KEGG   ORTHOLOGY: K18056
Entry
K18056                      KO                                     
Symbol
pntH, ptlH
Name
1-deoxypentalenic acid 11beta-hydroxylase [EC:1.14.11.35]
Pathway
map00998  Biosynthesis of various antibiotics
map01100  Metabolic pathways
map01110  Biosynthesis of secondary metabolites
Module
M00819  Pentalenolactone biosynthesis, farnesyl-PP => pentalenolactone
Reaction
R10157  1-deoxypentalenic acid,2-oxoglutarate:oxygen oxidoreductase
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09110 Biosynthesis of other secondary metabolites
   00998 Biosynthesis of various antibiotics
    K18056  pntH, ptlH; 1-deoxypentalenic acid 11beta-hydroxylase
Enzymes [BR:ko01000]
 1. Oxidoreductases
  1.14  Acting on paired donors, with incorporation or reduction of molecular oxygen
   1.14.11  With 2-oxoglutarate as one donor, and incorporation of one atom of oxygen into each donor
    1.14.11.35  1-deoxypentalenic acid 11beta-hydroxylase
     K18056  pntH, ptlH; 1-deoxypentalenic acid 11beta-hydroxylase
Genes
SMA: SAVERM_2991(ptlH)
SBH: SBI_09673
SCI: B446_29665
SCW: TU94_27375
SLE: sle_13220(sle_13220)
SSIA: A7J05_09270
SGJ: IAG43_27125
SHK: J2N69_35835
MTAR: DF168_00397 DF168_01555(ptlH_4)
DSN: HWI92_19215
DPF: ON006_25290
 » show all
Reference
PMID:16704250
  Authors
You Z, Omura S, Ikeda H, Cane DE
  Title
Pentalenolactone biosynthesis. Molecular cloning and assignment of biochemical function to PtlH, a non-heme iron dioxygenase of Streptomyces avermitilis.
  Journal
J Am Chem Soc 128:6566-7 (2006)
DOI:10.1021/ja061469i
  Sequence
[sma:SAVERM_2991]
LinkDB

DBGET integrated database retrieval system