KEGG   ORTHOLOGY: K18029
Entry
K18029                      KO                                     
Symbol
nicA
Name
nicotinate dehydrogenase subunit A [EC:1.17.2.1]
Pathway
map00760  Nicotinate and nicotinamide metabolism
map01100  Metabolic pathways
map01120  Microbial metabolism in diverse environments
Module
M00622  Nicotinate degradation, nicotinate => fumarate
Reaction
R09473  nicotinate:cytochrome 6-oxidoreductase (hydroxylating)
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09108 Metabolism of cofactors and vitamins
   00760 Nicotinate and nicotinamide metabolism
    K18029  nicA; nicotinate dehydrogenase subunit A
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.17  Acting on CH or CH2 groups
   1.17.2  With a cytochrome as acceptor
    1.17.2.1  nicotinate dehydrogenase (cytochrome)
     K18029  nicA; nicotinate dehydrogenase subunit A
Other DBs
COG: COG2080
Genes
IZH: FEM41_12580
SMAR: SM39_1773 SM39_1933
SMAC: SMDB11_1586 SMDB11_1757
SMW: SMWW4_v1c23280 SMWW4_v1c24890
SPE: Spro_2314 Spro_2492
SRR: SerAS9_2271
SRL: SOD_c21440(nicA)
SRY: M621_11745
SPLY: Q5A_011880(nicA)
SRS: SerAS12_2271
SRA: SerAS13_2272
SMAF: D781_1723
SLQ: M495_11515 M495_12385
SERF: L085_16260 L085_17105
SERS: SERRSCBI_11740
SFW: WN53_13065
SFG: AV650_08565
SRZ: AXX16_3400
SERM: CLM71_08340
SQU: E4343_03765 E4343_04620
SFJ: SAMEA4384070_2383(iorA_1)
SOF: NCTC11214_04486(iorA_2)
SSUR: ATE40_009130
SURI: J0X03_11475 J0X03_12355
SRHZ: FO014_01605
SENP: KHA73_12400
SNEM: NLX84_11790 NLX84_12620
SNEV: OI978_19660
GQU: AWC35_02965
EAME: GXP68_16300
EPE: CI789_03030
ERP: LJN55_16325
PAO: Pat9b_5173
TCI: A7K98_12055
TPTY: NCTC11468_02204(iorA)
PHEI: NCTC12003_00963(iorA)
PHAG: PZ638_04745
PFQ: QQ39_14990
PAE: PA1602
PAEV: N297_1647
PAEI: N296_1647
PAU: PA14_43780
PAP: PSPA7_3672
PAG: PLES_37251
PAF: PAM18_3445
PNC: NCGM2_2493
PAEB: NCGM1900_4972
PDK: PADK2_17700
PSG: G655_17200
PRP: M062_08540
PAEP: PA1S_18005
PAER: PA1R_gp5183
PAEM: U769_17735
PAEL: T223_19065
PAES: SCV20265_3810
PAEU: BN889_01715
PAEG: AI22_15975
PAEC: M802_1644
PAEO: M801_1646
PMUI: G4G71_18220
PNT: G5B91_13655
PPAA: B7D75_16870
PPU: PP_3947(nicA)
PPF: Pput_1890
PPG: PputGB1_3582
PPW: PputW619_2136
PPB: PPUBIRD1_1861
PPI: YSA_08961
PPX: T1E_2080
PPUT: L483_21725
PPUN: PP4_17750
POR: APT59_07070
PALD: LU682_010730
PFO: Pfl01_2447(iorA)
PFS: PFLU_2802
PFB: VO64_0129
PVR: PverR02_20840
PAZO: AYR47_21630
PKR: AYO71_17055
PTOL: I7845_13275
PFW: PF1751_v1c24730
PFF: PFLUOLIPICF724365
PFX: A7318_11815
PLUL: FOB45_13260
PSV: PVLB_10360
PSK: U771_14870 U771_21620
PCH: EY04_18455 EY04_20270
PCZ: PCL1606_21920
PCP: JM49_10940
PCHP: C4K32_4141
PFZ: AV641_08740
PSEM: TO66_20980
PANR: A7J50_2719
PPSL: BJP27_21875
PSIL: PMA3_12580
PYM: AK972_2678
PGG: FX982_03131 FX982_04197
PGY: AWU82_14920
PVK: EPZ47_17400
PEZ: HWQ56_12845
PATA: JWU58_13225
PZE: HU754_014620
PMOE: HV782_015340
PTZ: HU718_015445
PHV: HU739_004285
PANH: HU763_008055
PIE: HU724_015275
PWY: HU734_022670
PTAE: NCTC10697_01686(iorA)
PGF: J0G10_15900
PPEG: KUA23_13480
PSII: NF676_14285
PFIT: KJY40_14115
PNB: NK667_12105
PTAI: ICN73_23215
PPAE: LDL65_21520
PPAO: K3169_11270
PRHZ: CRX69_18195
PSJY: AA098_17800
PDEN: F1C79_05340
HAM: HALO0544
HAXI: HAALTHF_14270n
HSV: HNO53_05750
HPRO: LMS44_20670
HASO: B2G49_16080
HVN: EI420_01985
HOL: HORIV_65020
HNP: SR894_18990
HTT: HZS52_07560
HTX: EKK97_06035
ALCA: ASALC70_00119(nicA)
ADI: B5T_02299
MARS: A8C75_16290
RPJ: N234_04310
RIN: ACS15_2998(nicA)
REH: H16_A0921(h16_A0921)
CNC: CNE_1c08710(iorA1)
CUH: BJN34_04890 BJN34_29055
REU: Reut_A2516
CTI: RALTA_A0866
CBW: RR42_s0167
CGD: CR3_3011(nicA)
CCUP: BKK81_07350 BKK81_24775
CUP: BKK80_06650 BKK80_31590
CUU: BKK79_05500 BKK79_22475
CPAU: EHF44_26995
COX: E0W60_14750
CCAM: M5D45_06885
CCAX: KZ686_20195
CUK: KB879_04550 KB879_19225
CNAN: A2G96_05355
BOK: DM82_4532
BOC: BG90_6061
BUU: WS70_19570
BSAV: WS86_30260
BVI: Bcep1808_6385
BVE: AK36_5818
BUR: Bcep18194_A4957
BCM: Bcenmc03_3482 Bcenmc03_7023
BCH: Bcen2424_4043 Bcen2424_6357
BCJ: BCAM1147
BCEN: DM39_3875
BCEW: DM40_5851
BCEO: I35_4993 I35_7713
BAM: Bamb_5819
BAC: BamMC406_5602
BMJ: BMULJ_03964(coxS)
BMU: Bmul_4546
BMK: DM80_3716
BMUL: NP80_4073
BCED: DM42_3944 DM42_7239
BCEP: APZ15_36000
BDL: AK34_5643
BPYR: ABD05_32295
BCON: NL30_06900 NL30_31255
BUB: BW23_3
BDF: WI26_30560
BLAT: WK25_19440
BTEI: WS51_30330
BSEM: WJ12_20595 WJ12_25630
BPSL: WS57_08395 WS57_18195
BMEC: WJ16_24260
BSTG: WT74_19670 WT74_20845
BANN: JFN94_22975
BARI: NLX30_32965
BUG: BC1001_4281 BC1001_5752
BGF: BC1003_3912 BC1003_5119 BC1003_5623
BGD: bgla_1g12710
BGO: BM43_2603
BUK: MYA_5779
BUQ: AC233_28065
BGP: BGL_1c11640
BPLA: bpln_1g11160 bpln_1g19790
BUM: AXG89_36985 AXG89_39840
BUI: AX768_15605
BURK: DM992_20085 DM992_38550
BXE: Bxe_B0662
BXB: DR64_5993
BPH: Bphy_5704
BGE: BC1002_5511
BPX: BUPH_00865 BUPH_06043
BPY: Bphyt_4331 Bphyt_5505
BUZ: AYM40_28665 AYM40_29655 AYM40_31815
BFN: OI25_6349 OI25_6803
BCAI: K788_0005021 K788_0007377
PSPW: BJG93_19840 BJG93_23420 BJG93_25170
PARA: BTO02_16650 BTO02_29305
PARB: CJU94_26120 CJU94_31355
PHS: C2L64_08190 C2L64_45580
PTER: C2L65_30605
PGP: CUJ91_28150 CUJ91_32350
PCJ: CUJ87_18550 CUJ87_25410
PTS: CUJ90_21650 CUJ90_26315
PCAF: DSC91_000568
PMEG: FNZ07_07700 FNZ07_24550
PTRO: G5S35_31865 G5S35_35940
PEW: KZJ38_05555
PDIO: PDMSB3_0674.1(nicA) PDMSB3_2712.1(nicA)
PBRY: NDK50_24145
PSAA: QEN71_37470
PKF: RW095_10260 RW095_17630
PBON: QS306_00055
PPAI: E1956_29270 E1956_33335 E1956_34535 E1956_36105
PSPU: NA29_11660
PVE: UC34_12660
PNR: AT302_20375
CABA: SBC2_37450(nicA_1) SBC2_46130(nicA_2)
BUO: BRPE64_DCDS10950
CABK: NK8_47340
TVL: FAZ95_22870 FAZ95_31955
TCAR: U0034_25045
BPE: BP1953
BPC: BPTD_1925
BPER: BN118_0961
BPEU: Q425_14990
BPAR: BN117_1480
BPA: BPP2326
BBH: BN112_1738
BBR: BB1777
BBM: BN115_1679
BBX: BBS798_1678
BPT: Bpet3962
BAV: BAV1533(iorA)
BBRO: BAU06_19445 BAU06_19685
BFZ: BAU07_06765 BAU07_07000 BAU07_08025 BAU07_16155
BOH: AKI39_05180 AKI39_18970
BGM: CAL15_06255 CAL15_11490
BGV: CAL12_01140 CAL12_21405 CAL12_21725
AXO: NH44784_051871
AXN: AX27061_3324
AXX: ERS451415_03304(iorA_1)
ADT: APT56_16385
AIS: BUW96_28765
ASW: CVS48_09665
PUD: G9Q38_13520
AKA: TKWG_19815
AMIM: MIM_c31110
AFA: UZ73_14750
AFQ: AFA_14980(nicA)
AAQU: D3M96_15910
AAMM: FE795_13840
PHN: PAEH1_09765
ODI: ODI_R3894
ODH: DHf2319_11910
PIG: EGT29_00400
PACR: FXN63_06605
PARK: LSG25_03740 LSG25_13425
NARM: N7E01_02675
RHOB: HTY51_01175
POL: Bpro_4059
ACK: C380_01190
ARAD: KI609_01190
AAV: Aave_3926
AAA: Acav_3823
DAC: Daci_1854 Daci_3931
DEL: DelCs14_2885 DelCs14_4784
DTS: BI380_05635 BI380_15380
DHK: BO996_08780 BO996_17925
DLA: I6G47_04510 I6G47_15010
VAP: Vapar_0189
VPE: Varpa_0217
VPD: VAPA_1c02240
VAA: AX767_09740
VBO: CKY39_01185
VAM: C4F17_17885 C4F17_28475
CTT: CtCNB1_3770
CTES: O987_22820 O987_23170
AANT: HUK68_19205
CRJ: QMY55_00775 QMY55_18335
RTEA: HK414_09110
LIM: L103DPR2_00173(nicA_1) L103DPR2_00692(nicA_2)
HYN: F9K07_08775
DIH: G7047_00285
DAER: H9K75_17545
DRG: H9K76_16565
HGR: DW355_05290
ATER: MW290_16245 MW290_17445
HSE: Hsero_1322(iorA)
HSZ: ACP92_06615
HHT: F506_09950
HEE: hmeg3_15615 hmeg3_19245
HFR: G5S34_06825
MTIM: DIR46_18540 DIR46_21140
MFY: HH212_20510
MVAR: MasN3_42630
MFLA: GO485_02600
DUG: HH213_22815
DZO: SR858_15905
TMJ: P0M04_28985
XYK: GT347_16825
XYG: R9X41_15940
AZR: CJ010_22100
BEBA: BWI17_05515
MLN: A9174_33995
MOP: Mesop_2583
MESR: FGU64_15275
MES: Meso_1906
CHEA: PVE73_01625
SME: SM_b20403
SMK: Sinme_3775
SMQ: SinmeB_4271
SMX: SM11_pD1210
SMI: BN406_06269
SMEG: C770_GR4pD1199
SMEL: SM2011_b20403
SMER: DU99_31285
SFD: USDA257_c51590(iorA2)
ESJ: SJ05684_b50560
EAK: EKH55_5064
EMX: FKV68_33205
ENU: PYH37_001905
EGI: PZN02_005198
SKM: PZL22_001167
STEG: QA637_20270
EAD: OV14_b1100
RLG: Rleg_6040
RTR: RTCIAT899_PC08605
RGA: RGR602_PC02380
RJG: CCGE525_26730 CCGE525_29810
RAD: CO657_35855
RII: FFM53_028490
RRG: J3P73_36830
RLS: HB780_10930
RAW: NE851_01785
RSUL: N2599_21390 N2599_33990
RRHO: PR018_20405 PR018_21705
RTU: PR017_19760
ARA: Arad_8292(xdhA)
RBW: RLCC275e_26425
NGL: RG1141_PA14110
NGG: RG540_CH26740 RG540_PA15840
NEN: NCHU2750_46220(nicA)
NPM: QEO92_10625 QEO92_23990
SHZ: shn_22425
SSUM: Q9314_24305
BJA: bll3821(bll3821) blr6046(blr6046)
BJU: BJ6T_36570 BJ6T_60360
BJP: RN69_17730 RN69_29245
BRA: BRADO2115 BRADO3161
BBT: BBta_2424
BRS: S23_22240 S23_44210
AOL: S58_54190
BRC: BCCGELA001_15870
BRAD: BF49_1225 BF49_5582
BIC: LMTR13_10455 LMTR13_29575
BRO: BRAD285_5146
BRK: CWS35_16940
BOT: CIT37_24020 CIT37_34800
BRQ: CIT40_11905 CIT40_22230
BGQ: X265_12645 X265_24205
BGZ: XH91_11290 XH91_21390
BSYM: CIT39_11145 CIT39_21430
BBET: F8237_03115 F8237_26200
BARH: WN72_20525 WN72_33830
BVZ: BRAD3257_3073(nicA) BRAD3257_5215(nicA)
BEL: BE61_03770 BE61_16410 BE61_72870
BDG: LPJ38_21280
BSEP: HAP48_0029595
BQB: J4P68_0027990 J4P68_0030865
BSEI: KMZ68_20065
BBAN: J4G43_021095 J4G43_036305
BCAN: BcanWSM471_16550 BcanWSM471_26755
BAUT: QA635_03040 QA635_29745
BBRA: QA636_03080 QA636_31645
BGK: IC762_10220 IC762_34845
BCOU: IC761_06725 IC761_21965
BPAH: QA639_02980 QA639_14240
BXN: I3J27_15160 I3J27_26245
BROS: QUH67_11535 QUH67_26940
BRAZ: LRP30_16530 LRP30_27810
RPB: RPB_1668
RBK: E0H22_02820
NHA: Nham_1182
OCA: OCAR_7508
OCG: OCA5_c06290
OCO: OCA4_c06280
PCAX: AFIC_002245
TALZ: RPMA_03640
BOP: AXW83_08760 AXW83_24155
BOS: BSY19_2455
BOI: BLM15_19745
BOF: FQV39_30330
BVES: QO058_17430
XAU: Xaut_4210
XDI: EZH22_09205 EZH22_20080
AZC: AZC_2800
STAR: G3545_15130
APRA: G3A50_11860
APOL: K9D25_22345
MPO: Mpop_0236
MET: M446_3138
MNO: Mnod_8450
MAQU: Maq22A_1p38300(coxS) Maq22A_c03045(coxS)
MEE: DA075_03465 DA075_32190
METD: C0214_00675
METS: DK389_20535
MTEA: DK419_12580 DK419_23875
MIND: mvi_11820 mvi_18220
MTAD: M6G65_07750
MOC: BB934_38760
MSL: Msil_3375
RHZ: RHPLAN_07050 RHPLAN_11260 RHPLAN_35160 RHPLAN_51460
PLEO: OHA_2_00105(nicA)
HDI: HDIA_4148(nicA_1) HDIA_4442(nicA_2)
MMED: Mame_02898(nicA)
AUA: M673_15770
AUZ: Sa4125_40740
AUB: LXB15_07205
JIE: OH818_26800
JAV: OXU80_16170
PSIN: CAK95_00085 CAK95_18010
PPHR: APZ00_25405
PSTG: E8M01_24610
LIZ: LGH83_07400
CAUL: KCG34_06240
JAN: Jann_0874
RPON: G3256_05210
SMED: JNX03_08670
SAGU: CDO87_22415
PYE: A6J80_23240
PALW: PSAL_015660(nicA)
PSHQ: F3W81_00965
FAP: GR316_11010
NPP: PP1Y_Mpl8777
NHUM: PQ457_14430
SECH: B18_19795
SAER: NEF64_03465
SMOR: LHA26_16425
SQO: NMP03_06075
SHAN: PPZ50_09215
SNAP: PQ455_05100
SDON: M9980_05680
SABI: PBT88_16705
SYA: A6768_08040
ACOB: P0Y56_07565
GOY: GLS_c14200
GAL: A0U94_10330
GTI: FXF46_02590
GSP: IGS75_12395
ACR: Acry_3006
AMV: ACMV_33500
KSC: CD178_02881(nicA)
APT: APA01_23780
APW: APA42C_23780
APF: APA03_23780
APU: APA07_23780
APG: APA12_23780
APQ: APA22_23780
APX: APA26_23780
APZ: APA32_23780
APK: APA386B_1212(iorA)
ASV: WG31_11915
APOM: CPF11_08765
ATO: CIW82_09415
AASC: A4S02_13820
ACET: DS739_11645
ROS: CTJ15_00275
RMUC: FOB66_01420
RMT: IAI58_12910 IAI58_18380
RFL: Rmf_20230 Rmf_28810
SRF: LHU95_07645 LHU95_08455
NGU: QN315_05955 QN315_14000
SHUM: STHU_16280
SVC: STVA_18430
ALI: AZOLI_p20431
ABQ: ABAZ39_09540
AZT: TSH58p_07075
AZM: DM194_20110
AOZ: HUE56_03335 HUE56_08310
AARE: D3093_13980
AZS: E6C72_22650
SKT: IGS68_32650
SMUC: JL100_033685
SROE: JL101_031145
MAGX: XM1_1926(pucE)
MAGN: WV31_17390
MAG: amb1303
MYM: A176_000840
CCX: COCOR_06361(iorA2)
MFU: LILAB_16015
MMAS: MYMAC_005836
SUR: STAUR_8008
MBD: MEBOL_007950
CFUS: CYFUS_005901
CCRO: CMC5_078310
PARH: I5S86_12060
MSAK: MSAS_40510
MKU: I2456_03495
MLL: B1R94_09310
MMAG: MMAD_51030
MTY: MTOK_25970
SLIA: HA039_11990
NCA: Noca_4457
NOY: EXE57_13265
NPS: KRR39_16815
NMAR: HPC71_19725
NGN: LCN96_13275
ACE: Acel_0896
KUT: JJ691_53320
UME: RM788_06490
PLAB: C6361_08065
PLAT: C6W10_04630
OBG: Verru16b_02806(nicA_2)
NKO: Niako_5870
PSEG: D3H65_15520
SHG: Sph21_1188
OLI: FKG96_02875 FKG96_18055
BBD: Belba_3799
MDA: IPZ59_09745
RHOZ: GXP67_30565
DYC: NFI80_20885
DFQ: NFI81_22060
DCN: MUK70_26280
HQI: H9L05_17285
HTB: MTX78_12825
HSK: H4317_08435
HAEI: MUN82_05770
HVL: MUN86_13120
CLIT: OQ292_30215
IRO: RT717_15515
ZPR: ZPR_2975
AALG: AREALGSMS7_00647(nicA)
EMAR: D1013_18480
AFLA: FHG64_12520
 » show all
Reference
PMID:18678916
  Authors
Jimenez JI, Canales A, Jimenez-Barbero J, Ginalski K, Rychlewski L, Garcia JL, Diaz E
  Title
Deciphering the genetic determinants for aerobic nicotinic acid degradation: the nic cluster from Pseudomonas putida KT2440.
  Journal
Proc Natl Acad Sci U S A 105:11329-34 (2008)
DOI:10.1073/pnas.0802273105
  Sequence
[ppu:PP_3947]
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