KEGG   ORTHOLOGY: K18000
Entry
K18000                      KO                                     
Symbol
pqsA
Name
anthranilate-CoA ligase [EC:6.2.1.32]
Pathway
map00405  Phenazine biosynthesis
map01110  Biosynthesis of secondary metabolites
map02024  Quorum sensing
map02025  Biofilm formation - Pseudomonas aeruginosa
Reaction
R00982  anthranilate:CoA ligase (AMP-forming)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00405 Phenazine biosynthesis
    K18000  pqsA; anthranilate-CoA ligase
 09140 Cellular Processes
  09145 Cellular community - prokaryotes
   02024 Quorum sensing
    K18000  pqsA; anthranilate-CoA ligase
   02025 Biofilm formation - Pseudomonas aeruginosa
    K18000  pqsA; anthranilate-CoA ligase
Enzymes [BR:ko01000]
 6. Ligases
  6.2  Forming carbon-sulfur bonds
   6.2.1  Acid-thiol ligases
    6.2.1.32  anthranilate---CoA ligase
     K18000  pqsA; anthranilate-CoA ligase
Other DBs
COG: COG0365
GO: 0018860
Genes
ELIT: AB8599_09590
PAE: PA0996(pqsA)
PAEV: N297_1029
PAEI: N296_1029
PAU: PA14_51430(pqsA)
PAG: PLES_43291(pqsA)
PAF: PAM18_4052(pqsA)
PNC: NCGM2_1850(pqsA)
PAEB: NCGM1900_1672(pqsA)
PDK: PADK2_20760
PSG: G655_20320
PRP: M062_05430
PAEP: PA1S_20990
PAER: PA1R_gp4593
PAEM: U769_20835
PAEL: T223_22115
PAES: SCV20265_4446
PAEU: BN889_01048(pqsA)
PAEG: AI22_12950
PAEC: M802_1026
PAEO: M801_1029
SECH: B18_16610
PAP: PSPA7_4402
PPAA: B7D75_20145
ZOB: ACEVBK_15210
COY: HF329_06230
CHII: UNH65_11915
 » show all
Reference
PMID:18728009
  Authors
Zhang YM, Frank MW, Zhu K, Mayasundari A, Rock CO
  Title
PqsD is responsible for the synthesis of 2,4-dihydroxyquinoline, an extracellular metabolite produced by Pseudomonas aeruginosa.
  Journal
J Biol Chem 283:28788-94 (2008)
DOI:10.1074/jbc.M804555200
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