Entry
Symbol
pyrDI
Name
dihydroorotate dehydrogenase (NAD+) catalytic subunit [EC:
1.3.1.14 ]
Pathway
Module
M00051 De novo pyrimidine biosynthesis, glutamine (+ PRPP) => UMP
Reaction
R01869 (S)-dihydroorotate:NAD+ oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001 ]
09100 Metabolism
09104 Nucleotide metabolism
00240 Pyrimidine metabolism
K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit
Enzymes [BR:ko01000 ]
1. Oxidoreductases
1.3 Acting on the CH-CH group of donors
1.3.1 With NAD+ or NADP+ as acceptor
1.3.1.14 dihydroorotate dehydrogenase (NAD+)
K17828 pyrDI; dihydroorotate dehydrogenase (NAD+) catalytic subunit
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Taxonomy UniProt
Reference
Authors
Nielsen FS, Andersen PS, Jensen KF
Title
The B form of dihydroorotate dehydrogenase from Lactococcus lactis consists of two different subunits, encoded by the pyrDb and pyrK genes, and contains FMN, FAD, and [FeS] redox centers.
Journal
Sequence
Reference
Authors
Kahler AE, Nielsen FS, Switzer RL
Title
Biochemical characterization of the heteromeric Bacillus subtilis dihydroorotate dehydrogenase and its isolated subunits.
Journal
Sequence
Reference
Authors
Marcinkeviciene J, Tinney LM, Wang KH, Rogers MJ, Copeland RA
Title
Dihydroorotate dehydrogenase B of Enterococcus faecalis. Characterization and insights into chemical mechanism.
Journal
Sequence
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