KEGG ORTHOLOGY: K17558

ORTHOLOGY: K17558

Entry

K17558                      KO

Symbol

PPP1R15B, CREP

Name

protein phosphatase 1 regulatory subunit 15B

Disease

H01923

Microcephaly, short stature, and impaired glucose metabolism

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K17558  PPP1R15B, CREP; protein phosphatase 1 regulatory subunit 15B
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K17558  PPP1R15B, CREP; protein phosphatase 1 regulatory subunit 15B

Genes

HSA:	84919(PPP1R15B)

PTR:	742092(PPP1R15B)

PPS:	100982466(PPP1R15B)

GGO:	101133105(PPP1R15B)

PON:	100462037(PPP1R15B)

PPYG:

129007892(PPP1R15B)

NLE:	100593814(PPP1R15B)

HMH:	116457745(PPP1R15B)

SSYN:

129458430(PPP1R15B)

MCC:	699809(PPP1R15B)

MCF:	101866886(PPP1R15B)

MTHB:

126938815

MNI:	105484796(PPP1R15B)

CSAB:

103230250(PPP1R15B)

CATY:

105576184(PPP1R15B)

PANU:

101015764(PPP1R15B)

TGE:	112619007(PPP1R15B)

MLEU:

105547055(PPP1R15B)

RRO:	104667390(PPP1R15B)

RBB:	108535189(PPP1R15B)

TFN:	117075304(PPP1R15B)

PTEH:

111522779(PPP1R15B)

CANG:

105504416(PPP1R15B)

CJC:	100400726(PPP1R15B)

SBQ:	101034467(PPP1R15B)

CIMI:

108302035(PPP1R15B)

ANAN:

105722142(PPP1R15B)

CSYR:

103269094(PPP1R15B)

MMUR:

105868384(PPP1R15B)

LCAT:

123626847(PPP1R15B)

PCOQ:

105821216(PPP1R15B)

OGA:	100951460(PPP1R15B)

MMU:	108954(Ppp1r15b)

MCAL:

110302241(Ppp1r15b)

MPAH:

110321777(Ppp1r15b)

RNO:	304799(Ppp1r15b)

MCOC:

116099237(Ppp1r15b)

ANU:	117716147(Ppp1r15b)

ASYL:

127697230(Ppp1r15b)

MUN:	110546753(Ppp1r15b)

CGE:	100766520(Ppp1r15b)

MAUA:

101826365(Ppp1r15b)

PROB:

127236332(Ppp1r15b)

PLEU:

114692284 114698089(Ppp1r15b)

MORG:

121446372(Ppp1r15b)

MFOT:

126505009

AAMP:

119827702(Ppp1r15b)

NGI:	103731877(Ppp1r15b)

HGL:	101722274(Ppp1r15b)

CPOC:

100722836(Ppp1r15b)

CCAN:

109699776(Ppp1r15b)

DORD:

105986427(Ppp1r15b)

DSP:	122109371(Ppp1r15b)

DMER:

138841144(Ppp1r15b)

PLOP:

125359417(Ppp1r15b)

NCAR:

124962134

MMMA:

107140712(Ppp1r15b)

ITI:	101960688(Ppp1r15b)

OCU:

100357764

OPI:	101531311(PPP1R15B)

OCZ:	121159971(PPP1R15B)

TUP:	102493733(PPP1R15B)

GVR:	103594172(PPP1R15B)

CFA:	488563(PPP1R15B)

CLUD:

112643242(PPP1R15B)

VVP:	112914395(PPP1R15B)

VLG:	121471806(PPP1R15B)

NPO:	129515356(PPP1R15B)

AML:	100465583(PPP1R15B)

UMR:	103670974(PPP1R15B)

UAH:	113242504(PPP1R15B)

UAR:	123785700(PPP1R15B)

ELK:

111151117

LLV:

125085905

MPUF:

101671933(PPP1R15B)

MNP:	132025643(PPP1R15B)

MLK:	131814589(PPP1R15B)

NVS:	122918823(PPP1R15B)

ORO:	101381698(PPP1R15B)

EJU:	114221917(PPP1R15B)

ZCA:	113932498(PPP1R15B)

MLX:	118014161(PPP1R15B)

NSU:	110577277(PPP1R15B)

LWW:	102734542(PPP1R15B)

FCA:	101083996(PPP1R15B)

PYU:	121021693(PPP1R15B)

PCOO:

112857850(PPP1R15B)

PBG:	122476350(PPP1R15B)

PVIV:

125155822(PPP1R15B)

LRUF:

124509991

LGF:	123586832(PPP1R15B)

AJU:

106972874

PTG:	102955919(PPP1R15B)

PPAD:

109257019(PPP1R15B)

PUC:

125925450

PLEZ:

122211593(PPP1R15B)

HHV:	120228875(PPP1R15B)

BTA:	538754(PPP1R15B)

BOM:	102270877(PPP1R15B)

BIU:	109570347(PPP1R15B)

BBUB:

102416361(PPP1R15B)

BBIS:

104998795(PPP1R15B)

CHX:	102180245(PPP1R15B)

OAS:	101108505(PPP1R15B)

BTAX:

128061196(PPP1R15B)

CSUM:

138090472(PPP1R15B)

ODA:	120879977(PPP1R15B)

CCAD:

122451785(PPP1R15B)

MREE:

136169933(PPP1R15B)

MBEZ:

129551773(PPP1R15B)

SSC:	100512360(PPP1R15B)

CFR:	102510686(PPP1R15B)

CBAI:

105077067(PPP1R15B)

CDK:	105098646(PPP1R15B)

VPC:	102530840(PPP1R15B)

BACU:

103013569(PPP1R15B)

BMUS:

118899174(PPP1R15B)

LVE:	103069907(PPP1R15B)

OOR:	101282860(PPP1R15B)

LALB:

132508820(PPP1R15B)

GMF:	115861729(PPP1R15B)

DDP:	132413904(PPP1R15B)

DLE:	111184787(PPP1R15B)

PCAD:

102996578(PPP1R15B)

PSIU:

116759033(PPP1R15B)

PPHC:

136135160(PPP1R15B)

NASI:

112403497(PPP1R15B)

ECB:	106783133(PPP1R15B)

MYB:	102240722(PPP1R15B)

MMYO:

118672856(PPP1R15B)

MLF:	102418163(PPP1R15B)

MDT:	132220714(PPP1R15B)

MYUM:

138996390(PPP1R15B)

PKL:	118721468(PPP1R15B)

EFUS:

103297565(PPP1R15B)

MNA:	107538652(PPP1R15B)

DRO:	112317956(PPP1R15B)

SHON:

119001641(PPP1R15B)

AJM:	119056816(PPP1R15B)

PDIC:

114511848(PPP1R15B)

PHAS:

123820605(PPP1R15B)

MMF:	118637423(PPP1R15B)

PPAM:

129062410(PPP1R15B)

HAI:	109386515(PPP1R15B)

RFQ:	117014418(PPP1R15B) 117024653

PALE:

102891012(PPP1R15B)

PGIG:

120617973(PPP1R15B)

PVP:	105300679(PPP1R15B)

RAY:	107508376(PPP1R15B)

MJV:	108408666(PPP1R15B)

TOD:	119233852(PPP1R15B)

SFUM:

130028313(PPP1R15B)

SETR:

126004346(PPP1R15B)

LAV:	100657923(PPP1R15B)

TMU:

101353906

DNM:	101434865(PPP1R15B)

MDO:	100017447(PPP1R15B)

GAS:	123247003(PPP1R15B)

SHR:	105750318(PPP1R15B)

AFZ:

127562670

PCW:	110219606(PPP1R15B)

TVP:	118829721 118846427(PPP1R15B)

PBRV:

138151133(PPP1R15B)

OAA:	100075338(PPP1R15B)

TACU:

119930442(PPP1R15B)

GGA:	100857158(PPP1R15B)

PCOC:

116237060(PPP1R15B)

MGP:	104914516(PPP1R15B)

CJO:	107324702(PPP1R15B)

TPAI:

128088107(PPP1R15B)

LMUT:

125684216(PPP1R15B)

NMEL:

110388178(PPP1R15B)

APLA:

101797177(PPP1R15B)

ACYG:

106041284(PPP1R15B)

CATA:

118255317(PPP1R15B)

AFUL:

116498680(PPP1R15B)

TGU:	100221684(PPP1R15B)

LSR:	110474990(PPP1R15B)

SCAN:

103824507(PPP1R15B)

PMOA:

120499096(PPP1R15B)

OTC:	121345570(PPP1R15B)

PRUF:

121355239(PPP1R15B)

ATRC:

139601200(PPP1R15B)

GFR:	102031918(PPP1R15B)

FAB:	101813509(PPP1R15B)

PHI:	102103931(PPP1R15B)

PMAJ:

107215008(PPP1R15B)

CCAE:

111939890(PPP1R15B)

CCW:	104692343(PPP1R15B)

ACOE:

138098809(PPP1R15B)

ETL:	114069116(PPP1R15B)

ZAB:	102067051(PPP1R15B)

ZLE:	135458194(PPP1R15B)

SVG:	106850914(PPP1R15B)

MMEA:

130586901

HRT:	120762981(PPP1R15B) 120762983

SATI:

136371652(PPP1R15B)

CCIC:

134054066(PPP1R15B)

FPG:	101917333(PPP1R15B)

FCH:	102049902(PPP1R15B)

CCRI:

104166136(PPP1R15B)

SHAB:

115602286(PPP1R15B)

TALA:

104366038(PPP1R15B)

ACHC:

115335292(PPP1R15B)

HLE:	104839595(PPP1R15B)

AGEN:

126052166

HHAR:

128154247(PPP1R15B)

GCL:

127026156

LDI:	104344938(PPP1R15B)

MNB:

103771178

DPUB:

104305408(PPP1R15B)

PPUS:

135191398(PPP1R15B)

AVIT:

104273542

BRHI:

104502374

EGZ:	104125795(PPP1R15B)

NNI:	104013206(PPP1R15B)

PCRI:

104034015(PPP1R15B)

PADL:

103919856(PPP1R15B)

AFOR:

103893696(PPP1R15B)

CBOR:

142093308(PPP1R15B)

CBOY:

140662725(PPP1R15B)

MAME:

142419232(PPP1R15B)

CLV:	102093405(PPP1R15B)

CNIC:

135997116(PPP1R15B)

MUI:	104541964(PPP1R15B)

PGUU:

104465900

PLET:

104622127(PPP1R15B)

CMAC:

104485449

BREG:

104632386

CVF:	104289355(PPP1R15B)

RTD:	128900327(PPP1R15B)

CRID:

134525583(PPP1R15B)

LMIC:

141733639(PPP1R15B)

AAM:	106484862(PPP1R15B)

AROW:

112971599(PPP1R15B)

NPD:	112959126(PPP1R15B)

TGT:

104575926

DNE:	112990352(PPP1R15B)

ASN:	102386926(PPP1R15B)

AMJ:	102564193(PPP1R15B)

CPOO:

109317750(PPP1R15B) 109320807(PPP1R15A)

GGN:	109295085(PPP1R15B)

PSS:	102463029(PPP1R15B)

CIZ:	142001933(PPP1R15B)

CMY:	102945567(PPP1R15B)

CCAY:

125624950(PPP1R15B)

DCC:	119846380(PPP1R15B)

CPIC:

101931064(PPP1R15B)

TST:	117875807(PPP1R15B) 117888426(PPP1R15A)

CABI:

116827912(PPP1R15B) 116840047(PPP1R15A)

MRV:	120388283(PPP1R15A) 120404907(PPP1R15B)

ACS:	100557362(ppp1r15b)

ASAO:

132773642(PPP1R15B)

PVT:	110080861(PPP1R15B)

SUND:

121928154(PPP1R15B) 121933479(PPP1R15A)

PBI:	103054808(PPP1R15B)

PMUR:

107302980(PPP1R15B)

CTIG:

120306874(PPP1R15B)

TSR:	106557117(PPP1R15B)

PGUT:

117663907(PPP1R15B) 117669102(PPP1R15A) 132710593

PCAE:

139315340(PPP1R15B)

PTEX:

113446091(PPP1R15B)

NSS:	113418129(PPP1R15B)

VKO:	123031109(PPP1R15B) 123032118(PPP1R15A)

PMUA:

114599290(PPP1R15B)

PRAF:

128416095(PPP1R15B)

ZVI:	118088149(PPP1R15B)

HCG:	128324851(PPP1R15B)

GJA:	107107096(PPP1R15B)

STOW:

125433214(PPP1R15B) 125444279(PPP1R15A)

EMC:	129329718(PPP1R15B)

XLA:	108695908 108697799 495456(ppp1r15b-b) 495701(ppp1r15b.L)

XTR:	100380185(ppp1r15b) 100489802

NPR:

108800248

RTEM:

120915343 120927125(PPP1R15B)

ACAT:

141110981 141128510(PPP1R15B)

PADS:

140341540

BBUF:

120995039(PPP1R15B) 121001932

BGAR:

122928640 122933425(PPP1R15B)

DTC:	141085495 141085502(PPP1R15A) 141099089(PPP1R15B)

PWL:	138246333(PPP1R15A) 138299857(PPP1R15B)

MUO:	115466575 115481703(PPP1R15B)

GSH:	117347440(PPP1R15B) 117368504

DRE:	100538163(ppp1r15b) 571470

SRX:	107715199 107725730 107727191 107727760

SANH:

107655998 107660754 107690400 107691156

SGH:	107557518 107562114 107567888 107602990

CCAR:

109064528 109073468 122140410 122146601 122148534

CAUA:

113055214 113061641 113111207 113118490

CGIB:

127933867 127968447 127977207 128022355

PTET:

122323073(ppp1r15b) 122354025

LROH:

127173153 127180764(ppp1r15b)

GRF:	141293645(ppp1r15b)

OMC:	131524918(ppp1r15b) 131549723

PPRM:

120487598(ppp1r15b) 120495281

RKG:	130087497(ppp1r15b) 130103568

MAMB:

125254534(ppp1r15b) 125256874

CIDE:

127499547 127522925

CERY:

137021566 137022955(ppp1r15b)

MASI:

127416816 127425812

TROS:

130562956(ppp1r15b) 130571566

TDW:	130410590 130435433(ppp1r15b)

MANU:

129418656 129427488(ppp1r15b)

PDAB:

135718954(ppp1r15b) 135773491

IPU:	108254899 108263894(ppp1r15b)

IFU:	128606796(ppp1r15b) 128625168

PHYP:

113539585(ppp1r15b) 113539722 113539808

SMEO:

124395721(ppp1r15b) 124402409

TFD:	113641532 113652267(ppp1r15b)

TVC:	132837781 132851092(ppp1r15b)

CGAR:

128511327 128528041(ppp1r15b)

NGRA:

132874677 132888315(ppp1r15b)

TRN:	134301814 134323553(ppp1r15b)

AMEX:

103038944(ppp1r15b) 103042795

CMAO:

118799380 118801403(ppp1r15b)

EEE:	113576617 113589086

CHAR:

105895911 105905544(ppp1r15b)

SPIL:

134093050 134093833(ppp1r15b)

ASAD:

121707940 121723372(ppp1r15b)

TRU:	101063094 101065523

TFS:	130523959 130536249(ppp1r15b)

TNG:	GSTEN00004550G001

LCO:	104921782 104937641

NCC:	104952245 104967023

TBEN:

117471969 117497269(ppp1r15b)

CGOB:

115010133(ppp1r15b)

PGEO:

117442593(ppp1r15b) 117447873

GACU:

117557459(ppp1r15b) 117560032

EMAC:

134875263(ppp1r15b) 134882932

ELY:	117257057 117262280(ppp1r15b)

EFO:	125886903(ppp1r15b) 125889297

PLEP:

121940015 121949935(ppp1r15b)

SLUC:

116046817(ppp1r15b) 116061841

ECRA:

117949252(ppp1r15b)

ESP:

116693600

PFLV:

114554338 114560767

GAT:	120809528(ppp1r15b) 120812770 120834823

PPUG:

119196060(ppp1r15b) 119229443

AFB:	129105279 129108428(ppp1r15b)

CLUM:

117730408 117731820(ppp1r15b)

PSWI:

130195538(ppp1r15b) 130208845

CANA:

137796538 137799788

CVE:	137880662 137881614

MSAM:

119885765 119893538(ppp1r15b)

SCHU:

122874589(ppp1r15b) 122886256

CUD:	121506325 121514925(ppp1r15b)

SPUL:

138606485(ppp1r15b) 138613355

LMIX:

132972914(ppp1r15b) 132977172

HTC:	141796086 141807092(ppp1r15b)

ALAT:

119020743 119024079(ppp1r15b)

ASTR:

137593881 137594824

MZE:	101464720 101481200

ONL:	100696563 102082074

OAU:	116313965(ppp1r15b) 116322117

OLA:	101162120 101163073

OML:	112144996 112151967(ppp1r15b)

CSAI:

133443679(ppp1r15b) 133448944

XMA:	102218496 102222546

XCO:	114135880 114158456

XHE:	116709822 116710327 116736758

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122834524 122835870(ppp1r15b)

PPRL:

129355147 129363699(ppp1r15b)

CVG:	107090891 107101534

CTUL:

119789735(ppp1r15b) 119794292

GMU:	124855498(ppp1r15b) 124856833

NFU:	107384853 107388361

KMR:	108245708(ppp1r15b)

ALIM:

106522807 106525738

NWH:	119412028 119415422(ppp1r15b)

AOCE:

111579024(ppp1r15b)

EJA:	138206315 138214073(ppp1r15b)

BFRE:

138619160 138630048(ppp1r15b)

MCEP:

125006963 125014974(ppp1r15b)

CSEM:

103379822 107989203(ppp1r15b)

POV:	109624123 109645585

SSEN:

122768672 122776459(ppp1r15b)

SSOE:

131461326 131470210(ppp1r15b)

HHIP:

117762144 117763657(ppp1r15b) 117763665

HSP:	118104783 118109413 118109610

PPLT:

128444213 128444740(ppp1r15b) 128456697

SMAU:

118309023 118315307(ppp1r15b)

LCF:	108889306(ppp1r15b) 108890680

SDU:	111219387 111229669

SLAL:

111650447 111656522

XGL:	120793664(ppp1r15b) 120807438

HCQ:	109522579 109530841

SSCV:

125970933

SBIA:

133502687(ppp1r15b) 133507897

PEE:	133403364(ppp1r15b)

PTAO:

133478248(ppp1r15b) 133483151

BPEC:

110160331 110174614

ENY:

140349179

MALB:

109956436 109966916

BSPL:

114856197 114857655(ppp1r15b)

SJO:	128358741(ppp1r15b)

SSCO:

133982042(ppp1r15b)

TTY:	137183443(ppp1r15b)

GMH:	115551439 115556974

SASA:

106561078 106565097 106583502 106584628

STRU:

115150310 115192792 115197085 115197086 115208125

OTW:	112215528(ppp1r15b) 112218266 112244877 112254851

OMY:	110492175 110494057 110528365

OGO:	124002955 124029044 124037556 124039538

ONE:	115117972 115134513 115142938 115144718

OKI:	109866935 109891300 109893155

OKE:	118359345 118373454 118380883 118396415

OMM:	135509610 135539736 135541640 135556658(ppp1r15b)

OCLA:

139368971 139370868 139406410 139413712

SALP:

111962119 111963564 111970338 111971780

SNH:	120052355(ppp1r15b) 120062984 120065324 120066098

SFON:

129815252 129843366 129854996(ppp1r15b) 129862778

CCLU:

121532077 121540717 121575401 121578143

ELS:	105016799(ppp1r15b) 105018469

OEP:	134017173 134021349(ppp1r15b)

SFM:	108938165(ppp1r15b) 108938946

PKI:	111838685 111842400

AANG:

118211287 118214693(ppp1r15b)

AROT:

135237339 135242554(ppp1r15b)

CCOG:

133110109 133111847(ppp1r15b)

LOC:	102691328(ppp1r15b) 102693464

PSPA:

121294931 121299960 121304723 121321702(ppp1r15a) 121330360

ARUT:

117421300 117421301 117432178 117434044 117434815 117966037

LCM:	102359376(PPP1R15B) 102359668

CMK:	103174902(ppp1r15b) 103182443

RTP:	109913829 109915578 109917152

CPUN:

SCAU:

LERI:

PJA:

SDM:

OSN:

Reference

PMID:14638860

Authors

Jousse C, Oyadomari S, Novoa I, Lu P, Zhang Y, Harding HP, Ron D

Title

Inhibition of a constitutive translation initiation factor 2alpha phosphatase, CReP, promotes survival of stressed cells.

Journal

J Cell Biol 163:767-75 (2003)
DOI:10.1083/jcb.200308075

Sequence

[mmu:108954]

LinkDB

DBGET integrated database retrieval system