KEGG ORTHOLOGY: K17577

ORTHOLOGY: K17577

Entry

K17577                      KO

Symbol

SH2D4A

Name

SH2 domain-containing protein 4A

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09181 Protein families: metabolism
   01009 Protein phosphatases and associated proteins
    K17577  SH2D4A; SH2 domain-containing protein 4A
  09183 Protein families: signaling and cellular processes
   04990 Domain-containing proteins not elsewhere classified
    K17577  SH2D4A; SH2 domain-containing protein 4A
Protein phosphatases and associated proteins [BR:ko01009]
Protein serine/threonine phosphatases
  Phosphoprotein phosphatases (PPPs)
   Protein phosphatase-1
    PP1-interacting proteins (PIPs)
     K17577  SH2D4A; SH2 domain-containing protein 4A
Domain-containing proteins not elsewhere classified [BR:ko04990]
Src homology (SH) domain-containing proteins
  Other SH2 and SH3-containing proteins
   K17577  SH2D4A; SH2 domain-containing protein 4A

Genes

HSA:	63898(SH2D4A)

PTR:	464029(SH2D4A)

PPS:	100988944(SH2D4A)

GGO:	101127407(SH2D4A)

PON:	100441925(SH2D4A)

NLE:	100582431(SH2D4A)

HMH:	116473759(SH2D4A)

MCC:	704682(SH2D4A)

MCF:	102125285(SH2D4A)

MTHB:

126961449

MNI:	105482128(SH2D4A)

CSAB:

103215412(SH2D4A)

CATY:

105579261(SH2D4A)

PANU:

101013348(SH2D4A)

TGE:	112630627(SH2D4A)

MLEU:

105539378(SH2D4A)

RRO:	104662460(SH2D4A)

RBB:	108526481(SH2D4A)

TFN:	117092804(SH2D4A)

PTEH:

111545764(SH2D4A)

CANG:

105510155(SH2D4A)

CJC:	100407368(SH2D4A)

SBQ:	101048558(SH2D4A)

CIMI:

108312006(SH2D4A)

CSYR:

103276586(SH2D4A)

MMUR:

105882549(SH2D4A)

LCAT:

123626386(SH2D4A)

PCOQ:

105825291(SH2D4A)

OGA:	100949152(SH2D4A)

MMU:	72281(Sh2d4a)

MCAL:

110300295(Sh2d4a)

MPAH:

110336966(Sh2d4a)

RNO:	306376(Sh2d4a)

MCOC:

116069407(Sh2d4a)

ANU:	117721609(Sh2d4a)

MUN:	110549136(Sh2d4a)

CGE:	100754675(Sh2d4a)

MAUA:

101828997(Sh2d4a)

PROB:

127220206(Sh2d4a)

PLEU:

114703122(Sh2d4a)

MORG:

121462880(Sh2d4a)

MFOT:

126491325

AAMP:

119813507(Sh2d4a)

NGI:	103747617(Sh2d4a)

HGL:	101699922(Sh2d4a)

CPOC:

100725168(Sh2d4a)

CCAN:

109688881(Sh2d4a)

DORD:

105991015(Sh2d4a)

DSP:	122125689(Sh2d4a)

PLOP:

125339279(Sh2d4a)

NCAR:

124983958

MMMA:

107153955(Sh2d4a)

OCU:

103350657

OPI:	101522819(SH2D4A)

TUP:	102490372(SH2D4A)

GVR:	103603621(SH2D4A)

CFA:	475564(SH2D4A)

CLUD:

112659877(SH2D4A)

VVP:	112916172(SH2D4A)

VLG:	121489676(SH2D4A)

NPO:	129516001(SH2D4A)

AML:	100468495(SH2D4A)

UMR:	103677035(SH2D4A)

UAH:	113245557(SH2D4A)

UAR:	123780303(SH2D4A)

ELK:

111144600

LLV:

125092822

MPUF:

101674223(SH2D4A)

MNP:	132006479(SH2D4A)

MLK:	131820518(SH2D4A)

NVS:	122889842(SH2D4A)

ORO:	101377374(SH2D4A)

EJU:	114224835(SH2D4A)

ZCA:	113925915(SH2D4A)

MLX:	118009901(SH2D4A)

NSU:	110573169(SH2D4A)

LWW:	102735377(SH2D4A)

FCA:	101096059(SH2D4A)

PYU:	121009806(SH2D4A)

PCOO:

112858530(SH2D4A)

PBG:	122472776(SH2D4A)

PVIV:

125164266(SH2D4A)

LRUF:

124519946

PTG:	102956532(SH2D4A)

PPAD:

109262243(SH2D4A)

PUC:

125923844

AJU:

106978256

HHV:	120234011(SH2D4A)

BTA:	506242(SH2D4A)

BOM:	102266828(SH2D4A)

BIU:	109553565(SH2D4A)

BBUB:

102406572(SH2D4A)

BBIS:

104993237(SH2D4A)

CHX:	102179631(SH2D4A)

OAS:	101102533(SH2D4A)

BTAX:

128068292(SH2D4A)

ODA:	120865871(SH2D4A)

CCAD:

122432578(SH2D4A)

MBEZ:

129549448(SH2D4A)

SSC:

100518097

CFR:	102510541(SH2D4A)

CBAI:

105071150(SH2D4A)

CDK:	105086443(SH2D4A)

VPC:	102525336(SH2D4A)

BACU:

103012120(SH2D4A)

BMUS:

118887935(SH2D4A)

LVE:	103069184(SH2D4A)

OOR:	101290016(SH2D4A)

DLE:	111173569(SH2D4A)

PCAD:

102982794(SH2D4A)

PSIU:

116746737(SH2D4A)

NASI:

112413116(SH2D4A)

ECB:	100052071(SH2D4A)

EPZ:	103541885(SH2D4A)

EAI:	106824859(SH2D4A)

MYB:	102244859(SH2D4A)

MYD:	102768635(SH2D4A)

MMYO:

118651295(SH2D4A)

MLF:	102435452(SH2D4A)

PKL:	118730872(SH2D4A)

EFUS:

103288198(SH2D4A)

MNA:	107523898(SH2D4A)

DRO:

112321435

SHON:

118984281(SH2D4A)

AJM:	119060959(SH2D4A)

PDIC:

114508605(SH2D4A)

PHAS:

123807605(SH2D4A)

MMF:	118622838(SH2D4A)

PPAM:

129064776(SH2D4A) 129083428

HAI:	109386289(SH2D4A)

RFQ:	117021035(SH2D4A)

PALE:

102889496(SH2D4A)

PGIG:

120613136(SH2D4A)

PVP:	105300720(SH2D4A)

RAY:	107505768(SH2D4A)

MJV:	108403395(SH2D4A)

TOD:	119257868(SH2D4A)

SARA:

101551184(SH2D4A)

SETR:

126006435(SH2D4A)

LAV:	100653752(SH2D4A)

TMU:

101345387

ETF:	101660470(SH2D4A)

DNM:	101446996(SH2D4A)

MDO:	100030323(SH2D4A)

GAS:	123236971(SH2D4A)

SHR:	100925658(SH2D4A)

AFZ:

127548293

PCW:	110196404(SH2D4A)

OAA:	100077956(SH2D4A)

GGA:	422487(SH2D4A)

PCOC:

116238087(SH2D4A)

MGP:

100540221

CJO:	107313217(SH2D4A)

LMUT:

125692140(SH2D4A)

NMEL:

110397664(SH2D4A)

APLA:

101799317(SH2D4A)

ACYG:

106035186(SH2D4A)

CATA:

118249649(SH2D4A)

AFUL:

116489110(SH2D4A)

TGU:	100225429(SH2D4A)

LSR:	110471731(SH2D4A)

SCAN:

103826249(SH2D4A)

PMOA:

120502750(SH2D4A)

OTC:	121331372(SH2D4A)

PRUF:

121360264(SH2D4A)

GFR:	102033315(SH2D4A)

FAB:	101811966(SH2D4A)

OMA:	130252379(SH2D4A)

PHI:	102113609(SH2D4A)

PMAJ:

107203354(SH2D4A)

CCAE:

111944215(SH2D4A)

CCW:	104697138(SH2D4A)

CBRC:

103617405(SH2D4A)

ETL:	114062183(SH2D4A)

ZAB:	102062646(SH2D4A)

ACHL:

103810930(SH2D4A)

SVG:	106862849(SH2D4A)

MMEA:

130576245(SH2D4A)

HRT:	120753217(SH2D4A)

FPG:	101910296(SH2D4A)

FCH:	102059261(SH2D4A)

CLV:	102088795(SH2D4A)

EGZ:	104135541(SH2D4A)

NNI:	104021151(SH2D4A)

PCRI:

104037365(SH2D4A)

PLET:

104616905(SH2D4A)

EHS:	104516032(SH2D4A)

PCAO:

104042335(SH2D4A)

ACUN:

113479812(SH2D4A)

TALA:

104358410(SH2D4A)

PADL:

103925417(SH2D4A)

AFOR:

103894251(SH2D4A)

ACHC:

115343763(SH2D4A)

HALD:

104325279(SH2D4A)

HLE:	104843362(SH2D4A)

AGEN:

126044868

GCL:

127015906

CCRI:

104169285(SH2D4A)

CSTI:

104557408(SH2D4A)

CMAC:

104481246(SH2D4A)

MUI:	104540652(SH2D4A)

BREG:

104640023(SH2D4A)

FGA:	104071186(SH2D4A)

GSTE:

104256128(SH2D4A)

LDI:	104343716(SH2D4A)

MNB:	103782129(SH2D4A)

OHA:	104329199(SH2D4A)

NNT:	104410666(SH2D4A)

SHAB:

115610884(SH2D4A)

DPUB:

104298032(SH2D4A)

PGUU:

104465115(SH2D4A)

ACAR:

104528379(SH2D4A)

CPEA:

104398807(SH2D4A)

AVIT:

104272204(SH2D4A)

CVF:	104282994(SH2D4A)

RTD:	128910290(SH2D4A)

CUCA:

104064686(SH2D4A)

TEO:

104371031

BRHI:

104500085(SH2D4A)

AAM:	106484346(SH2D4A)

AROW:

112972175(SH2D4A)

NPD:	112953449(SH2D4A)

TGT:	104577667(SH2D4A)

DNE:	112993253(SH2D4A)

SCAM:

104152071(SH2D4A)

ASN:	102368047(SH2D4A)

AMJ:	102562892(SH2D4A)

CPOO:

109309423(SH2D4A)

GGN:	109301224(SH2D4A)

PSS:	102446693(SH2D4A)

CMY:	102947681(SH2D4A)

CCAY:

125635825(SH2D4A)

DCC:	119855161(SH2D4A)

CPIC:

101951462(SH2D4A)

TST:	117877840(SH2D4A)

CABI:

116834468(SH2D4A)

MRV:	120407092(SH2D4A)

ACS:	100567466(sh2d4a)

ASAO:

132778432(SH2D4A)

PVT:	110086349(SH2D4A)

SUND:

121932410(SH2D4A)

PBI:

103048395

PMUR:

107302379(SH2D4A)

CTIG:

120302659(SH2D4A)

TSR:	106549280(SH2D4A)

PGUT:

117664779(SH2D4A)

APRI:

131196945(SH2D4A)

PTEX:

113447281(SH2D4A)

NSS:	113420103(SH2D4A)

PMUA:

114581526(SH2D4A)

PRAF:

128400666(SH2D4A)

ZVI:	118079434 118095374(SH2D4A)

HCG:	128329112(SH2D4A)

GJA:	107107026(SH2D4A)

STOW:

125441042(SH2D4A)

EMC:	129337428(SH2D4A)

XLA:	108706823(sh2d4a.S) 108712231(sh2d4a.L)

XTR:	780161(sh2d4a)

NPR:	108804919(SH2D4A)

RTEM:

120914602(SH2D4A)

BBUF:

120989660(SH2D4A)

BGAR:

122945839(SH2D4A)

MUO:	115463755(SH2D4A)

GSH:	117346017(SH2D4A)

DRE:	393219(sh2d4a) 436899(zgc:92242) 445149(zgc:100829)

SRX:	107715408 107715862 107718492 107733519 107740790 107758528

SANH:

107660162 107665475 107670043(sh2d4a) 107684728 107693697

SGH:	107557060 107564121 107566901 107574531 107589098

CCAR:

109055708 109059662 109059726 109071236

CAUA:

113038478 113053977 113057693 113064070 113109512 113113742

CGIB:

127941560 127965978 127986580(zgc:100829) 128021552 128027663(zgc:92242)

PTET:

122326578(zgc:100829) 122352775(sh2d4a) 122357959

LROH:

127152931(zgc:100829) 127171849(sh2d4a) 127175908(zgc:92242)

OMC:	131529205(zgc:100829) 131548271(sh2d4a) 131553270(zgc:92242)

PPRM:

120460898(zgc:92242) 120482356(sh2d4a) 120494644(zgc:100829)

RKG:	130084750(zgc:92242) 130095309(zgc:100829) 130099753(sh2d4a)

MAMB:

125252663 125256195(sh2d4a) 125259185(zgc:92242)

CIDE:

127494688(zgc:92242) 127503289(zgc:100829) 127519948

MASI:

127413297(zgc:92242) 127418040 127428488 127431261 127432460 127433377

TROS:

130546137(sh2d4a) 130564011(zgc:92242) 130570400(zgc:100829)

TDW:	130408047(zgc:100829) 130411571(sh2d4a) 130437675(zgc:92242)

MANU:

129422060(zgc:92242) 129423917(zgc:100829) 129446190(sh2d4a)

IPU:	108275394(zgc:92242) 108277092 108279072(zgc:100829)

IFU:	128618316(zgc:92242) 128620564(sh2d4a) 128622371(zgc:100829)

PHYP:

113530171 113541594 113543492

SMEO:

124392736(zgc:92242) 124393423(sh2d4a) 124397740(zgc:100829)

TFD:	113639323(sh2d4a) 113648860(zgc:100829) 113654960(zgc:92242)

TVC:	132857012(zgc:92242) 132859646 132863451(sh2d4a)

AMEX:

103037091 103039948(sh2d4a) 103045283

CMAO:

118801445(zgc:92242) 118820224(zgc:100829) 118824382(sh2d4a)

EEE:	113576772(sh2d4a) 113581720 113585271

CHAR:

105894656(sh2d4a) 105897444(zgc:92242) 116222923

TRU:	101075091 115252797

TFS:	130537362(zgc:100829)

LCO:	104920564 104924605

NCC:	104948137 104957922

TBEN:

117490418(zgc:100829)

CGOB:

115018443

PGEO:

117458584(puraa)

GACU:

117535809(zgc:100829)

EMAC:

134871565(zgc:100829)

ELY:	117246418(zgc:100829)

EFO:	125898346(zgc:100829)

PLEP:

121952576(zgc:100829)

SLUC:

116064746(zgc:100829)

ECRA:

117955874(zgc:100829)

ESP:

116700960

PFLV:

114566631

GAT:

120821392

PPUG:

119215856(zgc:100829)

AFB:

129113621

CLUM:

117742557(zgc:100829)

PSWI:

130188351(zgc:100829)

MSAM:

119888832(zgc:92242) 119896007

SCHU:

122879826(zgc:92242) 122888477

CUD:	121519338(zgc:100829)

ALAT:

119030692(zgc:100829)

MZE:	101471217 101479279

ONL:	100712013 102077000

OAU:	116329449(zgc:92242) 116336213(zgc:100829)

OLA:

101164334

OML:

112138829

CSAI:

133459657(zgc:100829)

XMA:	102218800 102236187

XCO:	114139360 114153407

XHE:	116714528 116728613

PRET:

PFOR:

PLAI:

PMEI:

GAF:	122837234 122844439(zgc:100829)

PPRL:

129368811(zgc:100829)

CVG:	107082374 107089822

CTUL:

119775864(zgc:100829)

GMU:	124875893(zgc:100829)

NFU:	107380777 107386392

KMR:	108237028 108237930

ALIM:

106514058 106531462

NWH:

119420593

AOCE:

111567123 111567608

MCEP:

125021148(zgc:100829)

CSEM:

103391293 103395783

POV:	109628283 109631038

SSEN:

HHIP:

HSP:

SMAU:

LCF:	108878703(zgc:92242) 108893853(zgc:100829)

SDU:	111226633 111234463

SLAL:

111646514 111666208

XGL:	120785822(zgc:92242) 120802944(zgc:100829)

HCQ:	109517843 109524314

SSCV:

125982560(zgc:100829)

SBIA:

133492316(zgc:100829)

PEE:	133416032(zgc:100829)

PTAO:

133466981(zgc:100829)

BPEC:

110153932 110158617

MALB:

109957476 109959382

BSPL:

114869687(zgc:100829)

SJO:	128371347(zgc:100829)

SASA:

100195479(sh2d4a) 106604401 106612115

STRU:

115160082(sh2d4a) 115169050

OTW:	112220141(sh2d4a) 112221180(zgc:92242) 112233822(zgc:100829) 112255955

OMY:	110489087 110504673 110523174(sh2d4a)

OGO:	123989489(sh2d4a) 123994147(zgc:92242) 124006334 124011448

ONE:	115118212(sh2d4a) 115118655 115135516

OKI:	109868571(sh2d4a) 109872979 109874279 109910246 116353571

OKE:	118373526 118377940 118384997 118387267(sh2d4a) 118390490

SALP:

111961939 111965966

SNH:	120025441(sh2d4a) 120047962(zgc:92242) 120057310 120062449

CCLU:

121536852 121539846(zgc:92242) 121581978(sh2d4a)

ELS:	105021726(sh2d4a) 105026744

SFM:	108922972 108929941(sh2d4a) 108934143

PKI:	111836062 111836413 111853008

AANG:

118213424(sh2d4a) 118224124 118236100

LOC:	102683025(sh2d4a)

PSPA:

121297095 121301006(sh2d4a) 121316705 121324107

ARUT:

117409602 117413039 117431200 117963652

PSEX:

120532613(sh2d4a)

LCM:	102366085 102367056(SH2D4A)

CMK:	103186732(sh2d4a)

RTP:	109922358(sh2d4a)

CPLA:

122539456(sh2d4a)

HOC:	132833363(sh2d4a)

CIN:

SCLV:

APLC:

CNS:

BCOO:

TCA:

DPA:

SOY:

AGRG:

ATD:

CSET:

NVL:

APLN:

PPYR:

BMOR:

BMAN:

MSEX:

DPL:	KGM_200984

BANY:

MJU:

NIQ:

VCD:

MCIX:

PMAC:

PPOT:

PXU:

PRAP:

PBX:

PNAP:

ZCE:

CCRC:

LSIN:

AAGE:

HAW:

HZE:

TNL:

SLIU:

OFU:

PXY:	105385742 105386180

PGW:

CCRN:

API:

DNX:

AGS:

RMD:

BTAB:

CLEC:

NLU:

PHU:	Phum_PHUM494760

FOC:

TPAL:

ZNE:

CSEC:

BROR:

DSV:

RSAN:

RMP:

CEL:	CELE_F13B12.6(F13B12.6)

CBR:

CBG_08374

CRQ:	GCK72_014985

NAI:	NECAME_05227

LOA:	LOAG_18259

SMM:	Smp_138850

EGL:

EPA:

ADF:

AMIL:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

AQU:

MBR:	MONBRDRAFT_30425

SRE:	PTSG_04184

» show all

Reference

PMID:19712589

Authors

Li T, Li W, Lu J, Liu H, Li Y, Zhao Y

Title

SH2D4A regulates cell proliferation via the ERalpha/PLC-gamma/PKC pathway.

Journal

BMB Rep 42:516-22 (2009)
DOI:10.5483/bmbrep.2009.42.8.516

Sequence

[hsa:63898]

Reference

PMID:18641339

Authors

Lapinski PE, Oliver JA, Kamen LA, Hughes ED, Saunders TL, King PD

Title

Genetic analysis of SH2D4A, a novel adapter protein related to T cell-specific adapter and adapter protein in lymphocytes of unknown function, reveals a redundant function in T cells.

Journal

J Immunol 181:2019-27 (2008)
DOI:10.4049/jimmunol.181.3.2019

Sequence

[hsa:63898] [mmu:72281]

LinkDB

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