KEGG   ORTHOLOGY: K17826
Entry
K17826                      KO                                     
Symbol
FTMG, CYP5067A
Name
fumitremorgin C monooxygenase [EC:1.14.14.119]
Pathway
map00404  Staurosporine biosynthesis
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00786  Fumitremorgin alkaloid biosynthesis, tryptophan + proline => fumitremorgin C/A
Reaction
R10414  fumitremorgin C,[reduced NADPH---hemoprotein reductase]:oxygen oxidoreductase (12alpha,13alpha-dihydroxyfumitremorgin C-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00404 Staurosporine biosynthesis
    K17826  FTMG, CYP5067A; fumitremorgin C monooxygenase
 09180 Brite Hierarchies
  09181 Protein families: metabolism
   00199 Cytochrome P450
    K17826  FTMG, CYP5067A; fumitremorgin C monooxygenase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.14  With reduced flavin or flavoprotein as one donor, and incorporation of one atom of oxygen into the other donor
    1.14.14.119  fumitremorgin C monooxygenase
     K17826  FTMG, CYP5067A; fumitremorgin C monooxygenase
Cytochrome P450 [BR:ko00199]
 Cytochrome P450, fungi type
  CYP5067 family
   K17826  FTMG, CYP5067A; fumitremorgin C monooxygenase
Other DBs
COG: COG2124
Genes
AFM: AFUA_8G00240
NFI: NFIA_093750
Reference
PMID:19226505
  Authors
Kato N, Suzuki H, Takagi H, Asami Y, Kakeya H, Uramoto M, Usui T, Takahashi S, Sugimoto Y, Osada H
  Title
Identification of cytochrome P450s required for fumitremorgin biosynthesis in Aspergillus fumigatus.
  Journal
Chembiochem 10:920-8 (2009)
DOI:10.1002/cbic.200800787
  Sequence
[afm:AFUA_8G00240]
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