KEGG   ORTHOLOGY: K17651
Entry
K17651                      KO                                     
Symbol
ORDA, CYP64A
Name
aflatoxin B synthase [EC:1.14.14.117]
Pathway
map00254  Aflatoxin biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00937  Aflatoxin biosynthesis, malonyl-CoA => aflatoxin B1
Reaction
R10319  8-O-methylsterigmatocystin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (aflatoxin-B forming)
R10320  8-O-methyldihydrosterigmatocystin,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (aflatoxin-B forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00254 Aflatoxin biosynthesis
    K17651  ORDA, CYP64A; aflatoxin B synthase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17651  ORDA, CYP64A; aflatoxin B synthase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.117  aflatoxin B synthase
     K17651  ORDA, CYP64A; aflatoxin B synthase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP64 family
   K17651  ORDA, CYP64A; aflatoxin B synthase
Other DBs
COG: COG2124
GO: 0140399
Genes
AOR: AO090026000027
AFV: AFLA_006290
APUU: APUU_50251A
AG: AAS66031(ORDA)
Reference
PMID:9835571
  Authors
Yu J, Chang PK, Ehrlich KC, Cary JW, Montalbano B, Dyer JM, Bhatnagar D, Cleveland TE
  Title
Characterization of the critical amino acids of an Aspergillus parasiticus cytochrome P-450 monooxygenase encoded by ordA that is involved in the biosynthesis of aflatoxins B1, G1, B2, and G2.
  Journal
Appl Environ Microbiol 64:4834-41 (1998)
DOI:10.1128/AEM.64.12.4834-4841.1998
  Sequence
[ag:AAS66031]
LinkDB

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