KEGG ORTHOLOGY: K17682

ORTHOLOGY: K17682

Entry

K17682                      KO

Symbol

MNF1

Name

mitochondrial nucleoid factor 1

Disease

H02086

Mitochondrial complex III deficiency

Brite

KEGG Orthology (KO) [BR:ko00001]
09180 Brite Hierarchies
  09182 Protein families: genetic information processing
   03029 Mitochondrial biogenesis
    K17682  MNF1; mitochondrial nucleoid factor 1
Mitochondrial biogenesis [BR:ko03029]
Mitochondrial DNA transcription, translation, and replication factors
  Mitochondrial DNA replication factors
   Other Mitochondrial DNA replication factors
    K17682  MNF1; mitochondrial nucleoid factor 1
Mitochondrial quality control factors
  Mitochondrial respiratory chain complex assembly factors
   Complex-III assembly factors
    K17682  MNF1; mitochondrial nucleoid factor 1

Genes

HSA:	84300(UQCC2)

PTR:	100615289(UQCC2)

PPS:

GGO:

PON:

PPYG:

NLE:

HMH:

SSYN:

MCC:	100425666(C6orf125)

MCF:	102115611(UQCC2)

MNI:

105474471

CSAB:

103221650(UQCC2)

CATY:

PANU:

TGE:

MLEU:

RRO:

RBB:

TFN:

PTEH:

CANG:

CJC:	100390120(MNF1)

SBQ:

CIMI:

ANAN:

CSYR:

MMUR:

LCAT:

PCOQ:

OGA:

MMU:	67267(Uqcc2)

MCAL:

110283871

MPAH:

110338333

RNO:	361805(Uqcc2)

MCOC:

ANU:

ASYL:

MUN:

CGE:

MAUA:

PROB:

PLEU:

PMAV:

102914201(Uqcc2)

MORG:

MFOT:

AAMP:

NGI:

HGL:	101706352(Mnf1)

CPOC:

CCAN:

DORD:

DSP:

DMER:

138828157(Uqcc2)

PLOP:

NCAR:

MMMA:

ITI:

OCU:

OPI:

OCZ:	121158495 121169246

TUP:

102491235

GVR:

103597697

CFA:	100683221(UQCC2)

CLUD:

VVP:

VLG:

NPO:

AML:	105235434 105235619

UMR:	103665552 103673307

UAH:	113243815 113269984

UAR:

ELK:

LLV:

MPUF:

MNP:

MLK:

NVS:

ORO:

EJU:

ZCA:

MLX:

NSU:

LWW:

FCA:	101093686(UQCC2)

PYU:

PCOO:

PBG:

PVIV:

LRUF:

LGF:

AJU:

PTG:

PPAD:

PUC:

PLEZ:

HHV:

BTA:	100607974(UQCC2)

BOM:	102271328(UQCC2)

BIU:

BBUB:

BBIS:

CHX:

OAS:

CSUM:

138069501(UQCC2)

ODA:

120869825

CCAD:

122430153

MREE:

136151888(UQCC2)

OVR:	110130149(UQCC2)

MBEZ:

129543848

SSC:	100153818(C7H6orf125)

CFR:

CBAI:

CDK:

VPC:

BACU:

BMUS:

LVE:

OOR:	101273572 101280641

LALB:

132527250

GMF:	115860820(UQCC2)

DDP:	132432084(UQCC2)

DLE:

111178695

PCAD:

102980429 102992571

PSIU:

116751062 116761677

PPHC:

136129193(UQCC2)

NASI:

112414024

ECB:

100146183

EPZ:	103564723(UQCC2)

EAI:

MYB:

MYD:

MMYO:

MLF:

MDT:

MYUM:

139012613(UQCC2)

PKL:

EFUS:

MNA:

DRO:

SHON:

AJM:

PDIC:

PHAS:

MMF:

PPAM:

HAI:

RFQ:

PALE:

PGIG:

PVP:

RAY:

MJV:

TOD:

SARA:

SFUM:

SETR:

LAV:

TMU:

ETF:	105979081 123521960

DNM:

MDO:

GAS:

SHR:

AFZ:

PCW:

TVP:

PBRV:

138150083(UQCC2)

MLAO:

141523387(UQCC2)

OAA:

100681553

TACU:

119930916

GGA:	419909(C26H6ORF125)

PCOC:

MGP:

CJO:

TPAI:

LMUT:

NMEL:

APLA:

ACYG:

106046121(UQCC2)

CATA:

118259511

AFUL:

116498949

TGU:

100230361

LSR:	110477150(UQCC2)

SCAN:

PMOA:

OTC:

PRUF:

ATRC:

139601124(UQCC2)

GFR:	102036559(MNF1)

FAB:	101809875(MNF1)

OMA:

PHI:

PMAJ:

CCAE:

CCW:

CBRC:

ACOE:

138098836(UQCC2)

ETL:

ZAB:

ZLE:

ACHL:

SVG:

MMEA:

HRT:

SATI:

136371583(UQCC2)

CCIC:

134054170

FPG:	101924058(MNF1)

FCH:

CCRI:

NNT:

SHAB:

ACUN:

TALA:

ACHC:

HALD:

HLE:

AGEN:

HHAR:

GCL:

CSTI:

LDI:

MNB:

DPUB:

PPUS:

AVIT:

BRHI:

EGZ:

NNI:

PCRI:

PCAO:

PADL:

AFOR:

FGA:

CBOR:

142093199(UQCC2)

GSTE:

104263843

CBOY:

140643277(UQCC2)

MAME:

142419114(UQCC2)

CLV:

CNIC:

MUI:

PGUU:

PLET:

EHS:

CMAC:

CUCA:

TEO:

BREG:

OHA:

ACAR:

CPEA:

CVF:

RTD:

CRID:

LMIC:

141733762(UQCC2)

AAM:

AROW:

NPD:

TGT:

DNE:

SCAM:

ASN:

AMJ:	102566860(MNF1)

CPOO:

109317805

GGN:

109295369

PSS:

102447993

CIZ:	142002017(UQCC2)

CMY:

CCAY:

DCC:

CPIC:

TST:

CABI:

MRV:	120403537 120403769

ACS:	100564253(mnf1)

ASAO:

PVT:

SUND:

PBI:

PMUR:

CTIG:

TSR:

PGUT:

PCAE:

139315317(UQCC2)

PTEX:

NSS:

VKO:

PMUA:

PRAF:

ZVI:

HCG:

GJA:	107117571 107124996

STOW:

125432439

EMC:

129330752

XLA:	379072(uqcc2.L) 443971(uqcc2.S)

XTR:	779699(uqcc2)

NPR:

108787279

RTEM:

120927257

ACAT:

141128639(UQCC2)

PADS:

140338373(UQCC2)

BBUF:

120993752

BGAR:

122932693

DTC:	141089285(UQCC2)

PWL:	138300029(UQCC2)

MUO:

115481324

GSH:	117347283 117347300 117364628

DRE:	393731(uqcc2)

SRX:	107712081 107721167

SANH:

SGH:

CCAR:

CAUA:

CGIB:

PTET:

LROH:

GRF:	141347151(uqcc2)

OMC:

PPRM:

RKG:

MAMB:

CIDE:

CERY:

137011471(uqcc2)

MASI:

127446181 127449317

TROS:

130556391

TDW:

130424934

MANU:

129450556(uqcc2)

PDAB:

135746241(uqcc2)

IPU:	100528072(cf125)

IFU:

PHYP:

SMEO:

TFD:

TVC:

CGAR:

NGRA:

TRN:

AMEX:

CMAO:

EEE:

CHAR:

SPIL:

TRU:

TFS:

TNG:	GSTEN00027430G001

LCO:

NCC:

TBEN:

CGOB:

PGEO:

117447054(uqcc2)

GACU:

EMAC:

ELY:

EFO:

PLEP:

SLUC:

ECRA:

ESP:

PFLV:

GAT:

PPUG:

AFB:

CLUM:

PSWI:

CANA:

137796564(uqcc2)

CVE:	137873747(uqcc2)

MSAM:

119885924

SCHU:

122864964

CUD:

121507385

SPUL:

138605593(uqcc2)

LMIX:

132977914

HTC:	141795010(uqcc2)

ALAT:

119021423

ASTR:

137595185(uqcc2)

MZE:

ONL:

OAU:

OLA:

OML:

CSAI:

XMA:

XCO:

XHE:

PRET:

PFOR:

PLAI:

PMEI:

GAF:

PPRL:

CVG:

CTUL:

GMU:

NFU:

KMR:

ALIM:

NWH:

AOCE:

EJA:	138194928(uqcc2)

BFRE:

138616405(uqcc2)

MCEP:

CSEM:

POV:

SSEN:

SSOE:

HHIP:

HSP:

PPLT:

SMAU:

LCF:

SDU:

SLAL:

XGL:

HCQ:

SSCV:

125977134(uqcc2)

SBIA:

PEE:

PTAO:

BPEC:

ENY:	140365829(uqcc2)

MALB:

BSPL:

SJO:

SSCO:

TTY:	137181467(uqcc2)

GMH:

115547713

SASA:

100195839(cf125) 106565356(CF125)

STRU:

115150363 115208064

OTW:	112215331 112254802

OMY:	110494110 110528312

OGO:	124002883 124029901

ONE:	115142005 115142983

OKI:	109891261 109893640

OKE:	118388771 118400472

OMM:	135539779 135541748

OCLA:

139370902 139413680

SALP:

111964163 111970292

SNH:	120062739 120064604

SFON:

CCLU:

ELS:

OEP:

SFM:

PKI:

AANG:

AROT:

CCOG:

LOC:

PSPA:

ARUT:

PSEX:

LCM:

CMK:

RTP:

CPLA:

CPUN:

140467274(uqcc2)

HOC:

132828212

SCAU:

119978947

LERI:

129708666

HAKA:

140717156(uqcc2)

PMRN:

LRJ:

BFO:

BBEL:

SPU:

LPIC:

LVG:

AJJ:

APLC:

ARUN:

AAMU:

AFIL:

AJC:

SKO:

PFLL:

AGA:

ACOZ:

AMAP:

AMRS:

ACOS:

AALB:

ASUA:

CBRI:

ALAB:

CGIG:

TLN:

VCRB:

VVE:

TPRE:

LBD:

CGLO:

VCAN:

AROA:

DPA:

SOY:

ATD:

DVV:

ONU:

CFUM:

CFEL:

CCRN:

BTAB:

DCI:

LDA:

PHU:	Phum_PHUM550750

PAME:

138708701

IEL:

124168243

FCD:

110843337

DPX:	DAPPUDRAFT_306028

AFRA:

PJA:

PCHN:

PMOO:

HAME:

PCLA:

PTRU:

ESN:

MNZ:

MRJ:

PORN:

TCF:

PPOI:

DSV:

DALB:

RSAN:

RMP:

VDE:

TUT:

DPTE:

DFR:

CSCU:

ABRU:

SDM:

LPOL:

CEL:	CELE_Y48A5A.3(Y48A5A.3)

CBR:

CBG_22511

CRQ:	GCK72_016046

NAI:	NECAME_14500

LOA:	LOAG_09326

LGI:	LOTGIDRAFT_202617

BGT:

GAE:

HRJ:

OED:

PMAX:

AIRR:

YBA:

MMER:

RPHI:

OSN:

LJP:

NVE:

ATEN:

ADF:

AMIL:

MCAZ:

MFOO:

PDAM:

SPIS:

DGT:

XEN:

HMG:

HSY:

TAD:	TRIADDRAFT_58385

AQU:

100633095

» show all

Reference

PMID:19643811

Authors

Sumitani M, Kasashima K, Ohta E, Kang D, Endo H

Title

Association of a novel mitochondrial protein M19 with mitochondrial nucleoids.

Journal

J Biochem 146:725-32 (2009)
DOI:10.1093/jb/mvp118

Sequence

[hsa:84300] [mmu:67267]

Reference

PMID:24385928

Authors

Tucker EJ, Wanschers BF, Szklarczyk R, Mountford HS, Wijeyeratne XW, van den Brand MA, Leenders AM, Rodenburg RJ, Reljic B, Compton AG, Frazier AE, Bruno DL, Christodoulou J, Endo H, Ryan MT, Nijtmans LG, Huynen MA, Thorburn DR

Title

Mutations in the UQCC1-interacting protein, UQCC2, cause human complex III deficiency associated with perturbed cytochrome b protein expression.

Journal

PLoS Genet 9:e1004034 (2013)
DOI:10.1371/journal.pgen.1004034

Sequence

[hsa:84300]

Reference

PMID:22363741

Authors

Cambier L, Rassam P, Chabi B, Mezghenna K, Gross R, Eveno E, Auffray C, Wrutniak-Cabello C, Lajoix AD, Pomies P

Title

M19 modulates skeletal muscle differentiation and insulin secretion in pancreatic beta-cells through modulation of respiratory chain activity.

Journal

PLoS One 7:e31815 (2012)
DOI:10.1371/journal.pone.0031815

Sequence

[hsa:84300] [mmu:67267]

LinkDB

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