMMA:

107137330(Pkdcc)

OCU:

100353337

OPI:	101533629(PKDCC)

TUP:	102502866(PKDCC)

GVR:	103587995(PKDCC)

CFA:	611604(PKDCC)

CLUD:

112664462(PKDCC)

VVP:	112916844(PKDCC)

VLG:	121491108(PKDCC)

NPO:	129511052(PKDCC)

AML:	100475756(PKDCC)

UMR:	103671885(PKDCC)

UAH:	113241774(PKDCC)

UAR:	123799798(PKDCC)

ELK:

111158418

LLV:

125109024

MPUF:

101692881(PKDCC)

MNP:	132021321(PKDCC)

MLK:	131840485(PKDCC)

NVS:	122915127(PKDCC)

ORO:	101369726(PKDCC)

EJU:	114219638(PKDCC)

ZCA:	113938539(PKDCC)

MLX:	118007810(PKDCC)

NSU:	110587328(PKDCC)

LWW:	102727792(PKDCC)

FCA:	101094841(PKDCC)

PYU:	121044526(PKDCC)

PCOO:

112864135(PKDCC)

PBG:	122497230(PKDCC)

PVIV:

125162849(PKDCC)

LRUF:

124504403

PTG:	102971985(PKDCC)

PPAD:

109265344(PKDCC)

PUC:

125937506

AJU:

106986296

HHV:	120231608(PKDCC)

BTA:	539467(PKDCC)

BOM:	102287263(PKDCC)

BIU:	109566014(PKDCC)

BBUB:

102415156(PKDCC)

BBIS:

104990321(PKDCC)

CHX:	102177986(PKDCC)

OAS:	101116218(PKDCC)

BTAX:

128055509(PKDCC)

ODA:	120851634(PKDCC)

CCAD:

122441607(PKDCC)

MBEZ:

129539633(PKDCC)

SSC:	100516968(PKDCC)

CFR:	102507594(PKDCC)

CBAI:

105078996(PKDCC)

CDK:	105103543(PKDCC)

VPC:	102540094(PKDCC)

BACU:

103010710(PKDCC)

BMUS:

118906372(PKDCC)

LVE:	103073891(PKDCC)

OOR:	101283799(PKDCC)

DLE:	111174839(PKDCC)

PCAD:

102986736(PKDCC)

PSIU:

116764523(PKDCC)

NASI:

112405169(PKDCC)

ECB:	100069409(PKDCC)

EPZ:	103543022(PKDCC)

EAI:	106848304(PKDCC)

MYB:	102254675(PKDCC)

MYD:	102759448(PKDCC)

MMYO:

118669066(PKDCC)

MLF:	102441063(PKDCC)

PKL:	118717280(PKDCC)

EFUS:

103305442(PKDCC)

MNA:	107539755(PKDCC)

DRO:	112298161(PKDCC)

SHON:

119001305(PKDCC)

AJM:	119061533(PKDCC)

PDIC:

114500480(PKDCC)

PHAS:

123811675(PKDCC)

MMF:	118630834(PKDCC)

PPAM:

129065928(PKDCC)

HAI:	109385558(PKDCC)

RFQ:	117033260(PKDCC)

PALE:

102880499(PKDCC)

PGIG:

120621728(PKDCC)

PVP:	105292980(PKDCC)

RAY:	107509445(PKDCC)

MJV:	108407924(PKDCC)

TOD:	119259368(PKDCC)

SARA:

101537854(PKDCC)

SETR:

126023872(PKDCC)

LAV:	100669593(PKDCC)

TMU:

101356083

ETF:	101651850(PKDCC)

DNM:	101422615(PKDCC)

MDO:	100033383(PKDCC)

GAS:	123233318(PKDCC)

SHR:	100929886(PKDCC)

AFZ:

127548018

PCW:	110218518(PKDCC)

OAA:	100074321(PKDCC) 100082037

GGA:	421390(PKDCCA) 423451(PKDCCB)

PCOC:

116228775 116230130(PKDCC)

MGP:	100542674(PKDCC) 100546859

CJO:	107311115(PKDCC) 107315363

TPAI:

128085656 128089215(PKDCC)

LMUT:

125689052(PKDCC) 125694746

NMEL:

110395727(PKDCC) 110401851

APLA:

101792124 101796743(PKDCC)

ACYG:

106031614(PKDCC) 106036078

CATA:

118254660(PKDCC) 118258187

AFUL:

116487943(PKDCC) 116489476

TGU:	100219136 100220021(PKDCC)

LSR:	110479946(PKDCC) 110481185

SCAN:

103817008(PKDCC) 103826879

PMOA:

120497006(PKDCC) 120503879

OTC:	121340697(PKDCC) 121343210

PRUF:

121358196 121358768(PKDCC)

GFR:	102034608(PKDCC) 102044504

FAB:	101808331(PKDCC) 101816451

OMA:	130251595(PKDCC) 130253790

PHI:	102102372(PKDCC) 102111069

PMAJ:

107201245(PKDCC) 107205380

CCAE:

111926151(PKDCC) 111929542

CCW:	104685666(PKDCC) 104688779

CBRC:

103612233 103622744(PKDCC)

ETL:	114061695 114062257(PKDCC)

ZAB:	102073348(PKDCC) 102075230

ACHL:

103801109 103802516

SVG:	106850576 106859868(PKDCC)

MMEA:

130574445(PKDCC) 130580253

HRT:	120751164(PKDCC) 120754149

FPG:	101918495 101919425(PKDCC)

FCH:	102048315 102059909

CLV:	102089274(PKDCC) 110361406

EGZ:	104124528 104128727(PKDCC)

NNI:	104014835 104019721(PKDCC)

PCRI:

104027860 104032897(PKDCC)

PLET:

104614872

EHS:	104508077 104516235

PCAO:

104046550 104053114(PKDCC)

ACUN:

113477622(PKDCC) 113480899

TALA:

104356162 104360890(PKDCC)

PADL:

103920692 103922117(PKDCC)

AFOR:

103899209(PKDCC) 103900314

ACHC:

115338402 115350181(PKDCC)

HALD:

104311223

HLE:	104837420(PKDCC) 104841976

AGEN:

126050710 126052769

GCL:	127014752 127017028

CCRI:

104168910 104169425(PKDCC)

CSTI:

104559564(PKDCC) 104559649

CMAC:

104480144

MUI:	104535663(PKDCC)

BREG:

104639494

FGA:

104070723

GSTE:

104251737 104256501(PKDCC)

LDI:	104343428(PKDCC) 104346118

MNB:	103770441 103771832(PKDCC)

OHA:	104327923(PKDCC) 104331567

NNT:	104401833(PKDCC) 104411856

SHAB:

115606188 115613827(PKDCC)

DPUB:

104296749(PKDCC) 104304676

PGUU:

104459174

ACAR:

104525514 104530495

CPEA:

104389077 104395284(PKDCC)

AVIT:

104273740(PKDCC) 104278690

CVF:	104289658(PKDCC) 104291790

RTD:	128907570(PKDCC) 128908627

CUCA:

104057793 104058047(PKDCC)

TEO:	104374339(PKDCC) 104377809

BRHI:

104495910(PKDCC) 104496143

AAM:	106490337(PKDCC)

AROW:

112969198(PKDCC) 112972641

NPD:	112953262(PKDCC) 112956947

TGT:

104568992

DNE:	112989915 112997325(PKDCC)

SCAM:

104140270(PKDCC) 104144518

ASN:	102369832(PKDCC) 102376569

AMJ:	102571715 106737107(PKDCC)

CPOO:

109319056(PKDCC) 109320870

GGN:	109296485(PKDCC) 109299305

PSS:	102444014(PKDCC) 112545926

CMY:	102940765 102948116(PKDCC)

CCAY:

125633580(PKDCC) 125639049

DCC:	119853971(PKDCC) 119856613

CPIC:

101937514 101945582(PKDCC)

TST:	117874403(PKDCC) 117877270

CABI:

116816346(PKDCC)

MRV:	120402251(PKDCC)

ACS:	100552212 100553953

ASAO:

132761470(PKDCC) 132762536

PVT:	110084392(PKDCC) 110090554

SUND:

121919236 121935434(PKDCC)

PBI:	103060463 103064360(PKDCC)

PMUR:

107286419(PKDCC) 107291266

CTIG:

120306445 120309952(PKDCC)

TSR:	106546935(PKDCC) 106556789

PGUT:

117665977 117671652(PKDCC)

APRI:

131187908 131189241(PKDCC)

PTEX:

113433310(PKDCC) 113434995

NSS:	113420223(PKDCC) 113420359

VKO:	123022957(PKDCC) 123026344

PMUA:

114588283 114594720(PKDCC)

PRAF:

128407191 128411192(PKDCC)

ZVI:	118075202 118083131(PKDCC)

HCG:	128339648 128351555(PKDCC)

GJA:	107108202(PKDCC) 107121535

STOW:

125425714 125437086(PKDCC)

EMC:	129324404 129330720(PKDCC)

XLA:	100037022(pkdcc.1.S) 108698774(pkdcc.1.L) 108716435(pkdcc.2.L) 108717726(pkdcc.2.S)

XTR:	100145744(pkdcc.2) 100216132(pkdcc.1)

NPR:	108784590(PKDCC) 108790746

RTEM:

120920383 120937946(PKDCC)

BBUF:

120982494 120999458(PKDCC)

BGAR:

122922208 122934491(PKDCC)

MUO:	115464218(PKDCC) 115478131

GSH:	117356447(PKDCC) 117363958

DRE:	559418(pkdcca) 565254(pkdccb)

SRX:	107718010 107719463 107733116 107739483

SANH:

107669579 107674029 107695038 107697741

SGH:	107563378 107586469 107590011 107594843

CCAR:

109078394 109080102

CAUA:

113057240 113060595 113069075 113113044 113117477

CGIB:

127933466 127970764 127975979 128026478

PTET:

122356915(pkdcca) 122362091(pkdccb)

LROH:

127175620(pkdcca) 127179979(pkdccb)

OMC:	131523304(pkdccb) 131552316(pkdcca)

PPRM:

120477240(pkdccb) 120492345(pkdcca)

RKG:	130095203(pkdcca) 130100788(pkdccb)

MAMB:

125268916(pkdccb) 125277469(pkdcca)

CIDE:

127499129 127525435

MASI:

127410889 127412174 127413702 127455122

TROS:

130559729(pkdcca) 130560523(pkdccb)

TDW:	130431280(pkdcca) 130436548(pkdccb)

MANU:

129416483(pkdcca) 129417642(pkdccb)

IPU:	108263834(pkdcca) 108270133(pkdccb)

IFU:	128605395(pkdcca) 128613172(pkdccb)

PHYP:

113538857 113538971(pkdcc)

SMEO:

124390217(pkdccb) 124401595(pkdcca)

TFD:	113645057(pkdcca) 113659386(pkdccb)

TVC:	132847116(pkdcca) 132852217(pkdccb)

AMEX:

103032971(pkdcc) 103046407

CMAO:

118810205(pkdcca) 118824160(pkdccb)

EEE:	113572768(pkdcc) 113576657

CHAR:

105899575(pkdccb) 105900045(pkdcca)

TRU:	101079806(pkdcc)

TFS:	130540306(pkdccb)

LCO:	104921567(pkdcc)

NCC:	104960355(pkdcc)

TBEN:

117477543(pkdccb)

CGOB:

115026989(pkdcc)

PGEO:

117468128(pkdccb)

GACU:

117550079(pkdccb)

EMAC:

134881237(pkdccb)

ELY:	117266605(pkdccb)

EFO:	125900626(pkdccb)

PLEP:

121953584(pkdccb)

SLUC:

116035828(pkdccb)

ECRA:

117936047(pkdccb)

ESP:	116669588(pkdcc)

PFLV:

114547362(pkdcc)

GAT:	120833244(pkdccb)

PPUG:

119228173(pkdccb)

AFB:	129103623(pkdccb)

CLUM:

117725113(pkdccb)

PSWI:

130201434(pkdccb)

MSAM:

119910628(pkdccb)

SCHU:

122861512(pkdccb)

CUD:	121526681(pkdccb)

ALAT:

119005227(pkdccb)

MZE:	101478809(pkdcc)

ONL:	100692556(pkdcc)

OAU:	116334844(pkdccb)

OLA:	101157987(pkdcc)

OML:	112150330(pkdccb)

CSAI:

133462602(pkdccb)

XMA:	111612302(pkdcc)

XCO:	114134549(pkdcc)

XHE:	116709431(pkdcc)

PRET:

103458888(pkdcc)

PFOR:

103144258(pkdcc)

PLAI:

106954638(pkdcc)

PMEI:

106918263(pkdcc)

GAF:	122846511(pkdccb)

PPRL:

129374871(pkdccb)

CVG:	107087579(pkdcc)

CTUL:

119784274(pkdccb)

GMU:	124855588(pkdccb)

NFU:	107392294(pkdcc)

KMR:	108232268(pkdccb)

ALIM:

106521504(pkdcc)

NWH:	119427333(pkdccb)

AOCE:

111588538(pkdcc)

MCEP:

125024101(pkdccb)

CSEM:

103377380(pkdcc)

POV:	109628225(pkdcc)

SSEN:

122782421(pkdccb)

HHIP:

117756360(pkdccb)

HSP:	118116252(pkdccb)

SMAU:

118285961(pkdccb)

LCF:	108888116(pkdccb)

SDU:	111225738(pkdcc)

SLAL:

111644798(pkdcc)

XGL:	120795131(pkdccb)

HCQ:	109526160(pkdcc)

SSCV:

125980401

SBIA:

133513678(pkdccb)

PEE:	133412697(pkdccb)

PTAO:

133488137(pkdccb)

BPEC:

110155495(pkdcc)

MALB:

109955248(pkdcc)

BSPL:

114849001(pkdccb)

SJO:	128375428(pkdccb)

SASA:

106576746 106605748(pkdcc) 106608828 106610624

STRU:

115153089 115162642 115193915

OTW:	112252878(pkdcca) 112253234 112257110(pkdccb)

OMY:	110502346 110505214(pkdccb) 110527203(pkdcca)

OGO:	124038170 124041365(pkdcca) 124046218

ONE:	115113320 115135235 115138918

OKI:	109889836 109899081(pkdcc) 109903138

OKE:	118369288(pkdccb) 118369581(pkdcca) 118401238

SALP:

111978346 112068215 112080506

SNH:	120017570(pkdcca) 120023375 120045607 120059744

CCLU:

121539708 121544437 121553485 121569432

ELS:	105008312(pkdcc) 105015972

SFM:	108941460 108942756(pkdcc)

PKI:	111848832(pkdcc) 111852374

AANG:

118212162(pkdccb) 118217561(pkdcca)

LOC:	102692235(pkdcc) 102697009

PSPA:

121316366(pkdcca) 121316667 121324268 121330274

ARUT:

117403010 117410697 117422692 117971250 117971252 117971688 117971691 117973885

PSEX:

120516585(pkdcca) 120518639(pkdccb)

LCM:	102359232(PKDCC) 102362376

CMK:	103175384 103178031(pkdcca)

RTP:	109921835 109922215(pkdcca)

CPLA:

122552781(pkdcca) 122553968

HOC:	132817943 132819727(pkdcca)

LERI:

129699683(pkdcca)

PMRN:

116943269(PKDCC)

LRJ:

133342184

BFO:	118405572 118407352 118417238

BBEL:

109470428 109472320 109484438

CIN:

100184284

SCLV:

120325659

SPU:	578081 583754

LPIC:

129265737

APLC:

110984852 110987292

SKO:	100374906 102806241

NLU:

HVI:

MQU:

ZNE:

CSEC:

BROR:

IEL:	124156849 124156889 124156898 124156904 124157798 124157800 124158289

DPX:	DAPPUDRAFT_107401

DMK:

PVM:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

CQD:

PTRU:

ESN:

MNZ:

PPOI:

CSCU:

PTEP:

ABRU:

UDV:

SDM:

TSP:

HRO:	HELRODRAFT_193594

LGI:	LOTGIDRAFT_158812 LOTGIDRAFT_62659

PVUL:

126821428

PCAN:

112555190 112570739

BGT:	106052000 106055711 106075241

GAE:	121367655 121367679 121371643

HRF:	124120165 124129874

HRJ:	124271956 124291892

CRG:	105338496 105338695 105344409

CVN:	111112400 111128878

CANU:

128176061 128181108 128181260

OED:	125650666 125659174

MYI:	110442668 110460932 110465292

PMAX:

117324533 117333275 117341652

MMER:

123535240 123543758 123543788 123543810 123555250 123555377

RPHI:

132760188

DPOL:

127870819

OBI:

106882243

OSN:	115230083 115232032

LAK:	106169624 106172210

NVE:

5506154

EPA:	110242739 110242742

ATEN:

AMIL:

SPIS:

DGT:

XEN:

Reference

PMID:19465597

Authors

Kinoshita M, Era T, Jakt LM, Nishikawa S

Title

The novel protein kinase Vlk is essential for stromal function of mesenchymal cells.

Journal

Development 136:2069-79 (2009)
DOI:10.1242/dev.026435

Sequence

[hsa:91461]

Reference

PMID:25171405

Authors

Bordoli MR, Yum J, Breitkopf SB, Thon JN, Italiano JE Jr, Xiao J, Worby C, Wong SK, Lin G, Edenius M, Keller TL, Asara JM, Dixon JE, Yeo CY, Whitman M

Title

A secreted tyrosine kinase acts in the extracellular environment.

Journal

Cell 158:1033-1044 (2014)
DOI:10.1016/j.cell.2014.06.048

Sequence

[hsa:91461]

LinkDB

DBGET integrated database retrieval system