KEGG   ORTHOLOGY: K18111
Entry
K18111                      KO                                     
Symbol
gcoA
Name
(+)-beta-caryophyllene/(+)-caryolan-1-ol synthase [EC:4.2.3.89 4.2.1.138]
Pathway
map00909  Sesquiterpenoid and triterpenoid biosynthesis
Reaction
R09835  (+)-beta-caryophyllene hydrolase [cyclizing, (+)-caryolan-1-ol-forming]
R09889  (2E,6E)-farnesyl-diphosphate diphosphate-lyase [cyclizing, (+)-beta-caryophyllene-forming]
Brite
KEGG Orthology (KO) [BR:ko00001]
 09100 Metabolism
  09109 Metabolism of terpenoids and polyketides
   00909 Sesquiterpenoid and triterpenoid biosynthesis
    K18111  gcoA; (+)-beta-caryophyllene/(+)-caryolan-1-ol synthase
Enzymes [BR:ko01000]
 4. Lyases
  4.2  Carbon-oxygen lyases
   4.2.1  Hydro-lyases
    4.2.1.138  (+)-caryolan-1-ol synthase
     K18111  gcoA; (+)-beta-caryophyllene/(+)-caryolan-1-ol synthase
   4.2.3  Acting on phosphates
    4.2.3.89  (+)-beta-caryophyllene synthase
     K18111  gcoA; (+)-beta-caryophyllene/(+)-caryolan-1-ol synthase
Genes
NTC: KHQ06_23155 KHQ06_27360 KHQ06_31745
SGR: SGR_2079
SGB: WQO_25120
SFI: SFUL_5260
SANL: KZO11_26645
SGRF: SGFS_066400
SCYE: R2B67_09240
SSX: SACTE_4655
SCZ: ABE83_10275
SVU: B1H20_25705
SCYG: S1361_14270(gcoA)
 » show all
Reference
  Authors
Nakano C, Horinouchi S, Ohnishi Y
  Title
Characterization of a novel sesquiterpene cyclase involved in (+)-caryolan-1-ol biosynthesis in Streptomyces griseus.
  Journal
J Biol Chem 286:27980-7 (2011)
DOI:10.1074/jbc.M111.265652
  Sequence
[sgr:SGR_2079]
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